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Volumn 41, Issue , 2018, Pages 40-53

The tolerogenic role of IFN-γ

Author keywords

autoimmune disease; cancer; graft versus host disease; immunosuppression; Interferon gamma; tolerance

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 17;

EID: 85045061461     PISSN: 13596101     EISSN: 18790305     Source Type: Journal    
DOI: 10.1016/j.cytogfr.2018.04.001     Document Type: Review
Times cited : (56)

References (169)
  • 1
    • 33845772515 scopus 로고
    • Interferon-Like Virus-Inhibitor Induced in Human Leukocytes by Phytohemagglutinin
    • Wheelock, E.F., Interferon-Like Virus-Inhibitor Induced in Human Leukocytes by Phytohemagglutinin. Science 149:3681 (1965), 310–311.
    • (1965) Science , vol.149 , Issue.3681 , pp. 310-311
    • Wheelock, E.F.1
  • 3
    • 0842266786 scopus 로고    scopus 로고
    • Interferon-gamma: an overview of signals, mechanisms and functions
    • Schroder, K., Hertzog, P.J., Ravasi, T., Hume, D.A., Interferon-gamma: an overview of signals, mechanisms and functions. J Leukoc Biol 75:2 (2004), 163–189.
    • (2004) J Leukoc Biol , vol.75 , Issue.2 , pp. 163-189
    • Schroder, K.1    Hertzog, P.J.2    Ravasi, T.3    Hume, D.A.4
  • 5
    • 0020502358 scopus 로고
    • Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity
    • Nathan, C.F., Murray, H.W., Wiebe, M.E., Rubin, B.Y., Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity. J Exp Med 158:3 (1983), 670–689.
    • (1983) J Exp Med , vol.158 , Issue.3 , pp. 670-689
    • Nathan, C.F.1    Murray, H.W.2    Wiebe, M.E.3    Rubin, B.Y.4
  • 6
    • 0028848472 scopus 로고
    • Role of interferon-gamma in immune cell regulation
    • Young, H.A., Hardy, K.J., Role of interferon-gamma in immune cell regulation. J Leukoc Biol 58:4 (1995), 373–381.
    • (1995) J Leukoc Biol , vol.58 , Issue.4 , pp. 373-381
    • Young, H.A.1    Hardy, K.J.2
  • 7
    • 0021928078 scopus 로고
    • Activation of mouse peritoneal macrophages in vitro and in vivo by interferon-gamma
    • Murray, H.W., Spitalny, G.L., Nathan, C.F., Activation of mouse peritoneal macrophages in vitro and in vivo by interferon-gamma. J Immunol 134:3 (1985), 1619–1622.
    • (1985) J Immunol , vol.134 , Issue.3 , pp. 1619-1622
    • Murray, H.W.1    Spitalny, G.L.2    Nathan, C.F.3
  • 8
    • 0027360333 scopus 로고
    • An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection
    • Flynn, J.L., Chan, J., Triebold, K.J., Dalton, D.K., Stewart, T.A., Bloom, B.R., An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection. J Exp Med 178:6 (1993), 2249–2254.
    • (1993) J Exp Med , vol.178 , Issue.6 , pp. 2249-2254
    • Flynn, J.L.1    Chan, J.2    Triebold, K.J.3    Dalton, D.K.4    Stewart, T.A.5    Bloom, B.R.6
  • 9
    • 0023895411 scopus 로고
    • Interferon-gamma: the major mediator of resistance against Toxoplasma gondii
    • Suzuki, Y., Orellana, M.A., Schreiber, R.D., Remington, J.S., Interferon-gamma: the major mediator of resistance against Toxoplasma gondii. Science 240:4851 (1988), 516–518.
    • (1988) Science , vol.240 , Issue.4851 , pp. 516-518
    • Suzuki, Y.1    Orellana, M.A.2    Schreiber, R.D.3    Remington, J.S.4
  • 10
    • 33750321707 scopus 로고    scopus 로고
    • Interferons, immunity and cancer immunoediting
    • Dunn, G.P., Koebel, C.M., Schreiber, R.D., Interferons, immunity and cancer immunoediting. Nat Rev Immunol 6:11 (2006), 836–884.
    • (2006) Nat Rev Immunol , vol.6 , Issue.11 , pp. 836-884
    • Dunn, G.P.1    Koebel, C.M.2    Schreiber, R.D.3
  • 12
    • 0037066427 scopus 로고    scopus 로고
    • The danger model: a renewed sense of self
    • Matzinger, P., The danger model: a renewed sense of self. Science 296:5566 (2002), 301–305.
    • (2002) Science , vol.296 , Issue.5566 , pp. 301-305
    • Matzinger, P.1
  • 13
  • 14
    • 84897018300 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells: molecular and cellular mechanisms in transplantation
    • Svajger, U., Rozman, P., Tolerogenic dendritic cells: molecular and cellular mechanisms in transplantation. J Leukoc Biol 95:1 (2014), 53–69.
    • (2014) J Leukoc Biol , vol.95 , Issue.1 , pp. 53-69
    • Svajger, U.1    Rozman, P.2
  • 15
    • 78650992800 scopus 로고    scopus 로고
    • Type-1 polarized dendritic cells loaded with apoptotic prostate cancer cells are potent inducers of CD8(+) T cells against prostate cancer cells and defined prostate cancer-specific epitopes
    • Wieckowski, E., Chatta, G.S., Mailliard, R.M., Gooding, W., Palucka, K., Banchereau, J., Kalinski, P., Type-1 polarized dendritic cells loaded with apoptotic prostate cancer cells are potent inducers of CD8(+) T cells against prostate cancer cells and defined prostate cancer-specific epitopes. Prostate 71:2 (2011), 125–133.
    • (2011) Prostate , vol.71 , Issue.2 , pp. 125-133
    • Wieckowski, E.1    Chatta, G.S.2    Mailliard, R.M.3    Gooding, W.4    Palucka, K.5    Banchereau, J.6    Kalinski, P.7
  • 16
    • 0034193991 scopus 로고    scopus 로고
    • Development of Th1-inducing capacity in myeloid dendritic cells requires environmental instruction
    • Vieira, P.L., de Jong, E.C., Wierenga, E.A., Kapsenberg, M.L., Kalinski, P., Development of Th1-inducing capacity in myeloid dendritic cells requires environmental instruction. J Immunol 164:9 (2000), 4507–4512.
    • (2000) J Immunol , vol.164 , Issue.9 , pp. 4507-4512
    • Vieira, P.L.1    de Jong, E.C.2    Wierenga, E.A.3    Kapsenberg, M.L.4    Kalinski, P.5
  • 17
    • 19344377474 scopus 로고    scopus 로고
    • GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase
    • Munn, D.H., Sharma, M.D., Baban, B., Harding, H.P., Zhang, Y., Ron, D., Mellor, A.L., GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase. Immunity 22:5 (2005), 633–642.
    • (2005) Immunity , vol.22 , Issue.5 , pp. 633-642
    • Munn, D.H.1    Sharma, M.D.2    Baban, B.3    Harding, H.P.4    Zhang, Y.5    Ron, D.6    Mellor, A.L.7
  • 19
    • 84875261622 scopus 로고    scopus 로고
    • Indoleamine 2,3 dioxygenase and metabolic control of immune responses
    • Munn, D.H., Mellor, A.L., Indoleamine 2,3 dioxygenase and metabolic control of immune responses. Trends Immunol 34:3 (2013), 137–143.
    • (2013) Trends Immunol , vol.34 , Issue.3 , pp. 137-143
    • Munn, D.H.1    Mellor, A.L.2
  • 20
    • 70350433798 scopus 로고    scopus 로고
    • Interferon-gamma-triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells
    • Jurgens, B., Hainz, U., Fuchs, D., Felzmann, T., Heitger, A., Interferon-gamma-triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells. Blood 114:15 (2009), 3235–3243.
    • (2009) Blood , vol.114 , Issue.15 , pp. 3235-3243
    • Jurgens, B.1    Hainz, U.2    Fuchs, D.3    Felzmann, T.4    Heitger, A.5
  • 21
    • 84979536652 scopus 로고    scopus 로고
    • Tolerogenic Phenotype of IFN-gamma-Induced IDO+ Dendritic Cells Is Maintained via an Autocrine IDO-Kynurenine/AhR-IDO Loop
    • Li, Q., Harden, J.L., Anderson, C.D., Egilmez, N.K., Tolerogenic Phenotype of IFN-gamma-Induced IDO+ Dendritic Cells Is Maintained via an Autocrine IDO-Kynurenine/AhR-IDO Loop. J Immunol 197:3 (2016), 962–970.
    • (2016) J Immunol , vol.197 , Issue.3 , pp. 962-970
    • Li, Q.1    Harden, J.L.2    Anderson, C.D.3    Egilmez, N.K.4
  • 23
    • 0347359059 scopus 로고    scopus 로고
    • Therapeutic potential of IFN-gamma-modified dendritic cells in acute and chronic experimental allergic encephalomyelitis
    • Xiao, B.G., Wu, X.C., Yang, J.S., Xu, L.Y., Liu, X., Huang, Y.M., Bjelke, B., Link, H., Therapeutic potential of IFN-gamma-modified dendritic cells in acute and chronic experimental allergic encephalomyelitis. Int Immunol 16:1 (2004), 13–22.
    • (2004) Int Immunol , vol.16 , Issue.1 , pp. 13-22
    • Xiao, B.G.1    Wu, X.C.2    Yang, J.S.3    Xu, L.Y.4    Liu, X.5    Huang, Y.M.6    Bjelke, B.7    Link, H.8
  • 24
    • 84897018841 scopus 로고    scopus 로고
    • IFN-gamma-rich environment programs dendritic cells toward silencing of cytotoxic immune responses
    • Svajger, U., Obermajer, N., Jeras, M., IFN-gamma-rich environment programs dendritic cells toward silencing of cytotoxic immune responses. J Leukoc Biol 95:1 (2014), 33–46.
