메뉴 건너뛰기




Volumn 18, Issue 19, 1999, Pages 5205-5215

Overexpression of activin A in the skin of transgenic mice reveals new activities of activin in epidermal morphogenesis, dermal fibrosis and wound repair

Author keywords

Activin; Epidermis; Granulation tissue; Keratinocyte; Wound

Indexed keywords

ACTIVIN A; FIBRONECTIN; KERATIN; TENASCIN;

EID: 0033214191     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.19.5205     Document Type: Article
Times cited : (194)

References (46)
  • 1
    • 0030060831 scopus 로고    scopus 로고
    • Activation of signalling by the activin receptor complex
    • Attisano, L., Wrana, J.L., Montalvo, E. and Massagué, J. (1996) Activation of signalling by the activin receptor complex. Mol. Cell. Biol., 16, 1066-1073.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1066-1073
    • Attisano, L.1    Wrana, J.L.2    Montalvo, E.3    Massagué, J.4
  • 2
    • 0029834634 scopus 로고    scopus 로고
    • Overexpression of bone morphogenetic protein-6 (BMP-6) in the epidermis of transgenic mice: Inhibition or stimulation of proliferation depending on the pattern of transgene expression and formation of psoriatic lesions
    • Blessing, M., Schirmacher, P. and Kaiser, S. (1996) Overexpression of bone morphogenetic protein-6 (BMP-6) in the epidermis of transgenic mice: Inhibition or stimulation of proliferation depending on the pattern of transgene expression and formation of psoriatic lesions. J. Cell Biol., 135, 227-239.
    • (1996) J. Cell Biol. , vol.135 , pp. 227-239
    • Blessing, M.1    Schirmacher, P.2    Kaiser, S.3
  • 4
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P. and Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 5
    • 0028986244 scopus 로고
    • Concerted action of TGF-β1 and its type II receptor in control of epidermal homeostasis in transgenic mice
    • Cui, W., Fowles, D.J., Cousins, F.M., Duffie, E., Bryson, S., Balmain, A. and Akhurst, R.J. (1995) Concerted action of TGF-β1 and its type II receptor in control of epidermal homeostasis in transgenic mice. Genes Dev., 9, 945-955.
    • (1995) Genes Dev. , vol.9 , pp. 945-955
    • Cui, W.1    Fowles, D.J.2    Cousins, F.M.3    Duffie, E.4    Bryson, S.5    Balmain, A.6    Akhurst, R.J.7
  • 6
    • 0030775569 scopus 로고    scopus 로고
    • Localization and cellular sources of activins in normal and fibrotic rat liver
    • De Bleser, P.J., Niki, T., Xu, G., Rogiers, V. and Geerts, A. (1997) Localization and cellular sources of activins in normal and fibrotic rat liver. Hepatology, 26, 905-912.
    • (1997) Hepatology , vol.26 , pp. 905-912
    • De Bleser, P.J.1    Niki, T.2    Xu, G.3    Rogiers, V.4    Geerts, A.5
  • 9
    • 0032436312 scopus 로고    scopus 로고
    • A longitudinal study of maternal serum inhibin-A, inhibin-B, activin-A, activin-AB, pro-alphaC and follistatin during pregnancy
    • Fowler, P.A., Evans, L.W., Groome, N.P., Templeton, A. and Knight, P.G. (1998) A longitudinal study of maternal serum inhibin-A, inhibin-B, activin-A, activin-AB, pro-alphaC and follistatin during pregnancy. Hum. Reprod., 13, 3530-3536.
    • (1998) Hum. Reprod. , vol.13 , pp. 3530-3536
    • Fowler, P.A.1    Evans, L.W.2    Groome, N.P.3    Templeton, A.4    Knight, P.G.5
  • 10
    • 0029802491 scopus 로고    scopus 로고
    • Altered epidermal cell growth control in vivo by inducible expression of transforming growth factor beta 1 in the skin of transgenic mice
    • Fowlis, D.J., Johnson, S.A., Balmain, A. and Akhurst, R.J. (1996) Altered epidermal cell growth control in vivo by inducible expression of transforming growth factor beta 1 in the skin of transgenic mice. Cell Growth Differ., 7, 679-687.
