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Volumn 23, Issue 1, 2018, Pages

Review: Impact of Helicobacter pylori on Alzheimer's disease: What do we know so far?

Author keywords

Alzheimer's disease; cognitive impairment; dementia; gastric inflammation; Helicobacter pylori; tauopathy

Indexed keywords

ALZHEIMER DISEASE; AUTOPHAGY; BLOOD BRAIN BARRIER; DISEASE ASSOCIATION; DISEASE COURSE; ENGLISH (LANGUAGE); HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; MONOCYTE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; ANIMAL; COMPLICATION; GASTROINTESTINAL TRACT; MICROBIOLOGY; OLFACTORY SYSTEM; PATHOLOGY; PHYSIOLOGY;

EID: 85035219140     PISSN: 10834389     EISSN: 15235378     Source Type: Journal    
DOI: 10.1111/hel.12454     Document Type: Review
Times cited : (106)

References (255)
  • 1
    • 85021862389 scopus 로고    scopus 로고
    • Global prevalence of Helicobacter pylori infection: systematic review and meta-analysis
    • Hooi JKY, Lai WY, Ng WK, et al. Global prevalence of Helicobacter pylori infection: systematic review and meta-analysis. Gastroenterology. 2017;153:420-429.
    • (2017) Gastroenterology , vol.153 , pp. 420-429
    • Hooi, J.K.Y.1    Lai, W.Y.2    Ng, W.K.3
  • 2
    • 84906764012 scopus 로고    scopus 로고
    • Epidemiology of Helicobacter pylori infection
    • Eusebi LH, Zagari RM, Bazzoli F. Epidemiology of Helicobacter pylori infection. Helicobacter. 2014;19(Suppl 1):1-5.
    • (2014) Helicobacter , vol.19 , pp. 1-5
    • Eusebi, L.H.1    Zagari, R.M.2    Bazzoli, F.3
  • 3
    • 3142689955 scopus 로고    scopus 로고
    • Glaucoma: ocular Alzheimer's disease?
    • McKinnon SJ. Glaucoma: ocular Alzheimer's disease? Front Biosci. 2003;8:s1140-s1156.
    • (2003) Front Biosci , vol.8 , pp. s1140-s1156
    • McKinnon, S.J.1
  • 4
    • 84992217923 scopus 로고    scopus 로고
    • Number of people blind or visually impaired by glaucoma worldwide and in world regions 1990-2010: a meta-analysis
    • Bourne RRA, Taylor HR, Flaxman SR, et al. Number of people blind or visually impaired by glaucoma worldwide and in world regions 1990-2010: a meta-analysis. PLoS ONE. 2016;11:e0162229.
    • (2016) PLoS ONE , vol.11
    • Bourne, R.R.A.1    Taylor, H.R.2    Flaxman, S.R.3
  • 6
    • 84975515095 scopus 로고    scopus 로고
    • The prevalence and incidence of dementia due to Alzheimer's disease: a systematic review and meta-analysis
    • Fiest KM, Roberts JI, Maxwell CJ, et al. The prevalence and incidence of dementia due to Alzheimer's disease: a systematic review and meta-analysis. Can J Neurol Sci. 2016;43(Suppl 1):S51-S82.
    • (2016) Can J Neurol Sci , vol.43 , pp. S51-S82
    • Fiest, K.M.1    Roberts, J.I.2    Maxwell, C.J.3
  • 7
    • 0000809672 scopus 로고
    • Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration
    • Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet (London, England). 1984;1:1311-1315.
    • (1984) Lancet (London, England) , vol.1 , pp. 1311-1315
    • Marshall, B.J.1    Warren, J.R.2
  • 8
    • 26944442443 scopus 로고    scopus 로고
    • Nobel prize is awarded to doctors who discovered H. pylori
    • Watts G. Nobel prize is awarded to doctors who discovered H. pylori. BMJ. 2005;331:795.
    • (2005) BMJ , vol.331 , pp. 795
    • Watts, G.1
  • 9
    • 85018477868 scopus 로고    scopus 로고
    • Proteolysis in Helicobacter pylori-induced gastric cancer
    • Posselt G, Crabtree JE, Wessler S. Proteolysis in Helicobacter pylori-induced gastric cancer. Toxins (Basel). 2017;9:134.
    • (2017) Toxins (Basel) , vol.9 , pp. 134
    • Posselt, G.1    Crabtree, J.E.2    Wessler, S.3
  • 10
    • 79957861116 scopus 로고    scopus 로고
    • Redox biology and gastric carcinogenesis: the role of Helicobacter pylori
    • Handa O, Naito Y, Yoshikawa T. Redox biology and gastric carcinogenesis: the role of Helicobacter pylori. Redox Rep. 2011;16:1-7.
    • (2011) Redox Rep , vol.16 , pp. 1-7
    • Handa, O.1    Naito, Y.2    Yoshikawa, T.3
  • 11
    • 33751361302 scopus 로고    scopus 로고
    • Bacteria, inflammation, and colon cancer
    • Yang L, Pei Z. Bacteria, inflammation, and colon cancer. World J Gastroenterol. 2006;12:6741-6746.
    • (2006) World J Gastroenterol , vol.12 , pp. 6741-6746
    • Yang, L.1    Pei, Z.2
  • 12
    • 14544295338 scopus 로고    scopus 로고
    • Microbes, immunoregulation, and the gut
    • Rook GAW, Brunet LR. Microbes, immunoregulation, and the gut. Gut. 2005;54:317-320.
    • (2005) Gut , vol.54 , pp. 317-320
    • Rook, G.A.W.1    Brunet, L.R.2
  • 13
    • 80052365606 scopus 로고    scopus 로고
    • Pathobionts of the gastrointestinal microbiota and inflammatory disease
    • Chow J, Tang H, Mazmanian SK. Pathobionts of the gastrointestinal microbiota and inflammatory disease. Curr Opin Immunol. 2011;23:473-480.
    • (2011) Curr Opin Immunol , vol.23 , pp. 473-480
    • Chow, J.1    Tang, H.2    Mazmanian, S.K.3
  • 15
    • 74549211525 scopus 로고    scopus 로고
    • Enterotoxigenic Bacteroides fragilis (ETBF)-mediated colitis in Min (Apc+/-) mice: a human commensal-based murine model of colon carcinogenesis
    • Housseau F, Sears CL. Enterotoxigenic Bacteroides fragilis (ETBF)-mediated colitis in Min (Apc+/-) mice: a human commensal-based murine model of colon carcinogenesis. Cell Cycle. 2010;9:3-5.
    • (2010) Cell Cycle , vol.9 , pp. 3-5
    • Housseau, F.1    Sears, C.L.2
  • 16
    • 38349050145 scopus 로고    scopus 로고
    • Helicobacter hepaticus promotes azoxymethane-initiated colon tumorigenesis in BALB/c-IL10-deficient mice
    • Nagamine CM, Rogers AB, Fox JG, Schauer DB. Helicobacter hepaticus promotes azoxymethane-initiated colon tumorigenesis in BALB/c-IL10-deficient mice. Int J Cancer. 2008;122:832-838.
    • (2008) Int J Cancer , vol.122 , pp. 832-838
    • Nagamine, C.M.1    Rogers, A.B.2    Fox, J.G.3    Schauer, D.B.4
  • 17
    • 84928173592 scopus 로고    scopus 로고
    • Cholera-toxin suppresses carcinogenesis in a mouse model of inflammation-driven sporadic colon cancer
    • Doulberis M, Angelopoulou K, Kaldrymidou E, et al. Cholera-toxin suppresses carcinogenesis in a mouse model of inflammation-driven sporadic colon cancer. Carcinogenesis. 2015;36:280-290.
    • (2015) Carcinogenesis , vol.36 , pp. 280-290
    • Doulberis, M.1    Angelopoulou, K.2    Kaldrymidou, E.3
  • 18
    • 84883200631 scopus 로고    scopus 로고
    • Pathogenic intestinal bacteria enhance prostate cancer development via systemic activation of immune cells in mice
    • Poutahidis T, Cappelle K, Levkovich T, et al. Pathogenic intestinal bacteria enhance prostate cancer development via systemic activation of immune cells in mice. PLoS ONE. 2013;8:e73933.
    • (2013) PLoS ONE , vol.8
    • Poutahidis, T.1    Cappelle, K.2    Levkovich, T.3
  • 19
    • 44849092687 scopus 로고    scopus 로고
    • Suppression of an already established tumor growing through activated mucosal CTLs induced by oral administration of tumor antigen with cholera toxin
    • Wakabayashi A, Nakagawa Y, Shimizu M, Moriya K, Nishiyama Y, Takahashi H. Suppression of an already established tumor growing through activated mucosal CTLs induced by oral administration of tumor antigen with cholera toxin. J Immunol. 2008;180:4000-4010.
    • (2008) J Immunol , vol.180 , pp. 4000-4010
    • Wakabayashi, A.1    Nakagawa, Y.2    Shimizu, M.3    Moriya, K.4    Nishiyama, Y.5    Takahashi, H.6
  • 20
    • 84927797441 scopus 로고    scopus 로고
    • Helicobacter pylori might contribute to nonalcoholic fatty liver disease-related cardiovascular events by releasing prothrombotic and proinflammatory factors
    • Kountouras J, Polyzos SA, Zavos C, et al. Helicobacter pylori might contribute to nonalcoholic fatty liver disease-related cardiovascular events by releasing prothrombotic and proinflammatory factors. Hepatology. 2014;60:1450-1451.
    • (2014) Hepatology , vol.60 , pp. 1450-1451
    • Kountouras, J.1    Polyzos, S.A.2    Zavos, C.3
  • 21
    • 85007189985 scopus 로고    scopus 로고
    • Cardio-cerebrovascular disease and Helicobacter pylori-related metabolic syndrome: We consider eradication therapy as a potential cardio-cerebrovascular prevention strategy
    • Kountouras J, Polyzos SA, Katsinelos P, et al. Cardio-cerebrovascular disease and Helicobacter pylori-related metabolic syndrome: We consider eradication therapy as a potential cardio-cerebrovascular prevention strategy. Int J Cardiol. 2017;229:17-18.
    • (2017) Int J Cardiol , vol.229 , pp. 17-18
    • Kountouras, J.1    Polyzos, S.A.2    Katsinelos, P.3
  • 22
    • 85009212188 scopus 로고    scopus 로고
    • Helicobacter pylori-related metabolic syndrome as predictor of progression to esophageal carcinoma in a subpopulation-based Barrett's esophagus cohort
    • Kountouras J, Polyzos SA, Zeglinas C, et al. Helicobacter pylori-related metabolic syndrome as predictor of progression to esophageal carcinoma in a subpopulation-based Barrett's esophagus cohort. Gastrointest Endosc. 2017;85:462-463.
    • (2017) Gastrointest Endosc , vol.85 , pp. 462-463
    • Kountouras, J.1    Polyzos, S.A.2    Zeglinas, C.3
  • 23
    • 85009809574 scopus 로고    scopus 로고
    • Impact of reactive oxygen species generation on Helicobacter pylori-related extragastric diseases: a hypothesis
    • Kountouras J, Boziki M, Polyzos SA, et al. Impact of reactive oxygen species generation on Helicobacter pylori-related extragastric diseases: a hypothesis. Free Radic Res. 2017;51:73-79.
    • (2017) Free Radic Res , vol.51 , pp. 73-79
    • Kountouras, J.1    Boziki, M.2    Polyzos, S.A.3
  • 24
    • 85012074021 scopus 로고    scopus 로고
    • Helicobacter pylori on portal hypertension-related hepatic encephalopathy
    • Kountouras J, Polyzos SA, Katsinelos P, et al. Helicobacter pylori on portal hypertension-related hepatic encephalopathy. Immunopharmacol Immunotoxicol. 2017;39:105-106.
    • (2017) Immunopharmacol Immunotoxicol , vol.39 , pp. 105-106
    • Kountouras, J.1    Polyzos, S.A.2    Katsinelos, P.3
  • 25
    • 85018554298 scopus 로고    scopus 로고
    • A potential impact of Helicobacter pylori infection on both obstructive sleep apnea and atrial fibrillation-related stroke
    • Kountouras C, Polyzos SA, Stergiopoulos C, et al. A potential impact of Helicobacter pylori infection on both obstructive sleep apnea and atrial fibrillation-related stroke. Sleep Med. 2017;34:256.
    • (2017) Sleep Med , vol.34 , pp. 256
    • Kountouras, C.1    Polyzos, S.A.2    Stergiopoulos, C.3
  • 28
    • 84908671922 scopus 로고    scopus 로고
    • Helicobacter pylori filtrate induces Alzheimer-like tau hyperphosphorylation by activating glycogen synthase kinase-3β
    • Wang X-L, Zeng J, Yang Y, et al. Helicobacter pylori filtrate induces Alzheimer-like tau hyperphosphorylation by activating glycogen synthase kinase-3β. J Alzheimers Dis. 2015;43:153-165.
    • (2015) J Alzheimers Dis , vol.43 , pp. 153-165
    • Wang, X.-L.1    Zeng, J.2    Yang, Y.3
  • 29
    • 84939800911 scopus 로고    scopus 로고
    • The relationship between Helicobacter pylori infection and open-angle glaucoma: a meta-analysis
    • Zeng J, Liu H, Liu X, Ding C. The relationship between Helicobacter pylori infection and open-angle glaucoma: a meta-analysis. Invest Ophthalmol Vis Sci. 2015;56:5238-5245.
    • (2015) Invest Ophthalmol Vis Sci , vol.56 , pp. 5238-5245
    • Zeng, J.1    Liu, H.2    Liu, X.3    Ding, C.4
  • 30
    • 84959502278 scopus 로고    scopus 로고
    • Impact of Helicobacter pylori on multiple sclerosis-related clinically isolated syndrome
    • Deretzi G, Gavalas E, Boziki M, et al. Impact of Helicobacter pylori on multiple sclerosis-related clinically isolated syndrome. Acta Neurol Scand. 2016;133:268-275.
    • (2016) Acta Neurol Scand , vol.133 , pp. 268-275
    • Deretzi, G.1    Gavalas, E.2    Boziki, M.3
  • 31
    • 70349742464 scopus 로고    scopus 로고
    • From the “little brain” gastrointestinal infection to the “big brain” neuroinflammation: a proposed fast axonal transport pathway involved in multiple sclerosis
    • Deretzi G, Kountouras J, Grigoriadis N, et al. From the “little brain” gastrointestinal infection to the “big brain” neuroinflammation: a proposed fast axonal transport pathway involved in multiple sclerosis. Med Hypotheses. 2009;73:781-787.
    • (2009) Med Hypotheses , vol.73 , pp. 781-787
    • Deretzi, G.1    Kountouras, J.2    Grigoriadis, N.3
  • 32
    • 84928403554 scopus 로고    scopus 로고
    • Role of Helicobacter pylori infection on nutrition and metabolism
    • Franceschi F, Annalisa T, Teresa DR, et al. Role of Helicobacter pylori infection on nutrition and metabolism. World J Gastroenterol. 2014;20:12809-12817.
