메뉴 건너뛰기




Volumn 15, Issue 1, 2018, Pages

Ageing: From inflammation to cancer

Author keywords

Ageing; Cancer; DAMPs; Inflammation; Microbiota; MiRna; Obesity; Senescence

Indexed keywords

MICRORNA;

EID: 85040795161     PISSN: None     EISSN: 17424933     Source Type: Journal    
DOI: 10.1186/s12979-017-0112-5     Document Type: Review
Times cited : (143)

References (92)
  • 2
    • 85040779482 scopus 로고    scopus 로고
    • Updates in pathobiology: causality and chance in ageing, age-related diseases and longevity
    • Accardi G, Caruso C, editors. Palermo: university press.
    • Accardi G, Caruso C. Updates in pathobiology: causality and chance in ageing, age-related diseases and longevity. In: Accardi G, Caruso C, editors. Updates in pathobiology: causality and chance in ageing, age-related diseases and longevity. Palermo: university press; 2017. p. 13-23.
    • (2017) Updates in pathobiology: causality and chance in ageing, age-related diseases and longevity , pp. 13-23
    • Accardi, G.1    Caruso, C.2
  • 4
    • 39649085837 scopus 로고    scopus 로고
    • Inflammaging as a major characteristic of old people: can it be prevented or cured?
    • Franceschi C. Inflammaging as a major characteristic of old people: can it be prevented or cured? Nutr Rev. 2007;65:173-6.
    • (2007) Nutr Rev , vol.65 , pp. 173-176
    • Franceschi, C.1
  • 5
    • 47949099098 scopus 로고    scopus 로고
    • Origin and physiological roles of inflammation
    • Medzhitov R. Origin and physiological roles of inflammation. Nature. 2008;454:428-35.
    • (2008) Nature , vol.454 , pp. 428-435
    • Medzhitov, R.1
  • 10
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-ΚB in cancer development and progression
    • Karin M. Nuclear factor-ΚB in cancer development and progression. Nature. 2006;441:431-6.
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 12
    • 40949123149 scopus 로고    scopus 로고
    • Activation of innate immunity system during ageing: NF-kB signaling is the molecular culprit of inflamm-ageing
    • Salminen A, Huuskonen J, Ojala J, Kauppinen A, Kaarniranta K, Suuronen T. Activation of innate immunity system during ageing: NF-kB signaling is the molecular culprit of inflamm-ageing. Ageing Res Rev. 2008;7:83-105.
    • (2008) Ageing Res Rev , vol.7 , pp. 83-105
    • Salminen, A.1    Huuskonen, J.2    Ojala, J.3    Kauppinen, A.4    Kaarniranta, K.5    Suuronen, T.6
  • 13
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: back to Virchow?
    • Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet. 2001;357:539-45.
    • (2001) Lancet , vol.357 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 15
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens LM, Werb Z. Inflammation and cancer. Nature. 2002;420:860-7.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 16
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144:646-74.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 18
    • 84867101876 scopus 로고    scopus 로고
    • Aspirin as adjuvant therapy for colorectal cancer-reinterpreting paradigms
    • Chia WK, Ali R, Toh HC. Aspirin as adjuvant therapy for colorectal cancer-reinterpreting paradigms. Nat Rev Clin Oncol. 2012;9:561-70.
    • (2012) Nat Rev Clin Oncol , vol.9 , pp. 561-570
    • Chia, W.K.1    Ali, R.2    Toh, H.C.3
  • 19
    • 85030469625 scopus 로고    scopus 로고
    • Beta-glucans and cancer: the influence of inflammation and gut peptide
    • Baldassano S, Accardi G, Vasto S. Beta-glucans and cancer: the influence of inflammation and gut peptide. Eur J Med Chem. 2017; https://doi.org/10.1016/j.ejmech.2017.09.013.
    • (2017) Eur J Med Chem
    • Baldassano, S.1    Accardi, G.2    Vasto, S.3
  • 21
    • 84881499244 scopus 로고    scopus 로고
    • Sex, gender and immunosenescence: a key to understand the different lifespan between men and women?
    • Caruso C, Accardi G, Virruso C, Candore G. Sex, gender and immunosenescence: a key to understand the different lifespan between men and women? Immun Ageing. 2013;10(Suppl 1):20.
