Expression of a dominant negative type II TGF-β receptor in mouse skin results in an increase in carcinoma incidence and an acceleration of carcinoma development

Oncogene

Volumn 17, Issue 1, 1998, Pages 25-34

  Amendt, C ^a   Schirmacher, P ^a   Weber, H ^a   Blessing, M ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Carcinogenesis; Growth control; Receptor; Skin; Tgf

Indexed keywords

CARCINOGEN; TRANSFORMING GROWTH FACTOR BETA2; TUMOR PROMOTER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASAL CELL; CANCER INHIBITION; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DOMINANT GENE; EPIDERMIS; GENE OVEREXPRESSION; HOMEOSTASIS; KERATINOCYTE; LYMPH FOLLICLE; MOUSE; MUTATION; NONHUMAN; PAPILLOMA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SKIN CARCINOGENESIS; TRANSGENIC MOUSE; TUMOR PROMOTION;

ANIMALIA; MUS MUSCULUS; SECALE CEREALE;

EID: 0032500010     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202161     Document Type: Article

References (64)

1. Akhurst RJ, Fee F and Balmain A. (1988). Nature, 331, 363-365.
2. Arrick BA, Lopez AR, Elfman F, Ebner R, Damsky CH and Derynck R. (1992). J. Cell. Biol., 8, 715 - 726.
3. Attisano L, Carcamo J, Ventura F, Weis FM, Massague J and Wrana JL. (1993). Cell, 75, 671 - 681.
4. Attisano L, Wrana JL, Lopez-Casillas F and Massague J. (1994). Biochim. Biophys. Acta, 1222, 71 - 80.
5. Bailleul B, Surani MA, White S, Barton SC, Brown K, Blessing M, Jorcano J and Balmain A. (1990). Cell, 62, 697 - 708.
6. Balmain A, Ramsden M, Bowden GT and Smith J. (1984). Nature, 307, 658-660.
7. Blessing M, Nanney LB, King LE, Jones CM and Hogan BL. (1993). Genes Dev., 7, 204 - 215.
8. Bottinger EP, Jakubczak JL, Haines DC, Bagnall K and Wakefield LM. (1997). Cancer Res., 57, 5564-5570.
9. Brand T, MacLellan WR and Schneider MD. (1993). J. Biol, Chem., 268, 11500 - 11503.
10. Brown K, Quintanilla M, Ramsden M, Kerr IB. Young S and Balmain A. (1986). Cell, 46, 447-456.
11. Carcamo J, Zentella A and Massague J. (1995). Mol. Cell. Biol., 15, 1573 - 1581.
12. Casatorres J, Navarro JM, Blessing M and Jorcano JL. (1994). J. Biol. Chem., 269, 20489 - 20496.
13. Cheifetz S, Hernandez H, Laiho M, ten Dijke P, Iwata KK and Massague J. (1990). J. Biol. Chem., 265, 20533 - 20538.
14. Choi Y and Fuchs E. (1990). Cell Regul., 1, 791 - 809.
15. Chomczynski P and Sacchi N. (1987). Anal. Biochem., 162, 156 -159.
16. Church GM and Gilbert W. (1984). Proc. Natl. Acad. Sci. USA, 81, 1991 - 1995.
17. Coffey RJ, Jr, Sipes NJ, Bascom CC, Graves-Deal R, Pennington CY, Weissman BE and Moses HL. (1988). Cancer Res., 48, 1596 1602.
18. Cui W, Fowlis DJ, Bryson S, Duffie E, Ireland H, Balmain A and Akhurst RJ. (1996). Cell, 86, 531 - 542.
19. Cui W, Fowlis DJ, Cousins FM, Duffie E, Bryson S, Balmain A and Akhurst RJ. (1995). Genes Dev., 9, 945 - 955.
20. Cui W, Kemp CJ, Duffie E, Balmain A and Akhurst RJ. (1994). Cancer Res., 54, 5831 - 5836.
21. Derynck R. (1994). Trends Biochem. Sci., 19, 548 553.
22. DiGiovanni J. (1991). Modification of Multistage Skin Carcinogenesis in Mice. Modification of Tumor Development in Rodents. Ito N and Sugano H (eds). Karger: Basel, 33: 192-229.
23. Drozdoff V and Pledger WJ. (1993). J. Cell. Biol., 123, 909 - 919.
24. Ebner R, Chen RH, Shum L, Lawler S, Zioncheck TF, Lee A, Lopez AR and Derynck R. (1993). Science, 260, 1344 - 1348.
25. Escherick JS, DiCunto F, Flanders KC, Missero C and Dotto GP. (1993). Cancer Res., 53, 5517 - 5522.
26. Fafeur V, O'Hara B and Bohlen P. (1993). Mol. Biol. Cell., 4, 135 - 144.
27. Fowlis DJ, Cui W, Johnson SA, Balmain A and Akhurst RJ. (1996). Cell Growth Differ., 7, 679-687.
28. Fürstenberger G, Rogers M, Schnapke R, Bauer G, Hofler P and Marks F. (1989). Int. J. Cancer, 43, 915 - 921.
29. Gitelman SE, Kobrin M, Lee A, Fet V, Lyons K, Hogan BLM and Derynck R. (1997). Calcif. Tissue Int., 60, 283 290.