    • (2014) World J Gastroenterol , vol.20 , pp. 12809-12817
    • Franceschi, F.1    Annalisa, T.2    Teresa, D.R.3
  • 33
    • 77957586832 scopus 로고    scopus 로고
    • Five-year survival after Helicobacter pylori eradication in Alzheimer disease patients
    • Kountouras J, Boziki M, Gavalas E, et al. Five-year survival after Helicobacter pylori eradication in Alzheimer disease patients. Cogn Behav Neurol. 2010;23:199-204.
    • (2010) Cogn Behav Neurol , vol.23 , pp. 199-204
    • Kountouras, J.1    Boziki, M.2    Gavalas, E.3
  • 34
    • 67349144455 scopus 로고    scopus 로고
    • Eradication of Helicobacter pylori may be beneficial in the management of Alzheimer's disease
    • Kountouras J, Boziki M, Gavalas E, et al. Eradication of Helicobacter pylori may be beneficial in the management of Alzheimer's disease. J Neurol. 2009;256:758-767.
    • (2009) J Neurol , vol.256 , pp. 758-767
    • Kountouras, J.1    Boziki, M.2    Gavalas, E.3
  • 35
  • 36
    • 84915780084 scopus 로고    scopus 로고
    • Association between Helicobacter pylori burden and Alzheimer's disease
    • Kountouras J, Gavalas E, Polyzos SA, et al. Association between Helicobacter pylori burden and Alzheimer's disease. Eur J Neurol. 2014;21:e100.
    • (2014) Eur J Neurol , vol.21
    • Kountouras, J.1    Gavalas, E.2    Polyzos, S.A.3
  • 37
    • 84928151762 scopus 로고    scopus 로고
    • Helicobacter pylori infection, dementia and primary open-angle glaucoma: are they connected?
    • Tsolaki F, Kountouras J, Topouzis F, Tsolaki M. Helicobacter pylori infection, dementia and primary open-angle glaucoma: are they connected? BMC Ophthalmol. 2015;15:24.
    • (2015) BMC Ophthalmol , vol.15 , pp. 24
    • Tsolaki, F.1    Kountouras, J.2    Topouzis, F.3    Tsolaki, M.4
  • 39
    • 84879077265 scopus 로고    scopus 로고
    • Alzheimer disease in the United States (2010-2050) estimated using the 2010 census
    • Hebert LE, Weuve J, Scherr PA, Evans DA. Alzheimer disease in the United States (2010-2050) estimated using the 2010 census. Neurology. 2013;80:1778-1783.
    • (2013) Neurology , vol.80 , pp. 1778-1783
    • Hebert, L.E.1    Weuve, J.2    Scherr, P.A.3    Evans, D.A.4
  • 41
    • 84954304893 scopus 로고    scopus 로고
    • Trends in dementia incidence: Evolution over a 10-year period in France
    • Grasset L, Brayne C, Joly P, et al. Trends in dementia incidence: Evolution over a 10-year period in France. Alzheimers Dement. 2016;12:272-280.
    • (2016) Alzheimers Dement , vol.12 , pp. 272-280
    • Grasset, L.1    Brayne, C.2    Joly, P.3
  • 43
    • 85012878048 scopus 로고    scopus 로고
    • Trends in prevalence of dementia in French farmers from two epidemiological cohorts
    • Pérès K, Brayne C, Matharan F, et al. Trends in prevalence of dementia in French farmers from two epidemiological cohorts. J Am Geriatr Soc. 2017;65:415-420.
    • (2017) J Am Geriatr Soc , vol.65 , pp. 415-420
    • Pérès, K.1    Brayne, C.2    Matharan, F.3
  • 44
    • 84973345170 scopus 로고    scopus 로고
    • A two decade dementia incidence comparison from the Cognitive Function and Ageing Studies I and II
    • Matthews FE, Stephan BCM, Robinson L, et al. A two decade dementia incidence comparison from the Cognitive Function and Ageing Studies I and II. Nat Commun. 2016;7:11398.
    • (2016) Nat Commun , vol.7 , pp. 11398
    • Matthews, F.E.1    Stephan, B.C.M.2    Robinson, L.3
  • 45
    • 84886240569 scopus 로고    scopus 로고
    • A two-decade comparison of prevalence of dementia in individuals aged 65 years and older from three geographical areas of England: results of the Cognitive Function and Ageing Study I and II
    • Matthews FE, Arthur A, Barnes LE, et al. A two-decade comparison of prevalence of dementia in individuals aged 65 years and older from three geographical areas of England: results of the Cognitive Function and Ageing Study I and II. Lancet (London, England). 2013;382:1405-1412.
    • (2013) Lancet (London, England) , vol.382 , pp. 1405-1412
    • Matthews, F.E.1    Arthur, A.2    Barnes, L.E.3
  • 47
  • 48
    • 84857672339 scopus 로고    scopus 로고
    • Association between Helicobacter pylori infection and Alzheimer's disease in Japan
    • Kountouras J, Zavos C, Boziki M, Gavalas E, Kyriakou P, Deretzi G. Association between Helicobacter pylori infection and Alzheimer's disease in Japan. J Neurol. 2011;258:2086.
    • (2011) J Neurol , vol.258 , pp. 2086
    • Kountouras, J.1    Zavos, C.2    Boziki, M.3    Gavalas, E.4    Kyriakou, P.5    Deretzi, G.6
  • 49
    • 84855192546 scopus 로고    scopus 로고
    • Hpn protein as a mediator between Helicobacter pylori infection and Alzheimer's disease in sub-populations worldwide
    • Zavos C, Kountouras J, Deretzi G, et al. Hpn protein as a mediator between Helicobacter pylori infection and Alzheimer's disease in sub-populations worldwide. Med Hypotheses. 2012;78:349-350.
    • (2012) Med Hypotheses , vol.78 , pp. 349-350
    • Zavos, C.1    Kountouras, J.2    Deretzi, G.3
  • 50
    • 33845301977 scopus 로고    scopus 로고
    • Alzheimer's disease and Helicobacter pylori infection: Defective immune regulation and apoptosis as proposed common links
    • Kountouras J, Gavalas E, Zavos C, et al. Alzheimer's disease and Helicobacter pylori infection: Defective immune regulation and apoptosis as proposed common links. Med Hypotheses. 2007;68:378-388.
    • (2007) Med Hypotheses , vol.68 , pp. 378-388
    • Kountouras, J.1    Gavalas, E.2    Zavos, C.3
  • 51
    • 84946743622 scopus 로고    scopus 로고
    • A study on the association between infectious burden and Alzheimer's disease
    • Bu X-L, Yao X-Q, Jiao S-S, et al. A study on the association between infectious burden and Alzheimer's disease. Eur J Neurol. 2015;22:1519-1525.
    • (2015) Eur J Neurol , vol.22 , pp. 1519-1525
    • Bu, X.-L.1    Yao, X.-Q.2    Jiao, S.-S.3
  • 52
    • 84893934189 scopus 로고    scopus 로고
    • A proposed role of human defensins in Helicobacter pylori-related neurodegenerative disorders
    • Kountouras J, Deretzi G, Gavalas E, et al. A proposed role of human defensins in Helicobacter pylori-related neurodegenerative disorders. Med Hypotheses. 2014;82:368-373.
    • (2014) Med Hypotheses , vol.82 , pp. 368-373
    • Kountouras, J.1    Deretzi, G.2    Gavalas, E.3
  • 53
    • 65649103360 scopus 로고    scopus 로고
    • Increased cerebrospinal fluid Helicobacter pylori antibody in Alzheimer's disease
    • Kountouras J, Boziki M, Gavalas E, et al. Increased cerebrospinal fluid Helicobacter pylori antibody in Alzheimer's disease. Int J Neurosci. 2009;119:765-777.
    • (2009) Int J Neurosci , vol.119 , pp. 765-777
    • Kountouras, J.1    Boziki, M.2    Gavalas, E.3
  • 54
    • 67649962189 scopus 로고    scopus 로고
    • Alzheimer's disease and infection: do infectious agents contribute to progression of Alzheimer's disease?
    • Honjo K, van Reekum R, Verhoeff NPLG. Alzheimer's disease and infection: do infectious agents contribute to progression of Alzheimer's disease? Alzheimers Dement. 2009;5:348-360.
    • (2009) Alzheimers Dement , vol.5 , pp. 348-360
    • Honjo, K.1    van Reekum, R.2    Verhoeff, N.P.L.G.3
  • 55
    • 84964607474 scopus 로고    scopus 로고
    • Predicting the progression of Alzheimer's disease dementia: A multidomain health policy model
    • Green C, Zhang S. Predicting the progression of Alzheimer's disease dementia: A multidomain health policy model. Alzheimers Dement. 2016;12:776-785.
    • (2016) Alzheimers Dement , vol.12 , pp. 776-785
    • Green, C.1    Zhang, S.2
  • 56
    • 80054892940 scopus 로고    scopus 로고
    • Distinguishing Alzheimer's disease from other major forms of dementia
    • Karantzoulis S, Galvin JE. Distinguishing Alzheimer's disease from other major forms of dementia. Expert Rev Neurother. 2011;11:1579-1591.
    • (2011) Expert Rev Neurother , vol.11 , pp. 1579-1591
    • Karantzoulis, S.1    Galvin, J.E.2
  • 57
    • 0035849151 scopus 로고    scopus 로고
    • A reevaluation of the duration of survival after the onset of dementia
    • Wolfson C, Wolfson DB, Asgharian M, et al. A reevaluation of the duration of survival after the onset of dementia. N Engl J Med. 2001;344:1111-1116.
    • (2001) N Engl J Med , vol.344 , pp. 1111-1116
    • Wolfson, C.1    Wolfson, D.B.2    Asgharian, M.3
  • 58
    • 67651046949 scopus 로고    scopus 로고
    • Dysphagia in patients with dementia: Alzheimer versus vascular
    • Suh MK, Kim H, Na DL. Dysphagia in patients with dementia: Alzheimer versus vascular. Alzheimer Dis Assoc Disord. 2009;23:178-184.
    • (2009) Alzheimer Dis Assoc Disord , vol.23 , pp. 178-184
    • Suh, M.K.1    Kim, H.2    Na, D.L.3
  • 59
    • 84861188157 scopus 로고    scopus 로고
    • A potential impact of chronic Helicobacter pylori infection on Alzheimer's disease pathobiology and course
    • Kountouras J, Boziki M, Zavos C, et al. A potential impact of chronic Helicobacter pylori infection on Alzheimer's disease pathobiology and course. Neurobiol Aging. 2012;33:e3-e4.
    • (2012) Neurobiol Aging , vol.33 , pp. e3-e4
    • Kountouras, J.1    Boziki, M.2    Zavos, C.3
  • 60
    • 85015976566 scopus 로고    scopus 로고
    • Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in Alzheimer's disease and Parkinson's disease
    • Ganguly G, Chakrabarti S, Chatterjee U, Saso L. Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in Alzheimer's disease and Parkinson's disease. Drug Des Devel Ther. 2017;11:797-810.
    • (2017) Drug Des Devel Ther , vol.11 , pp. 797-810
    • Ganguly, G.1    Chakrabarti, S.2    Chatterjee, U.3    Saso, L.4
  • 61
    • 39149122810 scopus 로고    scopus 로고
    • Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease
    • Reddy PH, Beal MF. Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease. Trends Mol Med. 2008;14:45-53.
    • (2008) Trends Mol Med , vol.14 , pp. 45-53
    • Reddy, P.H.1    Beal, M.F.2
  • 62
    • 85019566836 scopus 로고    scopus 로고
    • Amyloid is essential but insufficient for Alzheimer causation: addition of subcellular cofactors is required for dementia
    • [Epub ahead of print]
    • Fessel J. Amyloid is essential but insufficient for Alzheimer causation: addition of subcellular cofactors is required for dementia. Int J Geriatr Psychiatry. 2017; https://doi.org/10.1002/gps.4730 [Epub ahead of print].
    • (2017) Int J Geriatr Psychiatry
    • Fessel, J.1
  • 64
    • 85028985879 scopus 로고    scopus 로고
    • Impact of cytokines and chemokines on Alzheimer's disease neuropathological hallmarks
    • Domingues C, da Cruz E Silva OAB, Henriques AG. Impact of cytokines and chemokines on Alzheimer's disease neuropathological hallmarks. Curr Alzheimer Res. 2017;14:870-882.
    • (2017) Curr Alzheimer Res , vol.14 , pp. 870-882
    • Domingues, C.1    da Cruz E Silva, O.A.B.2    Henriques, A.G.3
  • 65
    • 85014151323 scopus 로고    scopus 로고
    • T lymphocytes and inflammatory mediators in the interplay between brain and blood in Alzheimer's disease: potential pools of new biomarkers
    • Mietelska-Porowska A, Wojda U. T lymphocytes and inflammatory mediators in the interplay between brain and blood in Alzheimer's disease: potential pools of new biomarkers. J Immunol Res. 2017;2017:4626540.
    • (2017) J Immunol Res , vol.2017 , pp. 4626540
    • Mietelska-Porowska, A.1    Wojda, U.2
  • 67
    • 29144508651 scopus 로고    scopus 로고
    • Identification and structural characterisation of carboxy-terminal polypeptides and antibody epitopes of Alzheimer's amyloid precursor protein using high-resolution mass spectrometry
    • Tian X, Cecal R, McLaurin J, et al. Identification and structural characterisation of carboxy-terminal polypeptides and antibody epitopes of Alzheimer's amyloid precursor protein using high-resolution mass spectrometry. Eur J Mass Spectrom (Chichester, Eng). 2005;11:547-556.
    • (2005) Eur J Mass Spectrom (Chichester, Eng) , vol.11 , pp. 547-556
    • Tian, X.1    Cecal, R.2    McLaurin, J.3
  • 68
    • 28844456475 scopus 로고    scopus 로고
    • The development of anti-amyloid therapy for Alzheimer's disease : from secretase modulators to polymerisation inhibitors
    • Aisen PS. The development of anti-amyloid therapy for Alzheimer's disease : from secretase modulators to polymerisation inhibitors. CNS Drugs. 2005;19:989-996.
    • (2005) CNS Drugs , vol.19 , pp. 989-996
    • Aisen, P.S.1
  • 69
    • 0037287331 scopus 로고    scopus 로고
    • Role of the immune system in the pathogenesis, prevention and treatment of Alzheimer's disease
    • Blasko I, Grubeck-Loebenstein B. Role of the immune system in the pathogenesis, prevention and treatment of Alzheimer's disease. Drugs Aging. 2003;20:101-113.
    • (2003) Drugs Aging , vol.20 , pp. 101-113
    • Blasko, I.1    Grubeck-Loebenstein, B.2
  • 70
    • 27144511230 scopus 로고    scopus 로고
    • Beta-amyloid immunotherapy prevents synaptic degeneration in a mouse model of Alzheimer's disease
    • Buttini M, Masliah E, Barbour R, et al. Beta-amyloid immunotherapy prevents synaptic degeneration in a mouse model of Alzheimer's disease. J Neurosci. 2005;25:9096-9101.
    • (2005) J Neurosci , vol.25 , pp. 9096-9101
    • Buttini, M.1    Masliah, E.2    Barbour, R.3
  • 71
    • 0031012176 scopus 로고    scopus 로고
    • Neuroautoimmunity: pathogenic implications for Alzheimer's disease
    • Singh VK. Neuroautoimmunity: pathogenic implications for Alzheimer's disease. Gerontology. 1997;43:79-94.
