메뉴 건너뛰기




Volumn 39, Issue 1, 2004, Pages 10-25

Essential roles of BMPR-IA signaling in differentiation and growth of hair follicles and in skin tumorigenesis

Author keywords

BMP receptor; Cre loxP conditional knockout; Hair follicle differentiation; Shh; Stem cell; Tumor; catenin

Indexed keywords

BONE MORPHOGENETIC PROTEIN RECEPTOR; BONE MORPHOGENETIC PROTEIN RECEPTOR 1A; CRE RECOMBINASE; UNCLASSIFIED DRUG;

EID: 2942580631     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.20021     Document Type: Article
Times cited : (70)

References (84)
  • 1
  • 2
    • 0036113510 scopus 로고    scopus 로고
    • WNT signals are required for the initiation of hair follicle development
    • Andl T, Reddy ST, Gaddapara T, Millar SE. 2002. WNT signals are required for the initiation of hair follicle development. Dev Cell 2:643-653.
    • (2002) Dev Cell , vol.2 , pp. 643-653
    • Andl, T.1    Reddy, S.T.2    Gaddapara, T.3    Millar, S.E.4
  • 5
    • 0027478822 scopus 로고
    • Transgenic mice as a model to study the role of TGF-beta-related molecules in hair follicles
    • Blessing M, Nanney LB, King LE, Jones CM, Hogan BL. 1993. Transgenic mice as a model to study the role of TGF-beta-related molecules in hair follicles. Genes Dev 7:204-215.
    • (1993) Genes Dev , vol.7 , pp. 204-215
    • Blessing, M.1    Nanney, L.B.2    King, L.E.3    Jones, C.M.4    Hogan, B.L.5
  • 6
    • 0028990043 scopus 로고
    • Chemical skin carcinogenesis is prevented in mice by the induced expression of a TGF-beta related transgene
    • Blessing M, Nanney LB, King LE, Hogan BL. 1995. Chemical skin carcinogenesis is prevented in mice by the induced expression of a TGF-beta related transgene. Teratog Carcinog Mutagen 15:11-21.
    • (1995) Teratog Carcinog Mutagen , vol.15 , pp. 11-21
    • Blessing, M.1    Nanney, L.B.2    King, L.E.3    Hogan, B.L.4
  • 7
    • 0037241807 scopus 로고    scopus 로고
    • Bone morphogenetic proteins and their antagonists in skin and hair follicle biology
    • Botchkarev VA. 2003. Bone morphogenetic proteins and their antagonists in skin and hair follicle biology. J Invest Dermatol 120:36-47.
    • (2003) J Invest Dermatol , vol.120 , pp. 36-47
    • Botchkarev, V.A.1
  • 10
    • 0029838175 scopus 로고    scopus 로고
    • The product of the mouse nude locus, Whn, regulates the balance between epithelial cell growth and differentiation
    • Brissette JL, Li J, Kamimura J, Lee D, Dotto GP. 1996. The product of the mouse nude locus, Whn, regulates the balance between epithelial cell growth and differentiation. Genes Dev 10:2212-2221.
    • (1996) Genes Dev , vol.10 , pp. 2212-2221
    • Brissette, J.L.1    Li, J.2    Kamimura, J.3    Lee, D.4    Dotto, G.P.5
  • 11
    • 0035479815 scopus 로고    scopus 로고
    • Monstrous attempts at adnexogenesis: Regulating hair follicle progenitors through Sonic hedgehog signaling
    • Callahan CA, Oro AE. 2001. Monstrous attempts at adnexogenesis: regulating hair follicle progenitors through Sonic hedgehog signaling. Curr Opin Genet Dev 11:541-546.
    • (2001) Curr Opin Genet Dev , vol.11 , pp. 541-546
    • Callahan, C.A.1    Oro, A.E.2
  • 12
    • 0032953231 scopus 로고    scopus 로고
    • A common human skin tumour is caused by activating mutations in beta-catenin
    • Chan EF, Gat U, McNiff JM, Fuchs E. 1999. A common human skin tumour is caused by activating mutations in beta-catenin. Nat Genet 21:410-413.