    • (2014) J Leukoc Biol , vol.95 , Issue.1 , pp. 33-46
    • Svajger, U.1    Obermajer, N.2    Jeras, M.3
  • 25
    • 0037261143 scopus 로고    scopus 로고
    • Soluble HLA-A,-B,-C and -G molecules induce apoptosis in T and NK CD8+ cells and inhibit cytotoxic T cell activity through CD8 ligation
    • Contini, P., Ghio, M., Poggi, A., Filaci, G., Indiveri, F., Ferrone, S., Puppo, F., Soluble HLA-A,-B,-C and -G molecules induce apoptosis in T and NK CD8+ cells and inhibit cytotoxic T cell activity through CD8 ligation. Eur J Immunol 33:1 (2003), 125–134.
    • (2003) Eur J Immunol , vol.33 , Issue.1 , pp. 125-134
    • Contini, P.1    Ghio, M.2    Poggi, A.3    Filaci, G.4    Indiveri, F.5    Ferrone, S.6    Puppo, F.7
  • 27
    • 65749103365 scopus 로고    scopus 로고
    • The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
    • Koch, M.A., Tucker-Heard, G., Perdue, N.R., Killebrew, J.R., Urdahl, K.B., Campbell, D.J., The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation. Nat Immunol 10:6 (2009), 595–602.
    • (2009) Nat Immunol , vol.10 , Issue.6 , pp. 595-602
    • Koch, M.A.1    Tucker-Heard, G.2    Perdue, N.R.3    Killebrew, J.R.4    Urdahl, K.B.5    Campbell, D.J.6
  • 28
    • 84896704750 scopus 로고    scopus 로고
    • Homeostatic control of regulatory T cell diversity
    • Liston, A., Gray, D.H., Homeostatic control of regulatory T cell diversity. Nat Rev Immunol 14:3 (2014), 154–165.
    • (2014) Nat Rev Immunol , vol.14 , Issue.3 , pp. 154-165
    • Liston, A.1    Gray, D.H.2
  • 29
    • 78650374915 scopus 로고    scopus 로고
    • Generation of human Th1-like regulatory CD4+ T cells by an intrinsic IFN-gamma- and T-bet-dependent pathway
    • Zheng, J., Liu, Y., Qin, G., Lam, K.T., Guan, J., Xiang, Z., Lewis, D.B., Lau, Y.L., Tu, W., Generation of human Th1-like regulatory CD4+ T cells by an intrinsic IFN-gamma- and T-bet-dependent pathway. Eur J Immunol 41:1 (2011), 128–139.
    • (2011) Eur J Immunol , vol.41 , Issue.1 , pp. 128-139
    • Zheng, J.1    Liu, Y.2    Qin, G.3    Lam, K.T.4    Guan, J.5    Xiang, Z.6    Lewis, D.B.7    Lau, Y.L.8    Tu, W.9
  • 30
    • 55249099643 scopus 로고    scopus 로고
    • Exogenous IFN-gamma ex vivo shapes the alloreactive T-cell repertoire by inhibition of Th17 responses and generation of functional Foxp3+ regulatory T cells
    • Feng, G., Gao, W., Strom, T.B., Oukka, M., Francis, R.S., Wood, K.J., Bushell, A., Exogenous IFN-gamma ex vivo shapes the alloreactive T-cell repertoire by inhibition of Th17 responses and generation of functional Foxp3+ regulatory T cells. Eur J Immunol 38:9 (2008), 2512–2527.
    • (2008) Eur J Immunol , vol.38 , Issue.9 , pp. 2512-2527
    • Feng, G.1    Gao, W.2    Strom, T.B.3    Oukka, M.4    Francis, R.S.5    Wood, K.J.6    Bushell, A.7
  • 32
    • 80555154007 scopus 로고    scopus 로고
    • SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-{gamma} and IL-17A production
    • Takahashi, R., Nishimoto, S., Muto, G., Sekiya, T., Tamiya, T., Kimura, A., Morita, R., Asakawa, M., Chinen, T., Yoshimura, A., SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-{gamma} and IL-17A production. J Exp Med 208:10 (2011), 2055–2067.
    • (2011) J Exp Med , vol.208 , Issue.10 , pp. 2055-2067
    • Takahashi, R.1    Nishimoto, S.2    Muto, G.3    Sekiya, T.4    Tamiya, T.5    Kimura, A.6    Morita, R.7    Asakawa, M.8    Chinen, T.9    Yoshimura, A.10
  • 33
    • 22344434572 scopus 로고    scopus 로고
    • IFN-gamma production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo
    • Sawitzki, B., Kingsley, C.I., Oliveira, V., Karim, M., Herber, M., Wood, K.J., IFN-gamma production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo. J Exp Med 201:12 (2005), 1925–1935.
    • (2005) J Exp Med , vol.201 , Issue.12 , pp. 1925-1935
    • Sawitzki, B.1    Kingsley, C.I.2    Oliveira, V.3    Karim, M.4    Herber, M.5    Wood, K.J.6
  • 34
    • 45449086892 scopus 로고    scopus 로고
    • Observational support for an immunoregulatory role of CD3+CD4+CD25+IFN-gamma+ blood lymphocytes in kidney transplant recipients with good long-term graft outcome
    • Daniel, V., Naujokat, C., Sadeghi, M., Weimer, R., Renner, F., Yildiz, S., Opelz, G., Observational support for an immunoregulatory role of CD3+CD4+CD25+IFN-gamma+ blood lymphocytes in kidney transplant recipients with good long-term graft outcome. Transpl Int 21:7 (2008), 646–660.
    • (2008) Transpl Int , vol.21 , Issue.7 , pp. 646-660
    • Daniel, V.1    Naujokat, C.2    Sadeghi, M.3    Weimer, R.4    Renner, F.5    Yildiz, S.6    Opelz, G.7
  • 35
    • 78650307252 scopus 로고    scopus 로고
    • Transplant long-surviving induced by CD40-CD40 ligand costimulation blockade is dependent on IFN-gamma through its effect on CD4(+)CD25(+) regulatory T cells
    • Jiang, X.F., Zhu, L., Cui, Z.M., Guo, D.W., Sun, W.Y., Lin, L., Tang, Y.F., Wang, X.F., Liang, J., Transplant long-surviving induced by CD40-CD40 ligand costimulation blockade is dependent on IFN-gamma through its effect on CD4(+)CD25(+) regulatory T cells. Transpl Immunol 24:2 (2011), 113–118.
    • (2011) Transpl Immunol , vol.24 , Issue.2 , pp. 113-118
    • Jiang, X.F.1    Zhu, L.2    Cui, Z.M.3    Guo, D.W.4    Sun, W.Y.5    Lin, L.6    Tang, Y.F.7    Wang, X.F.8    Liang, J.9
  • 37
    • 84884239709 scopus 로고    scopus 로고
    • The interdependent, overlapping, and differential roles of type I and II IFNs in the pathogenesis of experimental autoimmune encephalomyelitis
    • Naves, R., Singh, S.P., Cashman, K.S., Rowse, A.L., Axtell, R.C., Steinman, L., Mountz, J.D., Steele, C., De Sarno, P., Raman, C., The interdependent, overlapping, and differential roles of type I and II IFNs in the pathogenesis of experimental autoimmune encephalomyelitis. J Immunol 191:6 (2013), 2967–2977.
    • (2013) J Immunol , vol.191 , Issue.6 , pp. 2967-2977
    • Naves, R.1    Singh, S.P.2    Cashman, K.S.3    Rowse, A.L.4    Axtell, R.C.5    Steinman, L.6    Mountz, J.D.7    Steele, C.8    De Sarno, P.9    Raman, C.10
  • 38
    • 0033119188 scopus 로고    scopus 로고
    • Differential role of TNF-alpha and IFN-gamma in the brain of rats with chronic relapsing autoimmune encephalomyelitis
    • Tanuma, N., Shin, T., Kogure, K., Matsumoto, Y., Differential role of TNF-alpha and IFN-gamma in the brain of rats with chronic relapsing autoimmune encephalomyelitis. J Neuroimmunol 96:1 (1999), 73–79.
    • (1999) J Neuroimmunol , vol.96 , Issue.1 , pp. 73-79
    • Tanuma, N.1    Shin, T.2    Kogure, K.3    Matsumoto, Y.4
  • 39
    • 0035423415 scopus 로고    scopus 로고
    • Intrathecal delivery of IFN-gamma protects C57BL/6 mice from chronic-progressive experimental autoimmune encephalomyelitis by increasing apoptosis of central nervous system-infiltrating lymphocytes
    • Furlan, R., Brambilla, E., Ruffini, F., Poliani, P.L., Bergami, A., Marconi, P.C., Franciotta, D.M., Penna, G., Comi, G., Adorini, L., Martino, G., Intrathecal delivery of IFN-gamma protects C57BL/6 mice from chronic-progressive experimental autoimmune encephalomyelitis by increasing apoptosis of central nervous system-infiltrating lymphocytes. J Immunol 167:3 (2001), 1821–1829.
    • (2001) J Immunol , vol.167 , Issue.3 , pp. 1821-1829
    • Furlan, R.1    Brambilla, E.2    Ruffini, F.3    Poliani, P.L.4    Bergami, A.5    Marconi, P.C.6    Franciotta, D.M.7    Penna, G.8    Comi, G.9    Adorini, L.10    Martino, G.11
  • 40
    • 0026697915 scopus 로고
    • Cytokines in neuroinflammatory disease: role of myelin autoreactive T cell production of interferon-gamma
    • Olsson, T., Cytokines in neuroinflammatory disease: role of myelin autoreactive T cell production of interferon-gamma. J Neuroimmunol 40:2-3 (1992), 211–218.
    • (1992) J Neuroimmunol , vol.40 , Issue.2-3 , pp. 211-218
    • Olsson, T.1
  • 41
    • 77956536780 scopus 로고    scopus 로고
    • T cells in multiple sclerosis and experimental autoimmune encephalomyelitis
    • Fletcher, J.M., Lalor, S.J., Sweeney, C.M., Tubridy, N., Mills, K.H., T cells in multiple sclerosis and experimental autoimmune encephalomyelitis. Clin Exp Immunol 162:1 (2010), 1–11.