    • (2013) Immun Ageing , vol.10 , pp. 20
    • Caruso, C.1    Accardi, G.2    Virruso, C.3    Candore, G.4
  • 22
    • 84904702784 scopus 로고    scopus 로고
    • Cellular senescence: from physiology to pathology
    • Muñoz-Espín D, Serrano M. Cellular senescence: from physiology to pathology. Nat Rev Mol Cell Biol. 2014;15:482-96.
    • (2014) Nat Rev Mol Cell Biol , vol.15 , pp. 482-496
    • Muñoz-Espín, D.1    Serrano, M.2
  • 23
    • 34548186667 scopus 로고    scopus 로고
    • Cellular senescence: when bad things happen to good cells
    • Campisi J, d'Adda di Fagagna F. Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol. 2007;8:729-40.
    • (2007) Nat Rev Mol Cell Biol. , vol.8 , pp. 729-740
    • Campisi, J.1    d'Adda di Fagagna, F.2
  • 24
    • 0035834121 scopus 로고    scopus 로고
    • Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging
    • Krtolica A, Parrinello S, Lockett S, Desprez PY, Campisi J. Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging. Proc Natl Acad Sci U S A. 2001;98:12072-7.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 12072-12077
    • Krtolica, A.1    Parrinello, S.2    Lockett, S.3    Desprez, P.Y.4    Campisi, J.5
  • 26
    • 58849154235 scopus 로고    scopus 로고
    • Senescence-messaging secretome: SMS-ing cellular stress
    • Kuilman T, Peeper DS. Senescence-messaging secretome: SMS-ing cellular stress. Nat Rev Cancer. 2009;9:81-94.
    • (2009) Nat Rev Cancer , vol.9 , pp. 81-94
    • Kuilman, T.1    Peeper, D.S.2
  • 29
    • 2442511752 scopus 로고    scopus 로고
    • Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)
    • Herbig U, Jobling WA, Chen BP, Chen DJ, Sedivy J. Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). Mol Cell. 2004;14:501-13.
    • (2004) Mol Cell , vol.14 , pp. 501-513
    • Herbig, U.1    Jobling, W.A.2    Chen, B.P.3    Chen, D.J.4    Sedivy, J.5
  • 30
    • 0027970713 scopus 로고
    • Damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts
    • DiLeonardo A, Linke SP, Clarkin K, Wahl GMDNA. Damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts. Genes Dev. 1994;8:2540-51.
    • (1994) Genes Dev , vol.8 , pp. 2540-2551
    • DiLeonardo, A.1    Linke, S.P.2    Clarkin, K.3    Wahl, G.M.D.N.A.4
  • 32
    • 0032190629 scopus 로고    scopus 로고
    • Premature senescence involving p53 and p16 is activated in response to constitutive MEK/ MAPK mitogenic signaling
    • Lin AW, Barradas M, Stone JC, van Aelst L, Serrano M, Lowe SW. Premature senescence involving p53 and p16 is activated in response to constitutive MEK/ MAPK mitogenic signaling. Genes Dev. 1998;12:3008-19.
    • (1998) Genes Dev , vol.12 , pp. 3008-3019
    • Lin, A.W.1    Barradas, M.2    Stone, J.C.3    van Aelst, L.4    Serrano, M.5    Lowe, S.W.6
  • 33
    • 11144268164 scopus 로고    scopus 로고
    • Significant role for p16(INK4a) in p53-independent telomere-directed senescence
    • Jacobs JJ, de Lange T. Significant role for p16(INK4a) in p53-independent telomere-directed senescence. Curr Biol. 2004;14:2302-8.
    • (2004) Curr Biol , vol.14 , pp. 2302-2308
    • Jacobs, J.J.1    de Lange, T.2
  • 36
    • 84856209016 scopus 로고    scopus 로고
    • Emerging role of NF-kappaB signaling in the induction of senescence-associated secretory phenotype (SASP)
    • Salminen A, Kauppinen A, Kaarniranta K. Emerging role of NF-kappaB signaling in the induction of senescence-associated secretory phenotype (SASP). Cell Signal. 2012;24:835-45.