    • (1996) Cell Growth Differ. , vol.7 , pp. 679-687
    • Fowlis, D.J.1    Johnson, S.A.2    Balmain, A.3    Akhurst, R.J.4
  • 11
    • 0025679060 scopus 로고
    • Epidermal differentiation: The bare essentials
    • Fuchs, E. (1990) Epidermal differentiation: The bare essentials. J. Cell Biol., 111, 2807-2814.
    • (1990) J. Cell Biol. , vol.111 , pp. 2807-2814
    • Fuchs, E.1
  • 14
    • 0342902626 scopus 로고    scopus 로고
    • Strong induction of activin expression after injury suggests an important role of activin in wound repair
    • Hübner, G., Hu, Q., Smola, H. and Werner, S. (1996) Strong induction of activin expression after injury suggests an important role of activin in wound repair. Dev. Biol., 173, 490-498.
    • (1996) Dev. Biol. , vol.173 , pp. 490-498
    • Hübner, G.1    Hu, Q.2    Smola, H.3    Werner, S.4
  • 16
    • 0030033697 scopus 로고    scopus 로고
    • Development and application of a two-site enzyme immunoassay for the determination of 'total' activin-a concentrations in serum and follicular fluid
    • Knight, P.G., Muttukrishna, S. and Groome, N.P. (1996) Development and application of a two-site enzyme immunoassay for the determination of 'total' activin-A concentrations in serum and follicular fluid. J. Endocrinol., 148, 267-279.
    • (1996) J. Endocrinol. , vol.148 , pp. 267-279
    • Knight, P.G.1    Muttukrishna, S.2    Groome, N.P.3
  • 17
    • 0029742706 scopus 로고    scopus 로고
    • Transforming growth factor-β: A general review
    • Lawrence, D.A. (1996) Transforming growth factor-β: a general review. Eur. Cytokine Netw., 7, 363-374.
    • (1996) Eur. Cytokine Netw. , vol.7 , pp. 363-374
    • Lawrence, D.A.1
  • 18
    • 0031239988 scopus 로고    scopus 로고
    • Activin has direct long-range signalling activity and can form a concentration gradient by diffusion
    • McDowell, N., Zorn, A.M., Crease, D.J. and Gurdon, J.B. (1997) Activin has direct long-range signalling activity and can form a concentration gradient by diffusion. Curr. Biol., 7, 671-681.
    • (1997) Curr. Biol. , vol.7 , pp. 671-681
    • McDowell, N.1    Zorn, A.M.2    Crease, D.J.3    Gurdon, J.B.4
  • 19
    • 0025222517 scopus 로고
    • The transforming growth factor-β family
    • Massagué, J. (1990) The transforming growth factor-β family. Annu. Rev. Cell Biochem., 6, 597-641.
    • (1990) Annu. Rev. Cell Biochem. , vol.6 , pp. 597-641
    • Massagué, J.1
  • 20
    • 0027658115 scopus 로고
    • Molecular and functional characterization of activin receptors
    • Mathews, L.S. and Vale, W.W. (1993) Molecular and functional characterization of activin receptors. Receptor, 3, 173-181.
    • (1993) Receptor , vol.3 , pp. 173-181
    • Mathews, L.S.1    Vale, W.W.2
  • 22
    • 0030091573 scopus 로고    scopus 로고
    • Expression of immunoreactive activin A protein in remodeling lesions associated with intestinal pulmonary fibrosis
    • Matsuse, T. et al. (1996) Expression of immunoreactive activin A protein in remodeling lesions associated with intestinal pulmonary fibrosis. Am. J. Pathol., 148, 707-713.
    • (1996) Am. J. Pathol. , vol.148 , pp. 707-713
    • Matsuse, T.1
  • 24
    • 0028918915 scopus 로고
    • Multiple defects and perinatal death in mice deficient in follistatin
    • Matzuk, M.M., Lu, N., Vogel, H., Sellheyer, K., Roop, D.R. and Bradley, A. (1995b) Multiple defects and perinatal death in mice deficient in follistatin. Nature, 374, 360-363.
    • (1995) Nature , vol.374 , pp. 360-363
    • Matzuk, M.M.1    Lu, N.2    Vogel, H.3    Sellheyer, K.4    Roop, D.R.5    Bradley, A.6
  • 25
    • 0025339380 scopus 로고
    • Identification of a major keratinocyte cell envelope protein, loricrin