    • (1997) Gerontology , vol.43 , pp. 79-94
    • Singh, V.K.1
  • 72
    • 0141761461 scopus 로고    scopus 로고
    • Role of cytokines in neurological disorders
    • Aarli JA. Role of cytokines in neurological disorders. Curr Med Chem. 2003;10:1931-1937.
    • (2003) Curr Med Chem , vol.10 , pp. 1931-1937
    • Aarli, J.A.1
  • 73
    • 85015712780 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines in Alzheimer's disease
    • Stamouli EC, Politis AM. Pro-inflammatory cytokines in Alzheimer's disease. Psychiatriki. 2016;27:264-275.
    • (2016) Psychiatriki , vol.27 , pp. 264-275
    • Stamouli, E.C.1    Politis, A.M.2
  • 74
    • 33645312379 scopus 로고    scopus 로고
    • Circuitry of nuclear factor kappaB signaling
    • Hoffmann A, Baltimore D. Circuitry of nuclear factor kappaB signaling. Immunol Rev. 2006;210:171-186.
    • (2006) Immunol Rev , vol.210 , pp. 171-186
    • Hoffmann, A.1    Baltimore, D.2
  • 75
    • 84934278495 scopus 로고    scopus 로고
    • Cu(II) enhances the effect of Alzheimer's amyloid-β peptide on microglial activation
    • Yu F, Gong P, Hu Z, et al. Cu(II) enhances the effect of Alzheimer's amyloid-β peptide on microglial activation. J Neuroinflammation. 2015;12:122.
    • (2015) J Neuroinflammation , vol.12 , pp. 122
    • Yu, F.1    Gong, P.2    Hu, Z.3
  • 76
    • 14844321909 scopus 로고    scopus 로고
    • Manganese potentiates in vitro production of proinflammatory cytokines and nitric oxide by microglia through a nuclear factor kappa B-dependent mechanism
    • Filipov NM, Seegal RF, Lawrence DA. Manganese potentiates in vitro production of proinflammatory cytokines and nitric oxide by microglia through a nuclear factor kappa B-dependent mechanism. Toxicol Sci. 2005;84:139-148.
    • (2005) Toxicol Sci , vol.84 , pp. 139-148
    • Filipov, N.M.1    Seegal, R.F.2    Lawrence, D.A.3
  • 77
    • 27744464859 scopus 로고    scopus 로고
    • The microglial “activation” continuum: from innate to adaptive responses
    • Town T, Nikolic V, Tan J. The microglial “activation” continuum: from innate to adaptive responses. J Neuroinflammation. 2005;2:24.
    • (2005) J Neuroinflammation , vol.2 , pp. 24
    • Town, T.1    Nikolic, V.2    Tan, J.3
  • 78
    • 75849133906 scopus 로고    scopus 로고
    • Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's disease
    • Mori T, Koyama N, Arendash GW, Horikoshi-Sakuraba Y, Tan J, Town T. Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's disease. Glia. 2010;58:300-314
    • (2010) Glia , vol.58 , pp. 300-314
    • Mori, T.1    Koyama, N.2    Arendash, G.W.3    Horikoshi-Sakuraba, Y.4    Tan, J.5    Town, T.6
  • 79
    • 84864089849 scopus 로고    scopus 로고
    • Ketamine inhibits lipopolysaccharide-induced astrocytes activation by suppressing TLR4/NF-κB pathway
    • Zhang Y, Wu Y, Li W, et al. Ketamine inhibits lipopolysaccharide-induced astrocytes activation by suppressing TLR4/NF-κB pathway. Cell Physiol Biochem. 2012;30:609-617.
    • (2012) Cell Physiol Biochem , vol.30 , pp. 609-617
    • Zhang, Y.1    Wu, Y.2    Li, W.3
  • 80
    • 84895422067 scopus 로고    scopus 로고
    • Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis
    • Frakes AE, Ferraiuolo L, Haidet-Phillips AM, et al. Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis. Neuron. 2014;81:1009-1023.
    • (2014) Neuron , vol.81 , pp. 1009-1023
    • Frakes, A.E.1    Ferraiuolo, L.2    Haidet-Phillips, A.M.3
  • 81
    • 84942577777 scopus 로고    scopus 로고
    • NFκB signaling drives pro-granulocytic astroglial responses to neuromyelitis optica patient IgG
    • Walker-Caulfield ME, Guo Y, Johnson RK, et al. NFκB signaling drives pro-granulocytic astroglial responses to neuromyelitis optica patient IgG. J Neuroinflammation. 2015;12:185.
    • (2015) J Neuroinflammation , vol.12 , pp. 185
    • Walker-Caulfield, M.E.1    Guo, Y.2    Johnson, R.K.3
  • 82
    • 84911397353 scopus 로고    scopus 로고
    • Astrocytic metabolic and inflammatory changes as a function of age
    • Jiang T, Cadenas E. Astrocytic metabolic and inflammatory changes as a function of age. Aging Cell. 2014;13:1059-1067.
    • (2014) Aging Cell , vol.13 , pp. 1059-1067
    • Jiang, T.1    Cadenas, E.2
  • 83
    • 0033230204 scopus 로고    scopus 로고
    • Neuronal death in cytokine-activated primary human brain cell culture: role of tumor necrosis factor-alpha
    • Downen M, Amaral TD, Hua LL, Zhao ML, Lee SC. Neuronal death in cytokine-activated primary human brain cell culture: role of tumor necrosis factor-alpha. Glia. 1999;28:114-127.
    • (1999) Glia , vol.28 , pp. 114-127
    • Downen, M.1    Amaral, T.D.2    Hua, L.L.3    Zhao, M.L.4    Lee, S.C.5
  • 84
    • 0034678024 scopus 로고    scopus 로고
    • Beta-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1beta- and tumor necrosis factor-alpha (TNFalpha)-dependent, and involves a TNFalpha receptor-associated factor- and NFkappaB-inducing kinase-dependent signaling mech
    • Akama KT, Van Eldik LJ. Beta-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1beta- and tumor necrosis factor-alpha (TNFalpha)-dependent, and involves a TNFalpha receptor-associated factor- and NFkappaB-inducing kinase-dependent signaling mech. J Biol Chem. 2000;275:7918-7924.
    • (2000) J Biol Chem , vol.275 , pp. 7918-7924
    • Akama, K.T.1    Van Eldik, L.J.2
  • 85
    • 84905001803 scopus 로고    scopus 로고
    • Aggravation of Alzheimer's disease due to the COX-2-mediated reciprocal regulation of IL-1β and Aβ between glial and neuron cells
    • Wang P, Guan P-P, Wang T, Yu X, Guo J-J, Wang Z-Y. Aggravation of Alzheimer's disease due to the COX-2-mediated reciprocal regulation of IL-1β and Aβ between glial and neuron cells. Aging Cell. 2014;13:605-615.
    • (2014) Aging Cell , vol.13 , pp. 605-615
    • Wang, P.1    Guan, P.-P.2    Wang, T.3    Yu, X.4    Guo, J.-J.5    Wang, Z.-Y.6
  • 86
    • 84938747863 scopus 로고    scopus 로고
    • The TNF-α/NF-κB signaling pathway has a key role in methamphetamine-induced blood-brain barrier dysfunction
    • Coelho-Santos V, Leitão RA, Cardoso FL, et al. The TNF-α/NF-κB signaling pathway has a key role in methamphetamine-induced blood-brain barrier dysfunction. J Cereb Blood Flow Metab. 2015;35:1260-1271.
    • (2015) J Cereb Blood Flow Metab , vol.35 , pp. 1260-1271
    • Coelho-Santos, V.1    Leitão, R.A.2    Cardoso, F.L.3
  • 87
    • 84903761512 scopus 로고    scopus 로고
    • Aβ1-42 reduces P-glycoprotein in the blood-brain barrier through RAGE-NF-κB signaling
    • Park R, Kook S-Y, Park J-C, Mook-Jung I. Aβ1-42 reduces P-glycoprotein in the blood-brain barrier through RAGE-NF-κB signaling. Cell Death Dis. 2014;5:e1299.
    • (2014) Cell Death Dis , vol.5
    • Park, R.1    Kook, S.-Y.2    Park, J.-C.3    Mook-Jung, I.4
  • 88
    • 79953025369 scopus 로고    scopus 로고
    • Tetrandrine attenuates spatial memory impairment and hippocampal neuroinflammation via inhibiting NF-κB activation in a rat model of Alzheimer's disease induced by amyloid-β(1-42)
    • He F-Q, Qiu B-Y, Zhang X-H, et al. Tetrandrine attenuates spatial memory impairment and hippocampal neuroinflammation via inhibiting NF-κB activation in a rat model of Alzheimer's disease induced by amyloid-β(1-42). Brain Res. 2011;1384:89-96.
    • (2011) Brain Res , vol.1384 , pp. 89-96
    • He, F.-Q.1    Qiu, B.-Y.2    Zhang, X.-H.3
  • 89
    • 84876536265 scopus 로고    scopus 로고
    • Aspirin-triggered lipoxin A4 stimulates alternative activation of microglia and reduces Alzheimer disease-like pathology in mice
    • Medeiros R, Kitazawa M, Passos GF, et al. Aspirin-triggered lipoxin A4 stimulates alternative activation of microglia and reduces Alzheimer disease-like pathology in mice. Am J Pathol. 2013;182:1780-1789.
    • (2013) Am J Pathol , vol.182 , pp. 1780-1789
    • Medeiros, R.1    Kitazawa, M.2    Passos, G.F.3
  • 90
    • 85017137445 scopus 로고    scopus 로고
    • Artemisinin protects PC12 cells against β-amyloid-induced apoptosis through activation of the ERK1/2 signaling pathway
    • Zeng Z, Xu J, Zheng W. Artemisinin protects PC12 cells against β-amyloid-induced apoptosis through activation of the ERK1/2 signaling pathway. Redox Biol. 2017;12:625-633.
    • (2017) Redox Biol , vol.12 , pp. 625-633
    • Zeng, Z.1    Xu, J.2    Zheng, W.3
  • 91
    • 84892503390 scopus 로고    scopus 로고
    • Astrocytes play a key role in EAE pathophysiology by orchestrating in the CNS the inflammatory response of resident and peripheral immune cells and by suppressing remyelination
    • Brambilla R, Morton PD, Ashbaugh JJ, Karmally S, Lambertsen KL, Bethea JR. Astrocytes play a key role in EAE pathophysiology by orchestrating in the CNS the inflammatory response of resident and peripheral immune cells and by suppressing remyelination. Glia. 2014;62:452-467.
    • (2014) Glia , vol.62 , pp. 452-467
    • Brambilla, R.1    Morton, P.D.2    Ashbaugh, J.J.3    Karmally, S.4    Lambertsen, K.L.5    Bethea, J.R.6
  • 92
    • 0023633015 scopus 로고
    • Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR
    • McGeer PL, Itagaki S, Tago H, McGeer EG. Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR. Neurosci Lett. 1987;79:195-200.
    • (1987) Neurosci Lett , vol.79 , pp. 195-200
    • McGeer, P.L.1    Itagaki, S.2    Tago, H.3    McGeer, E.G.4
  • 93
    • 32944482082 scopus 로고    scopus 로고
    • The role of TNF related apoptosis-inducing ligand in neurodegenerative diseases
    • Huang Y, Erdmann N, Peng H, Zhao Y, Zheng J. The role of TNF related apoptosis-inducing ligand in neurodegenerative diseases. Cell Mol Immunol. 2005;2:113-122.
    • (2005) Cell Mol Immunol , vol.2 , pp. 113-122
    • Huang, Y.1    Erdmann, N.2    Peng, H.3    Zhao, Y.4    Zheng, J.5
  • 94
    • 84935870373 scopus 로고    scopus 로고
    • Ceramides in Alzheimer's disease: key mediators of neuronal apoptosis induced by oxidative stress and Aβ accumulation
    • Jazvinšćak Jembrek M, Hof PR, Šimić G. Ceramides in Alzheimer's disease: key mediators of neuronal apoptosis induced by oxidative stress and Aβ accumulation. Oxid Med Cell Longev. 2015;2015:346783.
    • (2015) Oxid Med Cell Longev , vol.2015 , pp. 346783
    • Jazvinšćak Jembrek, M.1    Hof, P.R.2    Šimić, G.3
  • 95
    • 85018293083 scopus 로고    scopus 로고
    • Treadmill exercise ameliorates symptoms of Alzheimer disease through suppressing microglial activation-induced apoptosis in rats
    • Baek S-S, Kim S-H. Treadmill exercise ameliorates symptoms of Alzheimer disease through suppressing microglial activation-induced apoptosis in rats. J Exerc Rehabil. 2016;12:526-534.
    • (2016) J Exerc Rehabil , vol.12 , pp. 526-534
    • Baek, S.-S.1    Kim, S.-H.2
  • 96
    • 85019031840 scopus 로고    scopus 로고
    • Autophagy activation alleviates amyloid-β-induced oxidative stress, apoptosis and neurotoxicity in human neuroblastoma SH-SY5Y cells
    • Singh AK, Bissoyi A, Kashyap MP, Patra PK, Rizvi SI. Autophagy activation alleviates amyloid-β-induced oxidative stress, apoptosis and neurotoxicity in human neuroblastoma SH-SY5Y cells. Neurotox Res. 2017;32:351-361.
    • (2017) Neurotox Res , vol.32 , pp. 351-361
    • Singh, A.K.1    Bissoyi, A.2    Kashyap, M.P.3    Patra, P.K.4    Rizvi, S.I.5
  • 97
    • 84860216365 scopus 로고    scopus 로고
    • Insights into caspase-mediated apoptotic pathways induced by amyloid-β in cerebral microvascular endothelial cells
    • Fossati S, Ghiso J, Rostagno A. Insights into caspase-mediated apoptotic pathways induced by amyloid-β in cerebral microvascular endothelial cells. Neurodegener Dis. 2012;10:324-328.
    • (2012) Neurodegener Dis , vol.10 , pp. 324-328
    • Fossati, S.1    Ghiso, J.2    Rostagno, A.3
  • 98
    • 68049131389 scopus 로고    scopus 로고
    • Abeta oligomers and fibrillar aggregates induce different apoptotic pathways in LAN5 neuroblastoma cell cultures
    • Picone P, Carrotta R, Montana G, Nobile MR, San Biagio PL, Di Carlo M. Abeta oligomers and fibrillar aggregates induce different apoptotic pathways in LAN5 neuroblastoma cell cultures. Biophys J. 2009;96:4200-4211.
    • (2009) Biophys J , vol.96 , pp. 4200-4211
    • Picone, P.1    Carrotta, R.2    Montana, G.3    Nobile, M.R.4    San Biagio, P.L.5    Di Carlo, M.6
  • 99
    • 70349295278 scopus 로고    scopus 로고
    • Structure-neurotoxicity relationships of amyloid beta-protein oligomers
    • Ono K, Condron MM, Teplow DB. Structure-neurotoxicity relationships of amyloid beta-protein oligomers. Proc Natl Acad Sci U S A. 2009;106:14745-14750.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 14745-14750
    • Ono, K.1    Condron, M.M.2    Teplow, D.B.3
  • 100
    • 75149142245 scopus 로고    scopus 로고
    • Differential activation of mitochondrial apoptotic pathways by vasculotropic amyloid-beta variants in cells composing the cerebral vessel walls
    • Fossati S, Cam J, Meyerson J, et al. Differential activation of mitochondrial apoptotic pathways by vasculotropic amyloid-beta variants in cells composing the cerebral vessel walls. FASEB J. 2010;24:229-241.