    • (1999) Nat Genet , vol.21 , pp. 410-413
    • Chan, E.F.1    Gat, U.2    McNiff, J.M.3    Fuchs, E.4
  • 14
    • 0025313294 scopus 로고
    • Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis
    • Cotsarelis G, Sun TT, Lavker RM. 1990. Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 61:1329-1337.
    • (1990) Cell , vol.61 , pp. 1329-1337
    • Cotsarelis, G.1    Sun, T.T.2    Lavker, R.M.3
  • 15
    • 0032951368 scopus 로고    scopus 로고
    • Epithelial stem cells in the skin: Definition, markers, localization and functions
    • Cotsarelis G, Kaur P, Dhouailly D, Hengge U, Bickenbach J. 1999. Epithelial stem cells in the skin: definition, markers, localization and functions. Exp Dermatol 8:80-88.
    • (1999) Exp Dermatol , vol.8 , pp. 80-88
    • Cotsarelis, G.1    Kaur, P.2    Dhouailly, D.3    Hengge, U.4    Bickenbach, J.5
  • 16
    • 0031884022 scopus 로고    scopus 로고
    • A new role for Notch and Delta in cell fate decisions: Patterning the feather array
    • Crowe R, Henrique D, Ish-Horowicz D, Niswander L. 1998. A new role for Notch and Delta in cell fate decisions: patterning the feather array. Development 125:767-775.
    • (1998) Development , vol.125 , pp. 767-775
    • Crowe, R.1    Henrique, D.2    Ish-Horowicz, D.3    Niswander, L.4
  • 17
    • 0032718124 scopus 로고    scopus 로고
    • Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation
    • DasGupta R, Fuchs E. 1999. Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation. Development 126:4557-4568.
    • (1999) Development , vol.126 , pp. 4557-4568
    • DasGupta, R.1    Fuchs, E.2
  • 18
    • 0037157837 scopus 로고    scopus 로고
    • A developmental conundrum: A stabilized form of beta-catenin lacking the transcriptional activation domain triggers features of hair cell fate in epidermal cells and epidermal cell fate in hair follicle cells
    • DasGupta R, Rhee H, Fuchs E. 2002. A developmental conundrum: a stabilized form of beta-catenin lacking the transcriptional activation domain triggers features of hair cell fate in epidermal cells and epidermal cell fate in hair follicle cells. J Cell Biol 158:331-344.
    • (2002) J Cell Biol , vol.158 , pp. 331-344
    • DasGupta, R.1    Rhee, H.2    Fuchs, E.3
  • 19
    • 0032442852 scopus 로고    scopus 로고
    • Smads: Transcriptional activators of TGF-beta responses
    • Derynck R, Zhang Y, Feng XH. 1998. Smads: transcriptional activators of TGF-beta responses. Cell 95:737-740.
    • (1998) Cell , vol.95 , pp. 737-740
    • Derynck, R.1    Zhang, Y.2    Feng, X.H.3
  • 20
    • 0032439155 scopus 로고    scopus 로고
    • Regulation of a hair follicle keratin intermediate filament gene promoter
    • Dunn SM, Keough RA, Rogers GE, Powell BC. 1998. Regulation of a hair follicle keratin intermediate filament gene promoter. J Cell Sci 111:3487-3496.
    • (1998) J Cell Sci , vol.111 , pp. 3487-3496
    • Dunn, S.M.1    Keough, R.A.2    Rogers, G.E.3    Powell, B.C.4
  • 22
    • 0032567078 scopus 로고    scopus 로고
    • De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin
    • Gat U, DasGupta R, Degenstein L, Fuchs E. 1998. De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin. Cell 95:605-614.
    • (1998) Cell , vol.95 , pp. 605-614
    • Gat, U.1    DasGupta, R.2    Degenstein, L.3    Fuchs, E.4
  • 23
    • 0026571418 scopus 로고
    • The secret life of the hair follicle
    • Hardy MH. 1992. The secret life of the hair follicle. Trends Genet 8:55-61.