    • (2010) Clin Exp Immunol , vol.162 , Issue.1 , pp. 1-11
    • Fletcher, J.M.1    Lalor, S.J.2    Sweeney, C.M.3    Tubridy, N.4    Mills, K.H.5
  • 42
    • 46049093364 scopus 로고    scopus 로고
    • Th17 Cells and autoimmune encephalomyelitis (EAE/MS)
    • Aranami, T., Yamamura, T., Th17 Cells and autoimmune encephalomyelitis (EAE/MS),. Allergol Int 57:2 (2008), 115–120.
    • (2008) Allergol Int , vol.57 , Issue.2 , pp. 115-120
    • Aranami, T.1    Yamamura, T.2
  • 43
    • 84896542936 scopus 로고    scopus 로고
    • Th17 and regulatory T cell balance in autoimmune and inflammatory diseases
    • Noack, M., Miossec, P., Th17 and regulatory T cell balance in autoimmune and inflammatory diseases. Autoimmun Rev 13:6 (2014), 668–677.
    • (2014) Autoimmun Rev , vol.13 , Issue.6 , pp. 668-677
    • Noack, M.1    Miossec, P.2
  • 44
    • 79960110182 scopus 로고    scopus 로고
    • Interferon-gamma orchestrates the number and function of Th17 cells in experimental autoimmune encephalomyelitis
    • Berghmans, N., Nuyts, A., Uyttenhove, C., Van Snick, J., Opdenakker, G., Heremans, H., Interferon-gamma orchestrates the number and function of Th17 cells in experimental autoimmune encephalomyelitis. J Interferon Cytokine Res 31:7 (2011), 575–587.
    • (2011) J Interferon Cytokine Res , vol.31 , Issue.7 , pp. 575-587
    • Berghmans, N.1    Nuyts, A.2    Uyttenhove, C.3    Van Snick, J.4    Opdenakker, G.5    Heremans, H.6
  • 45
    • 0023879766 scopus 로고
    • Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma
    • Billiau, A., Heremans, H., Vandekerckhove, F., Dijkmans, R., Sobis, H., Meulepas, E., Carton, H., Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma. J Immunol 140:5 (1988), 1506–1510.
    • (1988) J Immunol , vol.140 , Issue.5 , pp. 1506-1510
    • Billiau, A.1    Heremans, H.2    Vandekerckhove, F.3    Dijkmans, R.4    Sobis, H.5    Meulepas, E.6    Carton, H.7
  • 46
    • 0029829385 scopus 로고    scopus 로고
    • Chronic relapsing experimental autoimmune encephalomyelitis (CREAE) in mice: enhancement by monoclonal antibodies against interferon-gamma
    • Heremans, H., Dillen, C., Groenen, M., Martens, E., Billiau, A., Chronic relapsing experimental autoimmune encephalomyelitis (CREAE) in mice: enhancement by monoclonal antibodies against interferon-gamma. Eur J Immunol 26:10 (1996), 2393–2398.
    • (1996) Eur J Immunol , vol.26 , Issue.10 , pp. 2393-2398
    • Heremans, H.1    Dillen, C.2    Groenen, M.3    Martens, E.4    Billiau, A.5
  • 47
    • 78951491805 scopus 로고    scopus 로고
    • Interleukin-27 and interferon-gamma are involved in regulation of autoimmune arthritis
    • Rajaiah, R., Puttabyatappa, M., Polumuri, S.K., Moudgil, K.D., Interleukin-27 and interferon-gamma are involved in regulation of autoimmune arthritis. J Biol Chem 286:4 (2011), 2817–2825.
    • (2011) J Biol Chem , vol.286 , Issue.4 , pp. 2817-2825
    • Rajaiah, R.1    Puttabyatappa, M.2    Polumuri, S.K.3    Moudgil, K.D.4
  • 48
    • 77954939162 scopus 로고    scopus 로고
    • Identification of an IL-27/osteopontin axis in dendritic cells and its modulation by IFN-gamma limits IL-17-mediated autoimmune inflammation
    • Murugaiyan, G., Mittal, A., Weiner, H.L., Identification of an IL-27/osteopontin axis in dendritic cells and its modulation by IFN-gamma limits IL-17-mediated autoimmune inflammation. Proc Natl Acad Sci U S A 107:25 (2010), 11495–11500.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.25 , pp. 11495-11500
    • Murugaiyan, G.1    Mittal, A.2    Weiner, H.L.3
  • 50
    • 84873638253 scopus 로고    scopus 로고
    • Th9 cells: differentiation and disease
    • Kaplan, M.H., Th9 cells: differentiation and disease. Immunol Rev 252:1 (2013), 104–115.
    • (2013) Immunol Rev , vol.252 , Issue.1 , pp. 104-115
    • Kaplan, M.H.1
  • 51
    • 84995493924 scopus 로고    scopus 로고
    • Th9 cells in the pathogenesis of EAE and multiple sclerosis
    • Elyaman, W., Khoury, S.J., Th9 cells in the pathogenesis of EAE and multiple sclerosis. Semin Immunopathol 39:1 (2017), 79–87.
    • (2017) Semin Immunopathol , vol.39 , Issue.1 , pp. 79-87
    • Elyaman, W.1    Khoury, S.J.2
  • 52
    • 84869806031 scopus 로고    scopus 로고
    • IFN-gamma limits Th9-mediated autoimmune inflammation through dendritic cell modulation of IL-27
    • Murugaiyan, G., Beynon, V., Pires Da Cunha, A., Joller, N., Weiner, H.L., IFN-gamma limits Th9-mediated autoimmune inflammation through dendritic cell modulation of IL-27. J Immunol 189:11 (2012), 5277–5283.
    • (2012) J Immunol , vol.189 , Issue.11 , pp. 5277-5283
    • Murugaiyan, G.1    Beynon, V.2    Pires Da Cunha, A.3    Joller, N.4    Weiner, H.L.5
  • 53
    • 0031156936 scopus 로고    scopus 로고
    • Accelerated collagen-induced arthritis in IFN-gamma receptor-deficient mice
    • Vermeire, K., Heremans, H., Vandeputte, M., Huang, S., Billiau, A., Matthys, P., Accelerated collagen-induced arthritis in IFN-gamma receptor-deficient mice. J Immunol 158:11 (1997), 5507–5513.
    • (1997) J Immunol , vol.158 , Issue.11 , pp. 5507-5513
    • Vermeire, K.1    Heremans, H.2    Vandeputte, M.3    Huang, S.4    Billiau, A.5    Matthys, P.6
  • 54
    • 30144433577 scopus 로고    scopus 로고
    • Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-gamma
    • Kelchtermans, H., De Klerck, B., Mitera, T., Van Balen, M., Bullens, D., Billiau, A., Leclercq, G., Matthys, P., Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-gamma. Arthritis Res Ther 7:2 (2005), R402–R415.
    • (2005) Arthritis Res Ther , vol.7 , Issue.2 , pp. R402-R415
    • Kelchtermans, H.1    De Klerck, B.2    Mitera, T.3    Van Balen, M.4    Bullens, D.5    Billiau, A.6    Leclercq, G.7    Matthys, P.8
  • 55
    • 19744361931 scopus 로고    scopus 로고
    • Enhanced osteoclast development in collagen-induced arthritis in interferon-gamma receptor knock-out mice as related to increased splenic CD11b+ myelopoiesis
    • De Klerck, B., Carpentier, I., Lories, R.J., Habraken, Y., Piette, J., Carmeliet, G., Beyaert, R., Billiau, A., Matthys, P., Enhanced osteoclast development in collagen-induced arthritis in interferon-gamma receptor knock-out mice as related to increased splenic CD11b+ myelopoiesis. Arthritis Res Ther 6:3 (2004), R220–R231.
    • (2004) Arthritis Res Ther , vol.6 , Issue.3 , pp. R220-R231
    • De Klerck, B.1    Carpentier, I.2    Lories, R.J.3    Habraken, Y.4    Piette, J.5    Carmeliet, G.6    Beyaert, R.7    Billiau, A.8    Matthys, P.9
  • 58
    • 40849135483 scopus 로고    scopus 로고
    • Regulation of autoimmune arthritis by the pro-inflammatory cytokine interferon-gamma
    • Kim, E.Y., Chi, H.H., Bouziane, M., Gaur, A., Moudgil, K.D., Regulation of autoimmune arthritis by the pro-inflammatory cytokine interferon-gamma. Clin Immunol 127:1 (2008), 98–106.
    • (2008) Clin Immunol , vol.127 , Issue.1 , pp. 98-106
    • Kim, E.Y.1    Chi, H.H.2    Bouziane, M.3    Gaur, A.4    Moudgil, K.D.5
  • 59
    • 58249118715 scopus 로고    scopus 로고
    • Tolerization with Hsp65 induces protection against adjuvant-induced arthritis by modulating the antigen-directed interferon-gamma, interleukin-17, and antibody responses
    • Satpute, S.R., Rajaiah, R., Polumuri, S.K., Moudgil, K.D., Tolerization with Hsp65 induces protection against adjuvant-induced arthritis by modulating the antigen-directed interferon-gamma, interleukin-17, and antibody responses. Arthritis Rheum 60:1 (2009), 103–113.
    • (2009) Arthritis Rheum , vol.60 , Issue.1 , pp. 103-113
    • Satpute, S.R.1    Rajaiah, R.2    Polumuri, S.K.3    Moudgil, K.D.4
  • 60
    • 0032939156 scopus 로고    scopus 로고
    • Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium
    • Chabaud, M., Durand, J.M., Buchs, N., Fossiez, F., Page, G., Frappart, L., Miossec, P., Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium. Arthritis Rheum 42:5 (1999), 963–970.
