메뉴 건너뛰기




Volumn 10, Issue 1, 2018, Pages

TGF-β family signaling in epithelial differentiation and epithelial-mesenchymal transition

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

EID: 85040123393     PISSN: None     EISSN: 19430264     Source Type: Journal    
DOI: 10.1101/cshperspect.a022194     Document Type: Article
Times cited : (96)

References (236)
  • 1
    • 67650996280 scopus 로고    scopus 로고
    • Epithelial -mesenchymal transitions: The importance of changing cell state in development and disease
    • Acloque H, Adams MS, Fishwick K, Bronner-Fraser M, Nieto MA. 2009. Epithelial -mesenchymal transitions: The importance of changing cell state in development and disease. J Clin Invest 119: 1438-1449.
    • (2009) J Clin Invest , vol.119 , pp. 1438-1449
    • Acloque, H.1    Adams, M.S.2    Fishwick, K.3    Bronner-Fraser, M.4    Nieto, M.A.5
  • 2
    • 34548444180 scopus 로고    scopus 로고
    • Mechanisms of palatal epithelial seam disintegration by transforming growth factor (TGF) b3
    • Ahmed S, Liu CC, Nawshad A. 2007. Mechanisms of palatal epithelial seam disintegration by transforming growth factor (TGF) b3. Dev Biol 309: 193-207.
    • (2007) Dev Biol , vol.309 , pp. 193-207
    • Ahmed, S.1    Liu, C.C.2    Nawshad, A.3
  • 3
    • 0032500010 scopus 로고    scopus 로고
    • Expression of a dominant negative type II TGF-β receptor in mouse skin results in an increase in carcinoma incidence and an acceleration of carcinoma development
    • Amendt C, Schirmacher P, Weber H, Blessing M. 1998. Expression of a dominant negative type II TGF-β receptor in mouse skin results in an increase in carcinoma incidence and an acceleration of carcinoma development. Oncogene 17: 25-34.
    • (1998) Oncogene , vol.17 , pp. 25-34
    • Amendt, C.1    Schirmacher, P.2    Weber, H.3    Blessing, M.4
  • 4
    • 35748943880 scopus 로고    scopus 로고
    • Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development
    • Andersson O, Bertolino P, Ibanez CF. 2007. Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development. Dev Biol 311: 500-511.
    • (2007) Dev Biol , vol.311 , pp. 500-511
    • Andersson, O.1    Bertolino, P.2    Ibanez, C.F.3
  • 5
    • 0036113510 scopus 로고    scopus 로고
    • WNT signals are required for the initiation of hair follicle development
    • Andl T, Reddy ST, Gaddapara T, Millar SE. 2002. WNT signals are required for the initiation of hair follicle development. Dev Cell 2: 643-653.
    • (2002) Dev Cell , vol.2 , pp. 643-653
    • Andl, T.1    Reddy, S.T.2    Gaddapara, T.3    Millar, S.E.4
  • 7
    • 41649084206 scopus 로고    scopus 로고
    • Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse
    • Arnold SJ, Hofmann UK, Bikoff EK, Robertson EJ. 2008. Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse. Development 135: 501-511.
    • (2008) Development , vol.135 , pp. 501-511
    • Arnold, S.J.1    Hofmann, U.K.2    Bikoff, E.K.3    Robertson, E.J.4
  • 8
    • 0036218011 scopus 로고    scopus 로고
    • Signalling via type IA and type IB bone morphogenetic protein receptors (BMPR) regulates intramembranous bone formation, chondrogenesis and feather formation in the chicken embryo
    • Ashique AM, Fu K, Richman JM. 2002. Signalling via type IA and type IB bone morphogenetic protein receptors (BMPR) regulates intramembranous bone formation, chondrogenesis and feather formation in the chicken embryo. Int J Dev Biol 46: 243-253.
    • (2002) Int J Dev Biol , vol.46 , pp. 243-253
    • Ashique, A.M.1    Fu, K.2    Richman, J.M.3
  • 9
    • 24044509109 scopus 로고    scopus 로고
    • Activin controls skin morphogenesis and wound repair predominantly via stromal cells and in a concentration-dependent manner via keratinocytes
    • Bamberger C, Scharer A, Antsiferova M, Tychsen B, Pankow S, Muller M, Rulicke T, Paus R, Werner S. 2005. Activin controls skin morphogenesis and wound repair predominantly via stromal cells and in a concentration-dependent manner via keratinocytes. Am J Pathol 167: 733- 747.
    • (2005) Am J Pathol , vol.167 , pp. 733-747
    • Bamberger, C.1    Scharer, A.2    Antsiferova, M.3    Tychsen, B.4    Pankow, S.5    Muller, M.6    Rulicke, T.7    Paus, R.8    Werner, S.9
  • 10
    • 3042677490 scopus 로고    scopus 로고
    • Drm/Gremlin, a BMP antagonist, defines the interbud region during feather development
    • Bardot B, Lecoin L, Fliniaux I, Huillard E, Marx M, Viallet JP. 2004. Drm/Gremlin, a BMP antagonist, defines the interbud region during feather development. Int J Dev Biol 48: 149-156.
    • (2004) Int J Dev Biol , vol.48 , pp. 149-156
    • Bardot, B.1    Lecoin, L.2    Fliniaux, I.3    Huillard, E.4    Marx, M.5    Viallet, J.P.6
  • 12
    • 0036672240 scopus 로고    scopus 로고
    • Bone morphogenetic protein signaling and the initiation of lens fiber cell differentiation
    • Belecky-Adams TL, Adler R, Beebe DC. 2002. Bone morphogenetic protein signaling and the initiation of lens fiber cell differentiation. Development 129: 3795-3802.
    • (2002) Development , vol.129 , pp. 3795-3802
    • Belecky-Adams, T.L.1    Adler, R.2    Beebe, D.C.3
  • 13
    • 4243084522 scopus 로고    scopus 로고
    • Determination of embryonic polarity in a regulative system: Evidence for endogenous inhibitors acting sequentially during primitive streak formation in the chick embryo
    • Bertocchini F, Skromne I, Wolpert L, Stern CD. 2004. Determination of embryonic polarity in a regulative system: Evidence for endogenous inhibitors acting sequentially during primitive streak formation in the chick embryo. Development 131: 3381-3390.
    • (2004) Development , vol.131 , pp. 3381-3390
    • Bertocchini, F.1    Skromne, I.2    Wolpert, L.3    Stern, C.D.4
  • 14
    • 84933544655 scopus 로고    scopus 로고
    • BMP gradients: A paradigm for morphogen-mediated developmental patterning
    • Bier E, De Robertis EM. 2015. BMP gradients: A paradigm for morphogen-mediated developmental patterning. Science 348: aaa5838.
    • (2015) Science , vol.348
    • Bier, E.1    De Robertis, E.M.2
  • 15
    • 0028837742 scopus 로고
    • Hedgehog and Bmp genes are coexpressed at many diverse sites of cell -cell interaction in the mouse embryo
    • Bitgood MJ, McMahon AP. 1995. Hedgehog and Bmp genes are coexpressed at many diverse sites of cell -cell interaction in the mouse embryo. Dev Biol 172: 126-138.
    • (1995) Dev Biol , vol.172 , pp. 126-138
    • Bitgood, M.J.1    McMahon, A.P.2
  • 16
  • 17
    • 84902603107 scopus 로고    scopus 로고
    • Plasticity of epithelial stem cells in tissue regeneration
    • Blanpain C, Fuchs E. 2014. Plasticity of epithelial stem cells in tissue regeneration. Science 344: 1242281.
    • (2014) Science , vol.344
    • Blanpain, C.1    Fuchs, E.2
  • 18
    • 4444290010 scopus 로고    scopus 로고
    • Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche
    • Blanpain C, Lowry WE, Geoghegan A, Polak L, Fuchs E. 2004. Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell 118: 635-648.
    • (2004) Cell , vol.118 , pp. 635-648
    • Blanpain, C.1    Lowry, W.E.2    Geoghegan, A.3    Polak, L.4    Fuchs, E.5
  • 19
    • 0027478822 scopus 로고
    • Transgenic mice as a model to study the role of TGF-β-related molecules in hair follicles
    • Blessing M, Nanney LB, King LE, Jones CM, Hogan BL. 1993. Transgenic mice as a model to study the role of TGF-β-related molecules in hair follicles. Genes Dev 7: 204-215.
    • (1993) Genes Dev , vol.7 , pp. 204-215
    • Blessing, M.1    Nanney, L.B.2    King, L.E.3    Jones, C.M.4    Hogan, B.L.5
  • 20
    • 0029834634 scopus 로고    scopus 로고
    • Overexpression of bone morphogenetic protein-6 (BMP-6) in the epidermis of transgenic mice: Inhibition or stimulation of proliferation depending on the pattern of transgene expression and formation of psoriatic lesions
    • Blessing M, Schirmacher P, Kaiser S. 1996. Overexpression of bone morphogenetic protein-6 (BMP-6) in the epidermis of transgenic mice: Inhibition or stimulation of proliferation depending on the pattern of transgene expression and formation of psoriatic lesions. J Cell Biol 135: 227-239.
    • (1996) J Cell Biol , vol.135 , pp. 227-239
    • Blessing, M.1    Schirmacher, P.2    Kaiser, S.3
  • 21
    • 84934299864 scopus 로고    scopus 로고
    • Synergistic interaction between the fibroblast growth factor and bone morphogenetic protein signaling pathways in lens cells
    • Boswell BA, Musil LS. 2015. Synergistic interaction between the fibroblast growth factor and bone morphogenetic protein signaling pathways in lens cells. Mol Biol Cell 26: 2561-2572.
    • (2015) Mol Biol Cell , vol.26 , pp. 2561-2572
    • Boswell, B.A.1    Musil, L.S.2
  • 24
    • 0036151314 scopus 로고    scopus 로고
    • Modulation of BMP signaling by noggin is required for induction of the secondary (Non-tylotrich) hair follicles
    • Botchkarev VA, Botchkareva NV, Sharov AA, Funa K, Huber O, Gilchrest BA. 2002. Modulation of BMP signaling by noggin is required for induction of the secondary (non-tylotrich) hair follicles. J Invest Dermatol 118: 3-10.
    • (2002) J Invest Dermatol , vol.118 , pp. 3-10
    • Botchkarev, V.A.1    Botchkareva, N.V.2    Sharov, A.A.3    Funa, K.4    Huber, O.5    Gilchrest, B.A.6
  • 25
    • 84867399464 scopus 로고    scopus 로고
    • Formation and migration of neural crest cells in the vertebrate embryo
    • Bronner ME. 2012. Formation and migration of neural crest cells in the vertebrate embryo. Histochem Cell Biol 138: 179-186.
    • (2012) Histochem Cell Biol , vol.138 , pp. 179-186
    • Bronner, M.E.1
  • 26
    • 0023752757 scopus 로고
    • Cell lineage analysis reveals multipotency of some avian neural crest cells
    • Bronner-Fraser M, Fraser SE. 1988. Cell lineage analysis reveals multipotency of some avian neural crest cells. Nature 335: 161-164.