    • (1992) Trends Genet , vol.8 , pp. 55-61
    • Hardy, M.H.1
  • 24
    • 0035945639 scopus 로고    scopus 로고
    • Smads mediate signaling of the TGFbeta superfamily in normal keratinocytes but are lost during skin chemical carcinogenesis
    • He W, Cao T, Smith DA, Myers TE, Wang XJ. 2001. Smads mediate signaling of the TGFbeta superfamily in normal keratinocytes but are lost during skin chemical carcinogenesis. Oncogene 20:471-483.
    • (2001) Oncogene , vol.20 , pp. 471-483
    • He, W.1    Cao, T.2    Smith, D.A.3    Myers, T.E.4    Wang, X.J.5
  • 25
    • 0037013859 scopus 로고    scopus 로고
    • Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues
    • He W, Li AG, Wang D, Han S, Zheng B, Goumans MJ, Ten Dijke P, Wang XJ. 2002. Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues. EMBO J 21:2580-2590.
    • (2002) EMBO J , vol.21 , pp. 2580-2590
    • He, W.1    Li, A.G.2    Wang, D.3    Han, S.4    Zheng, B.5    Goumans, M.J.6    Ten Dijke, P.7    Wang, X.J.8
  • 26
    • 0032775933 scopus 로고    scopus 로고
    • Involvement of a novel Tnf receptor homologue in hair follicle induction
    • Headon DJ, Overbeek PA. 1999. Involvement of a novel Tnf receptor homologue in hair follicle induction. Nat Genet 22:370-374.
    • (1999) Nat Genet , vol.22 , pp. 370-374
    • Headon, D.J.1    Overbeek, P.A.2
  • 28
    • 0030218004 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in development
    • Hogan BL. 1996. Bone morphogenetic proteins in development. Curr Opin Genet Dev 6:432-438.
    • (1996) Curr Opin Genet Dev , vol.6 , pp. 432-438
    • Hogan, B.L.1
  • 30
    • 0035907041 scopus 로고    scopus 로고
    • beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin
    • Huelsken J, Vogel R, Erdmann B, Cotsarelis G, Birchmeier W. 2001. beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell 105:533-545.
    • (2001) Cell , vol.105 , pp. 533-545
    • Huelsken, J.1    Vogel, R.2    Erdmann, B.3    Cotsarelis, G.4    Birchmeier, W.5
  • 31
    • 0027478216 scopus 로고
    • A mouse model of greig cephalopolysyndactyly syndrome: The extra-toesJ mutation contains an intragenic deletion of the Gli3 gene
    • Hui CC, Joyner AL. 1993. A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene. Nat Genet 3:241-246.
    • (1993) Nat Genet , vol.3 , pp. 241-246
    • Hui, C.C.1    Joyner, A.L.2
  • 32
    • 0037456847 scopus 로고    scopus 로고
    • Links between signal transduction, transcription and adhesion in epithelial bud development
    • Jamora C, DasGupta R, Kocieniewski P, Fuchs E. 2003. Links between signal transduction, transcription and adhesion in epithelial bud development. Nature 422:317-322.
    • (2003) Nature , vol.422 , pp. 317-322
    • Jamora, C.1    DasGupta, R.2    Kocieniewski, P.3    Fuchs, E.4
  • 33
    • 0033456175 scopus 로고    scopus 로고
    • Self-organization of periodic patterns by dissociated feather mesenchymal cells and the regulation of size, number and spacing of primordia
    • Jiang TX, Jung HS, Widelitz RB, Chuong CM. 1999. Self-organization of periodic patterns by dissociated feather mesenchymal cells and the regulation of size, number and spacing of primordia. Development 126:4997-5009.
    • (1999) Development , vol.126 , pp. 4997-5009
    • Jiang, T.X.1    Jung, H.S.2    Widelitz, R.B.3    Chuong, C.M.4
  • 35
    • 0032774661 scopus 로고    scopus 로고
    • Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle
    • Karlsson L, Bondjers C, Betsholtz C. 1999. Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle. Development 126:2611-2621.
