메뉴 건너뛰기




Volumn 129, Issue 1, 2017, Pages 13-21

Chronic graft-versus-host disease: Biological insights from preclinical and clinical studies

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIBODY; COLONY STIMULATING FACTOR 1; TRANSFORMING GROWTH FACTOR BETA;

EID: 85014917342     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2016-06-686618     Document Type: Review
Times cited : (208)

References (161)
  • 1
    • 84921666562 scopus 로고    scopus 로고
    • How we treat chronic graft-versus-host disease
    • Flowers ME, Martin PJ. How we treat chronic graft-versus-host disease. Blood. 2015;125(4): 606-615.
    • (2015) Blood , vol.125 , Issue.4 , pp. 606-615
    • Flowers, M.E.1    Martin, P.J.2
  • 2
    • 77949877713 scopus 로고    scopus 로고
    • Life expectancy in patients surviving more than 5 years after hematopoietic cell transplantation
    • Martin PJ, Counts GW Jr, Appelbaum FR, et al. Life expectancy in patients surviving more than 5 years after hematopoietic cell transplantation. J Clin Oncol. 2010;28(6):1011-1016.
    • (2010) J Clin Oncol. , vol.28 , Issue.6 , pp. 1011-1016
    • Martin, P.J.1    Counts, G.W.2    Appelbaum, F.R.3
  • 3
    • 79957958325 scopus 로고    scopus 로고
    • Long-term survival and late deaths after allogeneic hematopoietic cell transplantation
    • Wingard JR, Majhail NS, Brazauskas R, et al. Long-term survival and late deaths after allogeneic hematopoietic cell transplantation. J Clin Oncol. 2011;29(16):2230-2239.
    • (2011) J Clin Oncol. , vol.29 , Issue.16 , pp. 2230-2239
    • Wingard, J.R.1    Majhail, N.S.2    Brazauskas, R.3
  • 4
    • 80054090049 scopus 로고    scopus 로고
    • Global and organ-specific chronic graft-versus-host disease severity according to the 2005 NIH consensus criteria
    • Arai S, Jagasia M, Storer B, et al. Global and organ-specific chronic graft-versus-host disease severity according to the 2005 NIH consensus criteria. Blood. 2011;118(15):4242-4249.
    • (2011) Blood , vol.118 , Issue.15 , pp. 4242-4249
    • Arai, S.1    Jagasia, M.2    Storer, B.3
  • 5
    • 84866177173 scopus 로고    scopus 로고
    • Correlation between NIH composite skin score, patient-reported skin score, and outcome: Results from the chronic GVHD consortium
    • Jacobsohn DA, Kurland BF, Pidala J, et al. Correlation between NIH composite skin score, patient-reported skin score, and outcome: results from the Chronic GVHD Consortium. Blood. 2012;120(13):2545-2552.
    • (2012) Blood , vol.120 , Issue.13 , pp. 2545-2552
    • Jacobsohn, D.A.1    Kurland, B.F.2    Pidala, J.3
  • 6
    • 84924234213 scopus 로고    scopus 로고
    • NIH consensus development project on criteria for clinical trials in chronic graft-versus-host disease: II
    • The 2014 Pathology Working Group Report
    • Shulman HM, Cardona DM, Greenson JK, et al. NIH Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: II. The 2014 Pathology Working Group Report. Biol Blood Marrow Transplant. 2015; 21(4):589-603.
    • (2015) Biol Blood Marrow Transplant. , vol.21 , Issue.4 , pp. 589-603
    • Shulman, H.M.1    Cardona, D.M.2    Greenson, J.K.3
  • 7
    • 84937709873 scopus 로고    scopus 로고
    • National institutes of health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: VI. The 2014 clinical trial design working group report
    • Martin PJ, Lee SJ, Przepiorka D, et al. National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: VI. The 2014 Clinical Trial Design Working Group Report. Biol Blood Marrow Transplant. 2015;21(8):1343-1359.
    • (2015) Biol Blood Marrow Transplant. , vol.21 , Issue.8 , pp. 1343-1359
    • Martin, P.J.1    Lee, S.J.2    Przepiorka, D.3
  • 8
    • 84861576998 scopus 로고    scopus 로고
    • Advances in graft-versus-host disease biology and therapy
    • Blazar BR, Murphy WJ, Abedi M. Advances in graft-versus-host disease biology and therapy. Nat Rev Immunol. 2012;12(6):443-458.
    • (2012) Nat Rev Immunol. , vol.12 , Issue.6 , pp. 443-458
    • Blazar, B.R.1    Murphy, W.J.2    Abedi, M.3
  • 9
    • 40649125501 scopus 로고    scopus 로고
    • Murine models of chronic graft-versus-host disease: Insights and unresolved issues
    • Chu YW, Gress RE. Murine models of chronic graft-versus-host disease: insights and unresolved issues. Biol Blood Marrow Transplant. 2008;14(4):365-378.
    • (2008) Biol Blood Marrow Transplant. , vol.14 , Issue.4 , pp. 365-378
    • Chu, Y.W.1    Gress, R.E.2
  • 10
    • 84925665321 scopus 로고    scopus 로고
    • Advances and challenges in immunotherapy for solid organ and hematopoietic stem cell transplantation
    • McDonald-Hyman C, Turka LA, Blazar BR. Advances and challenges in immunotherapy for solid organ and hematopoietic stem cell transplantation. Sci Transl Med. 2015;7(280): 280rv2.
    • (2015) Sci Transl Med. , vol.7 , Issue.280 , pp. 280rv2
    • McDonald-Hyman, C.1    Turka, L.A.2    Blazar, B.R.3
  • 11
    • 79956121863 scopus 로고    scopus 로고
    • Mouse models of graft-versus-host disease: Advances and limitations
    • Schroeder MA, DiPersio JF. Mouse models of graft-versus-host disease: advances and limitations. Dis Model Mech. 2011;4(3):318-333.
    • (2011) Dis Model Mech. , vol.4 , Issue.3 , pp. 318-333
    • Schroeder, M.A.1    DiPersio, J.F.2
  • 12
    • 33846000279 scopus 로고    scopus 로고
    • Transplantation's greatest challenges: Advances in chronic graft-versus-host disease
    • Shlomchik WD, Lee SJ, Couriel D, Pavletic SZ. Transplantation's greatest challenges: advances in chronic graft-versus-host disease. Biol Blood Marrow Transplant. 2007;13(1 suppl 1):2-10.
    • (2007) Biol Blood Marrow Transplant. , vol.13 , Issue.1 , pp. 2-10
    • Shlomchik, W.D.1    Lee, S.J.2    Couriel, D.3    Pavletic, S.Z.4
  • 13
    • 84904470709 scopus 로고    scopus 로고
    • Current issues in chronic graft-versus-host disease
    • Socié G, Ritz J. Current issues in chronic graft-versus-host disease. Blood. 2014;124(3): 374-384.
    • (2014) Blood , vol.124 , Issue.3 , pp. 374-384
    • Socié, G.1    Ritz, J.2
  • 14
    • 84922766049 scopus 로고    scopus 로고
    • National institutes of health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. The 2014 diagnosis and staging working group report
    • Jagasia MH, Greinix HT, Arora M, et al. National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: I. The 2014 Diagnosis and Staging Working Group report. Biol Blood Marrow Transplant. 2015;21(3): 389-401.
    • (2015) Biol Blood Marrow Transplant. , vol.21 , Issue.3 , pp. 389-401
    • Jagasia, M.H.1    Greinix, H.T.2    Arora, M.3
  • 15
    • 0034655607 scopus 로고    scopus 로고
    • Granulocyte-colony stimulating factor mobilizes T helper 2-inducing dendritic cells
    • Arpinati M, Green CL, Heimfeld S, Heuser JE, Anasetti C. Granulocyte-colony stimulating factor mobilizes T helper 2-inducing dendritic cells. Blood. 2000;95(8):2484-2490.
    • (2000) Blood , vol.95 , Issue.8 , pp. 2484-2490
    • Arpinati, M.1    Green, C.L.2    Heimfeld, S.3    Heuser, J.E.4    Anasetti, C.5
  • 16
    • 1942425058 scopus 로고    scopus 로고
    • Donor treatment with pegylated G-CSF augments the generation of IL-10-producing regulatory T cells and promotes transplantation tolerance
    • Morris ES, MacDonald KP, Rowe V, et al. Donor treatment with pegylated G-CSF augments the generation of IL-10-producing regulatory T cells and promotes transplantation tolerance. Blood. 2004;103(9):3573-3581.
    • (2004) Blood , vol.103 , Issue.9 , pp. 3573-3581
    • Morris, E.S.1    MacDonald, K.P.2    Rowe, V.3
  • 17
    • 0028843985 scopus 로고
    • Pretreatment of donor mice with granulocyte colony-stimulating factor polarizes donor T lymphocytes toward type-2 cytokine production and reduces severity of experimental graft-versus-host disease
    • Pan L, Delmonte J Jr, Jalonen CK, Ferrara JL. Pretreatment of donor mice with granulocyte colony-stimulating factor polarizes donor T lymphocytes toward type-2 cytokine production and reduces severity of experimental graft-versus-host disease. Blood. 1995;86(12): 4422-4429.
    • (1995) Blood , vol.86 , Issue.12 , pp. 4422-4429
    • Pan, L.1    Delmonte, J.2    Jalonen, C.K.3    Ferrara, J.L.4
  • 18
    • 84867592111 scopus 로고    scopus 로고
    • Peripheral-blood stem cells versus bone marrow from unrelated donors
    • Anasetti C, Logan BR, Lee SJ, et al; Blood and Marrow Transplant Clinical Trials Network. Peripheral-blood stem cells versus bone marrow from unrelated donors. N Engl J Med. 2012; 367(16):1487-1496.
    • (2012) N Engl J Med. , vol.367 , Issue.16 , pp. 1487-1496
    • Anasetti, C.1    Logan, B.R.2    Lee, S.J.3
  • 19
    • 24644503670 scopus 로고    scopus 로고
    • Allogeneic peripheral blood stem-cell compared with bone marrow transplantation in the management of hematologic malignancies: An individual patient data meta-analysis of nine randomized trials
    • Stem Cell Trialists' Collaborative Group. Allogeneic peripheral blood stem-cell compared with bone marrow transplantation in the management of hematologic malignancies: an individual patient data meta-analysis of nine randomized trials. J Clin Oncol. 2005;23(22): 5074-5087.