    • (1988) Nature , vol.335 , pp. 161-164
    • Bronner-Fraser, M.1    Fraser, S.E.2
  • 27
    • 9444225533 scopus 로고    scopus 로고
    • Canonical Wnt activity regulates trunk neural crest delamination linking BMP/noggin signaling with G1/S transition
    • Burstyn-Cohen T, Stanleigh J, Sela-Donenfeld D, Kalcheim C. 2004. Canonical Wnt activity regulates trunk neural crest delamination linking BMP/noggin signaling with G1/S transition. Development 131: 5327-5339.
    • (2004) Development , vol.131 , pp. 5327-5339
    • Burstyn-Cohen, T.1    Stanleigh, J.2    Sela-Donenfeld, D.3    Kalcheim, C.4
  • 28
    • 83755225339 scopus 로고    scopus 로고
    • Palatogenesis: Morphogenetic and molecular mechanisms of secondary palate development
    • Bush JO, Jiang R. 2012. Palatogenesis: Morphogenetic and molecular mechanisms of secondary palate development. Development 139: 231-243.
    • (2012) Development , vol.139 , pp. 231-243
    • Bush, J.O.1    Jiang, R.2
  • 29
    • 79958845021 scopus 로고    scopus 로고
    • Msx2 and Foxn1 regulate nail homeostasis
    • Cai J, Ma L. 2011. Msx2 and Foxn1 regulate nail homeostasis. Genesis 49: 449-459.
    • (2011) Genesis , vol.49 , pp. 449-459
    • Cai, J.1    Ma, L.2
  • 30
    • 0035479815 scopus 로고    scopus 로고
    • Monstrous attempts at adnexo-genesis: Regulating hair follicle progenitors through Sonic Hedgehog signaling
    • Callahan CA, Oro AE. 2001. Monstrous attempts at adnexo-genesis: Regulating hair follicle progenitors through Sonic Hedgehog signaling. Curr Opin Genet Dev 11: 541-546.
    • (2001) Curr Opin Genet Dev , vol.11 , pp. 541-546
    • Callahan, C.A.1    Oro, A.E.2
  • 34
    • 25444497451 scopus 로고    scopus 로고
    • Nodal signaling and the evolution of deuterostome gastrulation
    • Chea HK, Wright CV, Swalla BJ. 2005. Nodal signaling and the evolution of deuterostome gastrulation. Dev Dyn 234: 269-278.
    • (2005) Dev Dyn , vol.234 , pp. 269-278
    • Chea, H.K.1    Wright, C.V.2    Swalla, B.J.3
  • 35
    • 84899504418 scopus 로고    scopus 로고
    • ERK1/2 pathway mediates epithelial-mesenchymal transition by cross-interacting with TGFβ/Smad and Jagged/Notch signaling pathways in lens epithelial cells
    • Chen X, Ye S, Xiao W, Wang W, Luo L, Liu Y. 2014. ERK1/2 pathway mediates epithelial-mesenchymal transition by cross-interacting with TGFβ/Smad and Jagged/Notch signaling pathways in lens epithelial cells. Int J Mol Med 33: 1664-1670.
    • (2014) Int J Mol Med , vol.33 , pp. 1664-1670
    • Chen, X.1    Ye, S.2    Xiao, W.3    Wang, W.4    Luo, L.5    Liu, Y.6
  • 36
    • 13344259902 scopus 로고    scopus 로고
    • The transcriptional control of trunk neural crest induction, survival, and delamination
    • Cheung M, Chaboissier MC, Mynett A, Hirst E, Schedl A, Briscoe J. 2005. The transcriptional control of trunk neural crest induction, survival, and delamination. Dev Cell 8: 179-192.
    • (2005) Dev Cell , vol.8 , pp. 179-192
    • Cheung, M.1    Chaboissier, M.C.2    Mynett, A.3    Hirst, E.4    Schedl, A.5    Briscoe, J.6
  • 38
    • 33845787629 scopus 로고    scopus 로고
    • Snail is required for transforming growth factor-b-induced epithelial-mesenchymal transition by activating PI3 kinase/Akt signal pathway
    • Cho HJ, Baek KE, Saika S, Jeong MJ, Yoo J. 2007. Snail is required for transforming growth factor-b-induced epithelial-mesenchymal transition by activating PI3 kinase/Akt signal pathway. Biochem Biophys Res Commun 353: 337-343.
    • (2007) Biochem Biophys Res Commun , vol.353 , pp. 337-343
    • Cho, H.J.1    Baek, K.E.2    Saika, S.3    Jeong, M.J.4    Yoo, J.5
  • 39
    • 34347255755 scopus 로고    scopus 로고
    • Transforming growth factor-b1 represses E-cadherin production via slug expression in lens epithelial cells
    • Choi J, Park SY, Joo CK. 2007. Transforming growth factor-b1 represses E-cadherin production via slug expression in lens epithelial cells. Invest Ophthalmol Vis Sci 48: 2708- 2718.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 2708-2718
    • Choi, J.1    Park, S.Y.2    Joo, C.K.3
  • 41
  • 42
    • 84902214874 scopus 로고    scopus 로고
    • Cadherin 6 promotes neural crest cell detachment via F-actin regulation and influences active Rho distribution during epithelial-to-mesenchymal transition
    • Clay MR, Halloran MC. 2014. Cadherin 6 promotes neural crest cell detachment via F-actin regulation and influences active Rho distribution during epithelial-to-mesenchymal transition. Development 141: 2506-2515.
    • (2014) Development , vol.141 , pp. 2506-2515
    • Clay, M.R.1    Halloran, M.C.2
  • 43
    • 0028986244 scopus 로고
    • Concerted action of TGF-β1 and its type II receptor in control of epidermal homeostasis in transgenic mice
    • Cui W, Fowlis DJ, Cousins FM, Duffie E, Bryson S, Balmain A, Akhurst RJ. 1995. Concerted action of TGF-β1 and its type II receptor in control of epidermal homeostasis in transgenic mice. Genes Dev 9: 945-955.
    • (1995) Genes Dev , vol.9 , pp. 945-955
    • Cui, W.1    Fowlis, D.J.2    Cousins, F.M.3    Duffie, E.4    Bryson, S.5    Balmain, A.6    Akhurst, R.J.7
  • 44
    • 0001238958 scopus 로고
    • The development of mouse vibrissae in vivo and in vitro
    • Davidson P, Hardy MH. 1952. The development of mouse vibrissae in vivo and in vitro. J Anat 86: 342-356.
    • (1952) J Anat , vol.86 , pp. 342-356
    • Davidson, P.1    Hardy, M.H.2
  • 47
    • 13944274193 scopus 로고    scopus 로고
    • Neural induction in Xenopus requires early FGF signalling in addition to BMP inhibition
    • Delaune E, Lemaire P, Kodjabachian L. 2005. Neural induction in Xenopus requires early FGF signalling in addition to BMP inhibition. Development 132: 299-310.
    • (2005) Development , vol.132 , pp. 299-310
    • Delaune, E.1    Lemaire, P.2    Kodjabachian, L.3
  • 48
    • 0036138749 scopus 로고    scopus 로고
    • Opposing effects on TSC-22 expression by BMP and receptor tyrosine kinase signals in the developing feather tract
    • Dohrmann CE, Noramly S, Raftery LA, Morgan BA. 2002. Opposing effects on TSC-22 expression by BMP and receptor tyrosine kinase signals in the developing feather tract. Dev Dyn 223: 85-95.
    • (2002) Dev Dyn , vol.223 , pp. 85-95
    • Dohrmann, C.E.1    Noramly, S.2    Raftery, L.A.3    Morgan, B.A.4
  • 49
    • 84884891955 scopus 로고    scopus 로고
    • EGFR-Ras-Raf signaling in epidermal stem cells: Roles in hair follicle development, regeneration, tissue remodeling and epidermal cancers
    • Doma E, Rupp C, Baccarini M. 2013. EGFR-Ras-Raf signaling in epidermal stem cells: Roles in hair follicle development, regeneration, tissue remodeling and epidermal cancers. Int J Mol Sci 14: 19361-19384.
    • (2013) Int J Mol Sci , vol.14 , pp. 19361-19384
    • Doma, E.1    Rupp, C.2    Baccarini, M.3
  • 50
    • 0035164747 scopus 로고    scopus 로고
    • The winged-helix transcription factor Foxd3 suppresses interneuron differentiation and promotes neural crest cell fate
    • Dottori M, Gross MK, Labosky P, Goulding M. 2001. The winged-helix transcription factor Foxd3 suppresses interneuron differentiation and promotes neural crest cell fate. Development 128: 4127-4138.
    • (2001) Development , vol.128 , pp. 4127-4138
    • Dottori, M.1    Gross, M.K.2    Labosky, P.3    Goulding, M.4
  • 51
    • 0347091742 scopus 로고    scopus 로고
    • TGF-β3-induced palatal fusion is mediated by Alk-5/Smad pathway
    • Dudas M, Nagy A, Laping NJ, Moustakas A, Kaartinen V. 2004. TGF-β3-induced palatal fusion is mediated by Alk-5/Smad pathway. Dev Biol 266: 96-108.
    • (2004) Dev Biol , vol.266 , pp. 96-108
    • Dudas, M.1    Nagy, A.2    Laping, N.J.3    Moustakas, A.4    Kaartinen, V.5
  • 52
    • 0032529168 scopus 로고    scopus 로고
    • Activin is an essential early mesenchymal signal in tooth development that is required for patterning of the murine dentition
    • Ferguson CA, Tucker AS, Christensen L, Lau AL, Matzuk MM, Sharpe PT. 1998. Activin is an essential early mesenchymal signal in tooth development that is required for patterning of the murine dentition. Genes Dev 12: 2636-2649.
    • (1998) Genes Dev , vol.12 , pp. 2636-2649
    • Ferguson, C.A.1    Tucker, A.S.2    Christensen, L.3    Lau, A.L.4    Matzuk, M.M.5    Sharpe, P.T.6
  • 53
    • 0036788628 scopus 로고    scopus 로고
    • Disruption of anterior segment development by TGF-β1 overexpression in the eyes of transgenic mice
    • Flügel-Koch C, Ohlmann A, Piatigorsky J, Tamm ER. 2002. Disruption of anterior segment development by TGF-β1 overexpression in the eyes of transgenic mice. Dev Dyn 225: 111-125.
    • (2002) Dev Dyn , vol.225 , pp. 111-125
    • Flügel-Koch, C.1    Ohlmann, A.2    Piatigorsky, J.3    Tamm, E.R.4
  • 54
    • 0033566365 scopus 로고    scopus 로고
    • The TGFβ2 isoform is both a required and sufficient inducer of murine hair follicle morphogenesis
    • Foitzik K, Paus R, Doetschman T, Dotto GP. 1999. The TGFβ2 isoform is both a required and sufficient inducer of murine hair follicle morphogenesis. Dev Biol 212: 278- 289.