    • (1999) Arthritis Rheum , vol.42 , Issue.5 , pp. 963-970
    • Chabaud, M.1    Durand, J.M.2    Buchs, N.3    Fossiez, F.4    Page, G.5    Frappart, L.6    Miossec, P.7
  • 62
    • 0344585384 scopus 로고    scopus 로고
    • Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
    • Nakae, S., Nambu, A., Sudo, K., Iwakura, Y., Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J Immunol 171:11 (2003), 6173–6177.
    • (2003) J Immunol , vol.171 , Issue.11 , pp. 6173-6177
    • Nakae, S.1    Nambu, A.2    Sudo, K.3    Iwakura, Y.4
  • 63
    • 5644277476 scopus 로고    scopus 로고
    • Interleukin-17 family members and inflammation
    • Kolls, J.K., Linden, A., Interleukin-17 family members and inflammation. Immunity 21:4 (2004), 467–476.
    • (2004) Immunity , vol.21 , Issue.4 , pp. 467-476
    • Kolls, J.K.1    Linden, A.2
  • 64
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • Harrington, L.E., Hatton, R.D., Mangan, P.R., Turner, H., Murphy, T.L., Murphy, K.M., Weaver, C.T., Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 6:11 (2005), 1123–1132.
    • (2005) Nat Immunol , vol.6 , Issue.11 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3    Turner, H.4    Murphy, T.L.5    Murphy, K.M.6    Weaver, C.T.7
  • 66
    • 69849090650 scopus 로고    scopus 로고
    • Effector mechanisms of interleukin-17 in collagen-induced arthritis in the absence of interferon-gamma and counteraction by interferon-gamma
    • Kelchtermans, H., Schurgers, E., Geboes, L., Mitera, T., Van Damme, J., Van Snick, J., Uyttenhove, C., Matthys, P., Effector mechanisms of interleukin-17 in collagen-induced arthritis in the absence of interferon-gamma and counteraction by interferon-gamma. Arthritis Res Ther, 11(4), 2009, R122.
    • (2009) Arthritis Res Ther , vol.11 , Issue.4 , pp. R122
    • Kelchtermans, H.1    Schurgers, E.2    Geboes, L.3    Mitera, T.4    Van Damme, J.5    Van Snick, J.6    Uyttenhove, C.7    Matthys, P.8
  • 67
    • 84875710026 scopus 로고    scopus 로고
    • Interleukin-22 reduces the severity of collagen-induced arthritis in association with increased levels of interleukin-10
    • Sarkar, S., Zhou, X., Justa, S., Bommireddy, S.R., Interleukin-22 reduces the severity of collagen-induced arthritis in association with increased levels of interleukin-10. Arthritis Rheum 65:4 (2013), 960–971.
    • (2013) Arthritis Rheum , vol.65 , Issue.4 , pp. 960-971
    • Sarkar, S.1    Zhou, X.2    Justa, S.3    Bommireddy, S.R.4
  • 68
    • 0032941175 scopus 로고    scopus 로고
    • Interferon-gamma (IFN-gamma)- and tumour necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice
    • Obermeier, F., Kojouharoff, G., Hans, W., Scholmerich, J., Gross, V., Falk, W., Interferon-gamma (IFN-gamma)- and tumour necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice. Clin Exp Immunol 116:2 (1999), 238–245.
    • (1999) Clin Exp Immunol , vol.116 , Issue.2 , pp. 238-245
    • Obermeier, F.1    Kojouharoff, G.2    Hans, W.3    Scholmerich, J.4    Gross, V.5    Falk, W.6
  • 70
    • 0041845066 scopus 로고    scopus 로고
    • Inhibition of IFN-gamma-inducible protein-10 abrogates colitis in IL-10-/- mice
    • Singh, U.P., Singh, S., Taub, D.D., Lillard, J.W. Jr., Inhibition of IFN-gamma-inducible protein-10 abrogates colitis in IL-10-/- mice,. J Immunol 171:3 (2003), 1401–1406.
    • (2003) J Immunol , vol.171 , Issue.3 , pp. 1401-1406
    • Singh, U.P.1    Singh, S.2    Taub, D.D.3    Lillard, J.W.4
  • 74
    • 0032530697 scopus 로고    scopus 로고
    • IL-12, but not IFN-gamma, plays a major role in sustaining the chronic phase of colitis in IL-10-deficient mice
    • Davidson, N.J., Hudak, S.A., Lesley, R.E., Menon, S., Leach, M.W., Rennick, D.M., IL-12, but not IFN-gamma, plays a major role in sustaining the chronic phase of colitis in IL-10-deficient mice. J Immunol 161:6 (1998), 3143–3149.
    • (1998) J Immunol , vol.161 , Issue.6 , pp. 3143-3149
    • Davidson, N.J.1    Hudak, S.A.2    Lesley, R.E.3    Menon, S.4    Leach, M.W.5    Rennick, D.M.6
  • 76
    • 44349124113 scopus 로고    scopus 로고
    • The genetics and immunopathogenesis of inflammatory bowel disease
    • Cho, J.H., The genetics and immunopathogenesis of inflammatory bowel disease. Nat Rev Immunol 8:6 (2008), 458–466.
    • (2008) Nat Rev Immunol , vol.8 , Issue.6 , pp. 458-466
    • Cho, J.H.1
  • 77
    • 77952784918 scopus 로고    scopus 로고
    • Cutting edge: IFN-gamma is a negative regulator of IL-23 in murine macrophages and experimental colitis
    • Sheikh, S.Z., Matsuoka, K., Kobayashi, T., Li, F., Rubinas, T., Plevy, S.E., Cutting edge: IFN-gamma is a negative regulator of IL-23 in murine macrophages and experimental colitis. J Immunol 184:8 (2010), 4069–4073.
    • (2010) J Immunol , vol.184 , Issue.8 , pp. 4069-4073
    • Sheikh, S.Z.1    Matsuoka, K.2    Kobayashi, T.3    Li, F.4    Rubinas, T.5    Plevy, S.E.6
  • 78
    • 84901410158 scopus 로고    scopus 로고
    • Intestinal macrophages and dendritic cells: what's the difference?
    • Cerovic, V., Bain, C.C., Mowat, A.M., Milling, S.W., Intestinal macrophages and dendritic cells: what's the difference?. Trends Immunol 35:6 (2014), 270–277.
    • (2014) Trends Immunol , vol.35 , Issue.6 , pp. 270-277
    • Cerovic, V.1    Bain, C.C.2    Mowat, A.M.3    Milling, S.W.4
  • 79
    • 84961773640 scopus 로고    scopus 로고
    • Intestinal CD103(+)CD11b(-) dendritic cells restrain colitis via IFN-gamma-induced anti-inflammatory response in epithelial cells
    • Muzaki, A.R., Tetlak, P., Sheng, J., Loh, S.C., Setiagani, Y.A., Poidinger, M., Zolezzi, F., Karjalainen, K., Ruedl, C., Intestinal CD103(+)CD11b(-) dendritic cells restrain colitis via IFN-gamma-induced anti-inflammatory response in epithelial cells. Mucosal Immunol 9:2 (2016), 336–351.
    • (2016) Mucosal Immunol , vol.9 , Issue.2 , pp. 336-351
    • Muzaki, A.R.1    Tetlak, P.2    Sheng, J.3    Loh, S.C.4    Setiagani, Y.A.5    Poidinger, M.6    Zolezzi, F.7    Karjalainen, K.8    Ruedl, C.9
  • 82
    • 84918573907 scopus 로고    scopus 로고
    • Atypical MHC class II-expressing antigen-presenting cells: can anything replace a dendritic cell?
    • Kambayashi, T., Laufer, T.M., Atypical MHC class II-expressing antigen-presenting cells: can anything replace a dendritic cell?. Nat Rev Immunol 14:11 (2014), 719–730.
    • (2014) Nat Rev Immunol , vol.14 , Issue.11 , pp. 719-730
    • Kambayashi, T.1    Laufer, T.M.2
  • 84
    • 84873423706 scopus 로고    scopus 로고
    • Concise review: acute graft-versus-host disease: immunobiology, prevention, and treatment
    • Sung, A.D., Chao, N.J., Concise review: acute graft-versus-host disease: immunobiology, prevention, and treatment. Stem Cells Transl Med 2:1 (2013), 25–32.
    • (2013) Stem Cells Transl Med , vol.2 , Issue.1 , pp. 25-32
    • Sung, A.D.1    Chao, N.J.2
  • 87
    • 70350598047 scopus 로고    scopus 로고
    • Dichotomous role of interferon-gamma in allogeneic bone marrow transplant
    • Lu, Y., Waller, E.K., Dichotomous role of interferon-gamma in allogeneic bone marrow transplant. Biol Blood Marrow Transplant 15:11 (2009), 1347–1353.
    • (2009) Biol Blood Marrow Transplant , vol.15 , Issue.11 , pp. 1347-1353
    • Lu, Y.1    Waller, E.K.2
  • 89
    • 0034193057 scopus 로고    scopus 로고
    • The primacy of the gastrointestinal tract as a target organ of acute graft-versus-host disease: rationale for the use of cytokine shields in allogeneic bone marrow transplantation
    • Hill, G.R., Ferrara, J.L., The primacy of the gastrointestinal tract as a target organ of acute graft-versus-host disease: rationale for the use of cytokine shields in allogeneic bone marrow transplantation. Blood 95:9 (2000), 2754–2759.
    • (2000) Blood , vol.95 , Issue.9 , pp. 2754-2759
    • Hill, G.R.1    Ferrara, J.L.2
  • 90
    • 0031725838 scopus 로고    scopus 로고
    • High-level IL-12 production by human dendritic cells requires two signals
    • Snijders, A., Kalinski, P., Hilkens, C.M., Kapsenberg, M.L., High-level IL-12 production by human dendritic cells requires two signals. Int Immunol 10:11 (1998), 1593–1598.
