-
1
-
-
0033536288
-
The beta-thalassemias
-
Olivieri NF. The beta-thalassemias. N Engl J Med. 1999;341:99-109.
-
(1999)
N Engl J Med
, vol.341
, pp. 99-109
-
-
Olivieri, N.F.1
-
2
-
-
0034772589
-
Pharmacological induction of fetal hemoglobin in sickle cell disease and beta-thalassemia
-
Atweh GF, Loukopoulos D. Pharmacological induction of fetal hemoglobin in sickle cell disease and beta-thalassemia. Semin Hematol. 2001;38:367-373.
-
(2001)
Semin Hematol
, vol.38
, pp. 367-373
-
-
Atweh, G.F.1
Loukopoulos, D.2
-
3
-
-
0035003466
-
Advances in experimental treatment of beta-thalassaemia
-
Rodgers GP, Sauntharajah Y. Advances in experimental treatment of beta-thalassaemia. Exp Opin Invest Drugs. 2001;10:925-934.
-
(2001)
Exp Opin Invest Drugs
, vol.10
, pp. 925-934
-
-
Rodgers, G.P.1
Sauntharajah, Y.2
-
4
-
-
0027078611
-
A short-term trial of butyrate to stimulate fetal-globin-gene expression in the beta-globin disorders
-
Perrine SP, Ginder GD, Faller DV, et al. A short-term trial of butyrate to stimulate fetal-globin-gene expression in the beta-globin disorders. N Engl J Med. 1993;328:81-86.
-
(1993)
N Engl J Med
, vol.328
, pp. 81-86
-
-
Perrine, S.P.1
Ginder, G.D.2
Faller, D.V.3
-
6
-
-
0028303870
-
Induction of fetal hemoglobin production in subjects with sickle cell anemia by oral sodium phenylbutyrate
-
Dover GJ, Brusilow S, Charache S. Induction of fetal hemoglobin production in subjects with sickle cell anemia by oral sodium phenylbutyrate. Blood. 1994;84:339-343.
-
(1994)
Blood
, vol.84
, pp. 339-343
-
-
Dover, G.J.1
Brusilow, S.2
Charache, S.3
-
7
-
-
0029032965
-
Extended therapy with intravenous arginine butyrate in patients with beta-hemoglobinopathies
-
Sher GD, Ginder GD, Little J, Yang S, Dover GJ, Olivieri NF. Extended therapy with intravenous arginine butyrate in patients with beta-hemoglobinopathies. N Engl J Med. 1995;332:1606-1610.
-
(1995)
N Engl J Med
, vol.332
, pp. 1606-1610
-
-
Sher, G.D.1
Ginder, G.D.2
Little, J.3
Yang, S.4
Dover, G.J.5
Olivieri, N.F.6
-
8
-
-
0034670051
-
Oral isobutyramide reduces transfusion requirements in some patients with homozygous beta-thalassemia
-
Reich S, Bührer C, Henze G, et al. Oral isobutyramide reduces transfusion requirements in some patients with homozygous beta-thalassemia. Blood. 2000;96:3357-3363.
-
(2000)
Blood
, vol.96
, pp. 3357-3363
-
-
Reich, S.1
Bührer, C.2
Henze, G.3
-
9
-
-
0018371969
-
Different accessibilities in chromatin to histone acetylase
-
Cousens LS, Gallwitz D, Alberts BM. Different accessibilities in chromatin to histone acetylase. J Biol Chem. 1978;254:1716-1723.
-
(1978)
J Biol Chem
, vol.254
, pp. 1716-1723
-
-
Cousens, L.S.1
Gallwitz, D.2
Alberts, B.M.3
-
10
-
-
0017886958
-
Sodium butyrate inhibits histone deacetylation in cultured cells
-
Candido EMP, Reeves R, Davie JR. Sodium butyrate inhibits histone deacetylation in cultured cells. Cell. 1978;14:105-113.
-
(1978)
Cell
, vol.14
, pp. 105-113
-
-
Candido, E.M.P.1
Reeves, R.2
Davie, J.R.3
-
11
-
-
0020493694
-
Acetylation of histones in nucleosomes
-
Doenecke D, Gallwitz D. Acetylation of histones in nucleosomes. Mol Cell Biochem. 1982;44:113-128.
-
(1982)
Mol Cell Biochem
, vol.44
, pp. 113-128
-
-
Doenecke, D.1
Gallwitz, D.2
-
12
-
-
0030923438
-
Induction of gamma-globin by histone deacetylase inhibitors
-
McCaffrey PG, Newsome DA, Fibach E, Yoshida M, Su MSS. Induction of gamma-globin by histone deacetylase inhibitors. Blood. 1997;5:2075-2083.