    • (2005) J Clin Oncol. , vol.23 , Issue.22 , pp. 5074-5087
  • 20
    • 79953109315 scopus 로고    scopus 로고
    • Comparative analysis of risk factors for acute graft-versus-host disease and for chronic graft-versus-host disease according to national institutes of health consensus criteria
    • Flowers ME, Inamoto Y, Carpenter PA, et al. Comparative analysis of risk factors for acute graft-versus-host disease and for chronic graft-versus-host disease according to National Institutes of Health consensus criteria. Blood. 2011;117(11):3214-3219.
    • (2011) Blood , vol.117 , Issue.11 , pp. 3214-3219
    • Flowers, M.E.1    Inamoto, Y.2    Carpenter, P.A.3
  • 21
    • 36348980530 scopus 로고    scopus 로고
    • Absence of regulatory T-cell control of TH1 and TH17 cells is responsible for the autoimmune-mediated pathology in chronic graft-versus-host disease
    • Chen X, Vodanovic-Jankovic S, Johnson B, Keller M, Komorowski R, Drobyski WR. Absence of regulatory T-cell control of TH1 and TH17 cells is responsible for the autoimmune-mediated pathology in chronic graft-versus-host disease. Blood. 2007;110(10):3804-3813.
    • (2007) Blood , vol.110 , Issue.10 , pp. 3804-3813
    • Chen, X.1    Vodanovic-Jankovic, S.2    Johnson, B.3    Keller, M.4    Komorowski, R.5    Drobyski, W.R.6
  • 22
    • 4444354779 scopus 로고    scopus 로고
    • Recipient CD4+ T cells that survive irradiation regulate chronic graft-versus-host disease
    • Anderson BE, McNiff JM, Matte C, Athanasiadis I, Shlomchik WD, Shlomchik MJ. Recipient CD4+ T cells that survive irradiation regulate chronic graft-versus-host disease. Blood. 2004; 104(5):1565-1573.
    • (2004) Blood , vol.104 , Issue.5 , pp. 1565-1573
    • Anderson, B.E.1    McNiff, J.M.2    Matte, C.3    Athanasiadis, I.4    Shlomchik, W.D.5    Shlomchik, M.J.6
  • 23
    • 20444362731 scopus 로고    scopus 로고
    • Emergent autoimmunity in graft-versus-host disease
    • Tivol E, Komorowski R, Drobyski WR. Emergent autoimmunity in graft-versus-host disease. Blood. 2005;105(12):4885-4891.
    • (2005) Blood , vol.105 , Issue.12 , pp. 4885-4891
    • Tivol, E.1    Komorowski, R.2    Drobyski, W.R.3
  • 24
    • 37449004090 scopus 로고    scopus 로고
    • CD4+ T cells generated de novo from donor hemopoietic stem cells mediate the evolution from acute to chronic graft-versus-host disease
    • Zhang Y, Hexner E, Frank D, Emerson SG. CD4+ T cells generated de novo from donor hemopoietic stem cells mediate the evolution from acute to chronic graft-versus-host disease. J Immunol. 2007;179(5):3305-3314.
    • (2007) J Immunol. , vol.179 , Issue.5 , pp. 3305-3314
    • Zhang, Y.1    Hexner, E.2    Frank, D.3    Emerson, S.G.4
  • 26
    • 84856908923 scopus 로고    scopus 로고
    • Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans
    • Srinivasan M, Flynn R, Price A, et al. Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans. Blood. 2012;119(6):1570-1580.
    • (2012) Blood , vol.119 , Issue.6 , pp. 1570-1580
    • Srinivasan, M.1    Flynn, R.2    Price, A.3
  • 27
    • 84879621050 scopus 로고    scopus 로고
    • Thymic damage, impaired negative selection, and development of chronic graft-versus-host disease caused by donor CD4+ and CD8+ T cells
    • Wu T, Young JS, Johnston H, et al. Thymic damage, impaired negative selection, and development of chronic graft-versus-host disease caused by donor CD4+ and CD8+ T cells. J Immunol. 2013;191(1):488-499.
    • (2013) J Immunol. , vol.191 , Issue.1 , pp. 488-499
    • Wu, T.1    Young, J.S.2    Johnston, H.3
  • 28
    • 77955873442 scopus 로고    scopus 로고
    • Stem cell mobilization with G-CSF induces type 17 differentiation and promotes scleroderma
    • Hill GR, Olver SD, Kuns RD, et al. Stem cell mobilization with G-CSF induces type 17 differentiation and promotes scleroderma. Blood. 2010;116(5):819-828.
    • (2010) Blood , vol.116 , Issue.5 , pp. 819-828
    • Hill, G.R.1    Olver, S.D.2    Kuns, R.D.3
  • 29
    • 84902668500 scopus 로고    scopus 로고
    • Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans
    • Flynn R, Du J, Veenstra RG, et al. Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans. Blood. 2014;123(25):3988-3998.
    • (2014) Blood , vol.123 , Issue.25 , pp. 3988-3998
    • Flynn, R.1    Du, J.2    Veenstra, R.G.3
  • 31
    • 0031020849 scopus 로고    scopus 로고
    • Graft-versus-host-disease-associated lymphoid hypoplasia and B cell dysfunction is dependent upon donor T cell-mediated fas-ligand function, but not perforin function
    • Baker MB, Riley RL, Podack ER, Levy RB. Graft-versus-host-disease-associated lymphoid hypoplasia and B cell dysfunction is dependent upon donor T cell-mediated Fas-ligand function, but not perforin function. Proc Natl Acad Sci USA. 1997;94(4):1366-1371.
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.4 , pp. 1366-1371
    • Baker, M.B.1    Riley, R.L.2    Podack, E.R.3    Levy, R.B.4
  • 32
    • 0027425469 scopus 로고
    • Suppression of B-cell development as a result of selective expansion of donor T cells during the minor H antigen graft-versus-host reaction
    • Garvy BA, Elia JM, Hamilton BL, Riley RL. Suppression of B-cell development as a result of selective expansion of donor T cells during the minor H antigen graft-versus-host reaction. Blood. 1993;82(9):2758-2766.
    • (1993) Blood , vol.82 , Issue.9 , pp. 2758-2766
    • Garvy, B.A.1    Elia, J.M.2    Hamilton, B.L.3    Riley, R.L.4
  • 33
    • 0035880251 scopus 로고    scopus 로고
    • Factors influencing B lymphopoiesis after allogeneic hematopoietic cell transplantation
    • Storek J, Wells D, Dawson MA, Storer B, Maloney DG. Factors influencing B lymphopoiesis after allogeneic hematopoietic cell transplantation. Blood. 2001;98(2):489-491.
    • (2001) Blood , vol.98 , Issue.2 , pp. 489-491
    • Storek, J.1    Wells, D.2    Dawson, M.A.3    Storer, B.4    Maloney, D.G.5
  • 34
    • 57249095766 scopus 로고    scopus 로고
    • The immunopathology of thymic GVHD
    • Krenger W, Holländer GA. The immunopathology of thymic GVHD. Semin Immunopathol. 2008;30(4):439-456.
    • (2008) Semin Immunopathol. , vol.30 , Issue.4 , pp. 439-456
    • Krenger, W.1    Holländer, G.A.2
  • 35
    • 0033998917 scopus 로고    scopus 로고
    • Graft-versus-host-disease-associated thymic damage results in the appearance of T cell clones with anti-host reactivity
    • van den Brink MR, Moore E, Ferrara JL, Burakoff SJ. Graft-versus-host-disease-associated thymic damage results in the appearance of T cell clones with anti-host reactivity. Transplantation. 2000;69(3):446-449.
    • (2000) Transplantation , vol.69 , Issue.3 , pp. 446-449
    • Van Den Brink, M.R.1    Moore, E.2    Ferrara, J.L.3    Burakoff, S.J.4
  • 36
    • 84928492197 scopus 로고    scopus 로고
    • Impaired thymic expression of tissue-restricted antigens licenses the de novo generation of autoreactive CD4+ T cells in acute GVHD
    • Dertschnig S, Hauri-Hohl MM, Vollmer M, Holländer GA, Krenger W. Impaired thymic expression of tissue-restricted antigens licenses the de novo generation of autoreactive CD4+ T cells in acute GVHD. Blood. 2015;125(17): 2720-2723.
    • (2015) Blood , vol.125 , Issue.17 , pp. 2720-2723
    • Dertschnig, S.1    Hauri-Hohl, M.M.2    Vollmer, M.3    Holländer, G.A.4    Krenger, W.5
  • 37
    • 0028294132 scopus 로고
    • Loss of normal thymic repertoire selection and persistence of autoreactive T cells in graft vs host disease
    • Holländer GA, Widmer B, Burakoff SJ. Loss of normal thymic repertoire selection and persistence of autoreactive T cells in graft vs host disease. J Immunol. 1994;152(4): 1609-1617.
    • (1994) J Immunol. , vol.152 , Issue.4 , pp. 1609-1617
    • Holländer, G.A.1    Widmer, B.2    Burakoff, S.J.3
  • 38
    • 33846910425 scopus 로고    scopus 로고
    • Donor-derived thymic-dependent T cells cause chronic graft-versus-host disease
    • Sakoda Y, Hashimoto D, Asakura S, et al. Donor-derived thymic-dependent T cells cause chronic graft-versus-host disease. Blood. 2007; 109(4):1756-1764.
    • (2007) Blood , vol.109 , Issue.4 , pp. 1756-1764
    • Sakoda, Y.1    Hashimoto, D.2    Asakura, S.3
  • 39
    • 70350343544 scopus 로고    scopus 로고
    • Induction of intestinal th17 cells by segmented filamentous bacteria
    • Ivanov II, Atarashi K, Manel N, et al. Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell. 2009;139(3):485-498.