    • (1998) Int Immunol , vol.10 , Issue.11 , pp. 1593-1598
    • Snijders, A.1    Kalinski, P.2    Hilkens, C.M.3    Kapsenberg, M.L.4
  • 91
    • 84893541095 scopus 로고    scopus 로고
    • The complex and central role of interferon-gamma in graft-versus-host disease and graft-versus-tumor activity
    • Wang, H., Yang, Y.G., The complex and central role of interferon-gamma in graft-versus-host disease and graft-versus-tumor activity. Immunol Rev 258:1 (2014), 30–44.
    • (2014) Immunol Rev , vol.258 , Issue.1 , pp. 30-44
    • Wang, H.1    Yang, Y.G.2
  • 92
    • 33846000279 scopus 로고    scopus 로고
    • Transplantation's greatest challenges: advances in chronic graft-versus-host disease
    • Shlomchik, W.D., Lee, S.J., Couriel, D., Pavletic, S.Z., Transplantation's greatest challenges: advances in chronic graft-versus-host disease. Biol Blood Marrow Transplant 13:Suppl. 1 (2007), 2–10.
    • (2007) Biol Blood Marrow Transplant , vol.13 , pp. 2-10
    • Shlomchik, W.D.1    Lee, S.J.2    Couriel, D.3    Pavletic, S.Z.4
  • 93
    • 79953123445 scopus 로고    scopus 로고
    • Effector CD4+ T cells, the cytokines they generate, and GVHD: something old and something new
    • Coghill, J.M., Sarantopoulos, S., Moran, T.P., Murphy, W.J., Blazar, B.R., Serody, J.S., Effector CD4+ T cells, the cytokines they generate, and GVHD: something old and something new. Blood 117:12 (2011), 3268–3276.
    • (2011) Blood , vol.117 , Issue.12 , pp. 3268-3276
    • Coghill, J.M.1    Sarantopoulos, S.2    Moran, T.P.3    Murphy, W.J.4    Blazar, B.R.5    Serody, J.S.6
  • 94
    • 84961821081 scopus 로고    scopus 로고
    • Donor interleukin-22 and host type I interferon signaling pathway participate in intestinal graft-versus-host disease via STAT1 activation and CXCL10
    • Lamarthee, B., Malard, F., Gamonet, C., Bossard, C., Couturier, M., Renauld, J.C., Mohty, M., Saas, P., Gaugler, B., Donor interleukin-22 and host type I interferon signaling pathway participate in intestinal graft-versus-host disease via STAT1 activation and CXCL10. Mucosal Immunol 9:2 (2016), 309–321.
    • (2016) Mucosal Immunol , vol.9 , Issue.2 , pp. 309-321
    • Lamarthee, B.1    Malard, F.2    Gamonet, C.3    Bossard, C.4    Couturier, M.5    Renauld, J.C.6    Mohty, M.7    Saas, P.8    Gaugler, B.9
  • 95
    • 85014917342 scopus 로고    scopus 로고
    • Chronic graft-versus-host disease: biological insights from preclinical and clinical studies
    • MacDonald, K.P., Hill, G.R., Blazar, B.R., Chronic graft-versus-host disease: biological insights from preclinical and clinical studies. Blood 129:1 (2017), 13–21.
    • (2017) Blood , vol.129 , Issue.1 , pp. 13-21
    • MacDonald, K.P.1    Hill, G.R.2    Blazar, B.R.3
  • 97
    • 0038466071 scopus 로고    scopus 로고
    • The role of interferon-gamma, nitric oxide and lipopolysaccharide in intestinal graft-versus-host disease developing in F1-hybrid mice
    • Ellison, C.A., Natuik, S.A., McIntosh, A.R., Scully, S.A., Danilenko, D.M., Gartner, J.G., The role of interferon-gamma, nitric oxide and lipopolysaccharide in intestinal graft-versus-host disease developing in F1-hybrid mice. Immunology 109:3 (2003), 440–449.
    • (2003) Immunology , vol.109 , Issue.3 , pp. 440-449
    • Ellison, C.A.1    Natuik, S.A.2    McIntosh, A.R.3    Scully, S.A.4    Danilenko, D.M.5    Gartner, J.G.6
  • 98
    • 72549089070 scopus 로고    scopus 로고
    • IFN-gamma triggered STAT1-PKB/AKT signalling pathway influences the function of alloantigen reactive regulatory T cells
    • Wei, B., Baker, S., Wieckiewicz, J., Wood, K.J., IFN-gamma triggered STAT1-PKB/AKT signalling pathway influences the function of alloantigen reactive regulatory T cells. Am J Transplant 10:1 (2010), 69–80.
    • (2010) Am J Transplant , vol.10 , Issue.1 , pp. 69-80
    • Wei, B.1    Baker, S.2    Wieckiewicz, J.3    Wood, K.J.4
  • 99
    • 84863061015 scopus 로고    scopus 로고
    • IFN-gamma and indoleamine 2,3-dioxygenase signaling between donor dendritic cells and T cells regulates graft versus host and graft versus leukemia activity
    • Lu, Y., Giver, C.R., Sharma, A., Li, J.M., Darlak, K.A., Owens, L.M., Roback, J.D., Galipeau, J., Waller, E.K., IFN-gamma and indoleamine 2,3-dioxygenase signaling between donor dendritic cells and T cells regulates graft versus host and graft versus leukemia activity. Blood 119:4 (2012), 1075–1085.
    • (2012) Blood , vol.119 , Issue.4 , pp. 1075-1085
    • Lu, Y.1    Giver, C.R.2    Sharma, A.3    Li, J.M.4    Darlak, K.A.5    Owens, L.M.6    Roback, J.D.7    Galipeau, J.8    Waller, E.K.9
  • 100
    • 0024431496 scopus 로고
    • Prediction of graft versus host disease by frequency analysis of cytotoxic T cells after unrelated donor bone marrow transplantation
    • Kaminski, E., Hows, J., Man, S., Brookes, P., Mackinnon, S., Hughes, T., Avakian, O., Goldman, J.M., Batchelor, J.R., Prediction of graft versus host disease by frequency analysis of cytotoxic T cells after unrelated donor bone marrow transplantation. Transplantation 48:4 (1989), 608–613.
    • (1989) Transplantation , vol.48 , Issue.4 , pp. 608-613
    • Kaminski, E.1    Hows, J.2    Man, S.3    Brookes, P.4    Mackinnon, S.5    Hughes, T.6    Avakian, O.7    Goldman, J.M.8    Batchelor, J.R.9
  • 101
    • 0036732722 scopus 로고    scopus 로고
    • Cross-primed CD8(+) T cells mediate graft rejection via a distinct effector pathway
    • Valujskikh, A., Lantz, O., Celli, S., Matzinger, P., Heeger, P.S., Cross-primed CD8(+) T cells mediate graft rejection via a distinct effector pathway. Nat Immunol 3:9 (2002), 844–851.
    • (2002) Nat Immunol , vol.3 , Issue.9 , pp. 844-851
    • Valujskikh, A.1    Lantz, O.2    Celli, S.3    Matzinger, P.4    Heeger, P.S.5
  • 102
    • 33846018568 scopus 로고    scopus 로고
    • An essential role for IFN-gamma in regulation of alloreactive CD8 T cells following allogeneic hematopoietic cell transplantation
    • Asavaroengchai, W., Wang, H., Wang, S., Wang, L., Bronson, R., Sykes, M., Yang, Y.G., An essential role for IFN-gamma in regulation of alloreactive CD8 T cells following allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant 13:1 (2007), 46–55.
    • (2007) Biol Blood Marrow Transplant , vol.13 , Issue.1 , pp. 46-55
    • Asavaroengchai, W.1    Wang, H.2    Wang, S.3    Wang, L.4    Bronson, R.5    Sykes, M.6    Yang, Y.G.7
  • 103
    • 80053329222 scopus 로고    scopus 로고
    • Cell therapy with autologous tolerogenic dendritic cells induces allograft tolerance through interferon-gamma and epstein-barr virus-induced gene 3
    • Hill, M., Thebault, P., Segovia, M., Louvet, C., Beriou, G., Tilly, G., Merieau, E., Anegon, I., Chiffoleau, E., Cuturi, M.C., Cell therapy with autologous tolerogenic dendritic cells induces allograft tolerance through interferon-gamma and epstein-barr virus-induced gene 3. Am J Transplant 11:10 (2011), 2036–2045.
    • (2011) Am J Transplant , vol.11 , Issue.10 , pp. 2036-2045
    • Hill, M.1    Thebault, P.2    Segovia, M.3    Louvet, C.4    Beriou, G.5    Tilly, G.6    Merieau, E.7    Anegon, I.8    Chiffoleau, E.9    Cuturi, M.C.10
  • 104
    • 0036624924 scopus 로고    scopus 로고
    • Donor-derived interferon gamma separates graft-versus-leukemia effects and graft-versus-host disease induced by donor CD8 T cells
    • Yang, Y.G., Qi, J., Wang, M.G., Sykes, M., Donor-derived interferon gamma separates graft-versus-leukemia effects and graft-versus-host disease induced by donor CD8 T cells. Blood 99:11 (2002), 4207–4215.
    • (2002) Blood , vol.99 , Issue.11 , pp. 4207-4215
    • Yang, Y.G.1    Qi, J.2    Wang, M.G.3    Sykes, M.4
  • 105
    • 0034601012 scopus 로고    scopus 로고
    • Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis
    • Chu, C.Q., Wittmer, S., Dalton, D.K., Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis. J Exp Med 192:1 (2000), 123–128.
    • (2000) J Exp Med , vol.192 , Issue.1 , pp. 123-128
    • Chu, C.Q.1    Wittmer, S.2    Dalton, D.K.3
  • 106
    • 0034600788 scopus 로고    scopus 로고
    • Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells
    • Dalton, D.K., Haynes, L., Chu, C.Q., Swain, S.L., Wittmer, S., Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells. J Exp Med 192:1 (2000), 117–122.
