Expression of a dominant-negative type II transforming growth factor β (TGF-β) receptor in the epidermis of transgenic mice blocks TGF-β-mediated growth inhibition

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 6, 1997, Pages 2386-2391

  Wang, Xiao Jing ^a   Greenhalgh, David A ^a,d   Bickenbach, Jackie R ^a   Jiang, Aibo ^a   Bundman, Donnie S ^a   Krieg, Thomas ^b   Derynck, Rik ^c   Roop, Dennis R ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF COLOGNE   (Germany)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

hyperkeratosis; hyperplasia; keratinocytes; serine; threonine kinase

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; EPIDERMIS; GENE EXPRESSION REGULATION; GROWTH INHIBITION; GROWTH RATE; GROWTH REGULATION; HYPERKERATOSIS; KERATINOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS REGULATION; TRANSGENIC MOUSE;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, NEWBORN; CELL DIVISION; CELLS, CULTURED; EPIDERMIS; EPITOPES; FEMALE; GENES, MYC; HUMANS; HYPERTROPHY; KERATINOCYTES; KERATOSIS; MALE; MICE; MICE, INBRED ICR; MICE, INBRED STRAINS; MICE, TRANSGENIC; MITOTIC INDEX; PROTO-ONCOGENE PROTEINS C-MYC; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SKIN; SKIN AGING; SKIN PHYSIOLOGY; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA; MUS MUSCULUS;

EID: 0030953639     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.6.2386     Document Type: Article

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