    • (2009) Cell. , vol.139 , Issue.3 , pp. 485-498
    • Ivanov, I.I.1    Atarashi, K.2    Manel, N.3
  • 40
    • 7144257175 scopus 로고    scopus 로고
    • Cytokine and cytotoxic pathways of NK cell rejection of class I-deficient bone marrow grafts: Influence of mouse colony environment
    • Bennett M, Taylor PA, Austin M, et al. Cytokine and cytotoxic pathways of NK cell rejection of class I-deficient bone marrow grafts: influence of mouse colony environment. Int Immunol. 1998; 10(6):785-790.
    • (1998) Int Immunol. , vol.10 , Issue.6 , pp. 785-790
    • Bennett, M.1    Taylor, P.A.2    Austin, M.3
  • 41
    • 84964918435 scopus 로고    scopus 로고
    • Normalizing the environment recapitulates adult human immune traits in laboratory mice
    • Beura LK, Hamilton SE, Bi K, et al. Normalizing the environment recapitulates adult human immune traits in laboratory mice. Nature. 2016; 532(7600):512-516.
    • (2016) Nature , vol.532 , Issue.7600 , pp. 512-516
    • Beura, L.K.1    Hamilton, S.E.2    Bi, K.3
  • 42
    • 84861539347 scopus 로고    scopus 로고
    • Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation
    • Jenq RR, Ubeda C, Taur Y, et al. Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation. J Exp Med. 2012;209(5):903-911.
    • (2012) J Exp Med. , vol.209 , Issue.5 , pp. 903-911
    • Jenq, R.R.1    Ubeda, C.2    Taur, Y.3
  • 43
    • 84961392222 scopus 로고    scopus 로고
    • Gut microbiome-derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease
    • Mathewson ND, Jenq R, Mathew AV, et al. Gut microbiome-derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease. Nat Immunol. 2016; 17(5):505-513.
    • (2016) Nat Immunol. , vol.17 , Issue.5 , pp. 505-513
    • Mathewson, N.D.1    Jenq, R.2    Mathew, A.V.3
  • 44
    • 84969591057 scopus 로고    scopus 로고
    • Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice
    • Shono Y, Docampo MD, Peled JU, et al. Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice. Sci Transl Med. 2016;8(339): 339ra71.
    • (2016) Sci Transl Med. , vol.8 , Issue.339 , pp. 339ra71
    • Shono, Y.1    Docampo, M.D.2    Peled, J.U.3
  • 45
    • 0036246614 scopus 로고    scopus 로고
    • Enhanced allostimulatory activity of host antigen-presenting cells in old mice intensifies acute graft-versus-host disease
    • Ordemann R, Hutchinson R, Friedman J, et al. Enhanced allostimulatory activity of host antigen-presenting cells in old mice intensifies acute graft-versus-host disease. J Clin Invest. 2002; 109(9):1249-1256.
    • (2002) J Clin Invest. , vol.109 , Issue.9 , pp. 1249-1256
    • Ordemann, R.1    Hutchinson, R.2    Friedman, J.3
  • 46
    • 84860319360 scopus 로고    scopus 로고
    • Induction of acute GVHD by sex-mismatched H-Y antigens in the absence of functional radiosensitive host hematopoietic-derived antigen-presenting cells
    • Toubai T, Tawara I, Sun Y, et al. Induction of acute GVHD by sex-mismatched H-Y antigens in the absence of functional radiosensitive host hematopoietic-derived antigen-presenting cells. Blood. 2012;119(16):3844-3853.
    • (2012) Blood , vol.119 , Issue.16 , pp. 3844-3853
    • Toubai, T.1    Tawara, I.2    Sun, Y.3
  • 47
    • 20144386800 scopus 로고    scopus 로고
    • Antibody responses to H-Y minor histocompatibility antigens correlate with chronic graft-versus-host disease and disease remission
    • Miklos DB, Kim HT, Miller KH, et al. Antibody responses to H-Y minor histocompatibility antigens correlate with chronic graft-versus-host disease and disease remission. Blood. 2005; 105(7):2973-2978.
    • (2005) Blood , vol.105 , Issue.7 , pp. 2973-2978
    • Miklos, D.B.1    Kim, H.T.2    Miller, K.H.3
  • 48
    • 2442534666 scopus 로고    scopus 로고
    • Minor histocompatibility antigen DBY elicits a coordinated B and T cell response after allogeneic stem cell transplantation
    • Zorn E, Miklos DB, Floyd BH, et al. Minor histocompatibility antigen DBY elicits a coordinated B and T cell response after allogeneic stem cell transplantation. J Exp Med. 2004;199(8):1133-1142.
    • (2004) J Exp Med. , vol.199 , Issue.8 , pp. 1133-1142
    • Zorn, E.1    Miklos, D.B.2    Floyd, B.H.3
  • 49
    • 0034193057 scopus 로고    scopus 로고
    • The primacy of the gastrointestinal tract as a target organ of acute graft-versus-host disease: Rationale for the use of cytokine shields in allogeneic bone marrow transplantation
    • Hill GR, Ferrara JL. The primacy of the gastrointestinal tract as a target organ of acute graft-versus-host disease: rationale for the use of cytokine shields in allogeneic bone marrow transplantation. Blood. 2000;95(9):2754-2759.
    • (2000) Blood , vol.95 , Issue.9 , pp. 2754-2759
    • Hill, G.R.1    Ferrara, J.L.2
  • 50
    • 84942275251 scopus 로고    scopus 로고
    • Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects
    • Gartlan KH, Markey KA, Varelias A, et al. Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects. Blood. 2015; 126(13):1609-1620.
    • (2015) Blood , vol.126 , Issue.13 , pp. 1609-1620
    • Gartlan, K.H.1    Markey, K.A.2    Varelias, A.3
  • 51
    • 59649098784 scopus 로고    scopus 로고
    • IL-17 contributes to CD4-mediated graft-versus-host disease
    • Kappel LW, Goldberg GL, King CG, et al. IL-17 contributes to CD4-mediated graft-versus-host disease. Blood. 2009;113(4):945-952.
    • (2009) Blood , vol.113 , Issue.4 , pp. 945-952
    • Kappel, L.W.1    Goldberg, G.L.2    King, C.G.3
  • 52
    • 70449494642 scopus 로고    scopus 로고
    • Reciprocal differentiation and tissue-specific pathogenesis of th1, th2, and th17 cells in graft-versus-host disease
    • Yi T, Chen Y, Wang L, et al. Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease. Blood. 2009;114(14):3101-3112.
    • (2009) Blood , vol.114 , Issue.14 , pp. 3101-3112
    • Yi, T.1    Chen, Y.2    Wang, L.3
  • 53
    • 60849118676 scopus 로고    scopus 로고
    • In vitro-differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations
    • Carlson MJ, West ML, Coghill JM, Panoskaltsis-Mortari A, Blazar BR, Serody JS. In vitro-differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations. Blood. 2009;113(6):1365-1374.
    • (2009) Blood , vol.113 , Issue.6 , pp. 1365-1374
    • Carlson, M.J.1    West, M.L.2    Coghill, J.M.3    Panoskaltsis-Mortari, A.4    Blazar, B.R.5    Serody, J.S.6
  • 54
    • 77955513410 scopus 로고    scopus 로고
    • Recipient B cells are not required for graft-versus-host disease induction
    • Matte-Martone C, Wang X, Anderson B, et al. Recipient B cells are not required for graft-versus-host disease induction. Biol Blood Marrow Transplant. 2010;16(9):1222-1230.
    • (2010) Biol Blood Marrow Transplant. , vol.16 , Issue.9 , pp. 1222-1230
    • Matte-Martone, C.1    Wang, X.2    Anderson, B.3
  • 55
    • 33749358615 scopus 로고    scopus 로고
    • Host B cells produce IL-10 following TBI and attenuate acute GVHD after allogeneic bone marrow transplantation
    • Rowe V, Banovic T, MacDonald KP, et al. Host B cells produce IL-10 following TBI and attenuate acute GVHD after allogeneic bone marrow transplantation. Blood. 2006;108(7): 2485-2492.
    • (2006) Blood , vol.108 , Issue.7 , pp. 2485-2492
    • Rowe, V.1    Banovic, T.2    MacDonald, K.P.3
  • 56
    • 84901838956 scopus 로고    scopus 로고
    • Donor and host B cell-derived IL-10 contributes to suppression of graft-versus-host disease
    • Weber M, Stein P, Prüfer S, et al. Donor and host B cell-derived IL-10 contributes to suppression of graft-versus-host disease. Eur J Immunol. 2014;44(6):1857-1865.
    • (2014) Eur J Immunol. , vol.44 , Issue.6 , pp. 1857-1865
    • Weber, M.1    Stein, P.2    Prüfer, S.3
  • 57
    • 85047691367 scopus 로고    scopus 로고
    • Memory CD4+ T cells do not induce graft-versus-host disease
    • Anderson BE, McNiff J, Yan J, et al. Memory CD4+ T cells do not induce graft-versus-host disease. J Clin Invest. 2003;112(1):101-108.
    • (2003) J Clin Invest. , vol.112 , Issue.1 , pp. 101-108
    • Anderson, B.E.1    McNiff, J.2    Yan, J.3
  • 58
    • 84936806071 scopus 로고    scopus 로고
    • Outcomes of acute leukemia patients transplanted with naive T cell-depleted stem cell grafts
    • Bleakley M, Heimfeld S, Loeb KR, et al. Outcomes of acute leukemia patients transplanted with naive T cell-depleted stem cell grafts. J Clin Invest. 2015;125(7):2677-2689.
    • (2015) J Clin Invest. , vol.125 , Issue.7 , pp. 2677-2689
    • Bleakley, M.1    Heimfeld, S.2    Loeb, K.R.3
  • 59
    • 0035282934 scopus 로고    scopus 로고
    • Factors affecting thymic function after allogeneic hematopoietic stem cell transplantation
    • Weinberg K, Blazar BR, Wagner JE, et al. Factors affecting thymic function after allogeneic hematopoietic stem cell transplantation. Blood. 2001;97(5):1458-1466.
