p38 and a p38-Interacting Protein Are Critical for Downregulation of E-Cadherin during Mouse Gastrulation

Cell

Volumn 125, Issue 5, 2006, Pages 957-969

  Zohn, Irene E ^a   Li, Yingqiu ^c   Skolnik, Edward Y ^d   Anderson, Kathryn V ^b   Han, Jiahuai ^c   Niswander, Lee ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE P38; TRANSCRIPTION FACTOR SNAIL; UVOMORULIN;

ALLELE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; GASTRULATION; HUMAN; HUMAN CELL; IN VIVO STUDY; MESODERM; MOUSE; MUTAGENESIS; NEURAL TUBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; TRANSCRIPTION REGULATION;

GASTROPODA; VERTEBRATA;

EID: 33744544424     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2006.03.048     Document Type: Article

References (42)

1. Adams R.H., Porras A., Alonso G., Jones M., Vintersten K., Panelli S., Valladares A., Perez L., Klein R., and Nebreda A.R. Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development. Mol. Cell 6 (2000) 109-116
2. Barnes J.D., Crosby J.L., Jones C.M., Wright C.V., and Hogan B.L. Embryonic expression of Lim-1, the mouse homolog of Xenopus Xlim-1, suggests a role in lateral mesoderm differentiation and neurogenesis. Dev. Biol. 161 (1994) 168-178
3. Barrallo-Gimeno A., and Nieto M.A. The Snail genes as inducers of cell movement and survival: implications in development and cancer. Development 132 (2005) 3151-3161
4. Batlle E., Sancho E., Franci C., Dominguez D., Monfar M., Baulida J., and Garcia De Herreros A. The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat. Cell Biol. 2 (2000) 84-89
5. Bottcher R.T., and Niehrs C. Fibroblast growth factor signaling during early vertebrate development. Endocr. Rev. 26 (2005) 63-77
6. Buday L., Wunderlich L., and Tamas P. The Nck family of adapter proteins: regulators of actin cytoskeleton. Cell. Signal. 14 (2002) 723-731
7. Burdsal C.A., Damsky C.H., and Pedersen R.A. The role of E-cadherin and integrins in mesoderm differentiation and migration at the mammalian primitive streak. Development 118 (1993) 829-844
8. Cano A., Perez-Moreno M.A., Rodrigo I., Locascio A., Blanco M.J., del Barrio M.G., Portillo F., and Nieto M.A. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat. Cell Biol. 2 (2000) 76-83
9. Carver E.A., Jiang R., Lan Y., Oram K.F., and Gridley T. The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition. Mol. Cell. Biol. 21 (2001) 8184-8188
10. Chang L., and Karin M. Mammalian MAP kinase signalling cascades. Nature 410 (2001) 37-40
11. Ciruna B., and Rossant J. FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak. Dev. Cell 1 (2001) 37-49
12. Copp A.J., Greene N.D., and Murdoch J.N. The genetic basis of mammalian neurulation. Nat. Rev. Genet. 4 (2003) 784-793
13. Cuenda A., Rouse J., Doza Y.N., Meier R., Cohen P., Gallagher T.F., Young P.R., and Lee J.C. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett. 364 (1995) 229-233
14. Deng C.X., Wynshaw-Boris A., Shen M.M., Daugherty C., Ornitz D.M., and Leder P. Murine FGFR-1 is required for early postimplantation growth and axial organization. Genes Dev. 8 (1994) 3045-3057
15. Garcia-Garcia M.J., Eggenschwiler J.T., Caspary T., Alcorn H.L., Wyler M.R., Huangfu D., Rakeman A.S., Lee J.D., Feinberg E.H., Timmer J.R., and Anderson K.V. Analysis of mouse embryonic patterning and morphogenesis by forward genetics. Proc. Natl. Acad. Sci. USA 102 (2005) 5913-5919
16. Ge B., Gram H., Di Padova F., Huang B., New L., Ulevitch R.J., Luo Y., and Han J. MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha. Science 295 (2002) 1291-1294
17. Gomes I., Sharma T.T., Edassery S., Fulton N., Mar B.G., and Westbrook C.A. Novel transcription factors in human CD34 antigen-positive hematopoietic cells. Blood 100 (2002) 107-119
18. Holmes G., and Niswander L. Expression of slit-2 and slit-3 during chick development. Dev. Dyn. 222 (2001) 301-307
19. Kasarskis A., Manova K., and Anderson K.V. A phenotype-based screen for embryonic lethal mutations in the mouse. Proc. Natl. Acad. Sci. USA 95 (1998) 7485-7490