    • (2010) FASEB J , vol.24 , pp. 229-241
    • Fossati, S.1    Cam, J.2    Meyerson, J.3
  • 101
    • 85013102318 scopus 로고    scopus 로고
    • Injected Amyloid beta in the olfactory bulb transfers to other brain regions via neural connections in mice
    • [Epub ahead of print]
    • He B, Zheng M, Liu Q, et al. Injected Amyloid beta in the olfactory bulb transfers to other brain regions via neural connections in mice. Mol Neurobiol. 2017. https://doi.org/10.1007/s12035-017-0446-1 [Epub ahead of print].
    • (2017) Mol Neurobiol
    • He, B.1    Zheng, M.2    Liu, Q.3
  • 102
    • 85017538379 scopus 로고    scopus 로고
    • MiR-124-3p attenuates hyperphosphorylation of Tau protein-induced apoptosis via caveolin-1-PI3K/Akt/GSK3β pathway in N2a/APP695swe cells
    • Kang Q, Xiang Y, Li D, et al. MiR-124-3p attenuates hyperphosphorylation of Tau protein-induced apoptosis via caveolin-1-PI3K/Akt/GSK3β pathway in N2a/APP695swe cells. Oncotarget. 2017;8:24314-24326.
    • (2017) Oncotarget , vol.8 , pp. 24314-24326
    • Kang, Q.1    Xiang, Y.2    Li, D.3
  • 103
    • 84946924888 scopus 로고    scopus 로고
    • Antibodies against small heat-shock proteins in Alzheimer's disease as a part of natural human immune repertoire or activation of humoral response?
    • Papuć E, Krupski W, Kurys-Denis E, Rejdak K. Antibodies against small heat-shock proteins in Alzheimer's disease as a part of natural human immune repertoire or activation of humoral response? J Neural Transm. 2016;123:455-461.
    • (2016) J Neural Transm , vol.123 , pp. 455-461
    • Papuć, E.1    Krupski, W.2    Kurys-Denis, E.3    Rejdak, K.4
  • 105
    • 11144275942 scopus 로고    scopus 로고
    • Add Alzheimer's disease to the list of autoimmune diseases
    • D'Andrea MR. Add Alzheimer's disease to the list of autoimmune diseases. Med Hypotheses. 2005;64:458-463.
    • (2005) Med Hypotheses , vol.64 , pp. 458-463
    • D'Andrea, M.R.1
  • 106
    • 84944916968 scopus 로고    scopus 로고
    • Herpes Simplex Virus type-1 infection induces synaptic dysfunction in cultured cortical neurons via GSK-3 activation and intraneuronal amyloid-β protein accumulation
    • Piacentini R, Li Puma DD, Ripoli C, et al. Herpes Simplex Virus type-1 infection induces synaptic dysfunction in cultured cortical neurons via GSK-3 activation and intraneuronal amyloid-β protein accumulation. Sci Rep. 2015;5:15444.
    • (2015) Sci Rep , vol.5 , pp. 15444
    • Piacentini, R.1    Li Puma, D.D.2    Ripoli, C.3
  • 107
    • 84945482050 scopus 로고    scopus 로고
    • Herpes simplex virus type 1 infection in neurons leads to production and nuclear localization of APP intracellular domain (AICD): implications for Alzheimer's disease pathogenesis
    • Civitelli L, Marcocci ME, Celestino I, et al. Herpes simplex virus type 1 infection in neurons leads to production and nuclear localization of APP intracellular domain (AICD): implications for Alzheimer's disease pathogenesis. J Neurovirol. 2015;21:480-490.
    • (2015) J Neurovirol , vol.21 , pp. 480-490
    • Civitelli, L.1    Marcocci, M.E.2    Celestino, I.3
  • 108
    • 84941266767 scopus 로고    scopus 로고
    • Herpes simplex virus type 1 and other pathogens are key causative factors in sporadic Alzheimer's disease
    • Harris SA, Harris EA. Herpes simplex virus type 1 and other pathogens are key causative factors in sporadic Alzheimer's disease. J Alzheimers Dis. 2015;48:319-353.
    • (2015) J Alzheimers Dis , vol.48 , pp. 319-353
    • Harris, S.A.1    Harris, E.A.2
  • 109
    • 58449130099 scopus 로고    scopus 로고
    • Herpes simplex virus type 1 DNA is located within Alzheimer's disease amyloid plaques
    • Wozniak MA, Mee AP, Itzhaki RF. Herpes simplex virus type 1 DNA is located within Alzheimer's disease amyloid plaques. J Pathol. 2009;217:131-138.
    • (2009) J Pathol , vol.217 , pp. 131-138
    • Wozniak, M.A.1    Mee, A.P.2    Itzhaki, R.F.3
  • 110
    • 60349092194 scopus 로고    scopus 로고
    • Alzheimer's disease-specific tau phosphorylation is induced by herpes simplex virus type 1
    • Wozniak MA, Frost AL, Itzhaki RF. Alzheimer's disease-specific tau phosphorylation is induced by herpes simplex virus type 1. J Alzheimers Dis. 2009;16:341-350.
    • (2009) J Alzheimers Dis , vol.16 , pp. 341-350
    • Wozniak, M.A.1    Frost, A.L.2    Itzhaki, R.F.3
  • 111
    • 47849122286 scopus 로고    scopus 로고
    • Neuronal cytoskeletal dynamic modification and neurodegeneration induced by infection with herpes simplex virus type 1
    • Zambrano A, Solis L, Salvadores N, Cortés M, Lerchundi R, Otth C. Neuronal cytoskeletal dynamic modification and neurodegeneration induced by infection with herpes simplex virus type 1. J Alzheimers Dis. 2008;14:259-269.
    • (2008) J Alzheimers Dis , vol.14 , pp. 259-269
    • Zambrano, A.1    Solis, L.2    Salvadores, N.3    Cortés, M.4    Lerchundi, R.5    Otth, C.6
  • 112
    • 77955917442 scopus 로고    scopus 로고
    • Oxidative stress in Alzheimer disease: a possibility for prevention
    • Bonda DJ, Wang X, Perry G, et al. Oxidative stress in Alzheimer disease: a possibility for prevention. Neuropharmacology. 2010;59:290-294.
    • (2010) Neuropharmacology , vol.59 , pp. 290-294
    • Bonda, D.J.1    Wang, X.2    Perry, G.3
  • 113
    • 0031948855 scopus 로고    scopus 로고
    • Evidence of systemic dissemination of Chlamydia pneumoniae via macrophages in the mouse
    • Moazed TC, Kuo CC, Grayston JT, Campbell LA. Evidence of systemic dissemination of Chlamydia pneumoniae via macrophages in the mouse. J Infect Dis. 1998;177:1322-1325.
    • (1998) J Infect Dis , vol.177 , pp. 1322-1325
    • Moazed, T.C.1    Kuo, C.C.2    Grayston, J.T.3    Campbell, L.A.4
  • 114
  • 116
    • 33847009066 scopus 로고    scopus 로고
    • Inflammatory responses following Chlamydia pneumoniae infection of glial cells
    • Boelen E, Steinbusch HWM, Pronk I, et al. Inflammatory responses following Chlamydia pneumoniae infection of glial cells. Eur J Neurosci. 2007;25:753-760.
    • (2007) Eur J Neurosci , vol.25 , pp. 753-760
    • Boelen, E.1    Steinbusch, H.W.M.2    Pronk, I.3
  • 118
    • 32844454831 scopus 로고    scopus 로고
    • Detection of Chlamydia pneumoniae and Helicobacter pylori in atherosclerotic plaques of carotid artery by polymerase chain reaction
    • Kaplan M, Yavuz SS, Cinar B, et al. Detection of Chlamydia pneumoniae and Helicobacter pylori in atherosclerotic plaques of carotid artery by polymerase chain reaction. Int J Infect Dis. 2006;10 2:116-123.
    • (2006) Int J Infect Dis , vol.10 , Issue.2 , pp. 116-123
    • Kaplan, M.1    Yavuz, S.S.2    Cinar, B.3
  • 119
    • 85021109504 scopus 로고    scopus 로고
    • Ultrasound markers of carotid atherosclerosis and cognition: the Northern Manhattan study
    • Gardener H, Caunca MR, Dong C, et al. Ultrasound markers of carotid atherosclerosis and cognition: the Northern Manhattan study. Stroke. 2017;48 7:1855-1861.
    • (2017) Stroke , vol.48 , Issue.7 , pp. 1855-1861
    • Gardener, H.1    Caunca, M.R.2    Dong, C.3
  • 120
    • 78549285952 scopus 로고    scopus 로고
    • Atheromatosis extent in coronary artery disease is not correlated with apolipoprotein-E polymorphism and its plasma levels, but associated with cognitive decline
    • Lima LM, Carvalho MDG, Ferreira CN, et al. Atheromatosis extent in coronary artery disease is not correlated with apolipoprotein-E polymorphism and its plasma levels, but associated with cognitive decline. Curr Alzheimer Res. 2010;7 6:556-563.
    • (2010) Curr Alzheimer Res , vol.7 , Issue.6 , pp. 556-563
    • Lima, L.M.1    Carvalho, M.D.G.2    Ferreira, C.N.3
  • 121
    • 84919664241 scopus 로고    scopus 로고
    • Heart diseases and long-term risk of dementia and Alzheimer's disease: a population-based CAIDE study
    • Rusanen M, Kivipelto M, Levälahti E, et al. Heart diseases and long-term risk of dementia and Alzheimer's disease: a population-based CAIDE study. J Alzheimers Dis. 2014;42 1:183-191.
    • (2014) J Alzheimers Dis , vol.42 , Issue.1 , pp. 183-191
    • Rusanen, M.1    Kivipelto, M.2    Levälahti, E.3
  • 122
    • 79953867838 scopus 로고    scopus 로고
    • Role of Chlamydia pneumoniae, Helicobacter pylori and cytomegalovirus in coronary artery disease
    • Al-Ghamdi A, Jiman-Fatani AA, El-Banna H. Role of Chlamydia pneumoniae, Helicobacter pylori and cytomegalovirus in coronary artery disease. Pak J Pharm Sci. 2011;24 2:95-101.
    • (2011) Pak J Pharm Sci , vol.24 , Issue.2 , pp. 95-101
    • Al-Ghamdi, A.1    Jiman-Fatani, A.A.2    El-Banna, H.3
  • 123
    • 84948071562 scopus 로고    scopus 로고
    • Comparative genomic analysis of human Chlamydia pneumoniae isolates from respiratory, brain and cardiac tissues
    • Roulis E, Bachmann NL, Myers GSA, et al. Comparative genomic analysis of human Chlamydia pneumoniae isolates from respiratory, brain and cardiac tissues. Genomics. 2015;106 6:373-383.
    • (2015) Genomics , vol.106 , Issue.6 , pp. 373-383
    • Roulis, E.1    Bachmann, N.L.2    Myers, G.S.A.3
  • 124
    • 84924869273 scopus 로고    scopus 로고
    • Chlamydia pneumoniae infection of monocytes in vitro stimulates innate and adaptive immune responses relevant to those in Alzheimer's disease
    • Lim C, Hammond CJ, Hingley ST, Balin BJ. Chlamydia pneumoniae infection of monocytes in vitro stimulates innate and adaptive immune responses relevant to those in Alzheimer's disease. J Neuroinflammation. 2014;11 1:217.
    • (2014) J Neuroinflammation , vol.11 , Issue.1 , pp. 217
    • Lim, C.1    Hammond, C.J.2    Hingley, S.T.3    Balin, B.J.4
  • 126
    • 0031857670 scopus 로고    scopus 로고
    • Identification and localization of Chlamydia pneumoniae in the Alzheimer's brain
    • Balin BJ, Gérard HC, Arking EJ, et al. Identification and localization of Chlamydia pneumoniae in the Alzheimer's brain. Med Microbiol Immunol. 1998;187 1:23-42.
    • (1998) Med Microbiol Immunol , vol.187 , Issue.1 , pp. 23-42
    • Balin, B.J.1    Gérard, H.C.2    Arking, E.J.3
  • 128
    • 41949124034 scopus 로고    scopus 로고
    • Inhibition of apoptosis in neuronal cells infected with Chlamydophila (Chlamydia) pneumoniae
    • Appelt DM, Roupas MR, Way DS, et al. Inhibition of apoptosis in neuronal cells infected with Chlamydophila (Chlamydia) pneumoniae. BMC Neurosci. 2008;9:13.
    • (2008) BMC Neurosci , vol.9 , pp. 13
    • Appelt, D.M.1    Roupas, M.R.2    Way, D.S.3
  • 129
    • 1542298233 scopus 로고    scopus 로고
    • Chlamydia pneumoniae induces Alzheimer-like amyloid plaques in brains of BALB/c mice
    • Little CS, Hammond CJ, MacIntyre A, Balin BJ, Appelt DM. Chlamydia pneumoniae induces Alzheimer-like amyloid plaques in brains of BALB/c mice. Neurobiol Aging. 2004;25 4:419-429.
    • (2004) Neurobiol Aging , vol.25 , Issue.4 , pp. 419-429
    • Little, C.S.1    Hammond, C.J.2    MacIntyre, A.3    Balin, B.J.4    Appelt, D.M.5
  • 130
    • 84856390353 scopus 로고    scopus 로고
    • Emerging roles of pathogens in Alzheimer disease
    • Miklossy J. Emerging roles of pathogens in Alzheimer disease. Expert Rev Mol Med. 2011;13:e30.
    • (2011) Expert Rev Mol Med , vol.13
    • Miklossy, J.1
  • 131
    • 0036010892 scopus 로고    scopus 로고
    • Molecular and immunological evidence of oral Treponema in the human brain and their association with Alzheimer's disease
    • Riviere GR, Riviere KH, Smith KS. Molecular and immunological evidence of oral Treponema in the human brain and their association with Alzheimer's disease. Oral Microbiol Immunol. 2002;17:113-118.
    • (2002) Oral Microbiol Immunol , vol.17 , pp. 113-118
    • Riviere, G.R.1    Riviere, K.H.2    Smith, K.S.3
  • 132
    • 12844250088 scopus 로고    scopus 로고
    • Borrelia burgdorferi persists in the brain in chronic lyme neuroborreliosis and may be associated with Alzheimer disease
    • Miklossy J, Khalili K, Gern L, et al. Borrelia burgdorferi persists in the brain in chronic lyme neuroborreliosis and may be associated with Alzheimer disease. J Alzheimers Dis 2004;6:639-649.
    • (2004) J Alzheimers Dis , vol.6 , pp. 639-649
    • Miklossy, J.1    Khalili, K.2    Gern, L.3
  • 133
    • 84885191322 scopus 로고    scopus 로고
    • Respiratory infection promotes T cell infiltration and amyloid-β deposition in APP/PS1 mice
    • McManus RM, Higgins SC, Mills KHG, Lynch MA. Respiratory infection promotes T cell infiltration and amyloid-β deposition in APP/PS1 mice. Neurobiol Aging. 2014;35:109-121.