    • (2001) Blood , vol.97 , Issue.5 , pp. 1458-1466
    • Weinberg, K.1    Blazar, B.R.2    Wagner, J.E.3
  • 60
    • 84862506107 scopus 로고    scopus 로고
    • Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets
    • Markey KA, Koyama M, Kuns RD, et al. Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets. Blood. 2012;119(24):5918-5930.
    • (2012) Blood , vol.119 , Issue.24 , pp. 5918-5930
    • Markey, K.A.1    Koyama, M.2    Kuns, R.D.3
  • 61
    • 79953123445 scopus 로고    scopus 로고
    • Effector CD4+ T cells, the cytokines they generate, and GVHD: Something old and something new
    • Coghill JM, Sarantopoulos S, Moran TP, Murphy WJ, Blazar BR, Serody JS. Effector CD4+ T cells, the cytokines they generate, and GVHD: something old and something new. Blood. 2011; 117(12):3268-3276.
    • (2011) Blood , vol.117 , Issue.12 , pp. 3268-3276
    • Coghill, J.M.1    Sarantopoulos, S.2    Moran, T.P.3    Murphy, W.J.4    Blazar, B.R.5    Serody, J.S.6
  • 62
    • 0027452843 scopus 로고
    • Differential cytokine expression in acute and chronic murine graft-versus-host-disease
    • Allen RD, Staley TA, Sidman CL. Differential cytokine expression in acute and chronic murine graft-versus-host-disease. Eur J Immunol. 1993; 23(2):333-337.
    • (1993) Eur J Immunol. , vol.23 , Issue.2 , pp. 333-337
    • Allen, R.D.1    Staley, T.A.2    Sidman, C.L.3
  • 63
    • 0027971672 scopus 로고
    • IL-12 stimulates the development of acute graft-versus-host disease in mice that normally would develop chronic, autoimmune graft-versus-host disease
    • Via CS, Rus V, Gately MK, Finkelman FD. IL-12 stimulates the development of acute graft-versus-host disease in mice that normally would develop chronic, autoimmune graft-versus-host disease. J Immunol. 1994;153(9):4040-4047.
    • (1994) J Immunol. , vol.153 , Issue.9 , pp. 4040-4047
    • Via, C.S.1    Rus, V.2    Gately, M.K.3    Finkelman, F.D.4
  • 64
    • 0032211796 scopus 로고    scopus 로고
    • Differential effects of the absence of interferon-gamma and IL-4 in acute graft-versus-host disease after allogeneic bone marrow transplantation in mice
    • Murphy WJ, Welniak LA, Taub DD, et al. Differential effects of the absence of interferon-gamma and IL-4 in acute graft-versus-host disease after allogeneic bone marrow transplantation in mice. J Clin Invest. 1998; 102(9):1742-1748.
    • (1998) J Clin Invest. , vol.102 , Issue.9 , pp. 1742-1748
    • Murphy, W.J.1    Welniak, L.A.2    Taub, D.D.3
  • 66
    • 33846966636 scopus 로고    scopus 로고
    • A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage
    • Steinman L. A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage. Nat Med. 2007; 13(2):139-145.
    • (2007) Nat Med. , vol.13 , Issue.2 , pp. 139-145
    • Steinman, L.1
  • 67
    • 42649134787 scopus 로고    scopus 로고
    • Clinical association of serum interleukin-17 levels in systemic sclerosis: Is systemic sclerosis a th17 disease?
    • Murata M, Fujimoto M, Matsushita T, et al. Clinical association of serum interleukin-17 levels in systemic sclerosis: is systemic sclerosis a Th17 disease? J Dermatol Sci. 2008;50(3): 240-242.
    • (2008) J Dermatol Sci. , vol.50 , Issue.3 , pp. 240-242
    • Murata, M.1    Fujimoto, M.2    Matsushita, T.3
  • 68
    • 77956899738 scopus 로고    scopus 로고
    • Cell adhesion molecules regulate fibrotic process via th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model
    • Yoshizaki A, Yanaba K, Iwata Y, et al. Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model. J Immunol. 2010; 185(4):2502-2515.
    • (2010) J Immunol. , vol.185 , Issue.4 , pp. 2502-2515
    • Yoshizaki, A.1    Yanaba, K.2    Iwata, Y.3
  • 69
    • 85135870334 scopus 로고    scopus 로고
    • Proteomics analysis reveals a th17-prone cell population in presymptomatic graft-versus-host disease
    • Li W, Liu L, Gomez A, et al. Proteomics analysis reveals a Th17-prone cell population in presymptomatic graft-versus-host disease. JCI Insight. 2016;1(6).
    • (2016) JCI Insight. , vol.1 , Issue.6
    • Li, W.1    Liu, L.2    Gomez, A.3
  • 70
    • 73349105621 scopus 로고    scopus 로고
    • Interleukin-17-producing T-helper cells as new potential player mediating graft-versus-host disease in patients undergoing allogeneic stem-cell transplantation
    • Dander E, Balduzzi A, Zappa G, et al. Interleukin-17-producing T-helper cells as new potential player mediating graft-versus-host disease in patients undergoing allogeneic stem-cell transplantation. Transplantation. 2009; 88(11):1261-1272.
    • (2009) Transplantation , vol.88 , Issue.11 , pp. 1261-1272
    • Dander, E.1    Balduzzi, A.2    Zappa, G.3
  • 71
    • 84855406581 scopus 로고    scopus 로고
    • The IL-17 differentiation pathway and its role in transplant outcome
    • Serody JS, Hill GR. The IL-17 differentiation pathway and its role in transplant outcome. Biol Blood Marrow Transplant. 2012;18(1 suppl): S56-S61.
    • (2012) Biol Blood Marrow Transplant. , vol.18 , Issue.1 , pp. S56-S61
    • Serody, J.S.1    Hill, G.R.2
  • 72
    • 84897018784 scopus 로고    scopus 로고
    • Diverse T-cell responses characterize the different manifestations of cutaneous graft-versus-host disease
    • Brüggen MC, Klein I, Greinix H, et al. Diverse T-cell responses characterize the different manifestations of cutaneous graft-versus-host disease. Blood. 2014;123(2):290-299.
    • (2014) Blood , vol.123 , Issue.2 , pp. 290-299
    • Brüggen, M.C.1    Klein, I.2    Greinix, H.3
  • 73
    • 84974582736 scopus 로고    scopus 로고
    • Targeted rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a stat3-dependent mechanism
    • Flynn R, Paz K, Du J, et al. Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism. Blood. 2016; 127(17):2144-2154.
    • (2016) Blood , vol.127 , Issue.17 , pp. 2144-2154
    • Flynn, R.1    Paz, K.2    Du, J.3
  • 74
    • 84906308941 scopus 로고    scopus 로고
    • Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions
    • Lu L, Lan Q, Li Z, et al. Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions. Proc Natl Acad Sci USA. 2014;111(33): E3432-E3440.
    • (2014) Proc Natl Acad Sci USA , vol.111 , Issue.33 , pp. E3432-E3440
    • Lu, L.1    Lan, Q.2    Li, Z.3
  • 75
    • 84927511163 scopus 로고    scopus 로고
    • Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation
    • Varelias A, Gartlan KH, Kreijveld E, et al. Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation. Blood. 2015;125(15): 2435-2444.
    • (2015) Blood , vol.125 , Issue.15 , pp. 2435-2444
    • Varelias, A.1    Gartlan, K.H.2    Kreijveld, E.3
  • 76
    • 84925228691 scopus 로고    scopus 로고
    • Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: A phase 1/2 trial
    • Kennedy GA, Varelias A, Vuckovic S, et al. Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial. Lancet Oncol. 2014;15(13):1451-1459.
    • (2014) Lancet Oncol. , vol.15 , Issue.13 , pp. 1451-1459
    • Kennedy, G.A.1    Varelias, A.2    Vuckovic, S.3
  • 77
    • 37749021324 scopus 로고    scopus 로고
    • Cutting edge: An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity
    • Harris TJ, Grosso JF, Yen HR, et al. Cutting edge: an in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity. J Immunol. 2007;179(7): 4313-4317.
    • (2007) J Immunol. , vol.179 , Issue.7 , pp. 4313-4317
    • Harris, T.J.1    Grosso, J.F.2    Yen, H.R.3
  • 78
    • 76249133491 scopus 로고    scopus 로고
    • STAT3 signaling in CD4+ T cells is critical for the pathogenesis of chronic sclerodermatous graft-versus-host disease in a murine model
    • Radojcic V, Pletneva MA, Yen HR, et al. STAT3 signaling in CD4+ T cells is critical for the pathogenesis of chronic sclerodermatous graft-versus-host disease in a murine model. J Immunol. 2010;184(2):764-774.
    • (2010) J Immunol. , vol.184 , Issue.2 , pp. 764-774
    • Radojcic, V.1    Pletneva, M.A.2    Yen, H.R.3
  • 79
    • 78650442609 scopus 로고    scopus 로고
    • Cutaneous GVHD is associated with the expansion of tissue-localized th1 and not th17 cells
    • Broady R, Yu J, Chow V, et al. Cutaneous GVHD is associated with the expansion of tissue-localized Th1 and not Th17 cells. Blood. 2010; 116(25):5748-5751.
    • (2010) Blood , vol.116 , Issue.25 , pp. 5748-5751
    • Broady, R.1    Yu, J.2    Chow, V.3
  • 80
    • 84946149406 scopus 로고    scopus 로고
    • CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing th17 cells
    • Kara EE, McKenzie DR, Bastow CR, et al. CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells. Nat Commun. 2015;6:8644.
    • (2015) Nat Commun. , vol.6 , pp. 8644
    • Kara, E.E.1    McKenzie, D.R.2    Bastow, C.R.3
  • 81
    • 84878392088 scopus 로고    scopus 로고
    • Essentials of th17 cell commitment and plasticity
    • Muranski P, Restifo NP. Essentials of Th17 cell commitment and plasticity. Blood. 2013;121(13): 2402-2414.