30. Glick AB, Kulkarni AB, Tennenbaum T, Hennings H, Flanders KC, O'Reilly M, Sporn MB, Karlsson S and Yuspa SH. (1993). Proc. Natl. Acad. USA, 90, 6076-6080.
31. Glick AB, Lee MM, Darwiche N, Kulkarni AB, Karlsson S and Yuspa SH. (1994). Genes Dev., 8, 2429-2440.
32. Haddow S, Fowlis DJ, Parkinson K, Akhurst RJ and Balmain A. (1991). Oncogene, 6, 1465-1470.
33. Heldin CH, Miyazono K and ten Dijke P. (1997). Nature, 390, 465-471.
34. Henis YI, Moustakas A, Lin HY and Lodish HF. (1994). J. Cell. Biol., 126, 139 154.
35. Hennings H, Glick AB, Lowry DT, Krsmanovic LS, Sly LM and Yuspa SH. (1993). Carcinogenesis, 14, 2353 2358.
36. Hogan BLM, Costatini F and Lacy E. (eds). (1986). Manipulating the Mouse Embryo. A Laboratory Manual. Cold Spring Harbor Laboratory Press: Cold Spring Harbor, New York.
37. Jorcano JL, Franz JK and Franke WW. (1984a). Differentiation, 28, 155-163.
38. Jorcano JL, Rieger M, Franz JK, Schiller DL, Moll R and Franke WW. (1984b). J. Mol. Biol., 179, 257-281.
39. Kalkhoven E, Roelen BA, de Winter JP, Mummery CL, van den Eijnden-van Raaij AJ, van der Saag PT and van der Burg B. (1995). Cell Growth Differ., 6, 1151 - 1161.
40. Kimchi A, Wang XF, Weinberg RA, Cheifetz S and Massague J. (1988). Science, 240, 196 199.
41. Kingsley DM. (1994). Genes Dev., 8, 133 146.
42. Kitano Y and Okada N. (1983). Br. J. Dermatol., 108, 555 560.
43. Knaus PI, Lindemann D, DeCoteau JF, Perlman R, Yankelev H, Hille M, Kadin ME and Lodish HF. (1996). Mol. Cell Biol., 16, 3480 3489.
44. Lin HY, Wang XF, Ng-Eaton E, Weinberg RA and Lodish HF. (1992). Cell, 68, 775 - 785.
45. Mansbridge JN and Hanawalt PC. (1988). J. Invest. Dermatol., 90, 336-341.
46. Markowitz S, Wang J, Myeroff L, Parsons R, Sun L, Lutterbaugh J, Fan RS, Zborowska E, Kinzler KW, Vogelstein B, Brattain M and Willson JKV. (1995). Science, 268, 1336 - 1338.
47. Miller SJ, Wei ZG, Wilson C, Dzubow L, Sun TT and Lavker RM. (1993). J. Invest. Dermatol., 101, 591 - 594.
48. Missero C, Ramon y Cajal S and Dotto GP. (1991). Proc. Natl. Acad. Sci. USA, 88, 9613 - 9617.
49. Moll R, Franke WW, Schiller DL, Geiger B and Krepler R. (1982). Cell, 31, 11 - 24.
50. Moustakas A, Lin HY, Henis YI, Plamondon J, O'Connor-McCourt MD and Lodish HF. (1993). J. Biol. Chem., 268, 22215-22218.
51. Oft M, Peli J, Rudaz C, Schwartz H, Beug H and Reichmann F. (1996). Genes Dev., 10, 2462 2477
52. Oshima M, Oshima H and Taketo MM. (1996). Dev. Biol., 179, 297 312.
53. Pelton RW, Saxena B, Jones M, Moses HL and Gold LI, (1991). J. Cell. Biol., 5, 1091-1105.
54. Quintanilla M, Brown K, Ramsden M and Balmain A. (1986). Nature, 322, 78-80.
55. Ramirez A, Bravo A, Jorcano JL and Vidal M. (1994). Differentiation 58, 53-64.
56. Roberts AB and Sporn MB. (1990). The transforming growth factors-β. Handbook of Experimental Pharmacology. Peptide Growth Factors and Their Receptors. Sporn MB and Roberts AB. (eds). Springer-Verlag: Berlin, pp. 419-472.
57. Roberts AB, Sporn MB, Assoian RK, Smith JM, Roche NS, Wakefield LM, Heine UI, Liotta LA, Falanga V, Kehrl JH and et al. (1986). Proc. Natl. Acad. Sci. USA, 83, 4167-4171.
58. Sankar S, Mahooti-Brooks N, Centrella M, McCarthy TL and Madri JA. (1995). J. Biol. Chem., 270, 13567-13572.
59. Sellheyer K, Bickenbach JR, Rothnagel JA, Bundman D, Longley MA, Krieg T, Roche NS, Roberts AB and Roop DR. (1993). Proc. Natl. Acad. Sci. USA, 90, 5237 5241.
60. Torre-Amione G, Beauchamp RD, Koeppen H, Park BH, Schreiber H, Moses HL and Rowley DA. (1990). Proc. Natl. Acad. Sci. USA, 87, 1486-1490.
61. Wang XJ, Greenhalgh DA, Bickenbach JR, Jiang A, Bundman DS, Krieg T, Derynck R and Roop DR. (1997). Proc. Natl. Acad. Sci. USA, 94, 2386-2391.
62. Wrana JL, Attisano L, Carcamo J, Zentella A, Doody J, Laiho M, Wang XF and Massague J. (1992). Cell, 71, 1003-1014.
63. Wrana JL, Attisano L, Wieser R, Ventura F and Massague J. (1994). Nature, 370, 341-347.
64. Zhao Y and Young SL. (1996). J. Biol. Chem., 271, 2369-2372.