-
1
-
-
0037822085
-
Histone deacetylase inhibitors in cancer therapy
-
RR Rosato S Grant 2003 Histone deacetylase inhibitors in cancer therapy Cancer Biol Ther 2 30 37
-
(2003)
Cancer Biol Ther
, vol.2
, pp. 30-37
-
-
Rosato, R.R.1
Grant, S.2
-
2
-
-
0033819869
-
Prodrugs of butyric acid from the bench to bedside
-
doi:10.1002/1098-2299(200007/08)50:3/4<379::AID-DDR20>3.0.CO;2-8
-
Rephaeli A, Zhuk R, Nudelman A (2000) Prodrugs of butyric acid from the bench to bedside. Drug Dev Res 50:379-391. doi:10.1002/1098-2299(200007/08)50:3/ 4<379::AID-DDR20>3.0.CO;2-8
-
(2000)
Drug Dev Res
, vol.50
, pp. 379-391
-
-
Rephaeli, A.1
Zhuk, R.2
Nudelman, A.3
-
3
-
-
0036839093
-
The histone deacetylase inhibitor AN-9 has selective toxicity to acute leukemia and drug-resistant primary leukemia and cancer cell lines
-
10.1182/blood-2002-02-0567
-
A Batova L Shao MB Diccianni 2002 The histone deacetylase inhibitor AN-9 has selective toxicity to acute leukemia and drug-resistant primary leukemia and cancer cell lines Blood 100 3319 3324 10.1182/blood-2002-02-0567
-
(2002)
Blood
, vol.100
, pp. 3319-3324
-
-
Batova, A.1
Shao, L.2
Diccianni, M.B.3
-
4
-
-
0035111343
-
Prodrugs of butyric acid (lll) novel derivatives possessing increased aqueous solubility and potential for treating cancer and blood diseases
-
10.1016/S0223-5234(00)01199-5
-
A Nudelman E Gnizi Y Katz 2001 Prodrugs of butyric acid (lll) novel derivatives possessing increased aqueous solubility and potential for treating cancer and blood diseases Eur J Med Chem 36 63 74 10.1016/S0223-5234(00)01199-5
-
(2001)
Eur J Med Chem
, vol.36
, pp. 63-74
-
-
Nudelman, A.1
Gnizi, E.2
Katz, Y.3
-
5
-
-
13944275513
-
The role of intracellularly released formaldehyde and butyric acid, in the anticancer activity of acyloxyalkyl esters
-
10.1021/jm049428p
-
A Nudelman I Levovich SM Cutts 2005 The role of intracellularly released formaldehyde and butyric acid, in the anticancer activity of acyloxyalkyl esters J Med Chem 48 1042 1054 10.1021/jm049428p
-
(2005)
J Med Chem
, vol.48
, pp. 1042-1054
-
-
Nudelman, A.1
Levovich, I.2
Cutts, S.M.3
-
6
-
-
33745021853
-
The selectivity and anti-metastatic activity of oral bioavailable butyric acid prodrugs
-
10.1007/s10637-006-6213-1
-
A Rephaeli M Entin-Meer D Angel 2006 The selectivity and anti-metastatic activity of oral bioavailable butyric acid prodrugs Invest New Drugs 24 383 392 10.1007/s10637-006-6213-1
-
(2006)
Invest New Drugs
, vol.24
, pp. 383-392
-
-
Rephaeli, A.1
Entin-Meer, M.2
Angel, D.3
-
7
-
-
33748166657
-
Mode of interaction between the HDAC inhibitor AN-7 and doxorubicin in MCF-7 and resistant MCF-7/Dx cell lines
-
10.1007/s00432-006-0116-6
-
D Engel A Nudelman I Levovich 2006 Mode of interaction between the HDAC inhibitor AN-7 and doxorubicin in MCF-7 and resistant MCF-7/Dx cell lines J Cancer Res Clin Oncol 132 673 683 10.1007/s00432-006-0116-6
-
(2006)
J Cancer Res Clin Oncol
, vol.132
, pp. 673-683
-
-
Engel, D.1
Nudelman, A.2
Levovich, I.3
-
8
-
-
23844509864
-
Formaldehyde-releasing prodrugs in combination with adriamycin can overcome cellular drug resistance
-
SM Cutts A Nudelman V Pillay 2005 Formaldehyde-releasing prodrugs in combination with adriamycin can overcome cellular drug resistance Oncol Res 15 199 213
-
(2005)