    • (2013) Blood , vol.121 , Issue.13 , pp. 2402-2414
    • Muranski, P.1    Restifo, N.P.2
  • 82
    • 77956944306 scopus 로고    scopus 로고
    • Tc17 cells are capable of mediating immunity to vaccinia virus by acquisition of a cytotoxic phenotype
    • Yeh N, Glosson NL, Wang N, et al. Tc17 cells are capable of mediating immunity to vaccinia virus by acquisition of a cytotoxic phenotype. J Immunol. 2010;185(4):2089-2098.
    • (2010) J Immunol. , vol.185 , Issue.4 , pp. 2089-2098
    • Yeh, N.1    Glosson, N.L.2    Wang, N.3
  • 83
    • 73349101421 scopus 로고    scopus 로고
    • Tc17 CD8 T cells: Functional plasticity and subset diversity
    • Yen HR, Harris TJ, Wada S, et al. Tc17 CD8 T cells: functional plasticity and subset diversity. J Immunol. 2009;183(11):7161-7168.
    • (2009) J Immunol. , vol.183 , Issue.11 , pp. 7161-7168
    • Yen, H.R.1    Harris, T.J.2    Wada, S.3
  • 84
    • 84869805918 scopus 로고    scopus 로고
    • Chemokine-mediated tissue recruitment of CXCR3+ CD4+ T cells plays a major role in the pathogenesis of chronic GVHD
    • Croudace JE, Inman CF, Abbotts BE, et al. Chemokine-mediated tissue recruitment of CXCR3+ CD4+ T cells plays a major role in the pathogenesis of chronic GVHD. Blood. 2012; 120(20):4246-4255.
    • (2012) Blood , vol.120 , Issue.20 , pp. 4246-4255
    • Croudace, J.E.1    Inman, C.F.2    Abbotts, B.E.3
  • 85
    • 84894035968 scopus 로고    scopus 로고
    • Plasma CXCL9 elevations correlate with chronic GVHD diagnosis
    • Kitko CL, Levine JE, Storer BE, et al. Plasma CXCL9 elevations correlate with chronic GVHD diagnosis. Blood. 2014;123(5):786-793.
    • (2014) Blood , vol.123 , Issue.5 , pp. 786-793
    • Kitko, C.L.1    Levine, J.E.2    Storer, B.E.3
  • 86
    • 84891607730 scopus 로고    scopus 로고
    • Effector T cells require fatty acid metabolism during murine graft-versus-host disease
    • Byersdorfer CA, Tkachev V, Opipari AW, et al. Effector T cells require fatty acid metabolism during murine graft-versus-host disease. Blood. 2013;122(18):3230-3237.
    • (2013) Blood , vol.122 , Issue.18 , pp. 3230-3237
    • Byersdorfer, C.A.1    Tkachev, V.2    Opipari, A.W.3
  • 87
    • 79251500689 scopus 로고    scopus 로고
    • Manipulating the bioenergetics of alloreactive T cells causes their selective apoptosis and arrests graft-versus-host disease
    • Gatza E, Wahl DR, Opipari AW, et al. Manipulating the bioenergetics of alloreactive T cells causes their selective apoptosis and arrests graft-versus-host disease. Sci Transl Med. 2011;3(67):67ra8.
    • (2011) Sci Transl Med. , vol.3 , Issue.67 , pp. 67ra8
    • Gatza, E.1    Wahl, D.R.2    Opipari, A.W.3
  • 88
    • 84908577173 scopus 로고    scopus 로고
    • α-1-Antitrypsin (AAT)-modified donor cells suppress GVHD but enhance the GVL effect: A role for mitochondrial bioenergetics
    • Marcondes AM, Karoopongse E, Lesnikova M, et al. α-1-Antitrypsin (AAT)-modified donor cells suppress GVHD but enhance the GVL effect: a role for mitochondrial bioenergetics. Blood. 2014;124(18):2881-2891.
    • (2014) Blood , vol.124 , Issue.18 , pp. 2881-2891
    • Marcondes, A.M.1    Karoopongse, E.2    Lesnikova, M.3
  • 89
    • 84964600705 scopus 로고    scopus 로고
    • Metabolic reprogramming of alloantigen-activated T cells after hematopoietic cell transplantation
    • Nguyen HD, Chatterjee S, Haarberg KM, et al. Metabolic reprogramming of alloantigen-activated T cells after hematopoietic cell transplantation. J Clin Invest. 2016;126(4): 1337-1352.
    • (2016) J Clin Invest. , vol.126 , Issue.4 , pp. 1337-1352
    • Nguyen, H.D.1    Chatterjee, S.2    Haarberg, K.M.3
  • 90
    • 84891708632 scopus 로고    scopus 로고
    • Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality
    • Saha A, Aoyama K, Taylor PA, et al. Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality. Blood. 2013;122(17):3062-3073.
    • (2013) Blood , vol.122 , Issue.17 , pp. 3062-3073
    • Saha, A.1    Aoyama, K.2    Taylor, P.A.3
  • 91
    • 38149118876 scopus 로고    scopus 로고
    • Elevated numbers of immature/transitional CD21-B lymphocytes and deficiency of memory CD27+ B cells identify patients with active chronic graft-versus-host disease
    • Greinix HT, Pohlreich D, Kouba M, et al. Elevated numbers of immature/transitional CD21-B lymphocytes and deficiency of memory CD27+ B cells identify patients with active chronic graft-versus-host disease. Biol Blood Marrow Transplant. 2008;14(2):208-219.
    • (2008) Biol Blood Marrow Transplant. , vol.14 , Issue.2 , pp. 208-219
    • Greinix, H.T.1    Pohlreich, D.2    Kouba, M.3
  • 92
    • 77953203246 scopus 로고    scopus 로고
    • Longterm immune deficiency after allogeneic stem cell transplantation: B-cell deficiency is associated with late infections
    • Corre E, Carmagnat M, Busson M, et al. Longterm immune deficiency after allogeneic stem cell transplantation: B-cell deficiency is associated with late infections. Haematologica. 2010;95(6):1025-1029.
    • (2010) Haematologica , vol.95 , Issue.6 , pp. 1025-1029
    • Corre, E.1    Carmagnat, M.2    Busson, M.3
  • 93
    • 84866603654 scopus 로고    scopus 로고
    • B cells from patients with chronic GVHD are activated and primed for survival via BAFF-mediated pathways
    • Allen JL, Fore MS, Wooten J, et al. B cells from patients with chronic GVHD are activated and primed for survival via BAFF-mediated pathways. Blood. 2012;120(12):2529-2536.
    • (2012) Blood , vol.120 , Issue.12 , pp. 2529-2536
    • Allen, J.L.1    Fore, M.S.2    Wooten, J.3
  • 94
    • 84922572310 scopus 로고    scopus 로고
    • B10 cells: A functionally defined regulatory B cell subset
    • Tedder TF. B10 cells: a functionally defined regulatory B cell subset. J Immunol. 2015; 194(4):1395-1401.
    • (2015) J Immunol. , vol.194 , Issue.4 , pp. 1395-1401
    • Tedder, T.F.1
  • 95
    • 84907272636 scopus 로고    scopus 로고
    • Regulatory B cells are enriched within the IgM memory and transitional subsets in healthy donors but are deficient in chronic GVHD
    • Khoder A, Sarvaria A, Alsuliman A, et al. Regulatory B cells are enriched within the IgM memory and transitional subsets in healthy donors but are deficient in chronic GVHD. Blood. 2014;124(13):2034-2045.
    • (2014) Blood , vol.124 , Issue.13 , pp. 2034-2045
    • Khoder, A.1    Sarvaria, A.2    Alsuliman, A.3
  • 96
    • 84879154724 scopus 로고    scopus 로고
    • Donor-derived regulatory B cells are important for suppression of murine sclerodermatous chronic graft-versus-host disease
    • Le Huu D, Matsushita T, Jin G, et al. Donor-derived regulatory B cells are important for suppression of murine sclerodermatous chronic graft-versus-host disease. Blood. 2013;121(16): 3274-3283.
    • (2013) Blood , vol.121 , Issue.16 , pp. 3274-3283
    • Le Huu, D.1    Matsushita, T.2    Jin, G.3
  • 97
    • 84928536031 scopus 로고    scopus 로고
    • + and plasmablast-like regulatory B cells in human chronic graft-versus-host disease
    • + and plasmablast-like regulatory B cells in human chronic graft-versus-host disease. Blood. 2015;125(11):1830-1839.
    • (2015) Blood , vol.125 , Issue.11 , pp. 1830-1839
    • De Masson, A.1    Bouaziz, J.D.2    Le Buanec, H.3
  • 98
    • 42449105346 scopus 로고    scopus 로고
    • Biomarkers in newly diagnosed pediatric-extensive chronic graft-versus-host disease: A report from the children's oncology group
    • Fujii H, Cuvelier G, She K, et al. Biomarkers in newly diagnosed pediatric-extensive chronic graft-versus-host disease: a report from the Children's Oncology Group. Blood. 2008;111(6): 3276-3285.
    • (2008) Blood , vol.111 , Issue.6 , pp. 3276-3285
    • Fujii, H.1    Cuvelier, G.2    She, K.3
  • 99
    • 35948938957 scopus 로고    scopus 로고
    • High levels of B-cell activating factor in patients with active chronic graft-versus-host disease
    • Sarantopoulos S, Stevenson KE, Kim HT, et al. High levels of B-cell activating factor in patients with active chronic graft-versus-host disease. Clin Cancer Res. 2007;13(20):6107-6114.
    • (2007) Clin Cancer Res. , vol.13 , Issue.20 , pp. 6107-6114
    • Sarantopoulos, S.1    Stevenson, K.E.2    Kim, H.T.3
  • 100
    • 33644926381 scopus 로고    scopus 로고
    • The development of autoantibodies after allogeneic stem cell transplantation is related with chronic graft-vs-host disease and immune recovery
    • Patriarca F, Skert C, Sperotto A, et al. The development of autoantibodies after allogeneic stem cell transplantation is related with chronic graft-vs-host disease and immune recovery. Exp Hematol. 2006;34(3):389-396.