    • (2000) J Exp Med , vol.192 , Issue.1 , pp. 117-122
    • Dalton, D.K.1    Haynes, L.2    Chu, C.Q.3    Swain, S.L.4    Wittmer, S.5
  • 107
    • 0034680811 scopus 로고    scopus 로고
    • Regulation of antigen-specific CD8+ T cell homeostasis by perforin and interferon-gamma
    • Badovinac, V.P., Tvinnereim, A.R., Harty, J.T., Regulation of antigen-specific CD8+ T cell homeostasis by perforin and interferon-gamma. Science 290:5495 (2000), 1354–1358.
    • (2000) Science , vol.290 , Issue.5495 , pp. 1354-1358
    • Badovinac, V.P.1    Tvinnereim, A.R.2    Harty, J.T.3
  • 108
    • 0031179124 scopus 로고    scopus 로고
    • Expression and role in apoptosis of the alpha- and beta-chains of the IFN-gamma receptor on human Th1 and Th2 clones
    • Novelli, F., D'Elios, M.M., Bernabei, P., Ozmen, L., Rigamonti, L., Almerigogna, F., Forni, G., Del Prete, G., Expression and role in apoptosis of the alpha- and beta-chains of the IFN-gamma receptor on human Th1 and Th2 clones. J Immunol 159:1 (1997), 206–213.
    • (1997) J Immunol , vol.159 , Issue.1 , pp. 206-213
    • Novelli, F.1    D'Elios, M.M.2    Bernabei, P.3    Ozmen, L.4    Rigamonti, L.5    Almerigogna, F.6    Forni, G.7    Del Prete, G.8
  • 109
    • 0037037582 scopus 로고    scopus 로고
    • Interferon gamma is required for activation-induced death of T lymphocytes
    • Refaeli, Y., Parijs, L. Van, Alexander, S.I., Abbas, A.K., Interferon gamma is required for activation-induced death of T lymphocytes. J Exp Med 196:7 (2002), 999–1005.
    • (2002) J Exp Med , vol.196 , Issue.7 , pp. 999-1005
    • Refaeli, Y.1    Parijs, L.V.2    Alexander, S.I.3    Abbas, A.K.4
  • 110
    • 0032031409 scopus 로고    scopus 로고
    • IFN-gamma is critical for long-term allograft survival induced by blocking the CD28 and CD40 ligand T cell costimulation pathways
    • Konieczny, B.T., Dai, Z., Elwood, E.T., Saleem, S., Linsley, P.S., Baddoura, F.K., Larsen, C.P., Pearson, T.C., Lakkis, F.G., IFN-gamma is critical for long-term allograft survival induced by blocking the CD28 and CD40 ligand T cell costimulation pathways. J Immunol 160:5 (1998), 2059–2064.
    • (1998) J Immunol , vol.160 , Issue.5 , pp. 2059-2064
    • Konieczny, B.T.1    Dai, Z.2    Elwood, E.T.3    Saleem, S.4    Linsley, P.S.5    Baddoura, F.K.6    Larsen, C.P.7    Pearson, T.C.8    Lakkis, F.G.9
  • 112
    • 8344246987 scopus 로고    scopus 로고
    • Suppressed T-cell activation by IFN-gamma-induced expression of PD-L1 on renal tubular epithelial cells
    • Schoop, R., Wahl, P., Le Hir, M., Heemann, U., Wang, M., Wuthrich, R.P., Suppressed T-cell activation by IFN-gamma-induced expression of PD-L1 on renal tubular epithelial cells. Nephrol Dial Transplant 19:11 (2004), 2713–2720.
    • (2004) Nephrol Dial Transplant , vol.19 , Issue.11 , pp. 2713-2720
    • Schoop, R.1    Wahl, P.2    Le Hir, M.3    Heemann, U.4    Wang, M.5    Wuthrich, R.P.6
  • 114
    • 0041845131 scopus 로고    scopus 로고
    • Blockade of programmed death-1 engagement accelerates graft-versus-host disease lethality by an IFN-gamma-dependent mechanism
    • Blazar, B.R., Carreno, B.M., Panoskaltsis-Mortari, A., Carter, L., Iwai, Y., Yagita, H., Nishimura, H., Taylor, P.A., Blockade of programmed death-1 engagement accelerates graft-versus-host disease lethality by an IFN-gamma-dependent mechanism. J Immunol 171:3 (2003), 1272–1277.
    • (2003) J Immunol , vol.171 , Issue.3 , pp. 1272-1277
    • Blazar, B.R.1    Carreno, B.M.2    Panoskaltsis-Mortari, A.3    Carter, L.4    Iwai, Y.5    Yagita, H.6    Nishimura, H.7    Taylor, P.A.8
  • 115
    • 33746176176 scopus 로고    scopus 로고
    • Fontolizumab, a humanised anti-interferon gamma antibody, demonstrates safety and clinical activity in patients with moderate to severe Crohn's disease
    • Hommes, D.W., Mikhajlova, T.L., Stoinov, S., Stimac, D., Vucelic, B., Lonovics, J., Zakuciova, M., D'Haens, G., Van Assche, G., Ba, S., Lee, S., Pearce, T., Fontolizumab, a humanised anti-interferon gamma antibody, demonstrates safety and clinical activity in patients with moderate to severe Crohn's disease. Gut 55:8 (2006), 1131–1137.
    • (2006) Gut , vol.55 , Issue.8 , pp. 1131-1137
    • Hommes, D.W.1    Mikhajlova, T.L.2    Stoinov, S.3    Stimac, D.4    Vucelic, B.5    Lonovics, J.6    Zakuciova, M.7    D'Haens, G.8    Van Assche, G.9    Ba, S.10    Lee, S.11    Pearce, T.12
  • 116
    • 33746132472 scopus 로고    scopus 로고
    • A dose escalating, placebo controlled, double blind, single dose and multidose, safety and tolerability study of fontolizumab, a humanised anti-interferon gamma antibody, in patients with moderate to severe Crohn's disease
    • Reinisch, W., Hommes, D.W., Van Assche, G., Colombel, J.F., Gendre, J.P., Oldenburg, B., Teml, A., Geboes, K., Ding, H., Zhang, L., Tang, M., Cheng, M., van Deventer, S.J., Rutgeerts, P., Pearce, T., A dose escalating, placebo controlled, double blind, single dose and multidose, safety and tolerability study of fontolizumab, a humanised anti-interferon gamma antibody, in patients with moderate to severe Crohn's disease. Gut 55:8 (2006), 1138–1144.
    • (2006) Gut , vol.55 , Issue.8 , pp. 1138-1144
    • Reinisch, W.1    Hommes, D.W.2    Van Assche, G.3    Colombel, J.F.4    Gendre, J.P.5    Oldenburg, B.6    Teml, A.7    Geboes, K.8    Ding, H.9    Zhang, L.10    Tang, M.11    Cheng, M.12    van Deventer, S.J.13    Rutgeerts, P.14    Pearce, T.15
  • 117
    • 0034881151 scopus 로고    scopus 로고
    • Randomized, double-blind trial of anti-interferon-gamma antibodies in rheumatoid arthritis
    • Sigidin, Y.A., Loukina, G.V., Skurkovich, B., Skurkovich, S., Randomized, double-blind trial of anti-interferon-gamma antibodies in rheumatoid arthritis. Scand J Rheumatol 30:4 (2001), 203–207.
    • (2001) Scand J Rheumatol , vol.30 , Issue.4 , pp. 203-207
    • Sigidin, Y.A.1    Loukina, G.V.2    Skurkovich, B.3    Skurkovich, S.4
  • 118
    • 0034129549 scopus 로고    scopus 로고
    • Clinical improvement and immunohistochemical findings in severe atopic dermatitis treated with interferon gamma
    • Jang, I.G., Yang, J.K., Lee, H.J., Yi, J.Y., Kim, H.O., Kim, C.W., Kim, T.Y., Clinical improvement and immunohistochemical findings in severe atopic dermatitis treated with interferon gamma. J Am Acad Dermatol 42:6 (2000), 1033–1040.
    • (2000) J Am Acad Dermatol , vol.42 , Issue.6 , pp. 1033-1040
    • Jang, I.G.1    Yang, J.K.2    Lee, H.J.3    Yi, J.Y.4    Kim, H.O.5    Kim, C.W.6    Kim, T.Y.7
  • 119
    • 0026767264 scopus 로고
    • Recombinant human interferon gamma in the treatment of rheumatoid arthritis: double blind placebo controlled study
    • Machold, K.P., Neumann, K., Smolen, J.S., Recombinant human interferon gamma in the treatment of rheumatoid arthritis: double blind placebo controlled study. Ann Rheum Dis 51:9 (1992), 1039–1043.
    • (1992) Ann Rheum Dis , vol.51 , Issue.9 , pp. 1039-1043
    • Machold, K.P.1    Neumann, K.2    Smolen, J.S.3
  • 121
    • 0023914840 scopus 로고
    • Results of a multicenter placebo-controlled double-blind randomized phase III clinical study of treatment of rheumatoid arthritis with recombinant interferon-gamma
    • Lemmel, E.M., Brackertz, D., Franke, M., Gaus, W., Hartl, P.W., Machalke, K., Mielke, H., Obert, H.J., Peter, H.H., Sieper, J., et al. Results of a multicenter placebo-controlled double-blind randomized phase III clinical study of treatment of rheumatoid arthritis with recombinant interferon-gamma. Rheumatol Int 8:2 (1988), 87–93.
    • (1988) Rheumatol Int , vol.8 , Issue.2 , pp. 87-93
    • Lemmel, E.M.1    Brackertz, D.2    Franke, M.3    Gaus, W.4    Hartl, P.W.5    Machalke, K.6    Mielke, H.7    Obert, H.J.8    Peter, H.H.9    Sieper, J.10
  • 123
    • 84876406357 scopus 로고    scopus 로고
    • Possible roles of IL-12-family cytokines in rheumatoid arthritis
    • Pope, R.M., Shahrara, S., Possible roles of IL-12-family cytokines in rheumatoid arthritis. Nat Rev Rheumatol 9:4 (2013), 252–256.
