Computational identification of gene over-expression targets for metabolic engineering of taxadiene production

Applied Microbiology and Biotechnology

Volumn 93, Issue 5, 2012, Pages 2063-2073

  Boghigian, Brett A ^a   Armando, John ^a   Salas, Daniel ^a   Pfeifer, Blaine A ^a  

^a Tufts University   (United States)

Author keywords

E. coli; Heterologous biosynthesis; Metabolic engineering; Over expression; Taxadiene; Taxadiene synthase; Taxol

Indexed keywords

E. COLI; OVER-EXPRESSION; TAXADIENE SYNTHASE; TAXADIENES; TAXOL;

BIOCHEMISTRY; BIOSYNTHESIS; ESCHERICHIA COLI; LIPIDS; METABOLIC ENGINEERING;

GENE EXPRESSION;

GLYCERALDEHYDE 3 PHOSPHATE; ISOPRENOID; PYRUVIC ACID; TAXADIENE; TERPENOID; UNCLASSIFIED DRUG;

BIOENGINEERING; COLIFORM BACTERIUM; GENE EXPRESSION;

ARTICLE; ESCHERICHIA COLI; GENE EXPRESSION; GENE IDENTIFICATION; GENE TARGETING; MATHEMATICAL COMPUTING; METABOLIC ENGINEERING;

ALKENES; COMPUTATIONAL BIOLOGY; DITERPENES; ESCHERICHIA COLI; GENE EXPRESSION; METABOLIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS;

ESCHERICHIA COLI;

EID: 84857918189     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-011-3725-1     Document Type: Article

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