    • (2006) Exp Hematol. , vol.34 , Issue.3 , pp. 389-396
    • Patriarca, F.1    Skert, C.2    Sperotto, A.3
  • 101
    • 84862888262 scopus 로고    scopus 로고
    • Donor B cells in transplants augment clonal expansion and survival of pathogenic CD4+ T cells that mediate autoimmune-like chronic graft-versus-host disease
    • Young JS, Wu T, Chen Y, et al. Donor B cells in transplants augment clonal expansion and survival of pathogenic CD4+ T cells that mediate autoimmune-like chronic graft-versus-host disease. J Immunol. 2012;189(1):222-233.
    • (2012) J Immunol. , vol.189 , Issue.1 , pp. 222-233
    • Young, J.S.1    Wu, T.2    Chen, Y.3
  • 102
    • 9144219634 scopus 로고    scopus 로고
    • Antibody response to DBY minor histocompatibility antigen is induced after allogeneic stem cell transplantation and in healthy female donors
    • Miklos DB, Kim HT, Zorn E, et al. Antibody response to DBY minor histocompatibility antigen is induced after allogeneic stem cell transplantation and in healthy female donors. Blood. 2004;103(1):353-359.
    • (2004) Blood , vol.103 , Issue.1 , pp. 353-359
    • Miklos, D.B.1    Kim, H.T.2    Zorn, E.3
  • 103
    • 84874243928 scopus 로고    scopus 로고
    • H-Y antigen-binding B cells develop in male recipients of female hematopoietic cells and associate with chronic graft vs. Host disease
    • Sahaf B, Yang Y, Arai S, Herzenberg LA, Herzenberg LA, Miklos DB. H-Y antigen-binding B cells develop in male recipients of female hematopoietic cells and associate with chronic graft vs. host disease. Proc Natl Acad Sci USA. 2013;110(8):3005-3010.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.8 , pp. 3005-3010
    • Sahaf, B.1    Yang, Y.2    Arai, S.3    Herzenberg, L.A.4    Herzenberg, L.A.5    Miklos, D.B.6
  • 104
    • 34347386226 scopus 로고    scopus 로고
    • Stimulatory autoantibodies to PDGF receptor in patients with extensive chronic graft-versus-host disease
    • Svegliati S, Olivieri A, Campelli N, et al. Stimulatory autoantibodies to PDGF receptor in patients with extensive chronic graft-versus-host disease. Blood. 2007;110(1):237-241.
    • (2007) Blood , vol.110 , Issue.1 , pp. 237-241
    • Svegliati, S.1    Olivieri, A.2    Campelli, N.3
  • 105
    • 84880917678 scopus 로고    scopus 로고
    • Lack of association of platelet-derived growth factor (PDGF) receptor autoantibodies and severity of chronic graft-versus-host disease (GvHD)
    • Spies-Weisshart B, Schilling K, Böhmer F, Hochhaus A, Sayer HG, Scholl S. Lack of association of platelet-derived growth factor (PDGF) receptor autoantibodies and severity of chronic graft-versus-host disease (GvHD). J Cancer Res Clin Oncol. 2013;139(8): 1397-1404.
    • (2013) J Cancer Res Clin Oncol. , vol.139 , Issue.8 , pp. 1397-1404
    • Spies-Weisshart, B.1    Schilling, K.2    Böhmer, F.3    Hochhaus, A.4    Sayer, H.G.5    Scholl, S.6
  • 106
    • 84969256370 scopus 로고    scopus 로고
    • Antibodies from donor B cells perpetuate cutaneous chronic graft-versus-host disease in mice
    • Jin H, Ni X, Deng R, et al. Antibodies from donor B cells perpetuate cutaneous chronic graft-versus-host disease in mice. Blood. 2016; 127(18):2249-2260.
    • (2016) Blood , vol.127 , Issue.18 , pp. 2249-2260
    • Jin, H.1    Ni, X.2    Deng, R.3
  • 107
    • 65549132114 scopus 로고    scopus 로고
    • Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host disease
    • Sarantopoulos S, Stevenson KE, Kim HT, et al. Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host disease. Blood. 2009;113(16):3865-3874.
    • (2009) Blood , vol.113 , Issue.16 , pp. 3865-3874
    • Sarantopoulos, S.1    Stevenson, K.E.2    Kim, H.T.3
  • 108
    • 85014897556 scopus 로고    scopus 로고
    • Circulating T follicular helper cells with increased function during chronic graft-versus-host disease
    • Forcade E, Kim HT, Cutler C, et al. Circulating T follicular helper cells with increased function during chronic graft-versus-host disease. Blood. 2016;127(20):2489-2497.
    • (2016) Blood , vol.127 , Issue.20 , pp. 2489-2497
    • Forcade, E.1    Kim, H.T.2    Cutler, C.3
  • 109
    • 84963690258 scopus 로고    scopus 로고
    • Loss of T follicular helper cells in the peripheral blood of patients with chronic graft-versus-host disease
    • Knorr DA, Wang H, Aurora M, et al. Loss of T follicular helper cells in the peripheral blood of patients with chronic graft-versus-host disease. Biol Blood Marrow Transplant. 2016;22(5): 825-833.
    • (2016) Biol Blood Marrow Transplant. , vol.22 , Issue.5 , pp. 825-833
    • Knorr, D.A.1    Wang, H.2    Aurora, M.3
  • 110
    • 13744255589 scopus 로고    scopus 로고
    • Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
    • Duffield JS, Forbes SJ, Constandinou CM, et al. Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair. J Clin Invest. 2005;115(1):56-65.
    • (2005) J Clin Invest. , vol.115 , Issue.1 , pp. 56-65
    • Duffield, J.S.1    Forbes, S.J.2    Constandinou, C.M.3
  • 111
    • 46949087137 scopus 로고    scopus 로고
    • Murine gammaherpesvirus-induced fibrosis is associated with the development of alternatively activated macrophages
    • Gangadharan B, Hoeve MA, Allen JE, et al. Murine gammaherpesvirus-induced fibrosis is associated with the development of alternatively activated macrophages. J Leukoc Biol. 2008; 84(1):50-58.
    • (2008) J Leukoc Biol. , vol.84 , Issue.1 , pp. 50-58
    • Gangadharan, B.1    Hoeve, M.A.2    Allen, J.E.3
  • 112
    • 84907495480 scopus 로고    scopus 로고
    • CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease
    • Alexander KA, Flynn R, Lineburg KE, et al. CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease. J Clin Invest. 2014;124(10):4266-4280.
    • (2014) J Clin Invest. , vol.124 , Issue.10 , pp. 4266-4280
    • Alexander, K.A.1    Flynn, R.2    Lineburg, K.E.3
  • 113
    • 84908120736 scopus 로고    scopus 로고
    • IL-17A influences essential functions of the monocyte/macrophage lineage and is involved in advanced murine and human atherosclerosis
    • Erbel C, Akhavanpoor M, Okuyucu D, et al. IL-17A influences essential functions of the monocyte/macrophage lineage and is involved in advanced murine and human atherosclerosis. J Immunol. 2014;193(9):4344-4355.
    • (2014) J Immunol. , vol.193 , Issue.9 , pp. 4344-4355
    • Erbel, C.1    Akhavanpoor, M.2    Okuyucu, D.3
  • 114
    • 0346786463 scopus 로고    scopus 로고
    • Clearance of apoptotic cells: TGF-beta in the balance between inflammation and fibrosis
    • Clancy RM, Buyon JP. Clearance of apoptotic cells: TGF-beta in the balance between inflammation and fibrosis. J Leukoc Biol. 2003; 74(6):959-960.
    • (2003) J Leukoc Biol. , vol.74 , Issue.6 , pp. 959-960
    • Clancy, R.M.1    Buyon, J.P.2
  • 115
    • 0017264348 scopus 로고
    • The effect of neonatal rat graft-vs-host disease (GVHD) on fc receptor lymphocytes
    • Clancy J Jr, Tonder O, Boettcher CE. The effect of neonatal rat graft-vs-host disease (GVHD) on Fc receptor lymphocytes. J Immunol. 1976; 116(1):210-217.
    • (1976) J Immunol. , vol.116 , Issue.1 , pp. 210-217
    • Clancy, J.1    Tonder, O.2    Boettcher, C.E.3
  • 116
    • 84921417538 scopus 로고    scopus 로고
    • Therapeutic activity of multiple common γ-chain cytokine inhibition in acute and chronic GVHD
    • Hechinger AK, Smith BA, Flynn R, et al. Therapeutic activity of multiple common γ-chain cytokine inhibition in acute and chronic GVHD. Blood. 2015;125(3):570-580.
    • (2015) Blood , vol.125 , Issue.3 , pp. 570-580
    • Hechinger, A.K.1    Smith, B.A.2    Flynn, R.3
  • 117
    • 84908656083 scopus 로고    scopus 로고
    • Ibrutinib treatment ameliorates murine chronic graft-versus-host disease
    • Dubovsky JA, Flynn R, Du J, et al. Ibrutinib treatment ameliorates murine chronic graft-versus-host disease. J Clin Invest. 2014; 124(11):4867-4876.
    • (2014) J Clin Invest. , vol.124 , Issue.11 , pp. 4867-4876
    • Dubovsky, J.A.1    Flynn, R.2    Du, J.3
  • 118
    • 84933559790 scopus 로고    scopus 로고
    • Targeting syk-activated B cells in murine and human chronic graft-versus-host disease
    • Flynn R, Allen JL, Luznik L, et al. Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease. Blood. 2015;125(26): 4085-4094.
    • (2015) Blood , vol.125 , Issue.26 , pp. 4085-4094
    • Flynn, R.1    Allen, J.L.2    Luznik, L.3
  • 119
    • 84903991044 scopus 로고    scopus 로고
    • Administration of anti-CD20 mAb is highly effective in preventing but ineffective in treating chronic graft-versus-host disease while preserving strong graft-versus-leukemia effects
    • Johnston HF, Xu Y, Racine JJ, et al. Administration of anti-CD20 mAb is highly effective in preventing but ineffective in treating chronic graft-versus-host disease while preserving strong graft-versus-leukemia effects. Biol Blood Marrow Transplant. 2014;20(8): 1089-1103.