    • (1999) Dev Biol , vol.212 , pp. 278-289
    • Foitzik, K.1    Paus, R.2    Doetschman, T.3    Dotto, G.P.4
  • 56
    • 33847235717 scopus 로고    scopus 로고
    • Scratching the surface of skin development
    • Fuchs E. 2007. Scratching the surface of skin development. Nature 445: 834-842.
    • (2007) Nature , vol.445 , pp. 834-842
    • Fuchs, E.1
  • 57
    • 39749157093 scopus 로고    scopus 로고
    • Sustained TGFβ exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMTand inhibition of growth arrest and apoptosis
    • Gal A, Sjöblom T, Fedorova L, Imreh S, Beug H, Moustakas A. 2008. Sustained TGFβ exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMTand inhibition of growth arrest and apoptosis. Oncogene 27: 1218-1230.
    • (2008) Oncogene , vol.27 , pp. 1218-1230
    • Gal, A.1    Sjöblom, T.2    Fedorova, L.3    Imreh, S.4    Beug, H.5    Moustakas, A.6
  • 59
    • 70350526983 scopus 로고    scopus 로고
    • Disruption of Smad4 in odontoblasts causes multiple keratocystic odontogenic tumors and tooth malformation in mice
    • Gao Y, Yang G, Weng T, Du J, Wang X, Zhou J, Wang S, Yang X. 2009. Disruption of Smad4 in odontoblasts causes multiple keratocystic odontogenic tumors and tooth malformation in mice. Mol Cell Biol 29: 5941-5951.
    • (2009) Mol Cell Biol , vol.29 , pp. 5941-5951
    • Gao, Y.1    Yang, G.2    Weng, T.3    Du, J.4    Wang, X.5    Zhou, J.6    Wang, S.7    Yang, X.8
  • 61
    • 0032567078 scopus 로고    scopus 로고
    • De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated b-catenin in skin
    • Gat U, DasGupta R, Degenstein L, Fuchs E. 1998. De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated b-catenin in skin. Cell 95: 605-614.
    • (1998) Cell , vol.95 , pp. 605-614
    • Gat, U.1    Dasgupta, R.2    Degenstein, L.3    Fuchs, E.4
  • 63
    • 0031882022 scopus 로고    scopus 로고
    • Hoxc13 mutant mice lack external hair
    • Godwin AR, Capecchi MR. 1998. Hoxc13 mutant mice lack external hair. Genes Dev 12: 11-20.
    • (1998) Genes Dev , vol.12 , pp. 11-20
    • Godwin, A.R.1    Capecchi, M.R.2
  • 65
    • 39249084246 scopus 로고    scopus 로고
    • Development and regeneration of the neonatal digit tip in mice
    • Han M, Yang X, Lee J, Allan CH, Muneoka K. 2008. Development and regeneration of the neonatal digit tip in mice. Dev Biol 315: 125-135.
    • (2008) Dev Biol , vol.315 , pp. 125-135
    • Han, M.1    Yang, X.2    Lee, J.3    Allan, C.H.4    Muneoka, K.5
  • 66
    • 0026571418 scopus 로고
    • The secret life of the hair follicle
    • Hardy MH. 1992. The secret life of the hair follicle. Trends Genet 8: 55-61.
    • (1992) Trends Genet , vol.8 , pp. 55-61
    • Hardy, M.H.1
  • 67
    • 23844501009 scopus 로고    scopus 로고
    • Molecular evidence for an activator-inhibitor mechanism in development of embryonic feather branching
    • Harris MP, Williamson S, Fallon JF, Meinhardt H, Prum RO. 2005. Molecular evidence for an activator-inhibitor mechanism in development of embryonic feather branching. Proc Natl Acad Sci 102: 11734-11739.
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 11734-11739
    • Harris, M.P.1    Williamson, S.2    Fallon, J.F.3    Meinhardt, H.4    Prum, R.O.5
  • 69
    • 0029553183 scopus 로고
    • An overview of epithelio-mesenchymal transformation
    • Hay ED. 1995. An overview of epithelio-mesenchymal transformation. Acta Anat 154: 8-20.
    • (1995) Acta Anat , vol.154 , pp. 8-20
    • Hay, E.D.1
  • 70
    • 84930697193 scopus 로고    scopus 로고
    • Augmented BMP signaling in the neural crest inhibits nasal cartilage morphogenesis by inducing p53-mediated apoptosis
    • Hayano S, Komatsu Y, Pan H, Mishina Y. 2015. Augmented BMP signaling in the neural crest inhibits nasal cartilage morphogenesis by inducing p53-mediated apoptosis. Development 142: 1357-1367.
    • (2015) Development , vol.142 , pp. 1357-1367
    • Hayano, S.1    Komatsu, Y.2    Pan, H.3    Mishina, Y.4
  • 71
    • 0035945639 scopus 로고    scopus 로고
    • Smads mediate signaling of the TGFβ superfamily in normal keratinocytes but are lost during skin chemical carcinogenesis
    • He W, Cao T, Smith DA, Myers TE, Wang XJ. 2001. Smads mediate signaling of the TGFβ superfamily in normal keratinocytes but are lost during skin chemical carcinogenesis. Oncogene 20: 471-483.
    • (2001) Oncogene , vol.20 , pp. 471-483
    • He, W.1    Cao, T.2    Smith, D.A.3    Myers, T.E.4    Wang, X.J.5
  • 72
    • 0037013859 scopus 로고    scopus 로고
    • Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues
    • He W, Wang D, Han S, Zheng B, ten Dijke P. 2002. Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues. EMBO J 21: 2580-2590.
    • (2002) EMBO J , vol.21 , pp. 2580-2590
    • He, W.1    Wang, D.2    Han, S.3    Zheng, B.4    Ten Dijke, P.5
  • 73
    • 84964695720 scopus 로고    scopus 로고
    • Eye morphogenesis driven by epithelial flow into the optic cup facilitated by modulation of bone morphogenetic protein
    • Heermann S, Schutz L, Lemke S, Krieglstein K, Wittbrodt J. 2015. Eye morphogenesis driven by epithelial flow into the optic cup facilitated by modulation of bone morphogenetic protein. eLife 4: e05216.
    • (2015) Elife , vol.4
    • Heermann, S.1    Schutz, L.2    Lemke, S.3    Krieglstein, K.4    Wittbrodt, J.5
  • 74
    • 78650963929 scopus 로고    scopus 로고
    • Dynamics between stem cells, niche, and progeny in the hair follicle
    • Hsu YC, Pasolli HA, Fuchs E. 2011. Dynamics between stem cells, niche, and progeny in the hair follicle. Cell 144: 92- 105.
    • (2011) Cell , vol.144 , pp. 92-105
    • Hsu, Y.C.1    Pasolli, H.A.2    Fuchs, E.3
  • 75
    • 84900310460 scopus 로고    scopus 로고
    • Transit-amplifying cells orchestrate stem cell activity and tissue regeneration
    • Hsu YC, Li L, Fuchs E. 2014. Transit-amplifying cells orchestrate stem cell activity and tissue regeneration. Cell 157: 935-949.
    • (2014) Cell , vol.157 , pp. 935-949
    • Hsu, Y.C.1    Li, L.2    Fuchs, E.3
  • 76
    • 84872200824 scopus 로고    scopus 로고
    • Early events in cell adhesion and polarity during epithelial-mesenchymal transition
    • Huang RY, Guilford P, Thiery JP. 2012. Early events in cell adhesion and polarity during epithelial-mesenchymal transition. J Cell Sci 125: 4417-4422.
    • (2012) J Cell Sci , vol.125 , pp. 4417-4422
    • Huang, R.Y.1    Guilford, P.2    Thiery, J.P.3
  • 77
    • 84952861473 scopus 로고    scopus 로고
    • Negative and positive auto-regulation of BMP expression in early eye development
    • Huang J, Liu Y, Filas B, Gunhaga L, Beebe DC. 2015. Negative and positive auto-regulation of BMP expression in early eye development. Dev Biol 407: 256-264.
    • (2015) Dev Biol , vol.407 , pp. 256-264
    • Huang, J.1    Liu, Y.2    Filas, B.3    Gunhaga, L.4    Beebe, D.C.5
  • 78
    • 84874272692 scopus 로고    scopus 로고
    • Fgf20 governs formation of primary and secondary dermal condensations in developing hair follicles
    • Huh SH, Närhi K, Lindfors PH, Häärä O, Yang L, Ornitz DM, Mikkola ML. 2013. Fgf20 governs formation of primary and secondary dermal condensations in developing hair follicles. Genes Dev 27: 450-458.
    • (2013) Genes Dev , vol.27 , pp. 450-458
    • Huh, S.H.1    Närhi, K.2    Lindfors, P.H.3    Häärä, O.4    Yang, L.5    Ornitz, D.M.6    Mikkola, M.L.7
  • 80
    • 0038106228 scopus 로고    scopus 로고
    • Regulation of tight junctions during the epithelium-mesen-chyme transition: Direct repression of the gene expression of claudins/occludin by Snail
    • Ikenouchi J, Matsuda M, Furuse M, Tsukita S. 2003. Regulation of tight junctions during the epithelium-mesen-chyme transition: Direct repression of the gene expression of claudins/occludin by Snail. J Cell Sci 116: 1959-1967.
    • (2003) J Cell Sci , vol.116 , pp. 1959-1967
    • Ikenouchi, J.1    Matsuda, M.2    Furuse, M.3    Tsukita, S.4
  • 81
    • 17844405868 scopus 로고    scopus 로고
    • Overexpression of Smad2 reveals its concerted action with Smad4 in regulating TGF-β-mediated epidermal homeostasis
    • Ito Y, Sarkar P, Mi Q, Wu N, Bringas P, Liu Y, Reddy S, Maxson R, Deng C, Chai Y. 2001. Overexpression of Smad2 reveals its concerted action with Smad4 in regulating TGF-β-mediated epidermal homeostasis. Dev Biol 236: 181-194.
    • (2001) Dev Biol , vol.236 , pp. 181-194
    • Ito, Y.1    Sarkar, P.2    Mi, Q.3    Wu, N.4    Bringas, P.5    Liu, Y.6    Reddy, S.7    Maxson, R.8    Deng, C.9    Chai, Y.10
  • 82
    • 28644451449 scopus 로고    scopus 로고
    • Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis
    • Ito M, Liu Y, Yang Z, Nguyen J, Liang F, Morris RJ, Cotsarelis G. 2005. Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat Med 11: 1351-1354.
    • (2005) Nat Med , vol.11 , pp. 1351-1354
    • Ito, M.1    Liu, Y.2    Yang, Z.3    Nguyen, J.4    Liang, F.5    Morris, R.J.6    Cotsarelis, G.7
  • 83
    • 84874548797 scopus 로고    scopus 로고
    • Smad4-Irf6 genetic interaction and TGFβ-mediated IRF6 signaling cascade are crucial for palatal fusion in mice
    • Iwata J, Suzuki A, Pelikan RC, Ho TV, Sanchez-Lara PA, Urata M, Dixon MJ, Chai Y. 2013. Smad4-Irf6 genetic interaction and TGFβ-mediated IRF6 signaling cascade are crucial for palatal fusion in mice. Development 140: 1220-1230.