    • (2014) Neurobiol Aging , vol.35 , pp. 109-121
    • McManus, R.M.1    Higgins, S.C.2    Mills, K.H.G.3    Lynch, M.A.4
  • 134
    • 85015072749 scopus 로고    scopus 로고
    • Novel aspects of defensins' involvement in virus-induced autoimmunity in the central nervous system
    • Kazakos EI, Kountouras J, Polyzos SA, Deretzi G. Novel aspects of defensins' involvement in virus-induced autoimmunity in the central nervous system. Med Hypotheses. 2017;102:33-36.
    • (2017) Med Hypotheses , vol.102 , pp. 33-36
    • Kazakos, E.I.1    Kountouras, J.2    Polyzos, S.A.3    Deretzi, G.4
  • 136
    • 0025349492 scopus 로고
    • Helicobacter pylori and the pathogenesis of gastroduodenal inflammation
    • Blaser MJ. Helicobacter pylori and the pathogenesis of gastroduodenal inflammation. J Infect Dis. 1990;161:626-633.
    • (1990) J Infect Dis , vol.161 , pp. 626-633
    • Blaser, M.J.1
  • 137
    • 0028766786 scopus 로고
    • NIH consensus development panel on helicobacter pylori in peptic ulcer disease
    • NIH Consensus Conference. Helicobacter pylori in peptic ulcer disease. NIH consensus development panel on helicobacter pylori in peptic ulcer disease. JAMA. 1994;272:65-69.
    • (1994) JAMA , vol.272 , pp. 65-69
  • 138
    • 2542472302 scopus 로고    scopus 로고
    • Pathogens as a cause of Alzheimer's disease
    • Kinoshita J. Pathogens as a cause of Alzheimer's disease. Neurobiol Aging. 2004;25:639-640.
    • (2004) Neurobiol Aging , vol.25 , pp. 639-640
    • Kinoshita, J.1
  • 139
    • 0031649594 scopus 로고    scopus 로고
    • Gastro-oesophageal reflux and Helicobacter pylori
    • Pace F, Bianchi Porro G. Gastro-oesophageal reflux and Helicobacter pylori. Ital J Gastroenterol Hepatol. 1998;30:S289-S293.
    • (1998) Ital J Gastroenterol Hepatol , vol.30 , pp. S289-S293
    • Pace, F.1    Bianchi Porro, G.2
  • 140
    • 84866305999 scopus 로고    scopus 로고
    • Helicobacter pylori infection might contribute to esophageal adenocarcinoma progress in subpopulations with gastroesophageal reflux disease and Barrett's esophagus
    • Kountouras J, Chatzopoulos D, Zavos C, et al. Helicobacter pylori infection might contribute to esophageal adenocarcinoma progress in subpopulations with gastroesophageal reflux disease and Barrett's esophagus. Helicobacter. 2012;17:402-403.
    • (2012) Helicobacter , vol.17 , pp. 402-403
    • Kountouras, J.1    Chatzopoulos, D.2    Zavos, C.3
  • 141
    • 33847268149 scopus 로고    scopus 로고
    • Eradication of Helicobacter pylori might halt the progress to oesophageal adenocarcinoma in patients with gastro-oesophageal reflux disease and Barrett's oesophagus
    • Kountouras J, Chatzopoulos D, Zavos C. Eradication of Helicobacter pylori might halt the progress to oesophageal adenocarcinoma in patients with gastro-oesophageal reflux disease and Barrett's oesophagus. Med Hypotheses. 2007;68:1174-1175.
    • (2007) Med Hypotheses , vol.68 , pp. 1174-1175
    • Kountouras, J.1    Chatzopoulos, D.2    Zavos, C.3
  • 143
    • 84920463325 scopus 로고    scopus 로고
    • Helicobacter pylori infection and gastroesophageal reflux disease - Barrett's esophagus sequence “dilemma
    • Kountouras J, Zavos C, Polyzos SA, Katsinelos P. Helicobacter pylori infection and gastroesophageal reflux disease - Barrett's esophagus sequence “dilemma”. Ann Gastroenterol. 2015;28:153.
    • (2015) Ann Gastroenterol , vol.28 , pp. 153
    • Kountouras, J.1    Zavos, C.2    Polyzos, S.A.3    Katsinelos, P.4
  • 144
    • 0035795998 scopus 로고    scopus 로고
    • Helicobacter pylori and symptomatic relapse of gastro-oesophageal reflux disease: a randomised controlled trial
    • Schwizer W, Thumshirn M, Dent J, et al. Helicobacter pylori and symptomatic relapse of gastro-oesophageal reflux disease: a randomised controlled trial. Lancet (London, England). 2001;357:1738-1742.
    • (2001) Lancet (London, England) , vol.357 , pp. 1738-1742
    • Schwizer, W.1    Thumshirn, M.2    Dent, J.3
  • 145
    • 23844468099 scopus 로고    scopus 로고
    • Should we test for Helicobacter pylori before treating gastroesophageal reflux disease?
    • Moayyedi P. Should we test for Helicobacter pylori before treating gastroesophageal reflux disease? Can J Gastroenterol. 2005;19:425-427.
    • (2005) Can J Gastroenterol , vol.19 , pp. 425-427
    • Moayyedi, P.1
  • 146
    • 34147195041 scopus 로고    scopus 로고
    • Risk of oesophageal cancer by histology among patients hospitalised for gastroduodenal ulcers
    • Bahmanyar S, Zendehdel K, Nyrén O, Ye W. Risk of oesophageal cancer by histology among patients hospitalised for gastroduodenal ulcers. Gut. 2007;56:464-468.
    • (2007) Gut , vol.56 , pp. 464-468
    • Bahmanyar, S.1    Zendehdel, K.2    Nyrén, O.3    Ye, W.4
  • 147
    • 84878115134 scopus 로고    scopus 로고
    • Helicobacter pylori infection-a boon or a bane: lessons from studies in a low-prevalence population
    • Lee YY, Mahendra Raj S, Graham DY. Helicobacter pylori infection-a boon or a bane: lessons from studies in a low-prevalence population. Helicobacter. 2013;18:338-346.
    • (2013) Helicobacter , vol.18 , pp. 338-346
    • Lee, Y.Y.1    Mahendra Raj, S.2    Graham, D.Y.3
  • 148
    • 0037382328 scopus 로고    scopus 로고
    • Helicobacter pylori is not and never was “protective” against anything, including GERD
    • Graham DY. Helicobacter pylori is not and never was “protective” against anything, including GERD. Dig Dis Sci. 2003;48:629-630.
    • (2003) Dig Dis Sci , vol.48 , pp. 629-630
    • Graham, D.Y.1
  • 149
    • 84945451378 scopus 로고    scopus 로고
    • Guidelines for the management of Helicobacter pylori infection in Italy: The III Working Group Consensus Report 2015
    • Zagari RM, Romano M, Ojetti V, et al. Guidelines for the management of Helicobacter pylori infection in Italy: The III Working Group Consensus Report 2015. Dig Liver Dis. 2015;47:903-912.
    • (2015) Dig Liver Dis , vol.47 , pp. 903-912
    • Zagari, R.M.1    Romano, M.2    Ojetti, V.3
  • 150
    • 13844310347 scopus 로고    scopus 로고
    • Association between Helicobacter pylori infection and acute inflammatory demyelinating polyradiculoneuropathy
    • Kountouras J, Deretzi G, Zavos C, et al. Association between Helicobacter pylori infection and acute inflammatory demyelinating polyradiculoneuropathy. Eur J Neurol. 2005;12:139-143.
    • (2005) Eur J Neurol , vol.12 , pp. 139-143
    • Kountouras, J.1    Deretzi, G.2    Zavos, C.3
  • 151
    • 0028431004 scopus 로고
    • Relation of Helicobacter pylori infection and coronary heart disease
    • Mendall MA, Goggin PM, Molineaux N, et al. Relation of Helicobacter pylori infection and coronary heart disease. Br Heart J. 1994;71:437-439.
    • (1994) Br Heart J , vol.71 , pp. 437-439
    • Mendall, M.A.1    Goggin, P.M.2    Molineaux, N.3
  • 152
    • 0030779815 scopus 로고    scopus 로고
    • What remaining questions regarding Helicobacter pylori and associated diseases should be addressed by future research? View from Europe
    • McColl KE. What remaining questions regarding Helicobacter pylori and associated diseases should be addressed by future research? View from Europe Gastroenterology. 1997;113(6 Suppl):S158-S162.
    • (1997) Gastroenterology , vol.113 , Issue.6 , pp. S158-S162
    • McColl, K.E.1
  • 153
    • 0037054035 scopus 로고    scopus 로고
    • Eradication of Helicobacter pylori may be beneficial in the management of chronic open-angle glaucoma
    • Kountouras J, Mylopoulos N, Chatzopoulos D, et al. Eradication of Helicobacter pylori may be beneficial in the management of chronic open-angle glaucoma. Arch Intern Med. 2002;162:1237-1244.
    • (2002) Arch Intern Med , vol.162 , pp. 1237-1244
    • Kountouras, J.1    Mylopoulos, N.2    Chatzopoulos, D.3
  • 154
    • 0034604242 scopus 로고    scopus 로고
    • Serum soluble heat shock protein 60 is elevated in subjects with atherosclerosis in a general population
    • Xu Q, Schett G, Perschinka H, et al. Serum soluble heat shock protein 60 is elevated in subjects with atherosclerosis in a general population. Circulation. 2000;102:14-20.
    • (2000) Circulation , vol.102 , pp. 14-20
    • Xu, Q.1    Schett, G.2    Perschinka, H.3
  • 155
    • 13244278162 scopus 로고    scopus 로고
    • Association between chronic Helicobacter pylori infection and acute ischemic stroke: Fukuoka Harasanshin Atherosclerosis Trial (FHAT)
    • Sawayama Y, Ariyama I, Hamada M, et al. Association between chronic Helicobacter pylori infection and acute ischemic stroke: Fukuoka Harasanshin Atherosclerosis Trial (FHAT). Atherosclerosis. 2005;178 2:303-309.
    • (2005) Atherosclerosis , vol.178 , Issue.2 , pp. 303-309
    • Sawayama, Y.1    Ariyama, I.2    Hamada, M.3
  • 156
    • 85011317366 scopus 로고    scopus 로고
    • Metabolic syndrome and the cellular phase of Alzheimer's disease
    • Pugazhenthi S. Metabolic syndrome and the cellular phase of Alzheimer's disease. Prog Mol Biol Transl Sci. 2017;146:243-258.
    • (2017) Prog Mol Biol Transl Sci , vol.146 , pp. 243-258
    • Pugazhenthi, S.1
  • 157
    • 33845468713 scopus 로고    scopus 로고
    • Insulin resistance syndrome and Alzheimer disease: pathophysiologic mechanisms and therapeutic implications
    • Craft S. Insulin resistance syndrome and Alzheimer disease: pathophysiologic mechanisms and therapeutic implications. Alzheimer Dis Assoc Disord. 2006;20 4:298-301.
    • (2006) Alzheimer Dis Assoc Disord , vol.20 , Issue.4 , pp. 298-301
    • Craft, S.1
  • 158
    • 0037338557 scopus 로고    scopus 로고
    • Is breakdown of the blood-brain barrier responsible for lacunar stroke, leukoaraiosis, and dementia?
    • Wardlaw JM, Sandercock PAG, Dennis MS, Starr J. Is breakdown of the blood-brain barrier responsible for lacunar stroke, leukoaraiosis, and dementia? Stroke. 2003;34 3:806-812.
    • (2003) Stroke , vol.34 , Issue.3 , pp. 806-812
    • Wardlaw, J.M.1    Sandercock, P.A.G.2    Dennis, M.S.3    Starr, J.4
  • 159
    • 0025870546 scopus 로고
    • Blood-brain-barrier in a geriatric population: barrier function in degenerative and vascular dementias
    • Mecocci P, Parnetti L, Reboldi GP, et al. Blood-brain-barrier in a geriatric population: barrier function in degenerative and vascular dementias. Acta Neurol Scand. 1991;84 3:210-213.
    • (1991) Acta Neurol Scand , vol.84 , Issue.3 , pp. 210-213
    • Mecocci, P.1    Parnetti, L.2    Reboldi, G.P.3
  • 160
    • 0031026879 scopus 로고    scopus 로고
    • Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study
    • Hofman A, Ott A, Breteler MM, et al. Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study. Lancet (London, England). 1997;349 9046:151-154.
    • (1997) Lancet (London, England) , vol.349 , Issue.9046 , pp. 151-154
    • Hofman, A.1    Ott, A.2    Breteler, M.M.3
  • 161
    • 0033668944 scopus 로고    scopus 로고
    • Evidence that Alzheimer's disease is a microvascular disorder: the role of constitutive nitric oxide
    • de la Torre JC, Stefano GB. Evidence that Alzheimer's disease is a microvascular disorder: the role of constitutive nitric oxide. Brain Res Brain Res Rev. 2000;34 3:119-136.
    • (2000) Brain Res Brain Res Rev , vol.34 , Issue.3 , pp. 119-136
    • de la Torre, J.C.1    Stefano, G.B.2
  • 162
    • 84931004209 scopus 로고    scopus 로고
    • Cognitive and functional decline in patients with mild Alzheimer dementia with or without comorbid diabetes
    • Ascher-Svanum H, Chen Y-F, Hake A, et al. Cognitive and functional decline in patients with mild Alzheimer dementia with or without comorbid diabetes. Clin Ther. 2015;37 6:1195-1205.
    • (2015) Clin Ther , vol.37 , Issue.6 , pp. 1195-1205
    • Ascher-Svanum, H.1    Chen, Y.-F.2    Hake, A.3
  • 163
    • 0031046204 scopus 로고    scopus 로고
    • Why are stroke patients prone to develop dementia?
    • Pasquier F, Leys D. Why are stroke patients prone to develop dementia? J Neurol. 1997;244 3:135-142.
    • (1997) J Neurol , vol.244 , Issue.3 , pp. 135-142
    • Pasquier, F.1    Leys, D.2
  • 164
    • 12844251393 scopus 로고    scopus 로고
    • Helicobacter pylori induces transendothelial migration of activated memory T cells
    • Enarsson K, Brisslert M, Backert S, Quiding-Järbrink M. Helicobacter pylori induces transendothelial migration of activated memory T cells. Infect Immun. 2005;73 2:761-769.
    • (2005) Infect Immun , vol.73 , Issue.2 , pp. 761-769
    • Enarsson, K.1    Brisslert, M.2    Backert, S.3    Quiding-Järbrink, M.4
  • 166
    • 3142778515 scopus 로고    scopus 로고
    • Human dendritic cells respond to Helicobacter pylori, promoting NK cell and Th1-effector responses in vitro
    • Hafsi N, Voland P, Schwendy S, et al. Human dendritic cells respond to Helicobacter pylori, promoting NK cell and Th1-effector responses in vitro. J Immunol. 2004;173 2:1249-1257.
    • (2004) J Immunol , vol.173 , Issue.2 , pp. 1249-1257
    • Hafsi, N.1    Voland, P.2    Schwendy, S.3
  • 167
    • 21544473553 scopus 로고    scopus 로고
    • Impact of Helicobacter pylori virulence factors and compounds on activation and maturation of human dendritic cells
    • Kranzer K, Söllner L, Aigner M, et al. Impact of Helicobacter pylori virulence factors and compounds on activation and maturation of human dendritic cells. Infect Immun. 2005;73 7:4180-4189.