    • (2014) Biol Blood Marrow Transplant. , vol.20 , Issue.8 , pp. 1089-1103
    • Johnston, H.F.1    Xu, Y.2    Racine, J.J.3
  • 120
    • 84875498856 scopus 로고    scopus 로고
    • Development and maintenance of regulatory T cells
    • Ohkura N, Kitagawa Y, Sakaguchi S. Development and maintenance of regulatory T cells. Immunity. 2013;38(3):414-423.
    • (2013) Immunity. , vol.38 , Issue.3 , pp. 414-423
    • Ohkura, N.1    Kitagawa, Y.2    Sakaguchi, S.3
  • 121
    • 84940380928 scopus 로고    scopus 로고
    • A distinct function of regulatory T cells in tissue protection
    • Arpaia N, Green JA, Moltedo B, et al. A distinct function of regulatory T cells in tissue protection. Cell. 2015;162(5):1078-1089.
    • (2015) Cell. , vol.162 , Issue.5 , pp. 1078-1089
    • Arpaia, N.1    Green, J.A.2    Moltedo, B.3
  • 122
    • 84963593799 scopus 로고    scopus 로고
    • T follicular regulatory cells
    • Sage PT, Sharpe AH. T follicular regulatory cells. Immunol Rev. 2016;271(1):246-259.
    • (2016) Immunol Rev. , vol.271 , Issue.1 , pp. 246-259
    • Sage, P.T.1    Sharpe, A.H.2
  • 123
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol. 1995;155(3): 1151-1164.
    • (1995) J Immunol. , vol.155 , Issue.3 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 124
    • 33746809277 scopus 로고    scopus 로고
    • High donor FOXP3-positive regulatory T-cell (Treg) content is associated with a low risk of GVHD following HLA-matched allogeneic SCT
    • Rezvani K, Mielke S, Ahmadzadeh M, et al. High donor FOXP3-positive regulatory T-cell (Treg) content is associated with a low risk of GVHD following HLA-matched allogeneic SCT. Blood. 2006;108(4):1291-1297.
    • (2006) Blood , vol.108 , Issue.4 , pp. 1291-1297
    • Rezvani, K.1    Mielke, S.2    Ahmadzadeh, M.3
  • 125
    • 84862489728 scopus 로고    scopus 로고
    • Identification and expansion of highly suppressive CD8(+)FoxP3(+) regulatory T cells after experimental allogeneic bone marrow transplantation
    • Robb RJ, Lineburg KE, Kuns RD, et al. Identification and expansion of highly suppressive CD8(+)FoxP3(+) regulatory T cells after experimental allogeneic bone marrow transplantation. Blood. 2012;119(24):5898-5908.
    • (2012) Blood , vol.119 , Issue.24 , pp. 5898-5908
    • Robb, R.J.1    Lineburg, K.E.2    Kuns, R.D.3
  • 126
    • 84887416283 scopus 로고    scopus 로고
    • Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo
    • Zhang P, Tey SK, Koyama M, et al. Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo. J Immunol. 2013;191(10):5291-5303.
    • (2013) J Immunol. , vol.191 , Issue.10 , pp. 5291-5303
    • Zhang, P.1    Tey, S.K.2    Koyama, M.3
  • 127
    • 0141461418 scopus 로고    scopus 로고
    • CD4+ CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation
    • Edinger M, Hoffmann P, Ermann J, et al. CD4+ CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation. Nat Med. 2003;9(9):1144-1150.
    • (2003) Nat Med. , vol.9 , Issue.9 , pp. 1144-1150
    • Edinger, M.1    Hoffmann, P.2    Ermann, J.3
  • 128
    • 0037093217 scopus 로고    scopus 로고
    • The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality
    • Taylor PA, Lees CJ, Blazar BR. The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality. Blood. 2002;99(10): 3493-3499.
    • (2002) Blood , vol.99 , Issue.10 , pp. 3493-3499
    • Taylor, P.A.1    Lees, C.J.2    Blazar, B.R.3
  • 129
    • 27144500976 scopus 로고    scopus 로고
    • Reduced frequency of FOXP3+ CD4+CD25+ regulatory T cells in patients with chronic graft-versus-host disease
    • Zorn E, Kim HT, Lee SJ, et al. Reduced frequency of FOXP3+ CD4+CD25+ regulatory T cells in patients with chronic graft-versus-host disease. Blood. 2005;106(8):2903-2911.
    • (2005) Blood , vol.106 , Issue.8 , pp. 2903-2911
    • Zorn, E.1    Kim, H.T.2    Lee, S.J.3
  • 130
    • 32644448124 scopus 로고    scopus 로고
    • Mucosal FOXP3+ regulatory T cells are numerically deficient in acute and chronic GvHD
    • Rieger K, Loddenkemper C, Maul J, et al. Mucosal FOXP3+ regulatory T cells are numerically deficient in acute and chronic GvHD. Blood. 2006;107(4):1717-1723.
    • (2006) Blood , vol.107 , Issue.4 , pp. 1717-1723
    • Rieger, K.1    Loddenkemper, C.2    Maul, J.3
  • 131
    • 77951870520 scopus 로고    scopus 로고
    • Altered regulatory T cell homeostasis in patients with CD4+ lymphopenia following allogeneic hematopoietic stem cell transplantation
    • Matsuoka K, Kim HT, McDonough S, et al. Altered regulatory T cell homeostasis in patients with CD4+ lymphopenia following allogeneic hematopoietic stem cell transplantation. J Clin Invest. 2010;120(5):1479-1493.
    • (2010) J Clin Invest. , vol.120 , Issue.5 , pp. 1479-1493
    • Matsuoka, K.1    Kim, H.T.2    McDonough, S.3
  • 132
    • 84958191434 scopus 로고    scopus 로고
    • Unbalanced recovery of regulatory and effector T cells after allogeneic stem cell transplantation contributes to chronic GVHD
    • Alho AC, Kim HT, Chammas MJ, et al. Unbalanced recovery of regulatory and effector T cells after allogeneic stem cell transplantation contributes to chronic GVHD. Blood. 2016; 127(5):646-657.
    • (2016) Blood , vol.127 , Issue.5 , pp. 646-657
    • Alho, A.C.1    Kim, H.T.2    Chammas, M.J.3
  • 133
    • 80955167008 scopus 로고    scopus 로고
    • Low telomerase activity in CD4+ regulatory T cells in patients with severe chronic GVHD after hematopoietic stem cell transplantation
    • Kawano Y, Kim HT, Matsuoka K, et al. Low telomerase activity in CD4+ regulatory T cells in patients with severe chronic GVHD after hematopoietic stem cell transplantation. Blood. 2011;118(18):5021-5030.
    • (2011) Blood , vol.118 , Issue.18 , pp. 5021-5030
    • Kawano, Y.1    Kim, H.T.2    Matsuoka, K.3
  • 134
    • 77949900562 scopus 로고    scopus 로고
    • Dendritic cells support homeostatic expansion of foxp3+ regulatory T cells in foxp3.LuciDTR mice
    • Suffner J, Hochweller K, Kühnle MC, et al. Dendritic cells support homeostatic expansion of Foxp3+ regulatory T cells in Foxp3.LuciDTR mice. J Immunol. 2010;184(4):1810-1820.
    • (2010) J Immunol. , vol.184 , Issue.4 , pp. 1810-1820
    • Suffner, J.1    Hochweller, K.2    Kühnle, M.C.3
  • 135
    • 84886436857 scopus 로고    scopus 로고
    • CC chemokine receptor 8 potentiates donor treg survival and is critical for the prevention of murine graft-versus-host disease
    • Coghill JM, Fowler KA, West ML, et al. CC chemokine receptor 8 potentiates donor Treg survival and is critical for the prevention of murine graft-versus-host disease. Blood. 2013; 122(5):825-836.
    • (2013) Blood , vol.122 , Issue.5 , pp. 825-836
    • Coghill, J.M.1    Fowler, K.A.2    West, M.L.3
  • 136
    • 85014896129 scopus 로고    scopus 로고
    • Corruption of dendritic cell antigen presentation during acute GVHD leads to a failure of regulatory T-cell homeostasis and chronic GVHD
    • Leveque-El Mouttie L, Koyama M, Le Texier L, et al. Corruption of dendritic cell antigen presentation during acute GVHD leads to a failure of regulatory T-cell homeostasis and chronic GVHD. Blood. 2016;128(6):794-804.
    • (2016) Blood , vol.128 , Issue.6 , pp. 794-804
    • Leveque-El Mouttie, L.1    Koyama, M.2    Le Texier, L.3
  • 137
    • 74649083783 scopus 로고    scopus 로고
    • CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients
    • Blair PA, Noreña LY, Flores-Borja F, et al. CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients. Immunity. 2010;32(1): 129-140.
    • (2010) Immunity. , vol.32 , Issue.1 , pp. 129-140
    • Blair, P.A.1    Noreña, L.Y.2    Flores-Borja, F.3
  • 138
    • 78751469622 scopus 로고    scopus 로고
    • Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells
    • Iwata Y, Matsushita T, Horikawa M, et al. Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells. Blood. 2011;117(2): 530-541.
    • (2011) Blood , vol.117 , Issue.2 , pp. 530-541
    • Iwata, Y.1    Matsushita, T.2    Horikawa, M.3
  • 139
    • 84920200904 scopus 로고    scopus 로고
    • Favorable impact of natural killer cell reconstitution on chronic graft-versus-host disease and cytomegalovirus reactivation after allogeneic hematopoietic stem cell transplantation
    • Kheav VD, Busson M, Scieux C, et al. Favorable impact of natural killer cell reconstitution on chronic graft-versus-host disease and cytomegalovirus reactivation after allogeneic hematopoietic stem cell transplantation. Haematologica. 2014;99(12):1860-1867.
    • (2014) Haematologica , vol.99 , Issue.12 , pp. 1860-1867
    • Kheav, V.D.1    Busson, M.2    Scieux, C.3
  • 140
    • 60249098439 scopus 로고    scopus 로고
    • Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia
    • Cooley S, Trachtenberg E, Bergemann TL, et al. Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia. Blood. 2009;113(3): 726-732.