    • Mehrel, T. et al. (1990) Identification of a major keratinocyte cell envelope protein, loricrin. Cell, 61, 1103-1112.
    • (1990) Cell , vol.61 , pp. 1103-1112
    • Mehrel, T.1
  • 26
  • 27
    • 0029003329 scopus 로고
    • Molecular cloning and functional analysis of a new activin β subunit: A dorsal mesoderm-inducing activity in Xenopus
    • Oda, S., Nishimatsu, S.-I., Murakami, K. and Ueno, N. (1995) Molecular cloning and functional analysis of a new activin β subunit: A dorsal mesoderm-inducing activity in Xenopus. Biochem. Biophys. Res. Commun., 210, 581-588.
    • (1995) Biochem. Biophys. Res. Commun. , vol.210 , pp. 581-588
    • Oda, S.1    Nishimatsu, S.-I.2    Murakami, K.3    Ueno, N.4
  • 28
    • 0031016797 scopus 로고    scopus 로고
    • Transforming growth factor betas and wound healing
    • O'Kane, S. and Ferguson, M.W. (1997) Transforming growth factor betas and wound healing. Int. J. Biochem. Cell Biol., 29, 63-78.
    • (1997) Int. J. Biochem. Cell Biol. , vol.29 , pp. 63-78
    • O'Kane, S.1    Ferguson, M.W.2
  • 29
    • 0030756248 scopus 로고    scopus 로고
    • Stimulation of activin A expression in rat aortic smooth muscle cells by thrombin and angiotensin II correlates with neointimal formation in vivo
    • Pawlowski, J.E., Taylor, D.S., Valentine, M., Hail, M.E., Ferrer, P., Kowala, M.C. and Molloy, C.J. (1997) Stimulation of activin A expression in rat aortic smooth muscle cells by thrombin and angiotensin II correlates with neointimal formation in vivo. J. Clin. Invest., 100, 639-648.
    • (1997) J. Clin. Invest. , vol.100 , pp. 639-648
    • Pawlowski, J.E.1    Taylor, D.S.2    Valentine, M.3    Hail, M.E.4    Ferrer, P.5    Kowala, M.C.6    Molloy, C.J.7
  • 30
    • 0031706004 scopus 로고    scopus 로고
    • Follistatin and activin-A in extra-embryonic coelomic and amniotic fluids and maternal serum in early pregnancy
    • Riley, S.C., Balfour, C., Wathen, N.C., Chard, T., Evans, L.W., Groome, N.P. and Wallace, E.M. (1998) Follistatin and activin-A in extra-embryonic coelomic and amniotic fluids and maternal serum in early pregnancy. Hum. Reprod., 13, 2624-2628.
    • (1998) Hum. Reprod. , vol.13 , pp. 2624-2628
    • Riley, S.C.1    Balfour, C.2    Wathen, N.C.3    Chard, T.4    Evans, L.W.5    Groome, N.P.6    Wallace, E.M.7
  • 32
    • 0022471924 scopus 로고
    • Transforming growth factor type beta: Rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro
    • Roberts, A.B. et al. (1986) Transforming growth factor type beta: Rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc. Natl Acad. Sci. USA, 83, 4167-4171.
    • (1986) Proc. Natl Acad. Sci. USA , vol.83 , pp. 4167-4171
    • Roberts, A.B.1
  • 33
    • 0024402762 scopus 로고
    • Density-dependent modulation of synthesis of keratins 1 and 10 in the human keralinocyte line HACAT and in ras-transfected tumorigenic clones
    • Ryle, C.M., Breitkreutz, D., Stark, H.-J., Leigh, I.M., Steinert, P.M., Roop, D. and Fusenig, N.E. (1989) Density-dependent modulation of synthesis of keratins 1 and 10 in the human keralinocyte line HACAT and in ras-transfected tumorigenic clones. Differentiation, 40, 42-54.
    • (1989) Differentiation , vol.40 , pp. 42-54
    • Ryle, C.M.1    Breitkreutz, D.2    Stark, H.-J.3    Leigh, I.M.4    Steinert, P.M.5    Roop, D.6    Fusenig, N.E.7
  • 34
    • 0023263034 scopus 로고
    • Selective suppression of two postnatally acquired 70 kD and 65 kD keratin proteins during continuous treatment of adult mouse tail epidermis with vitamin A
    • Schweizer, J., Fürstenberger, G. and Winter, H. (1987) Selective suppression of two postnatally acquired 70 kD and 65 kD keratin proteins during continuous treatment of adult mouse tail epidermis with vitamin A. J. Invest. Dermatol., 89, 125-131.