    • (2005) Infect Immun , vol.73 , Issue.7 , pp. 4180-4189
    • Kranzer, K.1    Söllner, L.2    Aigner, M.3
  • 168
    • 25444519483 scopus 로고    scopus 로고
    • Helicobacter pylori outer membrane protein 18 (Hp1125) induces dendritic cell maturation and function
    • Rathinavelu S, Kao JY, Zavros Y, Merchant JL. Helicobacter pylori outer membrane protein 18 (Hp1125) induces dendritic cell maturation and function. Helicobacter. 2005;10 5:424-432.
    • (2005) Helicobacter , vol.10 , Issue.5 , pp. 424-432
    • Rathinavelu, S.1    Kao, J.Y.2    Zavros, Y.3    Merchant, J.L.4
  • 169
    • 0038649658 scopus 로고    scopus 로고
    • Antigenic properties of HpaA and Omp18, two outer membrane proteins of Helicobacter pylori
    • Voland P, Hafsi N, Zeitner M, Laforsch S, Wagner H, Prinz C. Antigenic properties of HpaA and Omp18, two outer membrane proteins of Helicobacter pylori. Infect Immun. 2003;71 7:3837-3843.
    • (2003) Infect Immun , vol.71 , Issue.7 , pp. 3837-3843
    • Voland, P.1    Hafsi, N.2    Zeitner, M.3    Laforsch, S.4    Wagner, H.5    Prinz, C.6
  • 170
    • 77957268623 scopus 로고    scopus 로고
    • Interplay between Helicobacter pylori and immune cells in immune pathogenesis of gastric inflammation and mucosal pathology
    • Tsai H-F, Hsu P-N. Interplay between Helicobacter pylori and immune cells in immune pathogenesis of gastric inflammation and mucosal pathology. Cell Mol Immunol. 2010;7 4:255-259.
    • (2010) Cell Mol Immunol , vol.7 , Issue.4 , pp. 255-259
    • Tsai, H.-F.1    Hsu, P.-N.2
  • 171
    • 0038392813 scopus 로고    scopus 로고
    • TNF-alpha induces apoptosis of parietal cells
    • Neu B, Puschmann AJ, Mayerhofer A, et al. TNF-alpha induces apoptosis of parietal cells. BiochemPharmacol. 2003;65 10:1755-1760.
    • (2003) BiochemPharmacol , vol.65 , Issue.10 , pp. 1755-1760
    • Neu, B.1    Puschmann, A.J.2    Mayerhofer, A.3
  • 172
    • 33746119225 scopus 로고    scopus 로고
    • Low multiplicity of infection of Helicobacter pylori suppresses apoptosis of B lymphocytes
    • Bussiere FI, Chaturvedi R, Asim M, et al. Low multiplicity of infection of Helicobacter pylori suppresses apoptosis of B lymphocytes. Cancer Res. 2006;66 13:6834-6842.
    • (2006) Cancer Res , vol.66 , Issue.13 , pp. 6834-6842
    • Bussiere, F.I.1    Chaturvedi, R.2    Asim, M.3
  • 173
    • 0034102184 scopus 로고    scopus 로고
    • Helicobacter pylori induces apoptosis in gastric epithelial cells through inducible nitric oxide
    • Watanabe S, Takagi A, Koga Y, Kamiya S, Miwa T. Helicobacter pylori induces apoptosis in gastric epithelial cells through inducible nitric oxide. J Gastroenterol Hepatol. 2000;15 2:168-174.
    • (2000) J Gastroenterol Hepatol , vol.15 , Issue.2 , pp. 168-174
    • Watanabe, S.1    Takagi, A.2    Koga, Y.3    Kamiya, S.4    Miwa, T.5
  • 174
    • 0036937774 scopus 로고    scopus 로고
    • Significance of the caspase family in Helicobacter pylori induced gastric epithelial apoptosis
    • Potthoff A, Ledig S, Martin J, et al. Significance of the caspase family in Helicobacter pylori induced gastric epithelial apoptosis. Helicobacter. 2002;7 6:367-377.
    • (2002) Helicobacter , vol.7 , Issue.6 , pp. 367-377
    • Potthoff, A.1    Ledig, S.2    Martin, J.3
  • 175
    • 0036100766 scopus 로고    scopus 로고
    • Analysis of apoptotic and antiapoptotic signalling pathways induced by Helicobacter pylori
    • Maeda S, Yoshida H, Mitsuno Y, et al. Analysis of apoptotic and antiapoptotic signalling pathways induced by Helicobacter pylori. Gut. 2002;50 6:771-778.
    • (2002) Gut , vol.50 , Issue.6 , pp. 771-778
    • Maeda, S.1    Yoshida, H.2    Mitsuno, Y.3
  • 176
    • 27944467437 scopus 로고    scopus 로고
    • Effect of Helicobacter pylori infection on Bax protein expression in patients with gastric precancerous lesions
    • Liu HF, Liu WW, Wang GA, Teng XC. Effect of Helicobacter pylori infection on Bax protein expression in patients with gastric precancerous lesions. World J Gastroenterol. 2005;11 37:5899-5901.
    • (2005) World J Gastroenterol , vol.11 , Issue.37 , pp. 5899-5901
    • Liu, H.F.1    Liu, W.W.2    Wang, G.A.3    Teng, X.C.4
  • 177
    • 33744960020 scopus 로고    scopus 로고
    • Helicobacter pylori vacuolating cytotoxin induces activation of the proapoptotic proteins Bax and Bak, leading to cytochrome c release and cell death, independent of vacuolation
    • Yamasaki E, Wada A, Kumatori A, et al. Helicobacter pylori vacuolating cytotoxin induces activation of the proapoptotic proteins Bax and Bak, leading to cytochrome c release and cell death, independent of vacuolation. J Biol Chem. 2006;281 16:11250-11259.
    • (2006) J Biol Chem , vol.281 , Issue.16 , pp. 11250-11259
    • Yamasaki, E.1    Wada, A.2    Kumatori, A.3
  • 178
    • 1542270754 scopus 로고    scopus 로고
    • Expression of nitric oxide system in clinically evaluated cases of Alzheimer's disease
    • Fernández-Vizarra P, Fernández AP, Castro-Blanco S, et al. Expression of nitric oxide system in clinically evaluated cases of Alzheimer's disease. Neurobiol Dis. 2004;15 2:287-305.
    • (2004) Neurobiol Dis , vol.15 , Issue.2 , pp. 287-305
    • Fernández-Vizarra, P.1    Fernández, A.P.2    Castro-Blanco, S.3
  • 179
    • 84949969049 scopus 로고    scopus 로고
    • Getting to NO Alzheimer's disease: Neuroprotection versus neurotoxicity mediated by nitric oxide
    • Balez R, Ooi L. Getting to NO Alzheimer's disease: Neuroprotection versus neurotoxicity mediated by nitric oxide. Oxid Med Cell Longev. 2016;2016:1-8.
    • (2016) Oxid Med Cell Longev , vol.2016 , pp. 1-8
    • Balez, R.1    Ooi, L.2
  • 180
    • 0034657707 scopus 로고    scopus 로고
    • The mechanisms of hsp27 antibody-mediated apoptosis in retinal neuronal cells
    • Tezel G, Wax MB. The mechanisms of hsp27 antibody-mediated apoptosis in retinal neuronal cells. J Neurosci. 2000;20 10:3552-3562.
    • (2000) J Neurosci , vol.20 , Issue.10 , pp. 3552-3562
    • Tezel, G.1    Wax, M.B.2
  • 181
    • 0033949558 scopus 로고    scopus 로고
    • Significant increase in antigastric autoantibodies in a long-term follow-up study of H. pylori gastritis
    • Vorobjova T, Faller G, Maaroos HI, et al. Significant increase in antigastric autoantibodies in a long-term follow-up study of H. pylori gastritis. Virchows Arch. 2000;437 1:37-45.
    • (2000) Virchows Arch , vol.437 , Issue.1 , pp. 37-45
    • Vorobjova, T.1    Faller, G.2    Maaroos, H.I.3
  • 182
    • 0029811855 scopus 로고    scopus 로고
    • Antigenic mimicry between Helicobacter pylori and gastric mucosa in the pathogenesis of body atrophic gastritis
    • Negrini R, Savio A, Poiesi C, et al. Antigenic mimicry between Helicobacter pylori and gastric mucosa in the pathogenesis of body atrophic gastritis. Gastroenterology. 1996;111 3:655-665.
    • (1996) Gastroenterology , vol.111 , Issue.3 , pp. 655-665
    • Negrini, R.1    Savio, A.2    Poiesi, C.3
  • 183
    • 0031057931 scopus 로고    scopus 로고
    • Implications of Helicobacter pylori serological titer for the histological severity of antral gastritis
    • Sheu BS, Shiesh SC, Yang HB, Su IJ, Chen CY, Lin XZ. Implications of Helicobacter pylori serological titer for the histological severity of antral gastritis. Endoscopy. 1997;29 1:27-30.
    • (1997) Endoscopy , vol.29 , Issue.1 , pp. 27-30
    • Sheu, B.S.1    Shiesh, S.C.2    Yang, H.B.3    Su, I.J.4    Chen, C.Y.5    Lin, X.Z.6
  • 184
    • 75449083209 scopus 로고    scopus 로고
    • Association of autoimmune type atrophic corpus gastritis with Helicobacter pylori infection
    • Veijola LI, Oksanen AM, Sipponen PI, Rautelin HIK. Association of autoimmune type atrophic corpus gastritis with Helicobacter pylori infection. World J Gastroenterol. 2010;16 1:83-88.
    • (2010) World J Gastroenterol , vol.16 , Issue.1 , pp. 83-88
    • Veijola, L.I.1    Oksanen, A.M.2    Sipponen, P.I.3    Rautelin, H.I.K.4
  • 185
    • 0034984992 scopus 로고    scopus 로고
    • Molecular mimicry in Campylobacter jejuni and Helicobacter pylori lipopolysaccharides: contribution of gastrointestinal infections to autoimmunity
    • Moran AP, Prendergast MM. Molecular mimicry in Campylobacter jejuni and Helicobacter pylori lipopolysaccharides: contribution of gastrointestinal infections to autoimmunity. J Autoimmun. 2001;16 3:241-256.
    • (2001) J Autoimmun , vol.16 , Issue.3 , pp. 241-256
    • Moran, A.P.1    Prendergast, M.M.2
  • 186
    • 0031755896 scopus 로고    scopus 로고
    • Antibodies against Helicobacter pylori were detected in the cerebrospinal fluid obtained from patients with Guillain-Barré syndrome
    • Chiba S, Sugiyama T, Matsumoto H, et al. Antibodies against Helicobacter pylori were detected in the cerebrospinal fluid obtained from patients with Guillain-Barré syndrome. Ann Neurol. 1998;44 4:686-688.
    • (1998) Ann Neurol , vol.44 , Issue.4 , pp. 686-688
    • Chiba, S.1    Sugiyama, T.2    Matsumoto, H.3
  • 187
    • 0036297473 scopus 로고    scopus 로고
    • An antibody to VacA of Helicobacter pylori in cerebrospinal fluid from patients with Guillain-Barre syndrome
    • Chiba S, Sugiyama T, Yonekura K, et al. An antibody to VacA of Helicobacter pylori in cerebrospinal fluid from patients with Guillain-Barre syndrome. J Neurol Neurosurg Psychiatry. 2002;73 1:76-78.
    • (2002) J Neurol Neurosurg Psychiatry , vol.73 , Issue.1 , pp. 76-78
    • Chiba, S.1    Sugiyama, T.2    Yonekura, K.3
  • 189
    • 0347531785 scopus 로고    scopus 로고
    • Increased levels of Helicobacter pylori IgG antibodies in aqueous humor of patients with primary open-angle and exfoliation glaucoma
    • Kountouras J, Mylopoulos N, Konstas AGP, Zavos C, Chatzopoulos D, Boukla A. Increased levels of Helicobacter pylori IgG antibodies in aqueous humor of patients with primary open-angle and exfoliation glaucoma. Graefe's Arch Clin Exp Ophthalmol. 2003;241 11:884-890.
    • (2003) Graefe's Arch Clin Exp Ophthalmol , vol.241 , Issue.11 , pp. 884-890
    • Kountouras, J.1    Mylopoulos, N.2    Konstas, A.G.P.3    Zavos, C.4    Chatzopoulos, D.5    Boukla, A.6
  • 190
    • 84950120525 scopus 로고    scopus 로고
    • Olfactory bulb proteome dynamics during the progression of sporadic Alzheimer's disease: identification of common and distinct olfactory targets across Alzheimer-related co-pathologies
    • Zelaya MV, Pérez-Valderrama E, de Morentin XM, et al. Olfactory bulb proteome dynamics during the progression of sporadic Alzheimer's disease: identification of common and distinct olfactory targets across Alzheimer-related co-pathologies. Oncotarget. 2015;6 37:39437-39456.
    • (2015) Oncotarget , vol.6 , Issue.37 , pp. 39437-39456
    • Zelaya, M.V.1    Pérez-Valderrama, E.2    de Morentin, X.M.3
  • 191
    • 84896545563 scopus 로고    scopus 로고
    • Olfactory bulb involvement in neurodegenerative diseases
    • Attems J, Walker L, Jellinger KA. Olfactory bulb involvement in neurodegenerative diseases. Acta Neuropathol. 2014;127 4:459-475.
    • (2014) Acta Neuropathol , vol.127 , Issue.4 , pp. 459-475
    • Attems, J.1    Walker, L.2    Jellinger, K.A.3
  • 192
    • 84994388449 scopus 로고    scopus 로고
    • Olfactory identification deficits, cognitive decline, and dementia in older adults
    • Devanand DP. Olfactory identification deficits, cognitive decline, and dementia in older adults. Am J Geriatr Psychiatry. 2016;24 12:1151-1157.
    • (2016) Am J Geriatr Psychiatry , vol.24 , Issue.12 , pp. 1151-1157
    • Devanand, D.P.1
  • 193
    • 84935000313 scopus 로고    scopus 로고
    • Olfactory dysfunction in the elderly: basic circuitry and alterations with normal aging and Alzheimer's disease
    • Masurkar AV, Devanand DP. Olfactory dysfunction in the elderly: basic circuitry and alterations with normal aging and Alzheimer's disease. Curr Geriatr Reports. 2014;3 2:91-100.
    • (2014) Curr Geriatr Reports , vol.3 , Issue.2 , pp. 91-100
    • Masurkar, A.V.1    Devanand, D.P.2
  • 194
    • 0035847617 scopus 로고    scopus 로고
    • Olfactory centres in Alzheimer's disease: olfactory bulb is involved in early Braak's stages
    • Kovács T, Cairns NJ, Lantos PL. Olfactory centres in Alzheimer's disease: olfactory bulb is involved in early Braak's stages. NeuroReport. 2001;12 2:285-288.
    • (2001) NeuroReport , vol.12 , Issue.2 , pp. 285-288
    • Kovács, T.1    Cairns, N.J.2    Lantos, P.L.3
  • 195
    • 77951723978 scopus 로고    scopus 로고
    • Olfactory epithelium amyloid-beta and paired helical filament-tau pathology in Alzheimer disease
    • Arnold SE, Lee EB, Moberg PJ, et al. Olfactory epithelium amyloid-beta and paired helical filament-tau pathology in Alzheimer disease. Ann Neurol. 2010;67 4:462-469.