Oncol Res
, vol.15
, pp. 199-213
-
-
Cutts, S.M.1
Nudelman, A.2
Pillay, V.3
-
9
-
-
30344476415
-
Butyric acid prodrugs are histone deacetylase inhibitors that demonstrate anti-neoplastic activity and radiosensitizing capacity in the treatment of malignant gliomas
-
10.1158/1535-7163.MCT-05-0087
-
M Entin-Meer A Rephaeli X Yang 2005 Butyric acid prodrugs are histone deacetylase inhibitors that demonstrate anti-neoplastic activity and radiosensitizing capacity in the treatment of malignant gliomas Mol Cancer Ther 4 1952 1961 10.1158/1535-7163.MCT-05-0087
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 1952-1961
-
-
Entin-Meer, M.1
Rephaeli, A.2
Yang, X.3
-
10
-
-
34147206651
-
In vivo efficacy of a novel histone deacetylase inhibitor in combination with radiation for the treatment of gliomas
-
10.1215/15228517-2006-032
-
M Entin-Meer X Yang SR Vandenberg 2007 In vivo efficacy of a novel histone deacetylase inhibitor in combination with radiation for the treatment of gliomas Neurooncology 9 82 88 10.1215/15228517-2006-032
-
(2007)
Neurooncology
, vol.9
, pp. 82-88
-
-
Entin-Meer, M.1
Yang, X.2
Vandenberg, S.R.3
-
11
-
-
22044435505
-
In vivo and in vitro antitumor activity of butyroyloxymethyl-diethyl phosphate (AN-7), a histone deacetylase inhibitor, in human prostate cancer
-
10.1002/ijc.21030
-
A Rephaeli D Blank-Porat N Tarasenko 2005 In vivo and in vitro antitumor activity of butyroyloxymethyl-diethyl phosphate (AN-7), a histone deacetylase inhibitor, in human prostate cancer Int J Cancer 116 226 235 10.1002/ijc.21030
-
(2005)
Int J Cancer
, vol.116
, pp. 226-235
-
-
Rephaeli, A.1
Blank-Porat, D.2
Tarasenko, N.3
-
12
-
-
34548287904
-
The anticancer prodrugs of butyric acid AN-7 and AN-9, possess antiangiogenic properties
-
10.1016/j.canlet.2007.05.011
-
D Blank-Porat T Gruss-Fischer N Tarasenko 2007 The anticancer prodrugs of butyric acid AN-7 and AN-9, possess antiangiogenic properties Cancer Lett 256 39 48 10.1016/j.canlet.2007.05.011
-
(2007)
Cancer Lett
, vol.256
, pp. 39-48
-
-
Blank-Porat, D.1
Gruss-Fischer, T.2
Tarasenko, N.3
-
13
-
-
34249829254
-
Anticancer prodrugs of butyric acid and formaldehyde protect against doxorubicine-induced cardiotoxicity
-
10.1038/sj.bjc.6603781
-
A Rephaeli S Waks-Yona A Nudelman 2007 Anticancer prodrugs of butyric acid and formaldehyde protect against doxorubicine-induced cardiotoxicity Br J Cancer 96 1667 1674 10.1038/sj.bjc.6603781
-
(2007)
Br J Cancer
, vol.96
, pp. 1667-1674
-
-
Rephaeli, A.1
Waks-Yona, S.2
Nudelman, A.3
-
14
-
-
0035992310
-
A phase I study of pivaloyloxymethyl butyrate, a prodrug of the differentiating agent butyric acid, in patients with advanced solid malignancies
-
A Patnaik EK Rowinsky MA Villalona 2002 A phase I study of pivaloyloxymethyl butyrate, a prodrug of the differentiating agent butyric acid, in patients with advanced solid malignancies Clin Cancer Res 8 2142 2148
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2142-2148
-
-
Patnaik, A.1
Rowinsky, E.K.2
Villalona, M.A.3
-
15
-
-
3843151628
-
Phase II trial of the histone deacetylase inhibitor pivaloyloxymethyl butyrate (Pivanex, AN-9) in advanced non-small cell lung cancer
-
10.1016/j.lungcan.2004.03.002
-