    • (1987) J. Invest. Dermatol. , vol.89 , pp. 125-131
    • Schweizer, J.1    Fürstenberger, G.2    Winter, H.3
  • 39
    • 0345105927 scopus 로고
    • Structure and sequence analysis of the human activin beta-A subunit gene
    • Tanimoto, K., Handa, S.I., Ueno, N., Murakami, K. and Fukamizu, A. (1992) Structure and sequence analysis of the human activin beta-A subunit gene. DNA Seq., 2, 304-308.
    • (1992) DNA Seq. , vol.2 , pp. 304-308
    • Tanimoto, K.1    Handa, S.I.2    Ueno, N.3    Murakami, K.4    Fukamizu, A.5
  • 40
    • 0000775642 scopus 로고
    • The inhibin/activin family of hormones and growth factors
    • Sporn, M.D. and Roberts, A.B. (eds). Springer-Verlag, Berlin, Germany
    • Vale, W., Hsueh, A., Rivier, C. and Yu, J. (1990) The inhibin/activin family of hormones and growth factors. In Sporn, M.D. and Roberts, A.B. (eds), Peptide Growth Factors and their Receptors II. Springer-Verlag, Berlin, Germany, pp. 211-248.
    • (1990) Peptide Growth Factors and Their Receptors II , vol.2 , pp. 211-248
    • Vale, W.1    Hsueh, A.2    Rivier, C.3    Yu, J.4
  • 41
    • 0000425845 scopus 로고
    • Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice
    • Vassar, R., Rosenberg, M., Ross, S., Tyner, A. and Fuchs, E. (1989) Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice. Proc. Natl Acad. Sci. USA, 86, 1563-1567.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 1563-1567
    • Vassar, R.1    Rosenberg, M.2    Ross, S.3    Tyner, A.4    Fuchs, E.5
  • 42
    • 0025965905 scopus 로고
    • Amino acid sequence of mouse tenascin and differential expression of two tenascin isoforms during embryogenesis
    • Weller, A., Beck, S. and Ekblom, P. (1991) Amino acid sequence of mouse tenascin and differential expression of two tenascin isoforms during embryogenesis. J. Cell Biol., 122, 355-362.
    • (1991) J. Cell Biol. , vol.122 , pp. 355-362
    • Weller, A.1    Beck, S.2    Ekblom, P.3
  • 43
    • 0027305161 scopus 로고
    • Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation
    • Werner, S., Weinberg, W., Liao, X., Peters, K.G., Blessing, M., Yuspa, S.H., Weiner, R.I. and Williams, L.T. (1993) Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation. EMBO J., 12, 2635-2643.
    • (1993) EMBO J. , vol.12 , pp. 2635-2643
    • Werner, S.1    Weinberg, W.2    Liao, X.3    Peters, K.G.4    Blessing, M.5    Yuspa, S.H.6    Weiner, R.I.7    Williams, L.T.8
  • 44
    • 0028004471 scopus 로고
    • Induction of keratinocyte growth factor expression is reduced and delayed during wound healing in the genetically diabetic mouse
    • Werner, S., Breeden, M., Hübner, G., Greenhalgh, D.G. and Longaker, M.T. (1994) Induction of keratinocyte growth factor expression is reduced and delayed during wound healing in the genetically diabetic mouse. J. Invest. Dermatol., 103, 469-473.
    • (1994) J. Invest. Dermatol. , vol.103 , pp. 469-473
    • Werner, S.1    Breeden, M.2    Hübner, G.3    Greenhalgh, D.G.4    Longaker, M.T.5
  • 45
    • 0023148368 scopus 로고
    • A molecular analysis of mouse development from 8 to 10 days post coitum detects changes only in embryonic globin expression
    • Wilkinson, D., Bailes, J., Champion, J. and McMahon, A. (1987) A molecular analysis of mouse development from 8 to 10 days post coitum detects changes only in embryonic globin expression. Development, 99, 493-500.
    • (1987) Development , vol.99 , pp. 493-500
    • Wilkinson, D.1    Bailes, J.2    Champion, J.3    McMahon, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.