    • (2012) Cell Signal , vol.24 , pp. 835-845
    • Salminen, A.1    Kauppinen, A.2    Kaarniranta, K.3
  • 37
    • 77949881221 scopus 로고    scopus 로고
    • The senescence-associated secretory phenotype: the dark side of tumor suppression
    • Coppe JP, Desprez PY, Krtolica A, Campisi J. The senescence-associated secretory phenotype: the dark side of tumor suppression. Annu Rev Pathol. 2010;5:99-118.
    • (2010) Annu Rev Pathol , vol.5 , pp. 99-118
    • Coppe, J.P.1    Desprez, P.Y.2    Krtolica, A.3    Campisi, J.4
  • 40
    • 13944270339 scopus 로고    scopus 로고
    • Senescent cells, tumor suppression and organismal aging: good citizens, bad neighbors
    • Campisi J. Senescent cells, tumor suppression and organismal aging: good citizens, bad neighbors. Cell. 2005;120:513-22.
    • (2005) Cell , vol.120 , pp. 513-522
    • Campisi, J.1
  • 41
    • 84874793452 scopus 로고    scopus 로고
    • IL1- and TGFbeta-Nox4 signaling, oxidative stress and DNA damage response are shared features of replicative, oncogene-induced, and drug-induced paracrine 'bystander senescence'
    • Hubackova S, Krejcikova K, Bartek J, Hodny Z. IL1- and TGFbeta-Nox4 signaling, oxidative stress and DNA damage response are shared features of replicative, oncogene-induced, and drug-induced paracrine 'bystander senescence'. Aging. 2012;4:932-51.
    • (2012) Aging , vol.4 , pp. 932-951
    • Hubackova, S.1    Krejcikova, K.2    Bartek, J.3    Hodny, Z.4
  • 43
    • 31544479046 scopus 로고    scopus 로고
    • The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms
    • Bavik C, Coleman I, Dean JP, Knudsen B, Plymate S, Nelson PS. The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms. Cancer Res. 2006;66:794-802.
    • (2006) Cancer Res , vol.66 , pp. 794-802
    • Bavik, C.1    Coleman, I.2    Dean, J.P.3    Knudsen, B.4    Plymate, S.5    Nelson, P.S.6
  • 44
    • 33749549246 scopus 로고    scopus 로고
    • Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence
    • Coppe JP, Kauser K, Campisi J, Beausejour CM. Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence. J Biol Chem. 2006;281:29568-74.
    • (2006) J Biol Chem , vol.281 , pp. 29568-29574
    • Coppe, J.P.1    Kauser, K.2    Campisi, J.3    Beausejour, C.M.4
  • 46
    • 84930836001 scopus 로고    scopus 로고
    • As mediators of sterile inflammation in aging- related pathologies
    • Feldman N, Rotter-Maskowitz A, Okun EDAMP. As mediators of sterile inflammation in aging- related pathologies. Ageing Res Rev. 2015;24:29-39.
    • (2015) Ageing Res Rev , vol.24 , pp. 29-39
    • Feldman, N.1    Rotter-Maskowitz, A.2    Okun, E.D.A.M.P.3
  • 47
    • 84900988267 scopus 로고    scopus 로고
    • Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases
    • Franceschi C, Campisi J. Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. J Gerontol A Biol Sci Med Sci. 2014;69(Suppl 1):4-9.
    • (2014) J Gerontol A Biol Sci Med Sci , vol.69 , pp. 4-9
    • Franceschi, C.1    Campisi, J.2
  • 48
    • 33745594044 scopus 로고    scopus 로고
    • The gut flora as a forgotten organ
    • O'Hara AM, Shanahan F. The gut flora as a forgotten organ. EMBO Rep. 2006;7:688-93.
    • (2006) EMBO Rep , vol.7 , pp. 688-693
    • O'Hara, A.M.1    Shanahan, F.2
  • 50
    • 7944231342 scopus 로고    scopus 로고
    • Does the microbiota regulate immune responses outside the gut?
    • Noverr MC, Huffnagle GB. Does the microbiota regulate immune responses outside the gut? Trends Microbiol. 2004;12:562-8.