    • (2010) Ann Neurol , vol.67 , Issue.4 , pp. 462-469
    • Arnold, S.E.1    Lee, E.B.2    Moberg, P.J.3
  • 196
    • 67650872890 scopus 로고    scopus 로고
    • MRI-derived atrophy of the olfactory bulb and tract in mild cognitive impairment and Alzheimer's disease
    • Thomann PA, Dos Santos V, Seidl U, Toro P, Essig M, Schröder J. MRI-derived atrophy of the olfactory bulb and tract in mild cognitive impairment and Alzheimer's disease. J Alzheimers Dis. 2009;17 1:213-221.
    • (2009) J Alzheimers Dis , vol.17 , Issue.1 , pp. 213-221
    • Thomann, P.A.1    Dos Santos, V.2    Seidl, U.3    Toro, P.4    Essig, M.5    Schröder, J.6
  • 197
    • 78650828988 scopus 로고    scopus 로고
    • Functional representation of olfactory impairment in early Alzheimer's disease
    • Förster S, Vaitl A, Teipel SJ, et al. Functional representation of olfactory impairment in early Alzheimer's disease. J Alzheimers Dis. 2010;22 2:581-591.
    • (2010) J Alzheimers Dis , vol.22 , Issue.2 , pp. 581-591
    • Förster, S.1    Vaitl, A.2    Teipel, S.J.3
  • 198
    • 84985893103 scopus 로고    scopus 로고
    • Helicobacter pylori and its reservoirs: A correlation with the gastric infection
    • Payão SLM, Rasmussen LT. Helicobacter pylori and its reservoirs: A correlation with the gastric infection. World J Gastrointest Pharmacol Ther. 2016;7 1:126-132.
    • (2016) World J Gastrointest Pharmacol Ther , vol.7 , Issue.1 , pp. 126-132
    • Payão, S.L.M.1    Rasmussen, L.T.2
  • 199
    • 38549139216 scopus 로고    scopus 로고
    • Detection of Helicobacter pylori by polymerase chain reaction in the subgingival biofilm and saliva of non-dyspeptic periodontal patients
    • Souto R, Colombo APV. Detection of Helicobacter pylori by polymerase chain reaction in the subgingival biofilm and saliva of non-dyspeptic periodontal patients. J Periodontol. 2008;79 1:97-103.
    • (2008) J Periodontol , vol.79 , Issue.1 , pp. 97-103
    • Souto, R.1    Colombo, A.P.V.2
  • 200
    • 84924324912 scopus 로고    scopus 로고
    • The frequency of Helicobacter pylori in dental plaque is possibly underestimated
    • Amiri N, Abiri R, Eyvazi M, Zolfaghari MR, Alvandi A. The frequency of Helicobacter pylori in dental plaque is possibly underestimated. Arch Oral Biol. 2015;60 5:782-788.
    • (2015) Arch Oral Biol , vol.60 , Issue.5 , pp. 782-788
    • Amiri, N.1    Abiri, R.2    Eyvazi, M.3    Zolfaghari, M.R.4    Alvandi, A.5
  • 201
    • 33645745277 scopus 로고    scopus 로고
    • Prevalence study to elucidate the transmission pathways of Helicobacter pylori at oral and gastroduodenal sites of a South Indian population
    • Ahmed KS, Khan AA, Ahmed I, et al. Prevalence study to elucidate the transmission pathways of Helicobacter pylori at oral and gastroduodenal sites of a South Indian population. Singapore Med J. 2006;47 4:291-296.
    • (2006) Singapore Med J , vol.47 , Issue.4 , pp. 291-296
    • Ahmed, K.S.1    Khan, A.A.2    Ahmed, I.3
  • 202
    • 66049129886 scopus 로고    scopus 로고
    • Detection of cytotoxin genotypes of Helicobacter pylori in stomach, saliva and dental plaque
    • Silva DG, Stevens RH, Macedo JMB, et al. Detection of cytotoxin genotypes of Helicobacter pylori in stomach, saliva and dental plaque. Arch Oral Biol. 2009;54 7:684-688.
    • (2009) Arch Oral Biol , vol.54 , Issue.7 , pp. 684-688
    • Silva, D.G.1    Stevens, R.H.2    Macedo, J.M.B.3
  • 203
    • 84961601399 scopus 로고    scopus 로고
    • The presence of Helicobacter pylori in oral cavities of patients with leukoplakia and oral lichen planus
    • Kazanowska-Dygdała M, Duś I, Radwan-Oczko M. The presence of Helicobacter pylori in oral cavities of patients with leukoplakia and oral lichen planus. J Appl Oral Sci. 2016;24 1:18-23.
    • (2016) J Appl Oral Sci , vol.24 , Issue.1 , pp. 18-23
    • Kazanowska-Dygdała, M.1    Duś, I.2    Radwan-Oczko, M.3
  • 205
    • 84978267818 scopus 로고    scopus 로고
    • Common mechanisms involved in Alzheimer's disease and type 2 diabetes: a key role of chronic bacterial infection and inflammation
    • Miklossy J, McGeer PL. Common mechanisms involved in Alzheimer's disease and type 2 diabetes: a key role of chronic bacterial infection and inflammation. Aging (Albany NY). 2016;8 4:575-588.
    • (2016) Aging (Albany NY) , vol.8 , Issue.4 , pp. 575-588
    • Miklossy, J.1    McGeer, P.L.2
  • 206
    • 84867006016 scopus 로고    scopus 로고
    • Glaucoma and Helicobacter pylori: eyes “wide open”!
    • author reply 963
    • Kountouras J, Zavos C, Katsinelos P, Vardaka E. Glaucoma and Helicobacter pylori: eyes “wide open”!. Dig Liver Dis. 2012;44 11:962-963; author reply 963.
    • (2012) Dig Liver Dis , vol.44 , Issue.11 , pp. 962-963
    • Kountouras, J.1    Zavos, C.2    Katsinelos, P.3    Vardaka, E.4
  • 207
    • 84948752736 scopus 로고    scopus 로고
    • The association between primary open angle glaucoma and clustered components of metabolic syndrome
    • Rasoulinejad SA, Kasiri A, Montazeri M, et al. The association between primary open angle glaucoma and clustered components of metabolic syndrome. Open Ophthalmol J. 2015;9:149-155.
    • (2015) Open Ophthalmol J , vol.9 , pp. 149-155
    • Rasoulinejad, S.A.1    Kasiri, A.2    Montazeri, M.3
  • 208
    • 80053946733 scopus 로고    scopus 로고
    • Gastrointestinal immune system and brain dialogue implicated in neuroinflammatory and neurodegenerative diseases
    • Deretzi G, Kountouras J, Polyzos SA, et al. Gastrointestinal immune system and brain dialogue implicated in neuroinflammatory and neurodegenerative diseases. Curr Mol Med. 2011;11 8:696-707.
    • (2011) Curr Mol Med , vol.11 , Issue.8 , pp. 696-707
    • Deretzi, G.1    Kountouras, J.2    Polyzos, S.A.3
  • 209
    • 84943152592 scopus 로고    scopus 로고
    • The gut-brain axis: Interactions between Helicobacter pylori and enteric and central nervous systems
    • Kountouras J, Zavos C, Polyzos SA, Deretzi G. The gut-brain axis: Interactions between Helicobacter pylori and enteric and central nervous systems. Ann Gastroenterol. 2015;28 4:506.
    • (2015) Ann Gastroenterol , vol.28 , Issue.4 , pp. 506
    • Kountouras, J.1    Zavos, C.2    Polyzos, S.A.3    Deretzi, G.4
  • 210
    • 70350456131 scopus 로고    scopus 로고
    • Helicobacter pylori: an intruder involved in conspiring glaucomatous neuropathy
    • Kountouras J. Helicobacter pylori: an intruder involved in conspiring glaucomatous neuropathy. Br J Ophthalmol. 2009;93 11:1413-1415.
    • (2009) Br J Ophthalmol , vol.93 , Issue.11 , pp. 1413-1415
    • Kountouras, J.1
  • 211
    • 70350447989 scopus 로고    scopus 로고
    • Glaucoma and Helicobacter pylori infection: correlations and controversies
    • Izzotti A, Saccà SC, Bagnis A, Recupero SM. Glaucoma and Helicobacter pylori infection: correlations and controversies. Br J Ophthalmol. 2009;93 11:1420-1427.
    • (2009) Br J Ophthalmol , vol.93 , Issue.11 , pp. 1420-1427
    • Izzotti, A.1    Saccà, S.C.2    Bagnis, A.3    Recupero, S.M.4
  • 212
    • 85022185356 scopus 로고    scopus 로고
    • Amyloid burden in obstructive sleep apnea
    • Yun C-H, Lee H-Y, Lee SK, et al. Amyloid burden in obstructive sleep apnea. J Alzheimers Dis. 2017;59 1:21-29.
    • (2017) J Alzheimers Dis , vol.59 , Issue.1 , pp. 21-29
    • Yun, C.-H.1    Lee, H.-Y.2    Lee, S.K.3
  • 213
    • 63449112701 scopus 로고    scopus 로고
    • Virulence factor genotypes of Helicobacter pylori affect cure rates of eradication therapy
    • Sugimoto M, Yamaoka Y. Virulence factor genotypes of Helicobacter pylori affect cure rates of eradication therapy. Arch Immunol Ther Exp (Warsz). 2009;57 1:45-56.
    • (2009) Arch Immunol Ther Exp (Warsz) , vol.57 , Issue.1 , pp. 45-56
    • Sugimoto, M.1    Yamaoka, Y.2
  • 214
    • 0033001107 scopus 로고    scopus 로고
    • Serum tumour necrosis factor-alpha is increased in patients with Helicobacter pylori infection and CagA antibodies
    • Perri F, Clemente R, Festa V, et al. Serum tumour necrosis factor-alpha is increased in patients with Helicobacter pylori infection and CagA antibodies. Ital J Gastroenterol Hepatol. 1999;31 4:290-294.
    • (1999) Ital J Gastroenterol Hepatol , vol.31 , Issue.4 , pp. 290-294
    • Perri, F.1    Clemente, R.2    Festa, V.3
  • 216
    • 84986232845 scopus 로고    scopus 로고
    • A potential impact of Helicobacter pylori infection on minimal hepatic encephalopathy pathobiology
    • Kountouras J, Polyzos SA, Gavalas E, et al. A potential impact of Helicobacter pylori infection on minimal hepatic encephalopathy pathobiology. J Gastrointestin Liver Dis. 2016;25 3:405-406.
    • (2016) J Gastrointestin Liver Dis , vol.25 , Issue.3 , pp. 405-406
    • Kountouras, J.1    Polyzos, S.A.2    Gavalas, E.3
  • 217
    • 67649285714 scopus 로고    scopus 로고
    • Interaction between Helicobacter pylori, diet, and genetic polymorphisms as related to non-cancer diseases
    • Izzotti A, Durando P, Ansaldi F, Gianiorio F, Pulliero A. Interaction between Helicobacter pylori, diet, and genetic polymorphisms as related to non-cancer diseases. Mutat Res. 2009;667 1-2:142-157.
    • (2009) Mutat Res , vol.667 , Issue.1-2 , pp. 142-157
    • Izzotti, A.1    Durando, P.2    Ansaldi, F.3    Gianiorio, F.4    Pulliero, A.5
  • 219
    • 84907717011 scopus 로고    scopus 로고
    • Pathogens penetrating the central nervous system: infection pathways and the cellular and molecular mechanisms of invasion
    • Dando SJ, Mackay-Sim A, Norton R, et al. Pathogens penetrating the central nervous system: infection pathways and the cellular and molecular mechanisms of invasion. Clin Microbiol Rev. 2014;27 4:691-726.
    • (2014) Clin Microbiol Rev , vol.27 , Issue.4 , pp. 691-726
    • Dando, S.J.1    Mackay-Sim, A.2    Norton, R.3
  • 220
    • 78449282143 scopus 로고    scopus 로고
    • Chlamydia pneumoniae infection and Alzheimer's disease: a connection to remember?
    • Shima K, Kuhlenbäumer G, Rupp J. Chlamydia pneumoniae infection and Alzheimer's disease: a connection to remember? Med Microbiol Immunol. 2010;199 4:283-289.
    • (2010) Med Microbiol Immunol , vol.199 , Issue.4 , pp. 283-289
    • Shima, K.1    Kuhlenbäumer, G.2    Rupp, J.3
  • 221
    • 84878795282 scopus 로고    scopus 로고
    • Could past Chlamydial vascular infection promote the dissemination of Chlamydia pneumoniae to the brain?
    • Di Pietro M, Filardo S, Cazzavillan S, et al. Could past Chlamydial vascular infection promote the dissemination of Chlamydia pneumoniae to the brain? J Biol Regul Homeost Agents. 2015;27 1:155-164.
    • (2015) J Biol Regul Homeost Agents , vol.27 , Issue.1 , pp. 155-164
    • Di Pietro, M.1    Filardo, S.2    Cazzavillan, S.3
  • 222
    • 79955679943 scopus 로고    scopus 로고
    • Helicobacter pylori infection may trigger Guillain-Barré syndrome, Fisher syndrome and Bickerstaff brainstem encephalitis
    • author reply 169
    • Kountouras J, Deretzi G, Zavos C, et al. Helicobacter pylori infection may trigger Guillain-Barré syndrome, Fisher syndrome and Bickerstaff brainstem encephalitis. J Neurol Sci. 2011;305 1-2:167-168; author reply 169.
    • (2011) J Neurol Sci , vol.305 , Issue.1-2 , pp. 167-168
    • Kountouras, J.1    Deretzi, G.2    Zavos, C.3
  • 223
    • 85011756092 scopus 로고    scopus 로고
    • Mast Cell - Glia dialogue in chronic pain and neuropathic pain: blood-brain barrier implications
    • Skaper SD. Mast Cell - Glia dialogue in chronic pain and neuropathic pain: blood-brain barrier implications. CNS Neurol Disord Drug Targets. 2016;15 9:1072-1078.
    • (2016) CNS Neurol Disord Drug Targets , vol.15 , Issue.9 , pp. 1072-1078
    • Skaper, S.D.1
  • 224
    • 34548140460 scopus 로고    scopus 로고
    • Association between Helicobacter pylori infection and mild cognitive impairment
    • Kountouras J, Tsolaki M, Boziki M, et al. Association between Helicobacter pylori infection and mild cognitive impairment. Eur J Neurol. 2007;14 9:976-982.
    • (2007) Eur J Neurol , vol.14 , Issue.9 , pp. 976-982
    • Kountouras, J.1    Tsolaki, M.2    Boziki, M.3
  • 225
    • 33645826914 scopus 로고    scopus 로고
    • Relationship between Helicobacter pylori infection and Alzheimer disease
    • Kountouras J, Tsolaki M, Gavalas E, et al. Relationship between Helicobacter pylori infection and Alzheimer disease. Neurology. 2006;66 6:938-940.
