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Volumn 36, Issue 1, 2001, Pages 63-74

Prodrugs of butyric acid. Novel derivatives possessing increased aqueous solubility and potential for treating cancer and blood diseases

(12) Nudelman, Abraham a Gnizi, Elisheva a Katz, Yifat a Azulai, Revital a Cohen Ohana, Mirit a Zhuk, Regina a Sampson, Sanford R a Langzam, Leah a Fibach, Eitan b Prus, Eugenia b Pugach, Victoria c Rephaeli, Ada c

a BAR ILAN UNIVERSITY (Israel)

b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER (Israel)

c TEL AVIV UNIVERSITY (Israel)

Author keywords

Anticancer; Butyric acid; Prodrugs; Water solubility

Indexed keywords

ACETALDEHYDE; AN 10; BUTYLIDENE DIBUTYRATE; BUTYRIC ACID 1 (DIETHOXYPHOSPHORYLOXY)ETHYL ESTER; BUTYRIC ACID DERIVATIVE; BUTYRIC ACID DIETHOXYPHOSPHORYLOXYMETHYL ESTER; FORMALDEHYDE; NICOTINIC ACID 1 BUTYRYLOXYETHYL ESTER; NICOTINIC ACID BUTYROYLOXYMETHYL ESTER; PENTANEDIOIC ACID MONO(1 BUTYRYLOXYETHYL)ESTER; PENTANEDIOIC ACID MONOBUTYRYLOXYMETHYL ESTER; PIVALOYLOXYMETHYL BUTYRATE; PRODRUG; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; BLOOD DISEASE; CANCER THERAPY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG POTENCY; DRUG SCREENING; DRUG SOLUBILITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; LD 50;

ANIMALS; APOPTOSIS; BUTYRIC ACID; CELL DIVISION; FEMALE; HEMOGLOBINS; HL-60 CELLS; HUMANS; LETHAL DOSE 50; MALE; MICE; MICE, INBRED BALB C; NEOPLASMS; PRODRUGS; SOLUBILITY; TUMOR CELLS, CULTURED;

EID: 0035111343 PISSN: 02235234 EISSN: None Source Type: Journal
DOI: 10.1016/S0223-5234(00)01199-5 Document Type: Article

Times cited : (72)

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