    • (1999) Development , vol.126 , pp. 2611-2621
    • Karlsson, L.1    Bondjers, C.2    Betsholtz, C.3
  • 39
    • 0242425844 scopus 로고    scopus 로고
    • Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA
    • Kobielak K, Pasolli HA, Alonso L, Polak L, Fuchs E. 2003. Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA. J Cell Biol 163:609-623.
    • (2003) J Cell Biol , vol.163 , pp. 609-623
    • Kobielak, K.1    Pasolli, H.A.2    Alonso, L.3    Polak, L.4    Fuchs, E.5
  • 40
    • 0029741097 scopus 로고    scopus 로고
    • Lef1 expression is activated by BMP-4 and regulates inductive tissue interactions in tooth and hair development
    • Kratochwil K, Dull M, Farinas I, Galceran J, Grosschedl R. 1996. Lef1 expression is activated by BMP-4 and regulates inductive tissue interactions in tooth and hair development. Genes Dev 10:1382-1394.
    • (1996) Genes Dev , vol.10 , pp. 1382-1394
    • Kratochwil, K.1    Dull, M.2    Farinas, I.3    Galceran, J.4    Grosschedl, R.5
  • 41
    • 0034671830 scopus 로고    scopus 로고
    • Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle
    • Kulessa H, Turk G, Hogan BL. 2000. Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle. EMBO J 19:6664-6674.
    • (2000) EMBO J , vol.19 , pp. 6664-6674
    • Kulessa, H.1    Turk, G.2    Hogan, B.L.3
  • 42
    • 0036195189 scopus 로고    scopus 로고
    • Conditional alleles in mice: Practical considerations for tissue-specific knockouts
    • Kwan KM. 2002. Conditional alleles in mice: practical considerations for tissue-specific knockouts. genesis 32:49-62.
    • (2002) Genesis , vol.32 , pp. 49-62
    • Kwan, K.M.1
  • 44
    • 0034610272 scopus 로고    scopus 로고
    • Epidermal stem cells: Properties, markers, and location
    • Lavker RM, Sun TT. 2000. Epidermal stem cells: properties, markers, and location. Proc Natl Acad Sci USA 97:13473-13475.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13473-13475
    • Lavker, R.M.1    Sun, T.T.2
  • 45
    • 0033561156 scopus 로고    scopus 로고
    • Association between mouse nude gene expression and the initiation of epithelial terminal differentiation
    • Lee D, Prowse DM, Brissette JL. 1999. Association between mouse nude gene expression and the initiation of epithelial terminal differentiation. Dev Biol 208:362-374.
    • (1999) Dev Biol , vol.208 , pp. 362-374
    • Lee, D.1    Prowse, D.M.2    Brissette, J.L.3
  • 46
    • 0037379668 scopus 로고    scopus 로고
    • Roles of TGFbeta signaling in epidermal/appendage development
    • Li AG, Koster MI, Wang XJ. 2003a. Roles of TGFbeta signaling in epidermal/appendage development. Cytokine Growth Factor Rev 14:99-111.
    • (2003) Cytokine Growth Factor Rev , vol.14 , pp. 99-111
    • Li, A.G.1    Koster, M.I.2    Wang, X.J.3
  • 48
    • 0022870457 scopus 로고
    • Acidic and basic hair/nail ("hard") keratins: Their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins
    • Lynch MH, O'Guin WM, Hardy C, Mak L, Sun TT. 1986. Acidic and basic hair/nail ("hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins. J Cell Biol 103:2593-2606.
    • (1986) J Cell Biol , vol.103 , pp. 2593-2606
    • Lynch, M.H.1    O'Guin, W.M.2    Hardy, C.3    Mak, L.4    Sun, T.T.5
  • 49
    • 0024761677 scopus 로고
    • Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic development
    • Lyons KM, Pelton RW, Hogan BL. 1989. Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic development. Genes Dev 3:1657-1668.