T Reid F Valone W Lipera 2004 Phase II trial of the histone deacetylase inhibitor pivaloyloxymethyl butyrate (Pivanex, AN-9) in advanced non-small cell lung cancer Lung Cancer 45 381 386 10.1016/j.lungcan.2004.03.002
-
(2004)
Lung Cancer
, vol.45
, pp. 381-386
-
-
Reid, T.1
Valone, F.2
Lipera, W.3
-
16
-
-
0026048664
-
Carcinoembryonic antigen gene family: Molecular biology and clinical perspectives
-
10.1002/jcla.1860050510
-
J Thompson F Grunert W Zimmermann 1991 Carcinoembryonic antigen gene family: molecular biology and clinical perspectives J Clin Lab Anal 5 344 366 10.1002/jcla.1860050510
-
(1991)
J Clin Lab Anal
, vol.5
, pp. 344-366
-
-
Thompson, J.1
Grunert, F.2
Zimmermann, W.3
-
17
-
-
0036229850
-
Comparison of methods of microvascular staining and quantification in prostate carcinoma: Relevance to prognosis
-
10.1034/j.1600-0463.2002.100209.x
-
BV Offersen M Borre FB Sørensen 2002 Comparison of methods of microvascular staining and quantification in prostate carcinoma: relevance to prognosis APMIS 110 177 185 10.1034/j.1600-0463.2002.100209.x
-
(2002)
APMIS
, vol.110
, pp. 177-185
-
-
Offersen, B.V.1
Borre, M.2
Sørensen, F.B.3
-
18
-
-
0031053759
-
Biological roles fibroblast growth factor-2
-
10.1210/er.18.1.26
-
A Bikfalvi S Klein G Pintucci 1997 Biological roles fibroblast growth factor-2 Endocr Rev 18 26 45 10.1210/er.18.1.26
-
(1997)
Endocr Rev
, vol.18
, pp. 26-45
-
-
Bikfalvi, A.1
Klein, S.2
Pintucci, G.3
-
19
-
-
0033984235
-
The Ki-67 protein: From the known and the unknown
-
10.1002/(SICI)1097-4652(200003)182:3<311::AID-JCP1>3.0.CO;2-9
-
T Scholzen J Gerdes 2000 The Ki-67 protein: from the known and the unknown J Cell Physiol 182 311 322 10.1002/(SICI)1097-4652(200003)182:3<311:: AID-JCP1>3.0.CO;2-9
-
(2000)
J Cell Physiol
, vol.182
, pp. 311-322
-
-
Scholzen, T.1
Gerdes, J.2
-
20
-
-
0035058011
-
Correlation of immunohistochemical p53 labeling index with inhibition rate in chemosensitivity test in gastric and colon cancer
-
N Hosaka Y Ichikawa T Ishikawa 2001 Correlation of immunohistochemical p53 labeling index with inhibition rate in chemosensitivity test in gastric and colon cancer Anticancer Res 21 229 235
-
(2001)
Anticancer Res
, vol.21
, pp. 229-235
-
-
Hosaka, N.1
Ichikawa, Y.2
Ishikawa, T.3
-
21
-
-
4644370374
-
Signaling via the hypoxia-inducible factor-1 alpha requires multiple posttranslational modifications
-
10.1016/j.cellsig.2004.04.010
-
C Brahimi-Horn N Mazure J Pouysségur 2005 Signaling via the hypoxia-inducible factor-1 alpha requires multiple posttranslational modifications Cell Signal 17 1 9 10.1016/j.cellsig.2004.04.010
-
(2005)
Cell Signal
, vol.17
, pp. 1-9
-
-
Brahimi-Horn, C.1
Mazure, N.2
Pouysségur, J.3
-
22
-
-
0033982379
-
Matrix metalloproteinases in tumor invasion
-
10.1007/s000180050495
-
N Johansson M Ahonen M Kähäri 2000 Matrix metalloproteinases in tumor invasion CMLS (Cell Mol Life Sci) 57 5 15 10.1007/s000180050495
-
(2000)
CMLS (Cell Mol Life Sci)
, vol.57
, pp. 5-15
-
-
Johansson, N.1
Ahonen, M.2
Kähäri, M.3
-
23
-
-
0027516026
-
Tissue inhibitor of metalloproteinase-1 is a negative regulator of the metastatic ability of a human gastric cancer cell-line, Kkls, in the chic-embryo
-
Y Tsuchiy H Sato Y Endo 1993 Tissue inhibitor of metalloproteinase-1 is a negative regulator of the metastatic ability of a human gastric cancer cell-line, Kkls, in the chic-embryo Cancer Res 53 1397 1402