    • (2006) Neurology , vol.66 , Issue.6 , pp. 938-940
    • Kountouras, J.1    Tsolaki, M.2    Gavalas, E.3
  • 226
    • 84979073211 scopus 로고    scopus 로고
    • Homocysteine, B vitamins, and cognitive impairment
    • Smith AD, Refsum H. Homocysteine, B vitamins, and cognitive impairment. Annu Rev Nutr. 2016;36 1:211-239.
    • (2016) Annu Rev Nutr , vol.36 , Issue.1 , pp. 211-239
    • Smith, A.D.1    Refsum, H.2
  • 227
    • 85003918732 scopus 로고    scopus 로고
    • Endothelial cells microparticle-associated protein disulfide isomerase promotes platelet activation in metabolic syndrome
    • Fan G-Q, Qin R-R, Li Y-H, et al. Endothelial cells microparticle-associated protein disulfide isomerase promotes platelet activation in metabolic syndrome. Oncotarget. 2016;7 50:83231-83240.
    • (2016) Oncotarget , vol.7 , Issue.50 , pp. 83231-83240
    • Fan, G.-Q.1    Qin, R.-R.2    Li, Y.-H.3
  • 228
    • 84995530349 scopus 로고    scopus 로고
    • Homocysteine is a marker for metabolic syndrome and atherosclerosis
    • Sreckovic B, Sreckovic VD, Soldatovic I, et al. Homocysteine is a marker for metabolic syndrome and atherosclerosis. Diabetes Metab Syndr. 2016; 11:179-182.
    • (2016) Diabetes Metab Syndr , vol.11 , pp. 179-182
    • Sreckovic, B.1    Sreckovic, V.D.2    Soldatovic, I.3
  • 229
    • 1642349999 scopus 로고    scopus 로고
    • Induction of apoptosis as a proposed pathophysiological link between glaucoma and Helicobacter pylori infection
    • Kountouras J, Zavos C, Chatzopoulos D. Induction of apoptosis as a proposed pathophysiological link between glaucoma and Helicobacter pylori infection. Med Hypotheses. 2004;62 3:378-381.
    • (2004) Med Hypotheses , vol.62 , Issue.3 , pp. 378-381
    • Kountouras, J.1    Zavos, C.2    Chatzopoulos, D.3
  • 230
    • 0035112368 scopus 로고    scopus 로고
    • Relationship between Helicobacter pylori infection and glaucoma
    • Kountouras J, Mylopoulos N, Boura P, et al. Relationship between Helicobacter pylori infection and glaucoma. Ophthalmology. 2001;108 3:599-604.
    • (2001) Ophthalmology , vol.108 , Issue.3 , pp. 599-604
    • Kountouras, J.1    Mylopoulos, N.2    Boura, P.3
  • 231
    • 84872232547 scopus 로고    scopus 로고
    • Does Helicobacter pylori infection increase incidence of dementia? The Personnes Agées QUID Study
    • Roubaud Baudron C, Letenneur L, Langlais A, et al. Does Helicobacter pylori infection increase incidence of dementia? The Personnes Agées QUID Study. J Am Geriatr Soc. 2013;61 1:74-78.
    • (2013) J Am Geriatr Soc , vol.61 , Issue.1 , pp. 74-78
    • Roubaud Baudron, C.1    Letenneur, L.2    Langlais, A.3
  • 232
  • 233
    • 84920972900 scopus 로고    scopus 로고
    • Interaction between Helicobacter pylori and latent toxoplasmosis and demographic variables on cognitive function in young to middle-aged adults
    • Gale SD, Erickson LD, Brown BL, Hedges DW. Interaction between Helicobacter pylori and latent toxoplasmosis and demographic variables on cognitive function in young to middle-aged adults. PLoS ONE. 2015;10 1:1-18.
    • (2015) PLoS ONE , vol.10 , Issue.1 , pp. 1-18
    • Gale, S.D.1    Erickson, L.D.2    Brown, B.L.3    Hedges, D.W.4
  • 235
    • 0037075257 scopus 로고    scopus 로고
    • Plasma homocysteine as a risk factor for dementia and Alzheimer's disease
    • Seshadri S, Beiser A, Selhub J, et al. Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med. 2002;346 7:476-483.
    • (2002) N Engl J Med , vol.346 , Issue.7 , pp. 476-483
    • Seshadri, S.1    Beiser, A.2    Selhub, J.3
  • 236
    • 76849087664 scopus 로고    scopus 로고
    • Homocysteine levels in chronic gastritis and other conditions: relations to incident cardiovascular disease and dementia
    • Redéen S, Ryberg A, Petersson F, Eriksson O, Nägga K, Borch K. Homocysteine levels in chronic gastritis and other conditions: relations to incident cardiovascular disease and dementia. Dig Dis Sci. 2010;55 2:351-358.
    • (2010) Dig Dis Sci , vol.55 , Issue.2 , pp. 351-358
    • Redéen, S.1    Ryberg, A.2    Petersson, F.3    Eriksson, O.4    Nägga, K.5    Borch, K.6
  • 237
    • 84949960557 scopus 로고    scopus 로고
    • Helicobacter pylori -related vitamin B12 deficiency: a potential contributor in neuropsychiatric disorders
    • Kountouras J, Polyzos SA, Grigoriadis N, Deretzi G. Helicobacter pylori -related vitamin B12 deficiency: a potential contributor in neuropsychiatric disorders. Indian J Psychol Med. 2015;37 4:475-476.
    • (2015) Indian J Psychol Med , vol.37 , Issue.4 , pp. 475-476
    • Kountouras, J.1    Polyzos, S.A.2    Grigoriadis, N.3    Deretzi, G.4
  • 238
    • 81155145970 scopus 로고    scopus 로고
    • Histological presence of Helicobacter pylori bacteria in the trabeculum and iris of patients with primary open-angle glaucoma
    • Zavos C, Kountouras J, Sakkias G, Venizelos I, Deretzi G, Arapoglou S. Histological presence of Helicobacter pylori bacteria in the trabeculum and iris of patients with primary open-angle glaucoma. Ophthalmic Res. 2012;47 3:150-156.
    • (2012) Ophthalmic Res , vol.47 , Issue.3 , pp. 150-156
    • Zavos, C.1    Kountouras, J.2    Sakkias, G.3    Venizelos, I.4    Deretzi, G.5    Arapoglou, S.6
  • 239
    • 84991108604 scopus 로고    scopus 로고
    • Helicobacter pylori -related ApoE 4 polymorphism may be associated with dysphagic symptoms in older adults
    • Kountouras J, Tsolaki F, Tsolaki M, et al. Helicobacter pylori -related ApoE 4 polymorphism may be associated with dysphagic symptoms in older adults. Dis Esophagus Off J Int Soc Dis Esophagus. 2016;29 7:842.
    • (2016) Dis Esophagus Off J Int Soc Dis Esophagus , vol.29 , Issue.7 , pp. 842
    • Kountouras, J.1    Tsolaki, F.2    Tsolaki, M.3
  • 240
    • 80053954876 scopus 로고    scopus 로고
    • The in vivo functions of a histidine-rich protein Hpn in Helicobacter pylori: linking gastric and Alzheimer's diseases together?
    • Ge R, Sun X. The in vivo functions of a histidine-rich protein Hpn in Helicobacter pylori: linking gastric and Alzheimer's diseases together? Med Hypotheses. 2011;77 5:788-790.
    • (2011) Med Hypotheses , vol.77 , Issue.5 , pp. 788-790
    • Ge, R.1    Sun, X.2
  • 241
    • 84941686757 scopus 로고    scopus 로고
    • Is Helicobacter pylori infection a critical risk factor for vascular dementia?
    • Xu Y, Wang Q, Liu Y, Cui R, Zhao Y. Is Helicobacter pylori infection a critical risk factor for vascular dementia? Int J Neurosci. 2016;126 10:899-903.
    • (2016) Int J Neurosci , vol.126 , Issue.10 , pp. 899-903
    • Xu, Y.1    Wang, Q.2    Liu, Y.3    Cui, R.4    Zhao, Y.5
  • 242
    • 84901336546 scopus 로고    scopus 로고
    • Helicobacter pylori filtrate impairs spatial learning and memory in rats and increases β-amyloid by enhancing expression of presenilin-2
    • Wang X-L, Zeng J, Feng J, et al. Helicobacter pylori filtrate impairs spatial learning and memory in rats and increases β-amyloid by enhancing expression of presenilin-2. Front Aging Neurosci. 2014;6 APR:66.
    • (2014) Front Aging Neurosci , vol.6 , Issue.APR , pp. 66
    • Wang, X.-L.1    Zeng, J.2    Feng, J.3
  • 243
    • 84928156543 scopus 로고    scopus 로고
    • An eighteen-month helicobacter infection does not induce amyloid plaques or neuroinflammation in brains of wild type C57BL/6J mice
    • Baudron CR, Chambonnier L, Buissionnière A, et al. An eighteen-month helicobacter infection does not induce amyloid plaques or neuroinflammation in brains of wild type C57BL/6J mice. J Alzheimers Dis. 2015;45 4:1045-1050.
    • (2015) J Alzheimers Dis , vol.45 , Issue.4 , pp. 1045-1050
    • Baudron, C.R.1    Chambonnier, L.2    Buissionnière, A.3
  • 244
    • 79961023266 scopus 로고    scopus 로고
    • The relationship between Helicobacter pylori infection and Alzheimer's disease in Japan
    • Shiota S, Murakami K, Yoshiiwa A, et al. The relationship between Helicobacter pylori infection and Alzheimer's disease in Japan. J Neurol. 2011;258 8:1460-1463.
    • (2011) J Neurol , vol.258 , Issue.8 , pp. 1460-1463
    • Shiota, S.1    Murakami, K.2    Yoshiiwa, A.3
  • 246
    • 84893758242 scopus 로고    scopus 로고
    • Eradication of Helicobacter pylori is associated with the progression of dementia: A population-based study
    • Chang YP, Chiu GF, Kuo FC, et al. Eradication of Helicobacter pylori is associated with the progression of dementia: A population-based study. Gastroenterol Res Pract. 2013;2013:175729.
    • (2013) Gastroenterol Res Pract , vol.2013 , pp. 175729
    • Chang, Y.P.1    Chiu, G.F.2    Kuo, F.C.3
  • 247
    • 84959517874 scopus 로고    scopus 로고
    • Folate and inflammatory markers moderate the association between Helicobacter pylori exposure and cognitive function in US adults
    • Berrett AN, Gale SD, Erickson LD, Brown BL, Hedges DW. Folate and inflammatory markers moderate the association between Helicobacter pylori exposure and cognitive function in US adults. Helicobacter. 2016;21 6:471-480.
    • (2016) Helicobacter , vol.21 , Issue.6 , pp. 471-480
    • Berrett, A.N.1    Gale, S.D.2    Erickson, L.D.3    Brown, B.L.4    Hedges, D.W.5
  • 248
    • 84926350674 scopus 로고    scopus 로고
    • Helicobacter pylori seropositivity's association with markers of iron, 1-carbon metabolism, and antioxidant status among US adults: A structural equations modeling approach
    • Beydoun MA, Dore GA, Canas JA, Beydoun HA, Zonderman AB. Helicobacter pylori seropositivity's association with markers of iron, 1-carbon metabolism, and antioxidant status among US adults: A structural equations modeling approach. PLoS ONE. 2015;10 3:1-16.
    • (2015) PLoS ONE , vol.10 , Issue.3 , pp. 1-16
    • Beydoun, M.A.1    Dore, G.A.2    Canas, J.A.3    Beydoun, H.A.4    Zonderman, A.B.5
  • 249
    • 85027495686 scopus 로고    scopus 로고
    • Novel and effective therapeutic regimens for Helicobacter pylori in an era of increasing antibiotic resistance
    • Hu Y, Zhu Y, Lu N-H. Novel and effective therapeutic regimens for Helicobacter pylori in an era of increasing antibiotic resistance. Front Cell Infect Microbiol. 2017;7:168.
    • (2017) Front Cell Infect Microbiol , vol.7 , pp. 168
    • Hu, Y.1    Zhu, Y.2    Lu, N.-H.3
  • 250
    • 85023751209 scopus 로고    scopus 로고
    • Antibiotic resistance in Helicobacter pylori
    • Alba C, Blanco A, Alarcón T. Antibiotic resistance in Helicobacter pylori. Curr Opin Infect Dis. 2017;30 5:489-497.
    • (2017) Curr Opin Infect Dis , vol.30 , Issue.5 , pp. 489-497
    • Alba, C.1    Blanco, A.2    Alarcón, T.3
  • 251
    • 85031869362 scopus 로고    scopus 로고
    • Primary antibiotic resistance in Helicobacter pylori in the Asia-Pacific region: a systematic review and meta-analysis
    • Kuo Y-T, Liou J-M, El-Omar EM, et al. Primary antibiotic resistance in Helicobacter pylori in the Asia-Pacific region: a systematic review and meta-analysis. Lancet Gastroenterol Hepatol. 2017;2 10:707-715.
    • (2017) Lancet Gastroenterol Hepatol , vol.2 , Issue.10 , pp. 707-715
    • Kuo, Y.-T.1    Liou, J.-M.2    El-Omar, E.M.3
  • 252
    • 84924420679 scopus 로고    scopus 로고
    • Roadmap for elimination of gastric cancer in Korea
    • Graham DY. Roadmap for elimination of gastric cancer in Korea. Korean J Intern Med. 2015;30 2:133-139.
    • (2015) Korean J Intern Med , vol.30 , Issue.2 , pp. 133-139
    • Graham, D.Y.1
  • 253
    • 85029175904 scopus 로고    scopus 로고
    • Comment on “Effect of biofilm formation by clinical isolates of Helicobacter pylori on the efflux-mediated resistance to commonly used antibiotics
    • Kazakos EI, Dorrell N, Polyzos SA, Deretzi G, Kountouras J. Comment on “Effect of biofilm formation by clinical isolates of Helicobacter pylori on the efflux-mediated resistance to commonly used antibiotics”. World J Gastroenterol. 2017;23 33:6194-6196.
    • (2017) World J Gastroenterol , vol.23 , Issue.33 , pp. 6194-6196
    • Kazakos, E.I.1    Dorrell, N.2    Polyzos, S.A.3    Deretzi, G.4    Kountouras, J.5
  • 254
    • 85037727131 scopus 로고    scopus 로고
    • The hypothesis that Helicobacter pylori predisposes to Alzheimer's disease is biologically plausible
    • Felice C, Federico C, Andrea F, et al. The hypothesis that Helicobacter pylori predisposes to Alzheimer's disease is biologically plausible. Sci Rep. 2017;7 1:7817.
    • (2017) Sci Rep , vol.7 , Issue.1 , pp. 7817
    • Felice, C.1    Federico, C.2    Andrea, F.3
  • 255
    • 84861202762 scopus 로고    scopus 로고
    • A genome-wide study reveals rare CNVs exclusive to extreme phenotypes of Alzheimer disease
    • Rovelet-Lecrux A, Legallic S, Wallon D, et al. A genome-wide study reveals rare CNVs exclusive to extreme phenotypes of Alzheimer disease. Eur J Hum Genet. 2012;20 6:613-617.
    • (2012) Eur J Hum Genet , vol.20 , Issue.6 , pp. 613-617
    • Rovelet-Lecrux, A.1    Legallic, S.2    Wallon, D.3


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