    • (1989) Genes Dev , vol.3 , pp. 1657-1668
    • Lyons, K.M.1    Pelton, R.W.2    Hogan, B.L.3
  • 50
    • 0024991197 scopus 로고
    • Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2A (BMP-2A)
    • Lyons KM, Pelton RW, Hogan BL. 1990. Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2A (BMP-2A). Development 109:833-844.
    • (1990) Development , vol.109 , pp. 833-844
    • Lyons, K.M.1    Pelton, R.W.2    Hogan, B.L.3
  • 51
    • 0031685620 scopus 로고    scopus 로고
    • TGF-beta signal transduction
    • Massague J. 1998. TGF-beta signal transduction. Annu Rev Biochem 67:753-791.
    • (1998) Annu Rev Biochem , vol.67 , pp. 753-791
    • Massague, J.1
  • 52
    • 0034574298 scopus 로고    scopus 로고
    • How cells read TGF-beta signals
    • Massague J. 2000. How cells read TGF-beta signals. Nat Rev Mol Cell Biol 1:169-178.
    • (2000) Nat Rev Mol Cell Biol , vol.1 , pp. 169-178
    • Massague, J.1
  • 53
    • 0032722830 scopus 로고    scopus 로고
    • Whn and mHa3 are components of the genetic hierarchy controlling hair follicle differentiation
    • Meier N, Dear TN, Boehm T. 1999. Whn and mHa3 are components of the genetic hierarchy controlling hair follicle differentiation. Mech Dev 89:215-221.
    • (1999) Mech Dev , vol.89 , pp. 215-221
    • Meier, N.1    Dear, T.N.2    Boehm, T.3
  • 54
    • 0036178229 scopus 로고    scopus 로고
    • Molecular mechanisms regulating hair follicle development
    • Millar SE. 2002. Molecular mechanisms regulating hair follicle development. J Invest Dermatol 118:216-225.
    • (2002) J Invest Dermatol , vol.118 , pp. 216-225
    • Millar, S.E.1
  • 55
    • 6244256053 scopus 로고
    • Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis
    • Mishina Y, Suzuki A, Ueno N, Behringer RR. 1995. Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis. Genes Dev 9:3027-3037.
    • (1995) Genes Dev , vol.9 , pp. 3027-3037
    • Mishina, Y.1    Suzuki, A.2    Ueno, N.3    Behringer, R.R.4
  • 57
    • 0036023356 scopus 로고    scopus 로고
    • Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours
    • Niemann C, Owens DM, Hulsken J, Birchmeier W, Watt FM. 2002. Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours. Development 129:95-109.
    • (2002) Development , vol.129 , pp. 95-109
    • Niemann, C.1    Owens, D.M.2    Hulsken, J.3    Birchmeier, W.4    Watt, F.M.5
  • 58
    • 0031767259 scopus 로고    scopus 로고
    • BMPs mediate lateral inhibition at successive stages in feather tract development
    • Noramly S, Morgan BA. 1998. BMPs mediate lateral inhibition at successive stages in feather tract development. Development 125:3775-3787.
    • (1998) Development , vol.125 , pp. 3775-3787
    • Noramly, S.1    Morgan, B.A.2
  • 59
    • 0026503017 scopus 로고
    • Interaction of trichohyalin with intermediate filaments: Three immunologically defined stages of trichohyalin maturation
    • O'Guin WM, Sun TT, Manabe M. 1992. Interaction of trichohyalin with intermediate filaments: three immunologically defined stages of trichohyalin maturation. J Invest Dermatol 98:24-32.
    • (1992) J Invest Dermatol , vol.98 , pp. 24-32
    • O'Guin, W.M.1    Sun, T.T.2    Manabe, M.3
  • 60
    • 0037444064 scopus 로고    scopus 로고
    • Hair cycle regulation of Hedgehog signal reception
    • Oro AE, Higgins K. 2003. Hair cycle regulation of Hedgehog signal reception. Dev Biol 255:238-248.