    • (2004) Trends Microbiol , vol.12 , pp. 562-568
    • Noverr, M.C.1    Huffnagle, G.B.2
  • 51
    • 84948992933 scopus 로고    scopus 로고
    • Gut microbiota and aging
    • O'Toole PW, Jeffery IB. Gut microbiota and aging. Science. 2015;350:1214-5.
    • (2015) Science , vol.350 , pp. 1214-1215
    • O'Toole, P.W.1    Jeffery, I.B.2
  • 54
    • 0029935217 scopus 로고    scopus 로고
    • Age related changes in gut physiology and nutritional status
    • Lovat LB. Age related changes in gut physiology and nutritional status. Gut. 1996;38:306-9.
    • (1996) Gut , vol.38 , pp. 306-309
    • Lovat, L.B.1
  • 58
    • 69949187615 scopus 로고    scopus 로고
    • Connecting obesity, aging and diabetes
    • Ahima RS. Connecting obesity, aging and diabetes. Nat Med. 2009;15:996-7.
    • (2009) Nat Med , vol.15 , pp. 996-997
    • Ahima, R.S.1
  • 59
    • 81855225795 scopus 로고    scopus 로고
    • Molecular mechanisms of cancer development in obesity
    • Khandekar MJ, Cohen P, Spiegelman BM. Molecular mechanisms of cancer development in obesity. Nat Rev Cancer. 2011;11:886-95.
    • (2011) Nat Rev Cancer , vol.11 , pp. 886-895
    • Khandekar, M.J.1    Cohen, P.2    Spiegelman, B.M.3
  • 60
    • 38949108241 scopus 로고    scopus 로고
    • Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies
    • Renehan AG, Tyson M, Egger M, Heller RF, Zwahlen M. Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet. 2008;371:569-78.
    • (2008) Lancet , vol.371 , pp. 569-578
    • Renehan, A.G.1    Tyson, M.2    Egger, M.3    Heller, R.F.4    Zwahlen, M.5
  • 61
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil GS. Inflammation and metabolic disorders. Nature. 2006;444:860-7.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 63
    • 84903711756 scopus 로고    scopus 로고
    • Designing and developing a literature-derived, population-based dietary inflammatory index
    • Shivappa N, Steck SE, Hurley TG, Hussey JR, Hébert JR. Designing and developing a literature-derived, population-based dietary inflammatory index. Public Health Nutr. 2014;17:1689-96.
    • (2014) Public Health Nutr , vol.17 , pp. 1689-1696
    • Shivappa, N.1    Steck, S.E.2    Hurley, T.G.3    Hussey, J.R.4    Hébert, J.R.5
  • 64
  • 65
    • 3242771320 scopus 로고    scopus 로고
    • Adherence to the Mediterranean diet attenuates inflammation and coagulation process in healthy adults: the ATTICA study
    • Chrysohoou C, Panagiotakos DB, Pitsavos C, Das UN, Stefanadis C. Adherence to the Mediterranean diet attenuates inflammation and coagulation process in healthy adults: the ATTICA study. J Am Coll Cardiol. 2004;44:152-8.
    • (2004) J Am Coll Cardiol , vol.44 , pp. 152-158
    • Chrysohoou, C.1    Panagiotakos, D.B.2    Pitsavos, C.3    Das, U.N.4    Stefanadis, C.5
  • 66
    • 4544288392 scopus 로고    scopus 로고
    • Effect of a Mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: a randomized trial
    • Esposito K, Marfella R, Ciotola M, Di Palo C, Giugliano F, Giugliano G, D'Armiento M, D'Andrea F, Giugliano D. Effect of a Mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: a randomized trial. JAMA. 2004;292:1440-6.
    • (2004) JAMA , vol.292 , pp. 1440-1446
    • Esposito, K.1    Marfella, R.2    Ciotola, M.3    Di Palo, C.4    Giugliano, F.5    Giugliano, G.6    D'Armiento, M.7    D'Andrea, F.8    Giugliano, D.9
  • 75
    • 85013912369 scopus 로고    scopus 로고
    • Prospective study of the dietary in ammatory index and risk of breast cancer in postmenopausal women
    • Shivappa N, Blair CK, Prizment AE, Jacobs DR, Hebert JR. Prospective study of the dietary in ammatory index and risk of breast cancer in postmenopausal women. Mol Nutr Food Res. 2016;61:5.