    • (2009) Blood , vol.113 , Issue.3 , pp. 726-732
    • Cooley, S.1    Trachtenberg, E.2    Bergemann, T.L.3
  • 142
    • 77953632374 scopus 로고    scopus 로고
    • NK cells delay allograft rejection in lymphopenic hosts by downregulating the homeostatic proliferation of CD8+ T cells
    • Zecher D, Li Q, Oberbarnscheidt MH, et al. NK cells delay allograft rejection in lymphopenic hosts by downregulating the homeostatic proliferation of CD8+ T cells. J Immunol. 2010; 184(12):6649-6657.
    • (2010) J Immunol. , vol.184 , Issue.12 , pp. 6649-6657
    • Zecher, D.1    Li, Q.2    Oberbarnscheidt, M.H.3
  • 143
    • 84882940191 scopus 로고    scopus 로고
    • Clinical relevance of natural killer cells following hematopoietic stem cell transplantation
    • Palmer JM, Rajasekaran K, Thakar MS, Malarkannan S. Clinical relevance of natural killer cells following hematopoietic stem cell transplantation. J Cancer. 2013;4(1):25-35.
    • (2013) J Cancer , vol.4 , Issue.1 , pp. 25-35
    • Palmer, J.M.1    Rajasekaran, K.2    Thakar, M.S.3    Malarkannan, S.4
  • 144
    • 80054750759 scopus 로고    scopus 로고
    • Treatment of chronic graft-versus-host disease in 2011
    • Inamoto Y, Flowers ME. Treatment of chronic graft-versus-host disease in 2011. Curr Opin Hematol. 2011;18(6):414-420.
    • (2011) Curr Opin Hematol. , vol.18 , Issue.6 , pp. 414-420
    • Inamoto, Y.1    Flowers, M.E.2
  • 145
    • 53449088758 scopus 로고    scopus 로고
    • A multicenter prospective phase 2 randomized study of extracorporeal photopheresis for treatment of chronic graft-versus-host disease
    • Flowers ME, Apperley JF, van Besien K, et al. A multicenter prospective phase 2 randomized study of extracorporeal photopheresis for treatment of chronic graft-versus-host disease. Blood. 2008;112(7):2667-2674.
    • (2008) Blood , vol.112 , Issue.7 , pp. 2667-2674
    • Flowers, M.E.1    Apperley, J.F.2    Van Besien, K.3
  • 146
    • 84904899365 scopus 로고    scopus 로고
    • HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse
    • Martelli MF, Di Ianni M, Ruggeri L, et al. HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse. Blood. 2014; 124(4):638-644.
    • (2014) Blood , vol.124 , Issue.4 , pp. 638-644
    • Martelli, M.F.1    Di Ianni, M.2    Ruggeri, L.3
  • 147
    • 84961187570 scopus 로고    scopus 로고
    • Haploidentical bone marrow and stem cell transplantation: Experience with posttransplantation cyclophosphamide
    • Robinson TM, O'Donnell PV, Fuchs EJ, Luznik L. Haploidentical bone marrow and stem cell transplantation: experience with posttransplantation cyclophosphamide. Semin Hematol. 2016;53(2):90-97.
    • (2016) Semin Hematol. , vol.53 , Issue.2 , pp. 90-97
    • Robinson, T.M.1    O'Donnell, P.V.2    Fuchs, E.J.3    Luznik, L.4
  • 148
    • 80855128779 scopus 로고    scopus 로고
    • Prevention of GVHD while sparing GVL effect by targeting th1 and th17 transcription factor T-bet and RORγt in mice
    • Yu Y, Wang D, Liu C, et al. Prevention of GVHD while sparing GVL effect by targeting Th1 and Th17 transcription factor T-bet and RORγt in mice. Blood. 2011;118(18):5011-5020.
    • (2011) Blood , vol.118 , Issue.18 , pp. 5011-5020
    • Yu, Y.1    Wang, D.2    Liu, C.3
  • 149
    • 0037026001 scopus 로고    scopus 로고
    • CD4(+)CD25(+) immunoregulatory T cells: New therapeutics for graft-versus-host disease
    • Cohen JL, Trenado A, Vasey D, Klatzmann D, Salomon BL. CD4(+)CD25(+) immunoregulatory T cells: new therapeutics for graft-versus-host disease. J Exp Med. 2002;196(3): 401-406.
    • (2002) J Exp Med. , vol.196 , Issue.3 , pp. 401-406
    • Cohen, J.L.1    Trenado, A.2    Vasey, D.3    Klatzmann, D.4    Salomon, B.L.5
  • 150
    • 0037025943 scopus 로고    scopus 로고
    • Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation
    • Hoffmann P, Ermann J, Edinger M, Fathman CG, Strober S. Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation. J Exp Med. 2002; 196(3):389-399.
    • (2002) J Exp Med. , vol.196 , Issue.3 , pp. 389-399
    • Hoffmann, P.1    Ermann, J.2    Edinger, M.3    Fathman, C.G.4    Strober, S.5
  • 151
    • 79953809817 scopus 로고    scopus 로고
    • Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation
    • Di Ianni M, Falzetti F, Carotti A, et al. Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation. Blood. 2011;117(14):3921-3928.
    • (2011) Blood , vol.117 , Issue.14 , pp. 3921-3928
    • Di Ianni, M.1    Falzetti, F.2    Carotti, A.3
  • 152
    • 84960337895 scopus 로고    scopus 로고
    • Umbilical cord blood-derived T regulatory cells to prevent GVHD: Kinetics, toxicity profile, and clinical effect
    • Brunstein CG, Miller JS, McKenna DH, et al. Umbilical cord blood-derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect. Blood. 2016;127(8):1044-1051.
    • (2016) Blood , vol.127 , Issue.8 , pp. 1044-1051
    • Brunstein, C.G.1    Miller, J.S.2    McKenna, D.H.3
  • 153
    • 85009127759 scopus 로고    scopus 로고
    • Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5-dependent manner
    • McDonald-Hyman C, Flynn R, Panoskaltsis-Mortari A, et al. Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5-dependent manner. Blood. 2016;128(7):1013-1017.
    • (2016) Blood , vol.128 , Issue.7 , pp. 1013-1017
    • McDonald-Hyman, C.1    Flynn, R.2    Panoskaltsis-Mortari, A.3
  • 154
    • 84977609937 scopus 로고    scopus 로고
    • Efficacy, durability, and response predictors of low-dose interleukin-2 therapy for chronic graft-versus-host disease
    • Koreth J, Kim HT, Jones KT, et al. Efficacy, durability, and response predictors of low-dose interleukin-2 therapy for chronic graft-versus-host disease. Blood. 2016;128(1):130-137.
    • (2016) Blood , vol.128 , Issue.1 , pp. 130-137
    • Koreth, J.1    Kim, H.T.2    Jones, K.T.3
  • 155
    • 82555168440 scopus 로고    scopus 로고
    • Interleukin-2 and regulatory T cells in graft-versus-host disease
    • Koreth J, Matsuoka K, Kim HT, et al. Interleukin-2 and regulatory T cells in graft-versus-host disease. N Engl J Med. 2011;365(22): 2055-2066.
    • (2011) N Engl J Med. , vol.365 , Issue.22 , pp. 2055-2066
    • Koreth, J.1    Matsuoka, K.2    Kim, H.T.3
  • 156
    • 84886855920 scopus 로고    scopus 로고
    • Rituximab prophylaxis prevents corticosteroid-requiring chronic GVHD after allogeneic peripheral blood stem cell transplantation: Results of a phase 2 trial
    • Cutler C, Kim HT, Bindra B, et al. Rituximab prophylaxis prevents corticosteroid-requiring chronic GVHD after allogeneic peripheral blood stem cell transplantation: results of a phase 2 trial. Blood. 2013;122(8):1510-1517.
    • (2013) Blood , vol.122 , Issue.8 , pp. 1510-1517
    • Cutler, C.1    Kim, H.T.2    Bindra, B.3
  • 157
    • 84958983532 scopus 로고    scopus 로고
    • A randomized phase II crossover study of imatinib or rituximab for cutaneous sclerosis after hematopoietic cell transplantation
    • Arai S, Pidala J, Pusic I, et al. A randomized phase II crossover study of imatinib or rituximab for cutaneous sclerosis after hematopoietic cell transplantation. Clin Cancer Res. 2016;22(2): 319-327.
    • (2016) Clin Cancer Res. , vol.22 , Issue.2 , pp. 319-327
    • Arai, S.1    Pidala, J.2    Pusic, I.3
  • 158
    • 84902581112 scopus 로고    scopus 로고
    • Activity of therapeutic JAK 1/2 blockade in graft-versus-host disease
    • Spoerl S, Mathew NR, Bscheider M, et al. Activity of therapeutic JAK 1/2 blockade in graft-versus-host disease. Blood. 2014;123(24): 3832-3842.
    • (2014) Blood , vol.123 , Issue.24 , pp. 3832-3842
    • Spoerl, S.1    Mathew, N.R.2    Bscheider, M.3
  • 159
    • 84943582032 scopus 로고    scopus 로고
    • Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: A multicenter survey
    • Zeiser R, Burchert A, Lengerke C, et al. Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multicenter survey. Leukemia. 2015;29(10):2062-2068.
    • (2015) Leukemia , vol.29 , Issue.10 , pp. 2062-2068
    • Zeiser, R.1    Burchert, A.2    Lengerke, C.3
  • 160
    • 84907013113 scopus 로고    scopus 로고
    • Treatment of chronic graft-versus-host disease with bortezomib
    • Pai CC, Chen M, Mirsoian A, et al. Treatment of chronic graft-versus-host disease with bortezomib. Blood. 2014;124(10):1677-1688.
    • (2014) Blood , vol.124 , Issue.10 , pp. 1677-1688
    • Pai, C.C.1    Chen, M.2    Mirsoian, A.3
  • 161
    • 24744447794 scopus 로고    scopus 로고
    • TGF-beta in allogeneic stem cell transplantation: Friend or foe?
    • Banovic T, MacDonald KP, Morris ES, et al. TGF-beta in allogeneic stem cell transplantation: friend or foe? Blood. 2005;106(6):2206-2214.
    • (2005) Blood , vol.106 , Issue.6 , pp. 2206-2214
    • Banovic, T.1    MacDonald, K.P.2    Morris, E.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.