    • (2013) Development , vol.140 , pp. 1220-1230
    • Iwata, J.1    Suzuki, A.2    Pelikan, R.C.3    Ho, T.V.4    Sanchez-Lara, P.A.5    Urata, M.6    Dixon, M.J.7    Chai, Y.8
  • 84
    • 84893263929 scopus 로고    scopus 로고
    • TGFβ regulates epithelial-mesenchymal interactions through WNT signaling activity to control muscle development in the soft palate
    • Iwata J, Suzuki A, Yokota T, Ho TV, Pelikan R, Urata M, Sanchez-Lara PA, Chai Y. 2014. TGFβ regulates epithelial-mesenchymal interactions through WNT signaling activity to control muscle development in the soft palate. Development 141: 909-917.
    • (2014) Development , vol.141 , pp. 909-917
    • Iwata, J.1    Suzuki, A.2    Yokota, T.3    Ho, T.V.4    Pelikan, R.5    Urata, M.6    Sanchez-Lara, P.A.7    Chai, Y.8
  • 85
    • 0027952727 scopus 로고
    • Expression of transforming growth factor-b2 and b3 mRNAs and proteins in the developing chicken embryo
    • Jakowlew SB, Ciment G, Tuan RS, Sporn MB, Roberts AB. 1994. Expression of transforming growth factor-b2 and b3 mRNAs and proteins in the developing chicken embryo. Differentiation 55: 105-118.
    • (1994) Differentiation , vol.55 , pp. 105-118
    • Jakowlew, S.B.1    Ciment, G.2    Tuan, R.S.3    Sporn, M.B.4    Roberts, A.B.5
  • 86
    • 0037456847 scopus 로고    scopus 로고
    • Links between signal transduction, transcription and adhesion in epithelial bud development
    • Jamora C, DasGupta R, Kocieniewski P, Fuchs E. 2003. Links between signal transduction, transcription and adhesion in epithelial bud development. Nature 422: 317-322.
    • (2003) Nature , vol.422 , pp. 317-322
    • Jamora, C.1    Dasgupta, R.2    Kocieniewski, P.3    Fuchs, E.4
  • 88
    • 84871910395 scopus 로고    scopus 로고
    • A balance of FGF and BMP signals regulates cell cycle exit and equarin expression in lens cells
    • Jarrin M, Pandit T, Gunhaga L. 2012. A balance of FGF and BMP signals regulates cell cycle exit and equarin expression in lens cells. Mol Biol Cell 23: 3266-3274.
    • (2012) Mol Biol Cell , vol.23 , pp. 3266-3274
    • Jarrin, M.1    Pandit, T.2    Gunhaga, L.3
  • 90
    • 57049089995 scopus 로고    scopus 로고
    • Hedgehog signaling in development and cancer
    • Jiang J, Hui CC. 2008. Hedgehog signaling in development and cancer. Dev Cell 15: 801-812.
    • (2008) Dev Cell , vol.15 , pp. 801-812
    • Jiang, J.1    Hui, C.C.2
  • 91
    • 3042616450 scopus 로고    scopus 로고
    • Integument pattern formation involves genetic and epigenetic controls: Feather arrays simulated by digital hormone models
    • Jiang TX, Widelitz RB, Shen WM, Will P, Wu DY, Lin CM, Jung HS, Chuong CM. 2004. Integument pattern formation involves genetic and epigenetic controls: Feather arrays simulated by digital hormone models. Int J Dev Biol 48: 117-135.
    • (2004) Int J Dev Biol , vol.48 , pp. 117-135
    • Jiang, T.X.1    Widelitz, R.B.2    Shen, W.M.3    Will, P.4    Wu, D.Y.5    Lin, C.M.6    Jung, H.S.7    Chuong, C.M.8
  • 92
    • 16244372116 scopus 로고    scopus 로고
    • Foxn1 is required for tissue assembly and desmosomal cadherin expression in the hair shaft
    • Johns SA, Soullier S, Rashbass P, Cunliffe VT. 2005. Foxn1 is required for tissue assembly and desmosomal cadherin expression in the hair shaft. Dev Dyn 232: 1062-1068.
    • (2005) Dev Dyn , vol.232 , pp. 1062-1068
    • Johns, S.A.1    Soullier, S.2    Rashbass, P.3    Cunliffe, V.T.4
  • 95
    • 0028806184 scopus 로고
    • Abnormal lung development and cleft palate in mice lacking TGF-β3 indicates defects of epithelial-mesenchymal interaction
    • Kaartinen V, Voncken JW, Shuler C, Warburton D, Bu D, Heisterkamp N, Groffen J. 1995. Abnormal lung development and cleft palate in mice lacking TGF-β3 indicates defects of epithelial-mesenchymal interaction. Nat Genet 11: 415-421.
    • (1995) Nat Genet , vol.11 , pp. 415-421
    • Kaartinen, V.1    Voncken, J.W.2    Shuler, C.3    Warburton, D.4    Bu, D.5    Heisterkamp, N.6    Groffen, J.7
  • 96
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri R, Weinberg RA. 2009. The basics of epithelial-mesenchymal transition. J Clin Invest 119: 1420-1428.
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 97
    • 84894557023 scopus 로고    scopus 로고
    • Smad1 and 5 but not Smad8 establish stem cell quiescence which is critical to transform the premature hair follicle during morphogenesis toward the postnatal state
    • Kandyba E, Hazen VM, Kobielak A, Butler SJ, Kobielak K. 2014. Smad1 and 5 but not Smad8 establish stem cell quiescence which is critical to transform the premature hair follicle during morphogenesis toward the postnatal state. Stem Cells 32: 534-547.
    • (2014) Stem Cells , vol.32 , pp. 534-547
    • Kandyba, E.1    Hazen, V.M.2    Kobielak, A.3    Butler, S.J.4    Kobielak, K.5
  • 103
    • 0242425844 scopus 로고    scopus 로고
    • Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA
    • Kobielak K, Pasolli HA, Alonso L, Polak L, Fuchs E. 2003. Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA. J Cell Biol 163: 609-623.
    • (2003) J Cell Biol , vol.163 , pp. 609-623
    • Kobielak, K.1    Pasolli, H.A.2    Alonso, L.3    Polak, L.4    Fuchs, E.5
  • 104
    • 0014899784 scopus 로고
    • The induction of hair follicles by embryonic dermal papillae
    • Kollar EJ. 1970. The induction of hair follicles by embryonic dermal papillae. J Invest Dermatol 55: 374-378.
    • (1970) J Invest Dermatol , vol.55 , pp. 374-378
    • Kollar, E.J.1
  • 106
    • 2942536704 scopus 로고    scopus 로고
    • Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor b and bone morphogenetic protein
    • Kowanetz M, Valcourt U, Bergström R, Heldin CH, Moustakas A. 2004. Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor b and bone morphogenetic protein. Mol Cell Biol 24: 4241-4254.
    • (2004) Mol Cell Biol , vol.24 , pp. 4241-4254
    • Kowanetz, M.1    Valcourt, U.2    Bergström, R.3    Heldin, C.H.4    Moustakas, A.5
  • 107
    • 0346458662 scopus 로고    scopus 로고
    • Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1
    • Kuhnert F, Davis CR, Wang HT, Chu P, Lee M, Yuan J, Nusse R, Kuo CJ. 2004. Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1. Proc Natl Acad Sci 101: 266-271.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 266-271
    • Kuhnert, F.1    Davis, C.R.2    Wang, H.T.3    Chu, P.4    Lee, M.5    Yuan, J.6    Nusse, R.7    Kuo, C.J.8
  • 108
    • 0034671830 scopus 로고    scopus 로고
    • Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle
    • Kulessa H, Turk G, Hogan BL. 2000. Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle. EMBO J 19: 6664-6674.
    • (2000) EMBO J , vol.19 , pp. 6664-6674
    • Kulessa, H.1    Turk, G.2    Hogan, B.L.3
  • 109
    • 84894593599 scopus 로고    scopus 로고
    • Molecular mechanisms of epithelial-mesenchymal transition
    • Lamouille S, Xu J, Derynck R. 2014. Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol 15: 178-196.
    • (2014) Nat Rev Mol Cell Biol , vol.15 , pp. 178-196
    • Lamouille, S.1    Xu, J.2    Derynck, R.3
  • 111
    • 84884629522 scopus 로고    scopus 로고
    • Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2
    • Lee YS, Lee SJ. 2013. Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2. Proc Natl Acad Sci 110: E3713-3722.
    • (2013) Proc Natl Acad Sci , vol.110 , pp. E3713-E3722
    • Lee, Y.S.1    Lee, S.J.2
  • 112
    • 85006317022 scopus 로고    scopus 로고
    • Roles of GASP-1 and GDF-11 in dental and craniofacial development
    • Lee YS, Lee SJ. 2015. Roles of GASP-1 and GDF-11 in dental and craniofacial development. J Oral Med Pain 40: 110- 114.
    • (2015) J Oral Med Pain , vol.40 , pp. 110-114
    • Lee, Y.S.1    Lee, S.J.2
  • 113
    • 83455182064 scopus 로고    scopus 로고
    • Crosstalk between nuclear factor I-C and transforming growth factor-b1 signaling regulates odontoblast differentiation and homeostasis
    • Lee DS, Yoon WJ, Cho ES, Kim HJ, Gronostajski RM, Cho MI, Park JC. 2011. Crosstalk between nuclear factor I-C and transforming growth factor-b1 signaling regulates odontoblast differentiation and homeostasis. PLoS ONE 6: e29160.
    • (2011) Plos ONE , vol.6
    • Lee, D.S.1    Yoon, W.J.2    Cho, E.S.3    Kim, H.J.4    Gronostajski, R.M.5    Cho, M.I.6    Park, J.C.7
  • 114
    • 84881048357 scopus 로고    scopus 로고
    • TGF-β1 regulates cell fate during epithelial-mesenchymal transition by upregulat-ing survivin
    • Lee J, Choi JH, Joo CK. 2013. TGF-β1 regulates cell fate during epithelial-mesenchymal transition by upregulat-ing survivin. Cell Death Dis 4: e714.
    • (2013) Cell Death Dis , vol.4
    • Lee, J.1    Choi, J.H.2    Joo, C.K.3
  • 115
    • 84964413603 scopus 로고    scopus 로고
    • Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis
    • Lee J, Kang S, Lilja KC, Colletier KJ, Scheitz CJ, Zhang YV, Tumbar T. 2016. Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis. Nat Commun 7: 11278.
    • (2016) Nat Commun , vol.7
    • Lee, J.1    Kang, S.2    Lilja, K.C.3    Colletier, K.J.4    Scheitz, C.J.5    Zhang, Y.V.6    Tumbar, T.7
  • 116
    • 28444472423 scopus 로고    scopus 로고
    • Distinct stem cell populations regenerate the follicle and interfol-licular epidermis
    • Levy V, Lindon C, Harfe BD, Morgan BA. 2005. Distinct stem cell populations regenerate the follicle and interfol-licular epidermis. Dev Cell 9: 855-861.
