The winged-helix transcription factor Foxd3 suppresses interneuron differentiation and promotes neural crest cell fate

Development

Volumn 128, Issue 21, 2001, Pages 4127-4138

  Dottori, M ^a   Gross, M K ^a   Labosky, P ^a   Goulding, M ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

Chick; Foxd3; Mouse; Neural crest specification; Neural tube development; Winged helix genes

Indexed keywords

CAD7 PROTEIN; GENE PRODUCT; HNK1 PROTEIN; RHO FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXD3; TRANSCRIPTION FACTOR PAX3; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ANIMAL CELL; ARTICLE; CELL FATE; CELL MATURATION; CELL MIGRATION; CELL POPULATION; CELL TYPE; CHICKEN; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; GENE FUNCTION; GENE REPRESSION; INTERNEURON; MIGRATION; MOLECULAR GENETICS; MOUSE; MOUSE MUTANT; NERVE CELL DIFFERENTIATION; NEURAL CREST; NEURAL CREST CELL; NEURAL TUBE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; VERTEBRATE;

ANIMALS; ANTIGENS, CD57; AVIAN PROTEINS; BIOLOGICAL MARKERS; CADHERINS; CELL DIFFERENTIATION; CELL MOVEMENT; CHICK EMBRYO; DNA-BINDING PROTEINS; EMBRYONIC INDUCTION; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HELIX-TURN-HELIX MOTIFS; MICE; MICE, MUTANT STRAINS; NEURAL CREST; NEURONS; PAIRED BOX TRANSCRIPTION FACTORS; REPRESSOR PROTEINS; RHOB GTP-BINDING PROTEIN; SPINAL CORD; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

ANIMALIA; GALLUS GALLUS; GASTROPODA; VERTEBRATA;

EID: 0035164747     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. The neural crest cell lineage problem: Neuropoiesis?
2. Expression of Pax-3 is initiated in the early neural plate by posteriorizing signals produced by the organizer and by posterior non-axial mesoderm
3. Expression of Pax-3 in the lateral neural plate is dependent on a Wnt-mediated signal from the posterior non-axial mesoderm
4. PO is an early marker of the Schwann cell lineage in chickens
5. Analysis of the early stages of trunk neural crest migration in avian embryos using monoclonal antibody HNK-1
6. + interneurons that require Pax6 for their development
7. Splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3
8. Early stages of motor neuron differentiation revealed by expression of homeobox gene Islet-1
9. Brn-3.0 expression identifies early post-mitotic CNS neurons and sensory neural precursors
10. Aberrant cell growth induced by avian winged helix proteins
11. Signals from the notochord regulate the region specific expression of two Pax genes in the developing spinal cord
12. Timing and pattern of cell fate restrictions in the neural crest lineage
13. Insertional mutation of the mouse Msx1 homoeobox gene by a nlacZ reporter gene
14. Genesis, a winged helix transcriptional repressor, has embryonic expression limited to the neural crest, and stimulates proliferation in vitro in a neural development model
15. Embryonic RNA expression patterns of the c-kit receptor and its cognate ligand suggest multiple functional roles in mouse development
16. P. Pax3: A paired domain gene as a regulator in PNS myelination
17. The winged-helix transcription factor Foxd3 is important for establishing the neural crest lineage and repressing melanogenesis in avian embryos
18. Neural crest induction in Xenopus: Evidence for a two-signal model
19. Molecular mechanisms of neural crest formation
20. Snail-related transcriptional repressors are required in Xenopus for both the induction of the neural crest and its subsequent migration
21. The winged helix transcription factor Hfh2 is expressed in neural crest and spinal cord during mouse development
22. The Neural Crest, of Developmental and Cell Biology Series
23. The specification of dorsal cell fates in the vertebrate central nervous system
24. Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm
25. A role for the roof plate and its resident TGFbeta-related proteins in neuronal patterning in the dorsal spinal cord
26. A role for rhoB in the delamination of neural crest cells from the dorsal neural tube
27. Pax3 and Pax7 are expressed in commissural neurons and restrict ventral neuronal identity in the spinal cord
28. Neural crest specification regulated by the helix-loop-helix repressor Id2
29. Role of Mitf in differentiation and transdifferentiation of chicken pigmented epithelial cell
30. Evx1 is a postmitotic determinant of v0 interneuron identity in the spinal cord
31. Defects in sensory and autonomic ganglia and absence of locus coeruleus in mice deficient for the homeobox gene Phox2a
32. Comparison of three nonviral transfection methods for foreign gene expression in early chicken embryos in ovo
33. Neural crest emigration from the neural tube depends on regulated cadherin expression
34. Xenopus Zic family and its role in neural and neural crest development
35. Control of cell behaviour during development by Slug, a zinc finger gene
36. The delayed entry of thoracic neural crest cells into the dorsolateral path is a consequence of the late emigration of melanogenic neural crest cells from the neural tube
37. Regulation of the onset of neural crest migration by coordinated activity of BMP4 and noggin in the dorsal neural tube
38. Effects of Shh and Noggin on neural crest formation demonstrate that BMP is required in the neural tube but not ectoderm
39. A vital dye analysis of the timing and pathways of avian trunk neural crest cell migration
40. Pathways of trunk neural crest migration in the mouse embryo as revealed by vital dye labelling
41. Analysis of neural crest migration in Splotch mice using a neural crest-specific lacZ reporter
42. A mouse embryonic stem cell line showing pluripotency of differentiation in early embryos and ubiquitous beta-galactosidase expression
43. Whole-mount In Situ Hybridization of Vertebrate Embryos
44. The winged helix transcription factor CWH-3 is expressed in developing neural crest cells
45. Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2
46. LH-2: A LIM/homeodomain gene expressed in developing lymphocytes and neural cells
47. Schwann cell differentiation
48. The transcription factors SCIP and Krox-20 mark distinct stages and cell fates in Schwann cell differentiation