-
(1993)
Cancer Res
, vol.53
, pp. 1397-1402
-
-
Tsuchiy, Y.1
Sato, H.2
Endo, Y.3
-
24
-
-
0029998873
-
Inhibition of metastasis in human gastric cancer cells transfected with tissue inhibitor of metalloproteinase 1 gene in nude mice
-
M Watanabe Y Takahashi T Ohta 1996 Inhibition of metastasis in human gastric cancer cells transfected with tissue inhibitor of metalloproteinase 1 gene in nude mice Cancer 77 1676 1680
-
(1996)
Cancer
, vol.77
, pp. 1676-1680
-
-
Watanabe, M.1
Takahashi, Y.2
Ohta, T.3
-
25
-
-
0035048449
-
Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes
-
10.1038/86507
-
MS Kim HJ Kwon YM Lee 2001 Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes Nat Med 7 437 443 10.1038/86507
-
(2001)
Nat Med
, vol.7
, pp. 437-443
-
-
Kim, M.S.1
Kwon, H.J.2
Lee, Y.M.3
-
26
-
-
1542389542
-
Molecular and genetic prognostic factors of prostate cancer
-
10.1007/s00345-003-0362-z
-
A Chakravarti GG Zhai 2003 Molecular and genetic prognostic factors of prostate cancer World J Urol 21 265 274 10.1007/s00345-003-0362-z
-
(2003)
World J Urol
, vol.21
, pp. 265-274
-
-
Chakravarti, A.1
Zhai, G.G.2
-
27
-
-
30944461586
-
PTEN and GSK3β: Key regulators of progression to androgen-independent prostate cancer
-
10.1038/sj.onc.1209020
-
DJ Mulholland S Dedhar H Wu 2006 PTEN and GSK3β: key regulators of progression to androgen-independent prostate cancer Oncogene 25 329 337 10.1038/sj.onc.1209020
-
(2006)
Oncogene
, vol.25
, pp. 329-337
-
-
Mulholland, D.J.1
Dedhar, S.2
Wu, H.3
-
28
-
-
0035043490
-
The carcinoembryonic antigen and its prognostic impact on immunocytologically detected intraperitoneal colorectal cancer cells
-
10.1016/S0002-9610(00)00555-9
-
I Vogel H Francksen E Soeth 2001 The carcinoembryonic antigen and its prognostic impact on immunocytologically detected intraperitoneal colorectal cancer cells Am J Surg 181 188 193 10.1016/S0002-9610(00)00555-9
-
(2001)
Am J Surg
, vol.181
, pp. 188-193
-
-
Vogel, I.1
Francksen, H.2
Soeth, E.3
-
29
-
-
33645950778
-
Histone deacetylase inhibitors: Multifunctional anticancer agents
-
10.1016/j.ctrv.2005.12.006
-
T Liu S Kuljaca A Tee 2006 Histone deacetylase inhibitors: multifunctional anticancer agents Cancer Treat Rev 32 157 165 10.1016/j.ctrv.2005.12.006
-
(2006)
Cancer Treat Rev
, vol.32
, pp. 157-165
-
-
Liu, T.1
Kuljaca, S.2
Tee, A.3
-
30
-
-
33644552484
-
Pathological evaluation of angiogenesis in human tumor
-
10.1016/S0753-3322(05)80068-X
-
H Sasano T Suzuki 2005 Pathological evaluation of angiogenesis in human tumor Biomed Pharmacother 59 S334 S336 10.1016/S0753-3322(05)80068-X
-
(2005)
Biomed Pharmacother
, vol.59
-
-
Sasano, H.1
Suzuki, T.2
-
31
-
-
17044416487
-
The involvement of endothelial progenitor cells in tumor angiogenesis
-
10.1111/j.1582-4934.2004.tb00319.x
-
D Ribatti 2004 The involvement of endothelial progenitor cells in tumor angiogenesis J Cell Mol Med 8 294 300 10.1111/j.1582-4934.2004.tb00319.x
-
(2004)
J Cell Mol Med
, vol.8
, pp. 294-300
-
-
Ribatti, D.1
-
32
-
-
18144364350
-
Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis
-
10.1016/j.cytogfr.2005.01.004
-
M Presta P Dell'Era S Mitola 2005 Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis Cytokine Growth Factor Rev 16 159 178 10.1016/j.cytogfr.2005.01.004