    • (2003) Dev Biol , vol.255 , pp. 238-248
    • Oro, A.E.1    Higgins, K.2
  • 61
    • 0035951372 scopus 로고    scopus 로고
    • Morphogenesis and renewal of hair follicles from adult multipotent stem cells
    • Oshima H, Rochat A, Kedzia C, Kobayashi K, Barrandon Y. 2001. Morphogenesis and renewal of hair follicles from adult multipotent stem cells. Cell 104:233-245.
    • (2001) Cell , vol.104 , pp. 233-245
    • Oshima, H.1    Rochat, A.2    Kedzia, C.3    Kobayashi, K.4    Barrandon, Y.5
  • 62
    • 0033549754 scopus 로고    scopus 로고
    • The biology of hair follicles
    • Paus R, Cotsarelis G. 1999. The biology of hair follicles. N Engl J Med 341:491-497.
    • (1999) N Engl J Med , vol.341 , pp. 491-497
    • Paus, R.1    Cotsarelis, G.2
  • 63
    • 0036084790 scopus 로고    scopus 로고
    • Trichofolliculoma of the vulva associated with vulvar intraepithelial neoplasia: Report of three cases and review of the literature
    • Peterdy GA, Huettner PC, Rajaram V, Lind AC. 2002. Trichofolliculoma of the vulva associated with vulvar intraepithelial neoplasia: report of three cases and review of the literature. Int J Gynecol Pathol 21:224-230.
    • (2002) Int J Gynecol Pathol , vol.21 , pp. 224-230
    • Peterdy, G.A.1    Huettner, P.C.2    Rajaram, V.3    Lind, A.C.4
  • 64
    • 0035369302 scopus 로고    scopus 로고
    • More than one way to skin a catenin
    • Polakis P. 2001. More than one way to skin a catenin. Cell 105:563-566.
    • (2001) Cell , vol.105 , pp. 563-566
    • Polakis, P.1
  • 66
    • 0027773169 scopus 로고
    • A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: In situ hybridization using digoxigenin-labelled cRNA probes
    • Schaeren-Wiemers N, Gerfin-Moser A. 1993. A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin-labelled cRNA probes. Histochemistry 100:431-440.
    • (1993) Histochemistry , vol.100 , pp. 431-440
    • Schaeren-Wiemers, N.1    Gerfin-Moser, A.2
  • 67
    • 0035202113 scopus 로고    scopus 로고
    • Expression domains in the skin of genes affected by the nude mutation and identified by gene expression profiling
    • Schlake T, Boehm T. 2001. Expression domains in the skin of genes affected by the nude mutation and identified by gene expression profiling. Mech Dev 109:419-422.
    • (2001) Mech Dev , vol.109 , pp. 419-422
    • Schlake, T.1    Boehm, T.2
  • 68
    • 0034069858 scopus 로고    scopus 로고
    • Forkhead/winged-helix transcription factor Whn regulates hair keratin gene expression: Molecular analysis of the nude skin phenotype
    • Schlake T, Schorpp M, Maul-Pavicic A, Malashenko AM, Boehm T. 2000. Forkhead/winged-helix transcription factor Whn regulates hair keratin gene expression: molecular analysis of the nude skin phenotype. Dev Dyn 217:368-376.
    • (2000) Dev Dyn , vol.217 , pp. 368-376
    • Schlake, T.1    Schorpp, M.2    Maul-Pavicic, A.3    Malashenko, A.M.4    Boehm, T.5
  • 69
    • 0025911039 scopus 로고
    • Hair anatomy for the clinician
    • Sperling LC. 1991. Hair anatomy for the clinician. J Am Acad Dermatol 25:1-17.
    • (1991) J Am Acad Dermatol , vol.25 , pp. 1-17
    • Sperling, L.C.1
  • 72
    • 0035902140 scopus 로고    scopus 로고
    • The Hedgehog and Wnt signalling pathways in cancer
    • Taipale J, Beachy PA. 2001. The Hedgehog and Wnt signalling pathways in cancer. Nature 411:349-354.
    • (2001) Nature , vol.411 , pp. 349-354
    • Taipale, J.1    Beachy, P.A.2
  • 73
    • 0034682742 scopus 로고    scopus 로고
    • Involvement of follicular stem cells in forming not only the follicle but also the epidermis
    • Taylor G, Lehrer MS, Jensen PJ, Sun TT, Lavker RM. 2000. Involvement of follicular stem cells in forming not only the follicle but also the epidermis. Cell 102:451-461.