    • (2005) Dev Cell , vol.9 , pp. 855-861
    • Levy, V.1    Lindon, C.2    Harfe, B.D.3    Morgan, B.A.4
  • 117
    • 80051519486 scopus 로고    scopus 로고
    • Snail involves in the transforming growth factor b1-mediated epithelial- mesenchymal transition of retinal pigment epithelial cells
    • Li H, Wang H, Wang F, Gu Q, Xu X. 2011. Snail involves in the transforming growth factor b1-mediated epithelial- mesenchymal transition of retinal pigment epithelial cells. PLoS ONE 6: e23322.
    • (2011) Plos ONE , vol.6
    • Li, H.1    Wang, H.2    Wang, F.3    Gu, Q.4    Xu, X.5
  • 118
    • 84930637536 scopus 로고    scopus 로고
    • BMP-2 is involved in scleral remodeling in myopia development
    • Li H, Cui D, Zhao F, Huo L, Hu J, Zeng J. 2015a. BMP-2 is involved in scleral remodeling in myopia development. PLoS ONE 10: e0125219.
    • (2015) Plos ONE , vol.10
    • Li, H.1    Cui, D.2    Zhao, F.3    Huo, L.4    Hu, J.5    Zeng, J.6
  • 119
    • 84928092998 scopus 로고    scopus 로고
    • BMP-SHH signaling network controls epithelial stem cell fate via regulation of its niche in the developing tooth
    • Li J, Feng J, Liu Y, Ho TV, Grimes W, Ho HA, Park S, Wang S, Chai Y. 2015b. BMP-SHH signaling network controls epithelial stem cell fate via regulation of its niche in the developing tooth. Dev Cell 33: 125-135.
    • (2015) Dev Cell , vol.33 , pp. 125-135
    • Li, J.1    Feng, J.2    Liu, Y.3    Ho, T.V.4    Grimes, W.5    Ho, H.A.6    Park, S.7    Wang, S.8    Chai, Y.9
  • 120
    • 84957597219 scopus 로고    scopus 로고
    • Epidermal b-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages
    • Lichtenberger BM, Mastrogiannaki M, Watt FM. 2016. Epidermal b-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages. Nat Commun 7: 10537.
    • (2016) Nat Commun , vol.7
    • Lichtenberger, B.M.1    Mastrogiannaki, M.2    Watt, F.M.3
  • 121
    • 84865839326 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions: Insights from development
    • Lim J, Thiery JP. 2012. Epithelial-mesenchymal transitions: Insights from development. Development 139: 3471- 3486.
    • (2012) Development , vol.139 , pp. 3471-3486
    • Lim, J.1    Thiery, J.P.2
  • 122
    • 0035979272 scopus 로고    scopus 로고
    • Conditional epidermal expression of TGFβ 1 blocks neonatal lethality but causes a reversible hyperplasia and alopecia
    • Liu X, Alexander V, Vijayachandra K, Bhogte E, Diamond I, Glick A. 2001. Conditional epidermal expression of TGFβ 1 blocks neonatal lethality but causes a reversible hyperplasia and alopecia. Proc Natl Acad Sci 98: 9139- 9144.
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 9139-9144
    • Liu, X.1    Alexander, V.2    Vijayachandra, K.3    Bhogte, E.4    Diamond, I.5    Glick, A.6
  • 124
    • 0024991197 scopus 로고
    • Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2A (BMP-2A)
    • Lyons KM, Pelton RW, Hogan BL. 1990. Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2A (BMP-2A). Development 109: 833-844.
    • (1990) Development , vol.109 , pp. 833-844
    • Lyons, K.M.1    Pelton, R.W.2    Hogan, B.L.3
  • 126
    • 84866742560 scopus 로고    scopus 로고
    • TGFβ signalling in context
    • Massagué J. 2012. TGFβ signalling in context. Nat Rev Mol Cell Biol 13: 616-630.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 616-630
    • Massagué, J.1
  • 127
    • 1242307432 scopus 로고    scopus 로고
    • Nodal and Fgf pathways interact through a positive regulatory loop and synergize to maintain mesodermal cell populations
    • Mathieu J, Griffin K, Herbomel P, Dickmeis T, Strahle U, Kimelman D, Rosa FM, Peyrieras N. 2004. Nodal and Fgf pathways interact through a positive regulatory loop and synergize to maintain mesodermal cell populations. Development 131: 629-641.
    • (2004) Development , vol.131 , pp. 629-641
    • Mathieu, J.1    Griffin, K.2    Herbomel, P.3    Dickmeis, T.4    Strahle, U.5    Kimelman, D.6    Rosa, F.M.7    Peyrieras, N.8
  • 128
    • 0029026264 scopus 로고
    • Functional analysis of mammalian members of the transforming growth factor-b superfamily
    • Matzuk MM. 1995. Functional analysis of mammalian members of the transforming growth factor-b superfamily. Trends Endocrinol Metab 6: 120-127.
    • (1995) Trends Endocrinol Metab , vol.6 , pp. 120-127
    • Matzuk, M.M.1
  • 129
    • 0028918915 scopus 로고
    • Multiple defects and perinatal death in mice deficient in follistatin
    • Matzuk MM, Lu N, Vogel H, Sellheyer K, Roop DR, Bradley A. 1995. Multiple defects and perinatal death in mice deficient in follistatin. Nature 374: 360-363.
    • (1995) Nature , vol.374 , pp. 360-363
    • Matzuk, M.M.1    Lu, N.2    Vogel, H.3    Sellheyer, K.4    Roop, D.R.5    Bradley, A.6
  • 130
    • 0032722830 scopus 로고    scopus 로고
    • Whn and mHa3 are components of the genetic hierarchy controlling hair follicle differentiation
    • Meier N, Dear TN, Boehm T. 1999. Whn and mHa3 are components of the genetic hierarchy controlling hair follicle differentiation. Mech Dev 89: 215-221.
    • (1999) Mech Dev , vol.89 , pp. 215-221
    • Meier, N.1    Dear, T.N.2    Boehm, T.3
  • 131
    • 34250695906 scopus 로고    scopus 로고
    • Multiple transforming growth factor-b isoforms and receptors function during epithelial-mesenchymal cell transformation in the embryonic heart
    • Mercado-Pimentel ME, Runyan RB. 2007. Multiple transforming growth factor-b isoforms and receptors function during epithelial-mesenchymal cell transformation in the embryonic heart. Cells Tissues Organs 185: 146-156.
    • (2007) Cells Tissues Organs , vol.185 , pp. 146-156
    • Mercado-Pimentel, M.E.1    Runyan, R.B.2
  • 133
    • 0028603343 scopus 로고
    • TGF-β induced transdifferentiation of mammary epithelial cells to mesenchymal cells: Involvement of type I receptors
    • Miettinen PJ, Ebner R, Lopez AR, Derynck R. 1994. TGF-β induced transdifferentiation of mammary epithelial cells to mesenchymal cells: Involvement of type I receptors. J Cell Biol 127: 2021-2036.
    • (1994) J Cell Biol , vol.127 , pp. 2021-2036
    • Miettinen, P.J.1    Ebner, R.2    Lopez, A.R.3    Derynck, R.4
  • 134
    • 2942580631 scopus 로고    scopus 로고
    • Essential roles of BMPR-IA signaling in differentiation and growth of hair follicles and in skin tumorigenesis
    • Ming Kwan K, Wurst W, Behringer RR. 2004. Essential roles of BMPR-IA signaling in differentiation and growth of hair follicles and in skin tumorigenesis. Genesis 39: 10-25.
    • (2004) Genesis , vol.39 , pp. 10-25
    • Ming Kwan, K.1    Wurst, W.2    Behringer, R.R.3
  • 136
    • 33645469482 scopus 로고    scopus 로고
    • Stem cells and their niches
    • Moore KA, Lemischka IR. 2006. Stem cells and their niches. Science 311: 1880-1885.
    • (2006) Science , vol.311 , pp. 1880-1885
    • Moore, K.A.1    Lemischka, I.R.2
  • 137
    • 21644485644 scopus 로고    scopus 로고
    • A perspective on keratinocyte stem cells as targets for skin carcinogenesis
    • Morris RJ. 2004. A perspective on keratinocyte stem cells as targets for skin carcinogenesis. Differentiation 72: 381- 386.
    • (2004) Differentiation , vol.72 , pp. 381-386
    • Morris, R.J.1
  • 140
    • 0033214191 scopus 로고    scopus 로고
    • Overexpression of activin A in the skin of transgenic mice reveals new activities of activin in epidermal morphogenesis, dermal fibrosis and wound repair
    • Munz B, Smola H, Engelhardt F, Bleuel K, Brauchle M, Lein I, Evans LW, Huylebroeck D, Balling R, Werner S. 1999. Overexpression of activin A in the skin of transgenic mice reveals new activities of activin in epidermal morphogenesis, dermal fibrosis and wound repair. EMBO J 18: 5205-5215.
    • (1999) EMBO J , vol.18 , pp. 5205-5215
    • Munz, B.1    Smola, H.2    Engelhardt, F.3    Bleuel, K.4    Brauchle, M.5    Lein, I.6    Evans, L.W.7    Huylebroeck, D.8    Balling, R.9    Werner, S.10
  • 142
    • 0031706575 scopus 로고    scopus 로고
    • Neural crest emigration from the neural tube depends on regulated cadherin expression
    • Nakagawa S, Takeichi M. 1998. Neural crest emigration from the neural tube depends on regulated cadherin expression. Development 125: 2963-2971.
    • (1998) Development , vol.125 , pp. 2963-2971
    • Nakagawa, S.1    Takeichi, M.2
  • 143
    • 0037364579 scopus 로고    scopus 로고
    • Control of pelage hair follicle development and cycling by complex interactions between follistatin and activin
    • Nakamura M, Matzuk MM, Gerstmayer B, Bosio A, Lauster R, Miyachi Y, Werner S, Paus R. 2003. Control of pelage hair follicle development and cycling by complex interactions between follistatin and activin. FASEB J 17: 497- 499.
    • (2003) FASEB J , vol.17 , pp. 497-499
    • Nakamura, M.1    Matzuk, M.M.2    Gerstmayer, B.3    Bosio, A.4    Lauster, R.5    Miyachi, Y.6    Werner, S.7    Paus, R.8
  • 144
    • 34249674558 scopus 로고    scopus 로고
    • TGFβ3 inhibits E-cadherin gene expression in palate medial-edge epithelial cells through a Smad2-Smad4-LEF1 transcription complex
    • Nawshad A, Medici D, Liu CC, Hay ED. 2007. TGFβ3 inhibits E-cadherin gene expression in palate medial-edge epithelial cells through a Smad2-Smad4-LEF1 transcription complex. J Cell Sci 120: 1646-1653.
    • (2007) J Cell Sci , vol.120 , pp. 1646-1653
    • Nawshad, A.1    Medici, D.2    Liu, C.C.3    Hay, E.D.4
  • 145
    • 77951238830 scopus 로고    scopus 로고
    • Remodeling epithelial cell organization: Transitions between front-rear and apical-basal polarity
    • Nelson WJ. 2009. Remodeling epithelial cell organization: Transitions between front-rear and apical-basal polarity. Cold Spring Harb Perspect Biol 1: a000513.