    • (2013) Nat Rev Rheumatol , vol.9 , Issue.4 , pp. 252-256
    • Pope, R.M.1    Shahrara, S.2
  • 124
    • 23844487193 scopus 로고    scopus 로고
    • Expression of mouse HtrA1 serine protease in normal bone and cartilage and its upregulation in joint cartilage damaged by experimental arthritis
    • Tsuchiya, A., Yano, M., Tocharus, J., Kojima, H., Fukumoto, M., Kawaichi, M., Oka, C., Expression of mouse HtrA1 serine protease in normal bone and cartilage and its upregulation in joint cartilage damaged by experimental arthritis. Bone 37:3 (2005), 323–336.
    • (2005) Bone , vol.37 , Issue.3 , pp. 323-336
    • Tsuchiya, A.1    Yano, M.2    Tocharus, J.3    Kojima, H.4    Fukumoto, M.5    Kawaichi, M.6    Oka, C.7
  • 125
    • 77953031568 scopus 로고    scopus 로고
    • Role of HTRA1, a serine protease, in the progression of articular cartilage degeneration
    • Polur, I., Lee, P.L., Servais, J.M., Xu, L., Li, Y., Role of HTRA1, a serine protease, in the progression of articular cartilage degeneration. Histol Histopathol 25:5 (2010), 599–608.
    • (2010) Histol Histopathol , vol.25 , Issue.5 , pp. 599-608
    • Polur, I.1    Lee, P.L.2    Servais, J.M.3    Xu, L.4    Li, Y.5
  • 127
    • 0032545407 scopus 로고    scopus 로고
    • Human HtrA, an evolutionarily conserved serine protease identified as a differentially expressed gene product in osteoarthritic cartilage
    • Hu, S.I., Carozza, M., Klein, M., Nantermet, P., Luk, D., Crowl, R.M., Human HtrA, an evolutionarily conserved serine protease identified as a differentially expressed gene product in osteoarthritic cartilage. J Biol Chem 273:51 (1998), 34406–34412.
    • (1998) J Biol Chem , vol.273 , Issue.51 , pp. 34406-34412
    • Hu, S.I.1    Carozza, M.2    Klein, M.3    Nantermet, P.4    Luk, D.5    Crowl, R.M.6
  • 129
    • 84928728998 scopus 로고    scopus 로고
    • Interferon gene expression signature in rheumatoid arthritis neutrophils correlates with a good response to TNFi therapy
    • Wright, H.L., Thomas, H.B., Moots, R.J., Edwards, S.W., Interferon gene expression signature in rheumatoid arthritis neutrophils correlates with a good response to TNFi therapy. Rheumatology (Oxford) 54:1 (2015), 188–193.
    • (2015) Rheumatology (Oxford) , vol.54 , Issue.1 , pp. 188-193
    • Wright, H.L.1    Thomas, H.B.2    Moots, R.J.3    Edwards, S.W.4
  • 130
    • 0023126661 scopus 로고
    • Exacerbations of multiple sclerosis in patients treated with gamma interferon
    • Panitch, H.S., Hirsch, R.L., Haley, A.S., Johnson, K.P., Exacerbations of multiple sclerosis in patients treated with gamma interferon. Lancet 1:8538 (1987), 893–895.
    • (1987) Lancet , vol.1 , Issue.8538 , pp. 893-895
    • Panitch, H.S.1    Hirsch, R.L.2    Haley, A.S.3    Johnson, K.P.4
  • 131
    • 84938305062 scopus 로고    scopus 로고
    • Anti-inflammatory mechanisms of IFN-gamma studied in experimental autoimmune encephalomyelitis reveal neutrophils as a potential target in multiple sclerosis
    • Miller, N.M., Wang, J., Tan, Y., Dittel, B.N., Anti-inflammatory mechanisms of IFN-gamma studied in experimental autoimmune encephalomyelitis reveal neutrophils as a potential target in multiple sclerosis. Front Neurosci, 9, 2015, 287.
    • (2015) Front Neurosci , vol.9 , pp. 287
    • Miller, N.M.1    Wang, J.2    Tan, Y.3    Dittel, B.N.4
  • 132
    • 0026055348 scopus 로고
    • Gamma-interferon induction in patients with chronic progressive MS
    • Bever, C.T. Jr., Panitch, H.S., Levy, H.B., McFarlin, D.E., Johnson, K.P., Gamma-interferon induction in patients with chronic progressive MS. Neurology 41:7 (1991), 1124–1127.
    • (1991) Neurology , vol.41 , Issue.7 , pp. 1124-1127
    • Bever, C.T.1    Panitch, H.S.2    Levy, H.B.3    McFarlin, D.E.4    Johnson, K.P.5
  • 133
    • 84860719963 scopus 로고    scopus 로고
    • Discrepant effects of human interferon-gamma on clinical and immunological disease parameters in a novel marmoset model for multiple sclerosis
    • Jagessar, S.A., Gran, B., Heijmans, N., Bauer, J., Laman, J.D., t Hart, B.A., Constantinescu, C.S., Discrepant effects of human interferon-gamma on clinical and immunological disease parameters in a novel marmoset model for multiple sclerosis. J Neuroimmune Pharmacol 7:1 (2012), 253–265.
    • (2012) J Neuroimmune Pharmacol , vol.7 , Issue.1 , pp. 253-265
    • Jagessar, S.A.1    Gran, B.2    Heijmans, N.3    Bauer, J.4    Laman, J.D.5    t Hart, B.A.6    Constantinescu, C.S.7
  • 134
    • 33750628439 scopus 로고    scopus 로고
    • Current concepts in the pathophysiology and treatment of aplastic anemia
    • Young, N.S., Calado, R.T., Scheinberg, P., Current concepts in the pathophysiology and treatment of aplastic anemia. Blood 108:8 (2006), 2509–2519.
    • (2006) Blood , vol.108 , Issue.8 , pp. 2509-2519
    • Young, N.S.1    Calado, R.T.2    Scheinberg, P.3
  • 136
    • 84865422362 scopus 로고    scopus 로고
    • Intrinsic impairment of CD4(+)CD25(+) regulatory T cells in acquired aplastic anemia
    • Shi, J., Ge, M., Lu, S., Li, X., Shao, Y., Huang, J., Huang, Z., Zhang, J., Nie, N., Zheng, Y., Intrinsic impairment of CD4(+)CD25(+) regulatory T cells in acquired aplastic anemia. Blood 120:8 (2012), 1624–1632.
    • (2012) Blood , vol.120 , Issue.8 , pp. 1624-1632
    • Shi, J.1    Ge, M.2    Lu, S.3    Li, X.4    Shao, Y.5    Huang, J.6    Huang, Z.7    Zhang, J.8    Nie, N.9    Zheng, Y.10
  • 137
    • 0037441586 scopus 로고    scopus 로고
    • Aplastic Anemia Study, Antithymocyte globulin with or without cyclosporin A: 11-year follow-up of a randomized trial comparing treatments of aplastic anemia
    • Frickhofen, N., Heimpel, H., Kaltwasser, J.P., Schrezenmeier, H., German, G., Aplastic Anemia Study, Antithymocyte globulin with or without cyclosporin A: 11-year follow-up of a randomized trial comparing treatments of aplastic anemia. Blood 101:4 (2003), 1236–1242.
    • (2003) Blood , vol.101 , Issue.4 , pp. 1236-1242
    • Frickhofen, N.1    Heimpel, H.2    Kaltwasser, J.P.3    Schrezenmeier, H.4    German, G.5
  • 138
    • 0029016931 scopus 로고
    • Fas antigen expression on CD34+ human marrow cells is induced by interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro
    • Maciejewski, J., Selleri, C., Anderson, S., Young, N.S., Fas antigen expression on CD34+ human marrow cells is induced by interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro. Blood 85:11 (1995), 3183–3190.
    • (1995) Blood , vol.85 , Issue.11 , pp. 3183-3190
    • Maciejewski, J.1    Selleri, C.2    Anderson, S.3    Young, N.S.4
  • 139
    • 0019961448 scopus 로고
    • Gamma interferon (IFN gamma) and IFN alpha/beta suppress murine myeloid colony formation (CFU-C)N: magnitude of suppression is dependent upon level of colony-stimulating factor (CSF)
    • Klimpel, G.R., Fleischmann, W.R. Jr., Klimpel, K.D., Gamma interferon (IFN gamma) and IFN alpha/beta suppress murine myeloid colony formation (CFU-C)N: magnitude of suppression is dependent upon level of colony-stimulating factor (CSF). J Immunol 129:1 (1982), 76–80.
    • (1982) J Immunol , vol.129 , Issue.1 , pp. 76-80
    • Klimpel, G.R.1    Fleischmann, W.R.2    Klimpel, K.D.3
  • 140
    • 0021240611 scopus 로고
    • Interferon is the suppressor of hematopoiesis generated by stimulated lymphocytes in vitro
    • Zoumbos, N.C., Djeu, J.Y., Young, N.S., Interferon is the suppressor of hematopoiesis generated by stimulated lymphocytes in vitro. J Immunol 133:2 (1984), 769–774.
    • (1984) J Immunol , vol.133 , Issue.2 , pp. 769-774
    • Zoumbos, N.C.1    Djeu, J.Y.2    Young, N.S.3
  • 141
    • 0028070910 scopus 로고
    • Interferon gamma selectively inhibits very primitive CD342+CD38- and not more mature CD34+CD38+ human hematopoietic progenitor cells
    • Snoeck, H.W., Van Bockstaele, D.R., Nys, G., Lenjou, M., Lardon, F., Haenen, L., Rodrigus, I., Peetermans, M.E., Berneman, Z.N., Interferon gamma selectively inhibits very primitive CD342+CD38- and not more mature CD34+CD38+ human hematopoietic progenitor cells. J Exp Med 180:3 (1994), 1177–1182.
