ERK1/2 pathway mediates epithelial-mesenchymal transition by cross-interacting with TGFβ/Smad and Jagged/Notch signaling pathways in lens epithelial cells

International Journal of Molecular Medicine

Volumn 33, Issue 6, 2014, Pages 1664-1670

  Chen, Xiaoyun ^a   Ye, Shaobi ^a   Xiao, Wei ^a   Wang, Wencong ^a   Luo, Lixia ^a   Liu, Yizhi ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Anterior subcapsular cataract; Epithelial mesenchymal transition; Extracellular signal regulated kinase1 2 pathway; Lens epithelial cells; Notch pathway; Posterior capsule opacification

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; COLLAGEN TYPE 4; FIBRONECTIN; JAGGED1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NOTCH RECEPTOR; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; 1,3 BUTADIENE DERIVATIVE; CALCIUM BINDING PROTEIN; MEMBRANE PROTEIN; NITRILE; SERRATE PROTEINS; SIGNAL PEPTIDE;

ARTICLE; CANCER GROWTH; CATARACT; CONTROLLED STUDY; EMBRYO DEVELOPMENT; ENZYME INACTIVATION; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; HUMAN; HUMAN CELL; LENS EPITHELIUM; METASTASIS; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SUBCAPSULAR CATARACT; VISUAL IMPAIRMENT; DRUG EFFECTS; GENETICS; METABOLISM;

BUTADIENES; CALCIUM-BINDING PROTEINS; EPITHELIAL-MESENCHYMAL TRANSITION; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; NITRILES; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 84899504418     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2014.1723     Document Type: Article

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