    • (2016) Mol Nutr Food Res , vol.61 , pp. 5
    • Shivappa, N.1    Blair, C.K.2    Prizment, A.E.3    Jacobs, D.R.4    Hebert, J.R.5
  • 78
    • 84859937089 scopus 로고    scopus 로고
    • Extending healthy ageing: nutrient sensitive pathway and centenarian population
    • Davinelli S, Willcox DC, Scapagnini G. Extending healthy ageing: nutrient sensitive pathway and centenarian population. Immun Ageing. 2012;9:9.
    • (2012) Immun Ageing , vol.9 , pp. 9
    • Davinelli, S.1    Willcox, D.C.2    Scapagnini, G.3
  • 80
    • 84973872520 scopus 로고    scopus 로고
    • Dietary phytochemicals and neuro-inflammaging: from mechanistic insights to translational challenges
    • Davinelli S, Maes M, Corbi G, Zarrelli A, Willcox DC, Scapagnini G. Dietary phytochemicals and neuro-inflammaging: from mechanistic insights to translational challenges. Immun Ageing. 2016;13:16.
    • (2016) Immun Ageing , vol.13 , pp. 16
    • Davinelli, S.1    Maes, M.2    Corbi, G.3    Zarrelli, A.4    Willcox, D.C.5    Scapagnini, G.6
  • 83
    • 84880036063 scopus 로고    scopus 로고
    • miRTar hunter: a prediction system for identifying human microRNA target sites
    • Park K, Kim KB. miRTar hunter: a prediction system for identifying human microRNA target sites. Molecules and Cells. 2013;35:195-201.
    • (2013) Molecules and Cells , vol.35 , pp. 195-201
    • Park, K.1    Kim, K.B.2
  • 84
    • 77954385729 scopus 로고    scopus 로고
    • The complexities of microRNA regulation: mirandering around the rules
    • Breving K, Esquela-Kerscher A. The complexities of microRNA regulation: mirandering around the rules. Int J Biochem Cell Biol. 2010;42:1316-29.
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 1316-1329
    • Breving, K.1    Esquela-Kerscher, A.2
  • 85
    • 84857981122 scopus 로고    scopus 로고
    • Small but smart-- microRNAs in the centre of inflammatory processes during cardiovascular diseases, the metabolic syndrome, and ageing
    • Schroen B, Heymans S. Small but smart-- microRNAs in the centre of inflammatory processes during cardiovascular diseases, the metabolic syndrome, and ageing. Cardiovasc Res. 2012;93:605-13.
    • (2012) Cardiovasc Res , vol.93 , pp. 605-613
    • Schroen, B.1    Heymans, S.2
  • 87
    • 84859748673 scopus 로고    scopus 로고
    • Towards the understanding of microRNA and environmental factor interactions and their relationships to human diseases
    • Qiu C, Chen G, Cui Q. Towards the understanding of microRNA and environmental factor interactions and their relationships to human diseases. Sci Rep. 2012;2:318.
    • (2012) Sci Rep , vol.2 , pp. 318
    • Qiu, C.1    Chen, G.2    Cui, Q.3
  • 88
    • 84929466417 scopus 로고    scopus 로고
    • MicroRNAs as potential signatures of environmental exposure or effect: a systematic review
    • Vrijens K, Bollati V, Nawrot TS. MicroRNAs as potential signatures of environmental exposure or effect: a systematic review. Environ Health Perspect. 2015;123(Suppl 5):399-411.
    • (2015) Environ Health Perspect , vol.123 , pp. 399-411
    • Vrijens, K.1    Bollati, V.2    Nawrot, T.S.3
  • 92
    • 84940791902 scopus 로고    scopus 로고
    • microRNA-based diagnostics and therapy in cardiovascular disease-summing up the facts
    • Schulte C, Zeller T. microRNA-based diagnostics and therapy in cardiovascular disease-summing up the facts. Cardiovasc Diagn Ther. 2015;5(Suppl 1):17-36.
    • (2015) Cardiovasc Diagn Ther , vol.5 , pp. 17-36
    • Schulte, C.1    Zeller, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.