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, pp. 159-178
-
-
Presta, M.1
Dell'Era, P.2
Mitola, S.3
-
33
-
-
3242806189
-
Angiogenesis and prostate cancer tumor growth
-
10.1002/jcb.10772
-
B Nicholson D Theodorescu 2004 Angiogenesis and prostate cancer tumor growth J Cell Biochem 91 125 150 10.1002/jcb.10772
-
(2004)
J Cell Biochem
, vol.91
, pp. 125-150
-
-
Nicholson, B.1
Theodorescu, D.2
-
34
-
-
0035951364
-
Angiogenesis extent and expression of matrix metalloproteinase-2 and -9 correlate with progression in human neuroblastoma
-
10.1016/S0024-3205(00)01030-4
-
D Ribatti G Surico A Vacca 2001 Angiogenesis extent and expression of matrix metalloproteinase-2 and -9 correlate with progression in human neuroblastoma Life Sci 68 1161 1168 10.1016/S0024-3205(00)01030-4
-
(2001)
Life Sci
, vol.68
, pp. 1161-1168
-
-
Ribatti, D.1
Surico, G.2
Vacca, A.3
-
35
-
-
22144461042
-
Correlative studies on bFGF mRNA and MMP-9 mRNA expressions with microvascular density, progression, and prognosis of gastric carcinomas
-
ZS Zhao JL Zhou GY Yao 2005 Correlative studies on bFGF mRNA and MMP-9 mRNA expressions with microvascular density, progression, and prognosis of gastric carcinomas World J Gastroenterol 11 3227 3233
-
(2005)
World J Gastroenterol
, vol.11
, pp. 3227-3233
-
-
Zhao, Z.S.1
Zhou, J.L.2
Yao, G.Y.3
-
36
-
-
33344467274
-
KAI1/CD82 suppresses tumor invasion by MMP9 inactivation via TIMP1 up-regulation in the H1299 human lung carcinoma cell line
-
10.1016/j.bbrc.2006.01.153
-
BK Jee KM Park S Surendran 2006 KAI1/CD82 suppresses tumor invasion by MMP9 inactivation via TIMP1 up-regulation in the H1299 human lung carcinoma cell line Biochem Biophys Res Commun 342 655 661 10.1016/j.bbrc.2006.01.153
-
(2006)
Biochem Biophys Res Commun
, vol.342
, pp. 655-661
-
-
Jee, B.K.1
Park, K.M.2
Surendran, S.3
-
37
-
-
4143050461
-
New anticancer strategies targeting HIF-1
-
10.1016/j.bcp.2004.02.040
-
EJ Yeo YS Chun JW Park 2004 New anticancer strategies targeting HIF-1 Biochem Pharmacol 68 1061 1069 10.1016/j.bcp.2004.02.040
-
(2004)
Biochem Pharmacol
, vol.68
, pp. 1061-1069
-
-
Yeo, E.J.1
Chun, Y.S.2
Park, J.W.3
-
38
-
-
0033870727
-
Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth
-
15
-
HE Ryan M Poloni W McNulty 2000 Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth Cancer Res 60 15 4010 4015
-
(2000)
Cancer Res
, vol.60
, pp. 4010-4015
-
-
Ryan, H.E.1
Poloni, M.2
McNulty, W.3
-
39
-
-
0034667457
-
Ligand-independent activation of the androgen receptor by the differentiation agent butyrate in human prostate cancer cells
-
MD Sadar ME Gleave 2000 Ligand-independent activation of the androgen receptor by the differentiation agent butyrate in human prostate cancer cells Cancer Res 60 5825 5830
-
(2000)
Cancer Res
, vol.60
, pp. 5825-5830
-
-
Sadar, M.D.1
Gleave, M.E.2
-
40
-
-
0030462945
-
Pivalic acid-induced carnitine deficiency and physical exercise in humans
-
10.1016/S0026-0495(96)90179-1
-
K Abrahamsson BO Eriksson E Holme 1996 Pivalic acid-induced carnitine deficiency and physical exercise in humans Metabolism 45 1501 1507 10.1016/S0026-0495(96)90179-1
-
(1996)
Metabolism
, vol.45
, pp. 1501-1507
-
-
Abrahamsson, K.1
Eriksson, B.O.2
Holme, E.3
|