    • (2000) Cell , vol.102 , pp. 451-461
    • Taylor, G.1    Lehrer, M.S.2    Jensen, P.J.3    Sun, T.T.4    Lavker, R.M.5
  • 74
    • 0027945654 scopus 로고
    • Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice
    • van Genderen C, Okamura RM, Farinas I, Quo RG, Parslow TG, Bruhn L, Grosschedl R. 1994. Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice. Genes Dev 8:2691-2703.
    • (1994) Genes Dev , vol.8 , pp. 2691-2703
    • Van Genderen, C.1    Okamura, R.M.2    Farinas, I.3    Quo, R.G.4    Parslow, T.G.5    Bruhn, L.6    Grosschedl, R.7
  • 76
    • 0035935996 scopus 로고    scopus 로고
    • Overexpression of bone morphogenetic protein-6 (BMP-6) in murine epidermis suppresses skin tumor formation by induction of apoptosis and downregulation of fos/jun family members
    • Wach S, Schirmacher P, Protschka M, Blessing M. 2001. Overexpression of bone morphogenetic protein-6 (BMP-6) in murine epidermis suppresses skin tumor formation by induction of apoptosis and downregulation of fos/jun family members. Oncogene 20:7761-7769.
    • (2001) Oncogene , vol.20 , pp. 7761-7769
    • Wach, S.1    Schirmacher, P.2    Protschka, M.3    Blessing, M.4
  • 77
    • 0030953639 scopus 로고    scopus 로고
    • Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition
    • Wang XJ, Greenhalgh DA, Bickenbach JR, Jiang A, Bundman DS, Krieg T, Derynck R, Roop DR. 1997. Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition. Proc Natl Acad Sci USA 94:2386-2391.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 2386-2391
    • Wang, X.J.1    Greenhalgh, D.A.2    Bickenbach, J.R.3    Jiang, A.4    Bundman, D.S.5    Krieg, T.6    Derynck, R.7    Roop, D.R.8
  • 78
    • 0033587687 scopus 로고    scopus 로고
    • Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis
    • Wang XJ, Liefer KM, Tsai S, O'Malley BW, Roop DR. 1999. Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis. Proc Natl Acad Sci USA 96:8483-8488.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 8483-8488
    • Wang, X.J.1    Liefer, K.M.2    Tsai, S.3    O'Malley, B.W.4    Roop, D.R.5
  • 81
    • 0034162739 scopus 로고    scopus 로고
    • beta-Catenin in epithelial morphogenesis: Conversion of part of avian foot scales into feather buds with a mutated beta-catenin
    • Widelitz RB, Jiang TX, Lu J, Chuong CM. 2000. beta-Catenin in epithelial morphogenesis: conversion of part of avian foot scales into feather buds with a mutated beta-catenin. Dev Biol 219:98-114.
    • (2000) Dev Biol , vol.219 , pp. 98-114
    • Widelitz, R.B.1    Jiang, T.X.2    Lu, J.3    Chuong, C.M.4
  • 82
    • 0032807972 scopus 로고    scopus 로고
    • The role of BMP-2 and BMP-4 in follicle initiation and the murine hair cycle
    • Wilson N, Hynd PI, Powell BC. 1999. The role of BMP-2 and BMP-4 in follicle initiation and the murine hair cycle. Exp Dermatol 8:367-368.
    • (1999) Exp Dermatol , vol.8 , pp. 367-368
    • Wilson, N.1    Hynd, P.I.2    Powell, B.C.3
  • 83
    • 0028935955 scopus 로고
    • Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate
    • Zhou P, Byrne C, Jacobs J, Fuchs E. 1995. Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate. Genes Dev 9:700-713.
    • (1995) Genes Dev , vol.9 , pp. 700-713
    • Zhou, P.1    Byrne, C.2    Jacobs, J.3    Fuchs, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.