-
(1997)
Blood
, vol.5
, pp. 2075-2083
-
-
McCaffrey, P.G.1
Newsome, D.A.2
Fibach, E.3
Yoshida, M.4
Su, M.S.S.5
-
13
-
-
0023195737
-
Effects of trichostatins on differentiation of murine erythroleukemia cells
-
Yoshida M, Nomura S, Beppu T. Effects of trichostatins on differentiation of murine erythroleukemia cells. Cancer Res. 1987;47:3688-3691.
-
(1987)
Cancer Res
, vol.47
, pp. 3688-3691
-
-
Yoshida, M.1
Nomura, S.2
Beppu, T.3
-
14
-
-
0031587042
-
Transcriptional regulation of the human replacement histone gene H3.3B
-
Witt O, Albig W, Doenecke D. Transcriptional regulation of the human replacement histone gene H3.3B. FEBS Lett. 1997;408:255-260.
-
(1997)
FEBS Lett
, vol.408
, pp. 255-260
-
-
Witt, O.1
Albig, W.2
Doenecke, D.3
-
15
-
-
0024996768
-
Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A
-
Yoshida M, Kijima M, Akita M, Beppu T. Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A. J Biol Chem. 1990;265:17174-17179.
-
(1990)
J Biol Chem
, vol.265
, pp. 17174-17179
-
-
Yoshida, M.1
Kijima, M.2
Akita, M.3
Beppu, T.4
-
16
-
-
0034326799
-
Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21 WAF1/Cip1 and gelsolin
-
Han JW, Ahn SH, Park SH, et al. Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21 WAF1/Cip1 and gelsolin. Cancer Res. 2000;60:6068-6074.
-
(2000)
Cancer Res
, vol.60
, pp. 6068-6074
-
-
Han, J.W.1
Ahn, S.H.2
Park, S.H.3
-
17
-
-
0034176006
-
Butyrate induced erythroid differentiation of human K562 cells involves inhibition of ERK and activation of p38 MAP kinase-pathways
-
Witt O, Sand K, Pekrun A. Butyrate induced erythroid differentiation of human K562 cells involves inhibition of ERK and activation of p38 MAP kinase-pathways. Blood. 2000;95:2391-2396.
-
(2000)
Blood
, vol.95
, pp. 2391-2396
-
-
Witt, O.1
Sand, K.2
Pekrun, A.3
-
18
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
Lee JC, Laydon JT, McDonnell PC, et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature. 1994;372:739-746.
-
(1994)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
Laydon, J.T.2
McDonnell, P.C.3
-
19
-
-
0028988138
-
SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
-
Cuenda A, Rouse J, Doza YN, et al. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett. 1995;364:229-233.
-
(1995)
FEBS Lett
, vol.364
, pp. 229-233
-
-
Cuenda, A.1
Rouse, J.2
Doza, Y.N.3
-
20
-
-
0030426902
-
Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function
-
Badger AM, Bradbeer JN, Votta B, Lee JC, Adams JL, Griswold DE. Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function. J Pharmacol Exp Ther. 1996;279:1453-1461.
-
(1996)
J Pharmacol Exp Ther
, vol.279
, pp. 1453-1461
-
-
Badger, A.M.1
Bradbeer, J.N.2
Votta, B.3
Lee, J.C.4
Adams, J.L.5
Griswold, D.E.6
-
21
-
-
14444279192
-
Identification of a novel inhibitor of mitogen activated protein kinase kinase
-
Favata M, Horiuchi KY, Manos EJ, et al. Identification of a novel inhibitor of mitogen activated protein kinase kinase. J Biol Chem. 1998;273:18623-18632.
-
(1998)
J Biol Chem
, vol.273
, pp. 18623-18632
-
-
Favata, M.1
Horiuchi, K.Y.2
Manos, E.J.3
-
22
-
-
0032558998
-
Structure and function of the core histone N-termini: More than meets the eye
-
Hansen JC, Tse C, Wolffe AP. Structure and function of the core histone N-termini: more than meets the eye. Biochemistry. 1998;37:17637-17641.
-
(1998)
Biochemistry
, vol.37
, pp. 17637-17641
-
-
Hansen, J.C.1
Tse, C.2
Wolffe, A.P.3
-
23
-
-
7344238492
-
Histone acetylation is required to maintain the unfolded nucleosome structure associated with transcribing DNA
-
Walia H, Chen HY, Sun JM, Holth LT, Davie JR. Histone acetylation is required to maintain the unfolded nucleosome structure associated with transcribing DNA. J Biol Chem. 1998;273:14516-14522.
-
(1998)
J Biol Chem
, vol.273
, pp. 14516-14522
-
-
Walia, H.1
Chen, H.Y.2
Sun, J.M.3
Holth, L.T.4
Davie, J.R.5
-
24
-
-
0032525139
-
Histone acetylation facilitates RNA polymerase II transcription of the Drosophila hsp26 gene in chromatin
-
Nightinghale KP, Wellinger RE, Sogo JM, Becker PB. Histone acetylation facilitates RNA polymerase II transcription of the Drosophila hsp26 gene in chromatin. EMBO J. 1998;17:2865-2876.