20. Kuan C.Y., Yang D.D., Samanta Roy D.R., Davis R.J., Rakic P., and Flavell R.A. The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development. Neuron 22 (1999) 667-676
21. Kuida K., and Boucher D.M. Functions of MAP kinases: insights from gene-targeting studies. J. Biochem. (Tokyo) 135 (2004) 653-656
22. Liu A., Joyner A.L., and Turnbull D.H. Alteration of limb and brain patterning in early mouse embryos by ultrasound-guided injection of Shh-expressing cells. Mech. Dev. 75 (1998) 107-115
23. Maekawa M., Yamamoto T., Tanoue T., Yuasa Y., Chisaka O., and Nishida E. Requirement of the MAP kinase signaling pathways for mouse preimplantation development. Development 132 (2005) 1773-1783
24. Meyers E.N., Lewandoski M., and Martin G.R. An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination. Nat. Genet. 18 (1998) 136-141
25. Mikkola I., Bruun J.A., Bjorkoy G., Holm T., and Johansen T. Phosphorylation of the transactivation domain of Pax6 by extracellular signal-regulated kinase and p38 mitogen-activated protein kinase. J. Biol. Chem. 274 (1999) 15115-15126
26. Mudgett J.S., Ding J., Guh-Siesel L., Chartrain N.A., Yang L., Gopal S., and Shen M.M. Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis. Proc. Natl. Acad. Sci. USA 97 (2000) 10454-10459
27. Natale D.R., Paliga A.J., Beier F., D'Souza S.J., and Watson A.J. p38 MAPK signaling during murine preimplantation development. Dev. Biol. 268 (2004) 76-88
28. New L., and Han J. The p38 MAP kinase pathway and its biological function. Trends Cardiovasc. Med. 8 (1998) 220-228
29. Paricio N., Feiguin F., Boutros M., Eaton S., and Mlodzik M. The Drosophila STE20-like kinase misshapen is required downstream of the Frizzled receptor in planar polarity signaling. EMBO J. 18 (1999) 4669-4678
30. Sabapathy K., Jochum W., Hochedlinger K., Chang L., Karin M., and Wagner E.F. Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2. Mech. Dev. 89 (1999) 115-124
31. Schmidt U., Fiedler U., Pilarsky C.P., Ehlers W., Fussel S., Haase M., Faller G., Sauter G., and Wirth M.P. Identification of a novel gene on chromosome 13 between BRCA-2 and RB-1. Prostate 47 (2001) 91-101
32. Schmidt U., Fuessel S., Haase M., Kraemer K., Meye A., and Wirth M.P. Quantification of C13orf19/P38IP mRNA expression by quantitative real-time PCR in patients with urological malignancies. Cancer Lett. 225 (2005) 253-260
33. Shook D., and Keller R. Mechanisms, mechanics and function of epithelial-mesenchymal transitions in early development. Mech. Dev. 120 (2003) 1351-1383
34. Stokoe D., Campbell D.G., Nakielny S., Hidaka H., Leevers S.J., Marshall C., and Cohen P. MAPKAP kinase-2; a novel protein kinase activated by mitogen-activated protein kinase. EMBO J. 11 (1992) 3985-3994
35. Su Y.C., Han J., Xu S., Cobb M., and Skolnik E.Y. NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain. EMBO J. 16 (1997) 1279-1290
36. Su Y.C., Treisman J.E., and Skolnik E.Y. The Drosophila Ste20-related kinase misshapen is required for embryonic dorsal closure and acts through a JNK MAPK module on an evolutionarily conserved signaling pathway. Genes Dev. 12 (1998) 2371-2380
37. Sun X., Meyers E.N., Lewandoski M., and Martin G.R. Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo. Genes Dev. 13 (1999) 1834-1846
38. Tam P.P., and Behringer R.R. Mouse gastrulation: the formation of a mammalian body plan. Mech. Dev. 68 (1997) 3-25
39. Timmer J.R., Wang C., and Niswander L. BMP signaling patterns the dorsal and intermediate neural tube via regulation of homeobox and helix-loop-helix transcription factors. Development 129 (2002) 2459-2472
40. Xue Y., Wang X., Li Z., Gotoh N., Chapman D., and Skolnik E.Y. Mesodermal patterning defect in mice lacking the Ste20 NCK interacting kinase (NIK). Development 128 (2001) 1559-1572
41. Yamaguchi T.P., Harpal K., Henkemeyer M., and Rossant J. fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation. Genes Dev. 8 (1994) 3032-3044
42. Zohn I.E., Anderson K.V., and Niswander L. Using genomewide mutagenesis screens to identify the genes required for neural tube closure in the mouse. Birth Defects Res. A Clin. Mol. Teratol. 73 (2005) 583-590