    • (2009) Cold Spring Harb Perspect Biol , vol.1
    • Nelson, W.J.1
  • 146
    • 84887273608 scopus 로고    scopus 로고
    • Epithelial plasticity: A common theme in embryonic and cancer cells
    • Nieto MA. 2013. Epithelial plasticity: A common theme in embryonic and cancer cells. Science 342: 1234850.
    • (2013) Science , vol.342
    • Nieto, M.A.1
  • 148
    • 84932095270 scopus 로고    scopus 로고
    • Constitutively active mutation of ACVR1 in oral epithelium causes submu-cous cleft palate in mice
    • Noda K, Mishina Y, Komatsu Y. 2015. Constitutively active mutation of ACVR1 in oral epithelium causes submu-cous cleft palate in mice. Dev Biol 415: 306-313.
    • (2015) Dev Biol , vol.415 , pp. 306-313
    • Noda, K.1    Mishina, Y.2    Komatsu, Y.3
  • 149
    • 42049113862 scopus 로고    scopus 로고
    • Follistatin antagonizes transforming growth factor-b3-induced epithelial-mesenchymal transition in vitro: Implications for murine palatal development supported by microarray analysis
    • Nogai H, Rosowski M, Grun J, Rietz A, Debus N, Schmidt G, Lauster C, Janitz M, Vortkamp A, Lauster R. 2008. Follistatin antagonizes transforming growth factor-b3-induced epithelial-mesenchymal transition in vitro: Implications for murine palatal development supported by microarray analysis. Differentiation 76: 404-416.
    • (2008) Differentiation , vol.76 , pp. 404-416
    • Nogai, H.1    Rosowski, M.2    Grun, J.3    Rietz, A.4    Debus, N.5    Schmidt, G.6    Lauster, C.7    Janitz, M.8    Vortkamp, A.9    Lauster, R.10
  • 150
    • 0031767259 scopus 로고    scopus 로고
    • BMPs mediate lateral inhibition at successive stages in feather tract development
    • Noramly S, Morgan BA. 1998. BMPs mediate lateral inhibition at successive stages in feather tract development. Development 125: 3775-3787.
    • (1998) Development , vol.125 , pp. 3775-3787
    • Noramly, S.1    Morgan, B.A.2
  • 151
    • 84922723265 scopus 로고    scopus 로고
    • Sox5 is a DNA-binding cofactor for BMP R-Smads that directs target specificity during patterning of the early ectoderm
    • Nordin K, LaBonne C. 2014. Sox5 is a DNA-binding cofactor for BMP R-Smads that directs target specificity during patterning of the early ectoderm. Dev Cell 31: 374-382.
    • (2014) Dev Cell , vol.31 , pp. 374-382
    • Nordin, K.1    Labonne, C.2
  • 153
    • 0035139735 scopus 로고    scopus 로고
    • Differential expression of two BMP antagonists, gremlin and follistatin, during development of the chick feather bud
    • Ohyama A, Saito F, Ohuchi H, Noji S. 2001. Differential expression of two BMP antagonists, gremlin and follistatin, during development of the chick feather bud. Mech Dev 100: 331-333.
    • (2001) Mech Dev , vol.100 , pp. 331-333
    • Ohyama, A.1    Saito, F.2    Ohuchi, H.3    Noji, S.4
  • 154
    • 34248645942 scopus 로고    scopus 로고
    • Cell autonomous requirement for TGF-β signaling during odontoblast differentiation and dentin matrix formation
    • Oka S, Oka K, Xu X, Sasaki T, Bringas P Jr, Chai Y. 2007. Cell autonomous requirement for TGF-β signaling during odontoblast differentiation and dentin matrix formation. Mech Dev 124: 409-415.
    • (2007) Mech Dev , vol.124 , pp. 409-415
    • Oka, S.1    Oka, K.2    Xu, X.3    Sasaki, T.4    Bringas, P.5    Chai, Y.6
  • 155
    • 84855486150 scopus 로고    scopus 로고
    • Paracrine TGF-β signaling counterbalances BMP-mediated repression in hair follicle stem cell activation
    • Oshimori N, Fuchs E. 2012. Paracrine TGF-β signaling counterbalances BMP-mediated repression in hair follicle stem cell activation. Cell Stem Cell 10: 63-75.
    • (2012) Cell Stem Cell , vol.10 , pp. 63-75
    • Oshimori, N.1    Fuchs, E.2
  • 156
    • 84929191594 scopus 로고    scopus 로고
    • Neural retina identity is specified by lens-derived BMP signals
    • Pandit T, Jidigam VK, Patthey C, Gunhaga L. 2015. Neural retina identity is specified by lens-derived BMP signals. Development 142: 1850-1859.
    • (2015) Development , vol.142 , pp. 1850-1859
    • Pandit, T.1    Jidigam, V.K.2    Patthey, C.3    Gunhaga, L.4
  • 157
    • 77955745784 scopus 로고    scopus 로고
    • Cadherin 6B induces BMP signaling and de-epithelialization during the epithelial mesenchymal transition of the neural crest
    • Park KS, Gumbiner BM. 2010. Cadherin 6B induces BMP signaling and de-epithelialization during the epithelial mesenchymal transition of the neural crest. Development 137: 2691-2701.
    • (2010) Development , vol.137 , pp. 2691-2701
    • Park, K.S.1    Gumbiner, B.M.2
  • 158
    • 84861222173 scopus 로고    scopus 로고
    • Cadherin-6B stimulates an epithelial mesenchymal transition and the delamination of cells from the neural ectoderm via LIMK/cofilin mediated non-canonical BMP receptor signaling
    • Park KS, Gumbiner BM. 2012. Cadherin-6B stimulates an epithelial mesenchymal transition and the delamination of cells from the neural ectoderm via LIMK/cofilin mediated non-canonical BMP receptor signaling. Dev Biol 366: 232-243.
    • (2012) Dev Biol , vol.366 , pp. 232-243
    • Park, K.S.1    Gumbiner, B.M.2
  • 159
    • 0032780157 scopus 로고    scopus 로고
    • The role of long range, local and direct signalling molecules during chick feather bud development involving the BMPs, follistatin and the Eph receptor tyrosine kinase Eph-A4
    • Patel K, Makarenkova H, Jung HS. 1999. The role of long range, local and direct signalling molecules during chick feather bud development involving the BMPs, follistatin and the Eph receptor tyrosine kinase Eph-A4. Mech Dev 86: 51-62.
    • (1999) Mech Dev , vol.86 , pp. 51-62
    • Patel, K.1    Makarenkova, H.2    Jung, H.S.3
  • 160
    • 84892548031 scopus 로고    scopus 로고
    • Signaling pathways regulating ectodermal cell fate choices
    • Patthey C, Gunhaga L. 2014. Signaling pathways regulating ectodermal cell fate choices. Exp Cell Res 321: 11-16.
    • (2014) Exp Cell Res , vol.321 , pp. 11-16
    • Patthey, C.1    Gunhaga, L.2
  • 161
    • 34249289041 scopus 로고    scopus 로고
    • Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
    • Peinado H, Olmeda D, Cano A. 2007. Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype? Nat Rev Cancer 7: 415-428.
    • (2007) Nat Rev Cancer , vol.7 , pp. 415-428
    • Peinado, H.1    Olmeda, D.2    Cano, A.3
  • 162
    • 0025018368 scopus 로고
    • Differential expression of genes encoding TGFs b1, b2, and b3 during murine palate formation
    • Pelton RW, Hogan BL, Miller DA, Moses HL. 1990. Differential expression of genes encoding TGFs b1, b2, and b3 during murine palate formation. Dev Biol 141: 456-460.
    • (1990) Dev Biol , vol.141 , pp. 456-460
    • Pelton, R.W.1    Hogan, B.L.2    Miller, D.A.3    Moses, H.L.4
  • 164
    • 0037829660 scopus 로고    scopus 로고
    • Canonical Wnt signals are essential for homeostasis of the intestinal epithelium
    • Pinto D, Gregorieff A, Begthel H, Clevers H. 2003. Canonical Wnt signals are essential for homeostasis of the intestinal epithelium. Genes Dev 17: 1709-1713.
    • (2003) Genes Dev , vol.17 , pp. 1709-1713
    • Pinto, D.1    Gregorieff, A.2    Begthel, H.3    Clevers, H.4
  • 167
    • 30544444184 scopus 로고    scopus 로고
    • Hair follicle defects and squamous cell carcinoma formation in Smad4 conditional knockout mouse skin
    • Qiao W, Li AG, Owens P, Xu X, Wang XJ, Deng CX. 2006. Hair follicle defects and squamous cell carcinoma formation in Smad4 conditional knockout mouse skin. Oncogene 25: 207-217.
    • (2006) Oncogene , vol.25 , pp. 207-217
    • Qiao, W.1    Li, A.G.2    Owens, P.3    Xu, X.4    Wang, X.J.5    Deng, C.X.6
  • 168
    • 0036038264 scopus 로고    scopus 로고
    • Ultraviolet irradiation alters transforming growth factor b/ Smad pathway in human skin in vivo
    • Quan T, He T, Kang S, Voorhees JJ, Fisher GJ. 2002. Ultraviolet irradiation alters transforming growth factor b/ Smad pathway in human skin in vivo. J Invest Dermatol 119: 499-506.
    • (2002) J Invest Dermatol , vol.119 , pp. 499-506
    • Quan, T.1    He, T.2    Kang, S.3    Voorhees, J.J.4    Fisher, G.J.5
  • 170
    • 39449112659 scopus 로고    scopus 로고
    • BMP signaling in dermal papilla cells is required for their hair follicle-inductive properties
    • Rendl M, Polak L, Fuchs E. 2008. BMP signaling in dermal papilla cells is required for their hair follicle-inductive properties. Genes Dev 22: 543-557.
    • (2008) Genes Dev , vol.22 , pp. 543-557
    • Rendl, M.1    Polak, L.2    Fuchs, E.3
  • 172
    • 84904461158 scopus 로고    scopus 로고
    • Dose-dependent Nodal/Smad signals pattern the early mouse embryo
    • Robertson EJ. 2014. Dose-dependent Nodal/Smad signals pattern the early mouse embryo. Semin Cell Dev Biol 32: 73-79.
    • (2014) Semin Cell Dev Biol , vol.32 , pp. 73-79
    • Robertson, E.J.1
  • 173
    • 84890826207 scopus 로고    scopus 로고
    • Sip1 mediates an E-cadherin-to-N-cadherin switch during cranial neural crest EMT
    • Rogers CD, Saxena A, Bronner ME. 2013. Sip1 mediates an E-cadherin-to-N-cadherin switch during cranial neural crest EMT. J Cell Biol 203: 835-847.
    • (2013) J Cell Biol , vol.203 , pp. 835-847
    • Rogers, C.D.1    Saxena, A.2    Bronner, M.E.3
  • 175
    • 84886950363 scopus 로고    scopus 로고
    • Spatial organization within a niche as a determinant of stem-cell fate
    • Rompolas P, Mesa KR, Greco V. 2013. Spatial organization within a niche as a determinant of stem-cell fate. Nature 502: 513-518.