-
(1998)
EMBO J
, vol.17
, pp. 2865-2876
-
-
Nightinghale, K.P.1
Wellinger, R.E.2
Sogo, J.M.3
Becker, P.B.4
-
25
-
-
0031876314
-
Disruption of higher order folding by core histone acetylation dramatically enhances transcription of nucleosomal arrays by RNA polymerase III
-
Tse C, Sera T, Wolffe AP, Hansen JC. Disruption of higher order folding by core histone acetylation dramatically enhances transcription of nucleosomal arrays by RNA polymerase III. Mol Cell Biol. 1998;18:4629-4638.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 4629-4638
-
-
Tse, C.1
Sera, T.2
Wolffe, A.P.3
Hansen, J.C.4
-
26
-
-
0034687789
-
Developmentally dynamic histone acetylation pattern of a tissue-specific chromatin domain
-
Forsberg EC, Downs KM, Christensen HM, Im H, Nuzzi PA, Bresnick EH. Developmentally dynamic histone acetylation pattern of a tissue-specific chromatin domain. Proc Natl Acad Sci U S A. 2000;97:14494-14499.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 14494-14499
-
-
Forsberg, E.C.1
Downs, K.M.2
Christensen, H.M.3
Im, H.4
Nuzzi, P.A.5
Bresnick, E.H.6
-
27
-
-
0034141523
-
Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells
-
Smith RD, Li J, Noguchi CT, Schechter AN. Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells. Blood. 2000;95:863-869
-
(2000)
Blood
, vol.95
, pp. 863-869
-
-
Smith, R.D.1
Li, J.2
Noguchi, C.T.3
Schechter, A.N.4
-
28
-
-
10544250252
-
Apicidin: A novel antiprotozoal agent that inhibits parasite histone deacetylase
-
Darkin-Rattray SJ, Gurnett AM, Myers RW, et al. Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase. Proc Natl Acad Sci U S A. 1996;93:13143-13147.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 13143-13147
-
-
Darkin-Rattray, S.J.1
Gurnett, A.M.2
Myers, R.W.3
-
29
-
-
0001811191
-
Histone deacetylase as a new target for cancer chemotherapy
-
Yoshida M, Furumai R, Nishiyama M, Komatsu Y, Nishino N, Horinouchi S. Histone deacetylase as a new target for cancer chemotherapy. Cancer Chemother Pharmacol. 2001;48(suppl 1):S20-S26.
-
(2001)
Cancer Chemother Pharmacol
, vol.48
, Issue.SUPPL. 1
-
-
Yoshida, M.1
Furumai, R.2
Nishiyama, M.3
Komatsu, Y.4
Nishino, N.5
Horinouchi, S.6
-
30
-
-
0031900740
-
Signal transduction through MAP kinase cascades
-
Lewis TS, Shapiro PS, Ahn NG. Signal transduction through MAP kinase cascades. Adv Cancer Res. 1998;74:49-139.
-
(1998)
Adv Cancer Res
, vol.74
, pp. 49-139
-
-
Lewis, T.S.1
Shapiro, P.S.2
Ahn, N.G.3
-
31
-
-
0029011218
-
The MAPK signaling cascade
-
Seger R, Krebs EG. The MAPK signaling cascade. FASEB J. 1995;9:726-735.
-
(1995)
FASEB J
, vol.9
, pp. 726-735
-
-
Seger, R.1
Krebs, E.G.2
-
32
-
-
0035841014
-
Tumor cell differentiation by butyrate and environmental stress
-
Witt O, Schulze S, Kanbach K, Roth C, Pekrun A. Tumor cell differentiation by butyrate and environmental stress. Cancer Lett. 2001;171:173-182.
-
(2001)
Cancer Lett
, vol.171
, pp. 173-182
-
-
Witt, O.1
Schulze, S.2
Kanbach, K.3
Roth, C.4
Pekrun, A.5
-
33
-
-
0032530921
-
Activation of p38 MAP kinase and JNK but not ERK is required for erythropoietin-induced erythroid differentiation
-
Nagata Y, Takahashi N, Davis RJ, Todokoro K. Activation of p38 MAP kinase and JNK but not ERK is required for erythropoietin-induced erythroid differentiation. Blood. 1998;92:1859-1869.
-
(1998)
Blood
, vol.92
, pp. 1859-1869
-
-
Nagata, Y.1
Takahashi, N.2
Davis, R.J.3
Todokoro, K.4
-
34
-
-
0033178564
-
Requirement of activation of JNK and p38 for environmental stress-induced erythroid differentiation and apoptosis and of inhibition of ERK for apoptosis
-
Nagata Y, Todokoro K. Requirement of activation of JNK and p38 for environmental stress-induced erythroid differentiation and apoptosis and of inhibition of ERK for apoptosis. Blood. 1999;94:853-863.
-
(1999)
Blood
, vol.94
, pp. 853-863
-
-
Nagata, Y.1
Todokoro, K.2
|