Identification and microbial production of a terpene-based advanced biofuel

Nature Communications

Volumn 2, Issue 1, 2011, Pages

  Peralta Yahya, Pamela P ^a,b   Ouellet, Mario ^a,b   Chan, Rossana ^a,b   Mukhopadhyay, Aindrila ^a,b   Keasling, Jay D ^a,b,c   Lee, Taek Soon ^a,b  

^a JOINT BIOENERGY INSTITUTE   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOFUEL; BISABOLANE; BISABOLENE; DIESEL FUEL; FARNESYL DIPHOSPHATE; SYNTHETASE; TERPENE DERIVATIVE; UNCLASSIFIED DRUG; TERPENE;

ARTICLE; BIOMASS; BIOSYNTHESIS; ENZYME ANALYSIS; ESCHERICHIA COLI; HYDROGENATION; METABOLIC ENGINEERING; MICROORGANISM; NONHUMAN; SACCHAROMYCES CEREVISIAE; METABOLISM;

ESCHERICHIA COLI; SACCHAROMYCES CEREVISIAE;

BIOFUELS; ESCHERICHIA COLI; SACCHAROMYCES CEREVISIAE; TERPENES;

EID: 80053412686     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms1494     Document Type: Article

References (25)

1. United Nations Environment Programme ,. Towards sustainable production and use of resources-assessing biofuels ( www.unep.fr ; http://www.uneptie. org/energy/bioenergy/documents/pdf/Assessing%20Biofuels-Summary-Web-.pdf ) ( 2009 ).
2. Peralta-Yahya P. P. & Keasling J. D. Advanced biofuel production in microbes. Biotechnol. J. 5 147-162 ( 2010 ).
3. Fortman J. L. et al. Biofuel alternatives to ethanol: Pumping the microbial well. Trends Biotechnol. 2 6 375-381 ( 2008 ).
4. Kirby J. & Keasling J. D. Biosynthesis of plant isoprenoids: Perspectives for microbial engineering. Annu. Rev. Plant Biol. 6 0 335-355 ( 2009 ).
5. Rude M. & Schirmer A. New microbial fuels: A biotech perspective. C urr. Opin. Microbiol. 12 274-281 ( 2009 ).
6. Harvey B. G. Wright M. E. & Quintana R. L. High-density renewable fuels based on the selective dimerization of pinenes. Energ. Fuel. 2 4 267-273 ( 2010 ).
7. Renniger N. & McPhee D. Fuel compositions comprising farnesane and farnesane derivatives and method of making and using same. U.S. Patent No.7399323 ( 2008 ).
8. Martin V. J. Pitera D. J. Withers S. T. Newman J. D. & Keasling J. D. Engineering a mevalonate pathway in Escherichia coli for production of terpenoids. Nat. Biotechnol. 2 1 796-802 ( 2003 ). (Pubitemid 36791399)
9. Ro D. K. et al. Production of the antimalarial drug precursor artemisinic acid in engineered yeast. Nature 4 40 940-943 ( 2006 ).
10. Yoshikuni Y. Ferrin T. E. & Keasling J. D. Designed divergent evolution of enzyme function. Nature 440 1078-1082 ( 2006 ).
11. Ro D. K. et al. Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid. B MC Biotechnol. 8 83 ( 2008 ).
12. Redding-Johanson A. M. et al. Targeted proteomics for metabolic pathway optimization: Application to terpene production. Metab. Eng. 13 194-203 ( 2011 ).
13. Tsuruta H. et al. High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli. PLoS One 4 e4489 ( 2009 ).
14. Lee S. K. Chou H. Ham T. S. Lee T. S. & Keasling J. D. Metabolic engineering of microorganisms for biofuels production: From bugs to synthetic biology to fuels. C urr. Opin. Biotechnol. 1 9 556-563 ( 2008 ).
15. National Renewable Energy Laboratory. Biodiesel handling and use guide (Fourth Edition) ( www.nrel.gov ; http://www.nrel.gov/vehiclesandfuels/pdfs/ 43672.pdf ) ( 2009 ).
16. Anthony J. R. Anthony L. C. Nowroozi F. Kwon G. Newman J. D. & Keasling J. D. Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4,11-diene. M etab. Eng. 1 1 13-19 ( 2009 ).
17. Degenhardt J. Kollner T. G. & Gershenzon J. Monoterpene and sesquiterpene synthases and the origin of terpene skeletal diversity in plants. Phytochemistry 70 1621-1637 ( 2009 ).
18. Trapp S. C. & Croteau R. B. Genomic organization of plant terpene synthases and molecular evolutionary implications. Genetics 1 58 811-832 ( 2001 ). (Pubitemid 32564882)
19. Ro D. K. Ehlting J. Keeling C. I. Lin R. Mattheus N. & Bohlmann J. Microarray expression profi ling and functional characterization of AtTPS genes: Duplicated Arabidopsis thaliana sesquiterpene synthase genes At4g13280 and At4g13300 encode root-specifi c and wound-inducible (Z)-gamma-bisabolene synthases. Arch. Biochem. Biophys. 4 48 104-116 ( 2006 ).
20. Huber D. P. Philippe R. N. Godard K. A. Sturrock R. N. & Bohlmann J. Characterization of four terpene synthase cDNAs from methyl jasmonateinduced Douglas-fi r, Pseudotsuga menziesii. P hytochemistry 66 1427-1439 ( 2005 ). (Pubitemid 40793865)
21. Bohlmann J. Crock J. Jetter R. & Croteau R. Terpenoid-based defenses in conifers: CDNA cloning, characterization, and functional expression of woundinducible (E)-alpha-bisabolene synthase from grand fi r (A bies grandis ). P roc. Natl Acad. Sci. USA 9 5 6756-6761 ( 1998 ). (Pubitemid 28278053)
22. Martin D. M. F ä ldt J. & Bohlmann J. Functional characterization of nine Norway spruce TPS genes and evolution of gymnosperm terpene synthases of the TPS-d subfamily. P lant Physiol. 1 35 1908-1927 ( 2004 ). (Pubitemid 39182773)
23. Chang M. C. Eachus R. A. Trieu W. Ro D.-K. & Keasling J. D. Engineering Escherichia coli for production of functionalized terpenoids using plant P450s. Nat. Chem. Biol. 3 274-277 ( 2007 ). (Pubitemid 46625834)
24. Von Lampe P. Agricultural market impacts of future growth in the production of biofuels. Organization for Economic Co-operation and Development ( www. oecd.org ; www.oecd.org/dataoecd/58/62/36074135.pdf ) ( 2006 ).
25. Anderson J. C. et al. BglBricks: A fl exible standard for biological part assembly. J. Biol. Eng. 4 1 ( 2010 ).