    • (2013) Nature , vol.502 , pp. 513-518
    • Rompolas, P.1    Mesa, K.R.2    Greco, V.3
  • 178
    • 33644831172 scopus 로고    scopus 로고
    • Adenoviral gene transfer of BMP-7, Id2, or Id3 suppresses injury-induced epithelial-to-mesenchymal transition of lens epithelium in mice
    • Saika S, Ikeda K, Yamanaka O, Flanders KC, Ohnishi Y, Nakajima Y, Muragaki Y, Ooshima A. 2006. Adenoviral gene transfer of BMP-7, Id2, or Id3 suppresses injury-induced epithelial-to-mesenchymal transition of lens epithelium in mice. Am J Physiol Cell Physiol 290: C282-289.
    • (2006) Am J Physiol Cell Physiol , vol.290 , pp. C282-C289
    • Saika, S.1    Ikeda, K.2    Yamanaka, O.3    Flanders, K.C.4    Ohnishi, Y.5    Nakajima, Y.6    Muragaki, Y.7    Ooshima, A.8
  • 179
    • 33646137784 scopus 로고    scopus 로고
    • Cooperative action of Sox9, Snail2 and PKA signaling in early neural crest development
    • Sakai D, Suzuki T, Osumi N, Wakamatsu Y. 2006. Cooperative action of Sox9, Snail2 and PKA signaling in early neural crest development. Development 133: 1323-1333.
    • (2006) Development , vol.133 , pp. 1323-1333
    • Sakai, D.1    Suzuki, T.2    Osumi, N.3    Wakamatsu, Y.4
  • 181
    • 84897125705 scopus 로고    scopus 로고
    • Rethinking differentiation: Stem cells, regeneration, and plasticity
    • Sanchez-Alvarado A, Yamanaka S. 2014. Rethinking differentiation: Stem cells, regeneration, and plasticity. Cell 157: 110-119.
    • (2014) Cell , vol.157 , pp. 110-119
    • Sanchez-Alvarado, A.1    Yamanaka, S.2
  • 182
    • 45849102001 scopus 로고    scopus 로고
    • A gene regulatory network orchestrates neural crest formation
    • Sauka-Spengler T, Bronner-Fraser M. 2008. A gene regulatory network orchestrates neural crest formation. Nat Rev Mol Cell Biol 9: 557-568.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 557-568
    • Sauka-Spengler, T.1    Bronner-Fraser, M.2
  • 184
    • 0345255908 scopus 로고    scopus 로고
    • Nodal signaling in vertebrate development
    • Schier AF. 2003. Nodal signaling in vertebrate development. Annu Rev Cell Dev Biol 19: 589-621.
    • (2003) Annu Rev Cell Dev Biol , vol.19 , pp. 589-621
    • Schier, A.F.1
  • 185
    • 0032757875 scopus 로고    scopus 로고
    • Regulation of the onset of neural crest migration by coordinated activity of BMP4 and noggin in the dorsal neural tube
    • Sela-Donenfeld D and Kalcheim C. 1999. Regulation of the onset of neural crest migration by coordinated activity of BMP4 and noggin in the dorsal neural tube. Development 126: 4749-4762.
    • (1999) Development , vol.126 , pp. 4749-4762
    • Sela-Donenfeld, D.1    Kalcheim, C.2
  • 186
    • 0033639030 scopus 로고    scopus 로고
    • Inhibition of noggin expression in the dorsal neural tube by somitogenesis: A mechanism for coordinating the timing of neural crest emigration
    • Sela-Donenfeld D, Kalcheim C. 2000. Inhibition of noggin expression in the dorsal neural tube by somitogenesis: A mechanism for coordinating the timing of neural crest emigration. Development 127: 4845-4854.
    • (2000) Development , vol.127 , pp. 4845-4854
    • Sela-Donenfeld, D.1    Kalcheim, C.2
  • 188
    • 0025287890 scopus 로고
    • Pattern formation in skin development
    • Sengel P. 1990. Pattern formation in skin development. Int J Dev Biol 34: 33-50.
    • (1990) Int J Dev Biol , vol.34 , pp. 33-50
    • Sengel, P.1
  • 191
    • 84904513934 scopus 로고    scopus 로고
    • TGFβ signaling in establishing left-right asymmetry
    • Shiratori H, Hamada H. 2014. TGFβ signaling in establishing left-right asymmetry. Semin Cell Dev Biol 32: 80-84.
    • (2014) Semin Cell Dev Biol , vol.32 , pp. 80-84
    • Shiratori, H.1    Hamada, H.2
  • 194
    • 33845301220 scopus 로고    scopus 로고
    • WNTand DKK determine hair follicle spacing through a reaction-diffu-sion mechanism
    • Sick S, Reinker S, Timmer J, Schlake T. 2006. WNTand DKK determine hair follicle spacing through a reaction-diffu-sion mechanism. Science 314: 1447-1450.
    • (2006) Science , vol.314 , pp. 1447-1450
    • Sick, S.1    Reinker, S.2    Timmer, J.3    Schlake, T.4
  • 195
    • 0034891214 scopus 로고    scopus 로고
    • Interactions between Wnt and Vg1 signalling pathways initiate primitive streak formation in the chick embryo
    • Skromne I, Stern CD. 2001. Interactions between Wnt and Vg1 signalling pathways initiate primitive streak formation in the chick embryo. Development 128: 2915-2927.
    • (2001) Development , vol.128 , pp. 2915-2927
    • Skromne, I.1    Stern, C.D.2
  • 197
    • 19744364989 scopus 로고    scopus 로고
    • Neural induction: Old problem, new findings, yet more questions
    • Stern CD. 2005. Neural induction: Old problem, new findings, yet more questions. Development 132: 2007-2021.
    • (2005) Development , vol.132 , pp. 2007-2021
    • Stern, C.D.1
  • 199
    • 84887456252 scopus 로고    scopus 로고
    • The epigenetics of epithelial- mesenchymal plasticity in cancer
    • Tam WL, Weinberg RA. 2013. The epigenetics of epithelial- mesenchymal plasticity in cancer. Nat Med 19: 1438- 1449.
    • (2013) Nat Med , vol.19 , pp. 1438-1449
    • Tam, W.L.1    Weinberg, R.A.2
  • 200
    • 0030296921 scopus 로고    scopus 로고
    • Local delivery of TGF b2 can substitute for placode epithelium to induce mesenchymal condensation during skin appendage morphogenesis
    • Ting-Berreth SA, Chuong CM. 1996. Local delivery of TGF b2 can substitute for placode epithelium to induce mesenchymal condensation during skin appendage morphogenesis. Dev Biol 179: 347-359.
    • (1996) Dev Biol , vol.179 , pp. 347-359
    • Ting-Berreth, S.A.1    Chuong, C.M.2
  • 201
    • 0034990885 scopus 로고    scopus 로고
    • Overexpres- sion of Hoxc13 in differentiating keratinocytes results in downregulation of a novel hair keratin gene cluster and alopecia
    • Tkatchenko AV, Visconti RP, Shang L, Papenbrock T, Pruett ND, Ito T, Ogawa M, Awgulewitsch A. 2001. Overexpres- sion of Hoxc13 in differentiating keratinocytes results in downregulation of a novel hair keratin gene cluster and alopecia. Development 128: 1547-1558.
    • (2001) Development , vol.128 , pp. 1547-1558
    • Tkatchenko, A.V.1    Visconti, R.P.2    Shang, L.3    Papenbrock, T.4    Pruett, N.D.5    Ito, T.6    Ogawa, M.7    Awgulewitsch, A.8
  • 203
    • 77949462780 scopus 로고    scopus 로고
    • The RhoA activator GEF-H1/Lfc is a transforming growth factor-b target gene and effector that regulates a-smooth muscle actin expression and cell migration
    • Tsapara A, Luthert P, Greenwood J, Hill CS, Matter K, Balda MS. 2010. The RhoA activator GEF-H1/Lfc is a transforming growth factor-b target gene and effector that regulates a-smooth muscle actin expression and cell migration. Mol Biol Cell 21: 860-870.
    • (2010) Mol Biol Cell , vol.21 , pp. 860-870
    • Tsapara, A.1    Luthert, P.2    Greenwood, J.3    Hill, C.S.4    Matter, K.5    Balda, M.S.6
  • 205
    • 16344378397 scopus 로고    scopus 로고
    • TGF-β and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition
    • Valcourt U, Kowanetz M, Niimi H, Heldin CH, Moustakas A. 2005. TGF-β and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition. Mol Biol Cell 16: 1987-2002.
    • (2005) Mol Biol Cell , vol.16 , pp. 1987-2002
    • Valcourt, U.1    Kowanetz, M.2    Niimi, H.3    Heldin, C.H.4    Moustakas, A.5
  • 206
    • 0032124524 scopus 로고    scopus 로고
    • Xenopus cadherin-11 is expressed in different populations of migrating neural crest cells
    • Vallin J, Girault JM, Thiery JP, Broders F. 1998. Xenopus cadherin-11 is expressed in different populations of migrating neural crest cells. Mech Dev 75: 171-174.
    • (1998) Mech Dev , vol.75 , pp. 171-174
    • Vallin, J.1    Girault, J.M.2    Thiery, J.P.3    Broders, F.4
  • 207
    • 0027945654 scopus 로고
    • Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice
    • van Genderen C, Okamura RM, Fariñas I, Quo RG, Parslow TG, Bruhn L, Grosschedl R. 1994. Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice. Genes Dev 8: 2691-2703.
    • (1994) Genes Dev , vol.8 , pp. 2691-2703
    • Van Genderen, C.1    Okamura, R.M.2    Fariñas, I.3    Quo, R.G.4    Parslow, T.G.5    Bruhn, L.6    Grosschedl, R.7
  • 208
    • 0030932236 scopus 로고    scopus 로고
    • Nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation
    • Varlet I, Collignon J, Robertson EJ. 1997. Nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation. Development 124: 1033-1044.
    • (1997) Development , vol.124 , pp. 1033-1044
    • Varlet, I.1    Collignon, J.2    Robertson, E.J.3
  • 211
    • 0030953639 scopus 로고    scopus 로고
    • Expression of a dominant-negative type II transforming growth factor b (TGF-β) receptor in the epidermis of transgenic mice blocks TGF-β-mediated growth inhibition
    • Wang XJ, Greenhalgh DA, Bickenbach JR, Jiang A, Bundman DS, Krieg T, Derynck R, Roop DR. 1997. Expression of a dominant-negative type II transforming growth factor b (TGF-β) receptor in the epidermis of transgenic mice blocks TGF-β-mediated growth inhibition. Proc Natl Acad Sci 94: 2386-2391.