    • (1994) J Exp Med , vol.180 , Issue.3 , pp. 1177-1182
    • Snoeck, H.W.1    Van Bockstaele, D.R.2    Nys, G.3    Lenjou, M.4    Lardon, F.5    Haenen, L.6    Rodrigus, I.7    Peetermans, M.E.8    Berneman, Z.N.9
  • 142
    • 0029990271 scopus 로고    scopus 로고
    • Interferon-gamma constitutively expressed in the stromal microenvironment of human marrow cultures mediates potent hematopoietic inhibition
    • Selleri, C., Maciejewski, J.P., Sato, T., Young, N.S., Interferon-gamma constitutively expressed in the stromal microenvironment of human marrow cultures mediates potent hematopoietic inhibition. Blood 87:10 (1996), 4149–4157.
    • (1996) Blood , vol.87 , Issue.10 , pp. 4149-4157
    • Selleri, C.1    Maciejewski, J.P.2    Sato, T.3    Young, N.S.4
  • 143
    • 84908137383 scopus 로고    scopus 로고
    • Impact of interferon-gamma on hematopoiesis
    • de Bruin, A.M., Voermans, C., Nolte, M.A., Impact of interferon-gamma on hematopoiesis. Blood 124:16 (2014), 2479–2486.
    • (2014) Blood , vol.124 , Issue.16 , pp. 2479-2486
    • de Bruin, A.M.1    Voermans, C.2    Nolte, M.A.3
  • 144
    • 79957564919 scopus 로고    scopus 로고
    • Interleukin-27 enhances the production of tumour necrosis factor-alpha and interferon-gamma by bone marrow T lymphocytes in aplastic anaemia
    • Li, J., Zhao, Q., Xing, W., Feng, J., Wu, H., Li, H., Ge, M., Tian, K., Li, X., Zhou, J., Liu, B., Zhang, L., Zheng, Y., Han, Z.C., Interleukin-27 enhances the production of tumour necrosis factor-alpha and interferon-gamma by bone marrow T lymphocytes in aplastic anaemia. Br J Haematol 153:6 (2011), 764–772.
    • (2011) Br J Haematol , vol.153 , Issue.6 , pp. 764-772
    • Li, J.1    Zhao, Q.2    Xing, W.3    Feng, J.4    Wu, H.5    Li, H.6    Ge, M.7    Tian, K.8    Li, X.9    Zhou, J.10    Liu, B.11    Zhang, L.12    Zheng, Y.13    Han, Z.C.14
  • 147
    • 84951310757 scopus 로고    scopus 로고
    • NK cells and cancer: you can teach innate cells new tricks
    • Morvan, M.G., Lanier, L.L., NK cells and cancer: you can teach innate cells new tricks. Nat Rev Cancer 16:1 (2016), 7–19.
    • (2016) Nat Rev Cancer , vol.16 , Issue.1 , pp. 7-19
    • Morvan, M.G.1    Lanier, L.L.2
  • 148
    • 84858784892 scopus 로고    scopus 로고
    • Targeting natural killer cells and natural killer T cells in cancer
    • Vivier, E., Ugolini, S., Blaise, D., Chabannon, C., Brossay, L., Targeting natural killer cells and natural killer T cells in cancer. Nat Rev Immunol 12:4 (2012), 239–252.
    • (2012) Nat Rev Immunol , vol.12 , Issue.4 , pp. 239-252
    • Vivier, E.1    Ugolini, S.2    Blaise, D.3    Chabannon, C.4    Brossay, L.5
  • 150
    • 80053469514 scopus 로고    scopus 로고
    • The two faces of interferon-gamma in cancer
    • Zaidi, M.R., Merlino, G., The two faces of interferon-gamma in cancer. Clin Cancer Res 17:19 (2011), 6118–6124.
    • (2011) Clin Cancer Res , vol.17 , Issue.19 , pp. 6118-6124
    • Zaidi, M.R.1    Merlino, G.2
  • 152
    • 84941711371 scopus 로고    scopus 로고
    • Anti-PD-1/PD-L1 therapy of human cancer: past, present, and future
    • Chen, L., Han, X., Anti-PD-1/PD-L1 therapy of human cancer: past, present, and future. J Clin Invest 125:9 (2015), 3384–3391.
    • (2015) J Clin Invest , vol.125 , Issue.9 , pp. 3384-3391
    • Chen, L.1    Han, X.2
  • 154
    • 85026905943 scopus 로고    scopus 로고
    • PD-L1 induced by IFN-gamma from tumor-associated macrophages via the JAK/STAT3 and PI3K/AKT signaling pathways promoted progression of lung cancer
    • Zhang, X., Zeng, Y., Qu, Q., Zhu, J., Liu, Z., Ning, W., Zeng, H., Zhang, N., Du, W., Chen, C., Huang, J.A., PD-L1 induced by IFN-gamma from tumor-associated macrophages via the JAK/STAT3 and PI3K/AKT signaling pathways promoted progression of lung cancer. Int J Clin Oncol 22:6 (2017), 1026–1033.
    • (2017) Int J Clin Oncol , vol.22 , Issue.6 , pp. 1026-1033
    • Zhang, X.1    Zeng, Y.2    Qu, Q.3    Zhu, J.4    Liu, Z.5    Ning, W.6    Zeng, H.7    Zhang, N.8    Du, W.9    Chen, C.10    Huang, J.A.11
  • 155
    • 84868220730 scopus 로고    scopus 로고
    • Tryptophan catabolism in cancer: beyond IDO and tryptophan depletion
    • Platten, M., Wick, W., Van den Eynde, B.J., Tryptophan catabolism in cancer: beyond IDO and tryptophan depletion. Cancer Res 72:21 (2012), 5435–5440.
    • (2012) Cancer Res , vol.72 , Issue.21 , pp. 5435-5440
    • Platten, M.1    Wick, W.2    Van den Eynde, B.J.3
  • 156
    • 84920822820 scopus 로고    scopus 로고
    • Amino acids and immune response: a role for cysteine, glutamine, phenylalanine, tryptophan and arginine in T-cell function and cancer?
    • Sikalidis, A.K., Amino acids and immune response: a role for cysteine, glutamine, phenylalanine, tryptophan and arginine in T-cell function and cancer?. Pathol Oncol Res 21:1 (2015), 9–17.
    • (2015) Pathol Oncol Res , vol.21 , Issue.1 , pp. 9-17
    • Sikalidis, A.K.1
  • 157
    • 84906937205 scopus 로고    scopus 로고
    • Mechanisms of disseminated cancer cell dormancy: an awakening field
    • Sosa, M.S., Bragado, P., Aguirre-Ghiso, J.A., Mechanisms of disseminated cancer cell dormancy: an awakening field. Nat Rev Cancer 14:9 (2014), 611–622.
    • (2014) Nat Rev Cancer , vol.14 , Issue.9 , pp. 611-622
    • Sosa, M.S.1    Bragado, P.2    Aguirre-Ghiso, J.A.3
  • 161
    • 2342559752 scopus 로고    scopus 로고
    • HLA-G1-expressing antigen-presenting cells induce immunosuppressive CD4+ T cells
    • LeMaoult, J., Krawice-Radanne, I., Dausset, J., Carosella, E.D., HLA-G1-expressing antigen-presenting cells induce immunosuppressive CD4+ T cells. Proc Natl Acad Sci U S A 101:18 (2004), 7064–7069.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.18 , pp. 7064-7069
    • LeMaoult, J.1    Krawice-Radanne, I.2    Dausset, J.3    Carosella, E.D.4
  • 162
    • 0042209924 scopus 로고    scopus 로고
    • Soluble HLA-G inhibits human dendritic cell-triggered allogeneic T-cell proliferation without altering dendritic differentiation and maturation processes
    • Le Friec, G., Laupeze, B., Fardel, O., Sebti, Y., Pangault, C., Guilloux, V., Beauplet, A., Fauchet, R., Amiot, L., Soluble HLA-G inhibits human dendritic cell-triggered allogeneic T-cell proliferation without altering dendritic differentiation and maturation processes. Hum Immunol 64:8 (2003), 752–761.
    • (2003) Hum Immunol , vol.64 , Issue.8 , pp. 752-761
    • Le Friec, G.1    Laupeze, B.2    Fardel, O.3    Sebti, Y.4    Pangault, C.5    Guilloux, V.6    Beauplet, A.7    Fauchet, R.8    Amiot, L.9
  • 163
    • 84906258559 scopus 로고    scopus 로고
    • In vivo evidence that secretion of HLA-G by immunogenic tumor cells allows their evasion from immunosurveillance
    • Loumagne, L., Baudhuin, J., Favier, B., Montespan, F., Carosella, E.D., Rouas-Freiss, N., In vivo evidence that secretion of HLA-G by immunogenic tumor cells allows their evasion from immunosurveillance. Int J Cancer 135:9 (2014), 2107–2117.
    • (2014) Int J Cancer , vol.135 , Issue.9 , pp. 2107-2117
    • Loumagne, L.1    Baudhuin, J.2    Favier, B.3    Montespan, F.4    Carosella, E.D.5    Rouas-Freiss, N.6
  • 164
  • 165
    • 84896779371 scopus 로고    scopus 로고
    • The roles of mesenchymal stem cells in tumor inflammatory microenvironment
    • Sun, Z., Wang, S., Zhao, R.C., The roles of mesenchymal stem cells in tumor inflammatory microenvironment. J Hematol Oncol, 7, 2014, 14.
    • (2014) J Hematol Oncol , vol.7 , pp. 14
    • Sun, Z.1    Wang, S.2    Zhao, R.C.3
  • 168
    • 31544446571 scopus 로고    scopus 로고
    • Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
    • Huang, B., Pan, P.Y., Li, Q., Sato, A.I., Levy, D.E., Bromberg, J., Divino, C.M., Chen, S.H., Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res 66:2 (2006), 1123–1131.
    • (2006) Cancer Res , vol.66 , Issue.2 , pp. 1123-1131
    • Huang, B.1    Pan, P.Y.2    Li, Q.3    Sato, A.I.4    Levy, D.E.5    Bromberg, J.6    Divino, C.M.7    Chen, S.H.8


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