Designing a New Entry Point into Isoprenoid Metabolism by Exploiting Fructose-6-Phosphate Aldolase Side Reactivity of Escherichia coli

ACS Synthetic Biology

Volumn 6, Issue 7, 2017, Pages 1416-1426

  King, Jason R ^a   Woolston, Benjamin M ^a   Stephanopoulos, Gregory ^a  

^a USA   (United States)

Author keywords

antibiotic resistance; biocatalysis; biosynthesis; isoprenoid; MEP pathway; metabolic engineering; promiscuity

Indexed keywords

1 DEXOXY DEXTRO XYLULOSE 5 PHOSPHATE; ARABINOSE; CARBON; DRUG METABOLITE; FRUCTOSE 6 PHOSPHATE; ISOPRENOID; LYCOPENE; TERPENE; UNCLASSIFIED DRUG; ESCHERICHIA COLI PROTEIN; FRUCTOSE PHOSPHATE; FRUCTOSE-6-PHOSPHATE; FSAA PROTEIN, E COLI; LYASE;

ARTICLE; CELL METABOLISM; CELL REPROGRAMMING TECHNIQUE; DRUG DESIGN; DRUG METABOLISM; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME SPECIFICITY; ESCHERICHIA COLI; METABOLIC ENGINEERING; NONHUMAN; PRIORITY JOURNAL; ANTIBIOTIC RESISTANCE; ENZYMOLOGY; METABOLISM; PROCEDURES;

ALDEHYDE-LYASES; DRUG RESISTANCE, MICROBIAL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FRUCTOSEPHOSPHATES; METABOLIC ENGINEERING; TERPENES;

EID: 85025163180     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/acssynbio.7b00072     Document Type: Article

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