    • (1997) Proc Natl Acad Sci , vol.94 , pp. 2386-2391
    • Wang, X.J.1    Greenhalgh, D.A.2    Bickenbach, J.R.3    Jiang, A.4    Bundman, D.S.5    Krieg, T.6    Derynck, R.7    Roop, D.R.8
  • 212
    • 0033587687 scopus 로고    scopus 로고
    • Development of gene-switch transgenic mice that indu-cibly express transforming growth factor b1 in the epidermis
    • Wang XJ, Liefer KM, Tsai S, O’Malley BW, Roop DR. 1999. Development of gene-switch transgenic mice that indu-cibly express transforming growth factor b1 in the epidermis. Proc Natl Acad Sci 96: 8483-8488.
    • (1999) Proc Natl Acad Sci , vol.96 , pp. 8483-8488
    • Wang, X.J.1    Liefer, K.M.2    Tsai, S.3    O’Malley, B.W.4    Roop, D.R.5
  • 214
    • 84864130274 scopus 로고    scopus 로고
    • BMP activity is required for tooth development from the lamina to bud stage
    • Wang Y, Li L, Zheng Y, Yuan G, Yang G, He F, Chen Y. 2012. BMP activity is required for tooth development from the lamina to bud stage. J Dent Res 91: 690-695.
    • (2012) J Dent Res , vol.91 , pp. 690-695
    • Wang, Y.1    Li, L.2    Zheng, Y.3    Yuan, G.4    Yang, G.5    He, F.6    Chen, Y.7
  • 215
    • 84957574623 scopus 로고    scopus 로고
    • Foxc1 reinforces quiescence in self-renewing hair follicle stem cells
    • Wang L, Siegenthaler JA, Dowell RD, Yi R. 2016. Foxc1 reinforces quiescence in self-renewing hair follicle stem cells. Science 351: 613-617.
    • (2016) Science , vol.351 , pp. 613-617
    • Wang, L.1    Siegenthaler, J.A.2    Dowell, R.D.3    Yi, R.4
  • 216
    • 58149239733 scopus 로고    scopus 로고
    • Roles of TGF-β family signaling in stem cell renewal and differentiation
    • Watabe T, Miyazono K. 2009. Roles of TGF-β family signaling in stem cell renewal and differentiation. Cell Res 19: 103-115.
    • (2009) Cell Res , vol.19 , pp. 103-115
    • Watabe, T.1    Miyazono, K.2
  • 218
    • 45549105086 scopus 로고    scopus 로고
    • The transcription factor snail represses Crumbs3 expression and disrupts apico-basal polarity complexes
    • Whiteman EL, Liu CJ, Fearon ER, Margolis B. 2008. The transcription factor snail represses Crumbs3 expression and disrupts apico-basal polarity complexes. Oncogene 27: 3875-3879.
    • (2008) Oncogene , vol.27 , pp. 3875-3879
    • Whiteman, E.L.1    Liu, C.J.2    Fearon, E.R.3    Margolis, B.4
  • 219
    • 36549044418 scopus 로고    scopus 로고
    • TGFβ1 expressed in the TGFβ3 locus partially rescues the cleft palate phenotype of TGFβ3 null mutants
    • Yang LT, Kaartinen V. 2007. TGFβ1 expressed in the TGFβ3 locus partially rescues the cleft palate phenotype of TGFβ3 null mutants. Dev Biol 312: 384-395.
    • (2007) Dev Biol , vol.312 , pp. 384-395
    • Yang, L.T.1    Kaartinen, V.2
  • 220
    • 25444473619 scopus 로고    scopus 로고
    • Targeted disruption of Smad4 in mouse epidermis results in failure of hair follicle cycling and formation of skin tumors
    • Yang L, Mao C, Teng Y, Li W, Zhang J, Cheng X, Li X, Han X, Xia Z, Deng H, et al. 2005. Targeted disruption of Smad4 in mouse epidermis results in failure of hair follicle cycling and formation of skin tumors. Cancer Res 65: 8671-8678.
    • (2005) Cancer Res , vol.65 , pp. 8671-8678
    • Yang, L.1    Mao, C.2    Teng, Y.3    Li, W.4    Zhang, J.5    Cheng, X.6    Li, X.7    Han, X.8    Xia, Z.9    Deng, H.10
  • 221
    • 64049091922 scopus 로고    scopus 로고
    • Disruption of Smad4 in mouse epidermis leads to depletion of follicle stem cells
    • Yang L, Wang L, Yang X. 2009. Disruption of Smad4 in mouse epidermis leads to depletion of follicle stem cells. Mol Biol Cell 20: 882-890.
    • (2009) Mol Biol Cell , vol.20 , pp. 882-890
    • Yang, L.1    Wang, L.2    Yang, X.3
  • 222
    • 84891712260 scopus 로고    scopus 로고
    • Cessation of epithelial Bmp signaling switches the differentiation of crown epithelia to the root lineage in a b-catenin-dependent manner
    • Yang Z, Hai B, Qin L, Ti X, Shangguan L, Zhao Y, Wiggins L, Liu Y, Feng JQ, Chang JY, et al. 2013. Cessation of epithelial Bmp signaling switches the differentiation of crown epithelia to the root lineage in a b-catenin-dependent manner. Mol Cell Biol 33: 4732-4744.
    • (2013) Mol Cell Biol , vol.33 , pp. 4732-4744
    • Yang, Z.1    Hai, B.2    Qin, L.3    Ti, X.4    Shangguan, L.5    Zhao, Y.6    Wiggins, L.7    Liu, Y.8    Feng, J.Q.9    Chang, J.Y.10
  • 224
    • 54549086654 scopus 로고    scopus 로고
    • The role of twist during palate development
    • Yu W, Kamara H, Svoboda KK. 2008. The role of twist during palate development. Dev Dyn 237: 2716-2725.
    • (2008) Dev Dyn , vol.237 , pp. 2716-2725
    • Yu, W.1    Kamara, H.2    Svoboda, K.K.3
  • 225
    • 84918549050 scopus 로고    scopus 로고
    • The non-canonical BMP and Wnt/b-catenin signaling pathways orchestrate early tooth development
    • Yuan G, Yang G, Zheng Y, Zhu X, Chen Z, Zhang Z, Chen Y. 2015. The non-canonical BMP and Wnt/b-catenin signaling pathways orchestrate early tooth development. Development 142: 128-139.
    • (2015) Development , vol.142 , pp. 128-139
    • Yuan, G.1    Yang, G.2    Zheng, Y.3    Zhu, X.4    Chen, Z.5    Zhang, Z.6    Chen, Y.7
  • 227
    • 0038717407 scopus 로고    scopus 로고
    • BMP-7 counteracts TGF-β1- induced epithelial-to-mesenchymal transition and reverses chronic renal injury
    • Zeisberg M, Hanai J, Sugimoto H, Mammoto T, Charytan D, Strutz F, Kalluri R. 2003. BMP-7 counteracts TGF-β1- induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat Med 9: 964-968.
    • (2003) Nat Med , vol.9 , pp. 964-968
    • Zeisberg, M.1    Hanai, J.2    Sugimoto, H.3    Mammoto, T.4    Charytan, D.5    Strutz, F.6    Kalluri, R.7
  • 228
    • 85011591309 scopus 로고    scopus 로고
    • Non-Smad signaling pathways of the TGF-β family
    • Zhang YE. 2017. Non-Smad signaling pathways of the TGF-β family. Cold Spring Harb Perspect Biol 9: a022129.
    • (2017) Cold Spring Harb Perspect Biol , vol.9
    • Zhang, Y.E.1
  • 229
    • 33846000938 scopus 로고    scopus 로고
    • Bone morphogenetic protein signaling inhibits hair follicle anagen induction by restricting epithelial stem/progenitor cell activation and expansion
    • Zhang J, He XC, Tong WG, Johnson T, Wiedemann LM, Mishina Y, Feng JQ, Li L. 2006. Bone morphogenetic protein signaling inhibits hair follicle anagen induction by restricting epithelial stem/progenitor cell activation and expansion. Stem Cells 24: 2826-2839.
    • (2006) Stem Cells , vol.24 , pp. 2826-2839
    • Zhang, J.1    He, X.C.2    Tong, W.G.3    Johnson, T.4    Wiedemann, L.M.5    Mishina, Y.6    Feng, J.Q.7    Li, L.8
  • 231
    • 69249202346 scopus 로고    scopus 로고
    • Distinct self-renewal and differentiation phases in the niche of infrequently dividing hair follicle stem cells
    • Zhang YV, Cheong J, Ciapurin N, McDermitt DJ, Tumbar T. 2009. Distinct self-renewal and differentiation phases in the niche of infrequently dividing hair follicle stem cells. Cell Stem Cell 5: 267-278.
    • (2009) Cell Stem Cell , vol.5 , pp. 267-278
    • Zhang, Y.V.1    Cheong, J.2    Ciapurin, N.3    McDermitt, D.J.4    Tumbar, T.5
  • 232
    • 84875382703 scopus 로고    scopus 로고
    • MicroRNA profile analysis on duck feather follicle and skin with high-throughput sequencing technology
    • Zhang L, Nie Q, Su Y, Xie X, Luo W, Jia X, Zhang X. 2013. MicroRNA profile analysis on duck feather follicle and skin with high-throughput sequencing technology. Gene 519: 77-81.
    • (2013) Gene , vol.519 , pp. 77-81
    • Zhang, L.1    Nie, Q.2    Su, Y.3    Xie, X.4    Luo, W.5    Jia, X.6    Zhang, X.7
  • 233
    • 79956072028 scopus 로고    scopus 로고
    • Alk5-mediated transforming growth factor b signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells
    • Zhao H, Li S, Han D, Kaartinen V, Chai Y. 2011. Alk5-mediated transforming growth factor b signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells. Mol Cell Biol 31: 2079-2089.
    • (2011) Mol Cell Biol , vol.31 , pp. 2079-2089
    • Zhao, H.1    Li, S.2    Han, D.3    Kaartinen, V.4    Chai, Y.5
  • 234
    • 0028935955 scopus 로고
    • Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate
    • Zhou P, Byrne C, Jacobs J, Fuchs E. 1995. Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate. Genes Dev 9: 700-713.
    • (1995) Genes Dev , vol.9 , pp. 700-713
    • Zhou, P.1    Byrne, C.2    Jacobs, J.3    Fuchs, E.4
  • 235
    • 84908346597 scopus 로고    scopus 로고
    • BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin
    • Zhu XJ, Liu Y, Dai ZM, Zhang X, Yang X, Li Y, Qiu M, Fu J, Hsu W, Chen Y, et al. 2014. BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin. PLoS Genet 10: e1004687.
    • (2014) Plos Genet , vol.10
    • Zhu, X.J.1    Liu, Y.2    Dai, Z.M.3    Zhang, X.4    Yang, X.5    Li, Y.6    Qiu, M.7    Fu, J.8    Hsu, W.9    Chen, Y.10
  • 236
    • 33744544424 scopus 로고    scopus 로고
    • P38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation
    • Zohn IE, Li Y, Skolnik EY, Anderson KV, Han J, Niswander L. 2006. p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation. Cell 125: 957-969.
    • (2006) Cell , vol.125 , pp. 957-969
    • Zohn, I.E.1    Li, Y.2    Skolnik, E.Y.3    Anderson, K.V.4    Han, J.5    Niswander, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.