Aggravation of Alzheimer's disease due to the COX-2-mediated reciprocal regulation of IL-1β and Aβ between glial and neuron cells

Aging Cell

Volumn 13, Issue 4, 2014, Pages 605-615

  Wang, Pu ^a   Guan, Pei Pei ^a   Wang, Tao ^a   Yu, Xin ^a   Guo, Jian Jun ^a   Wang, Zhan You ^a  

^a NORTHEASTERN UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Cytokines; Gene expression; Neurodegenerative disease; Signal transduction

Indexed keywords

AMYLOID BETA PROTEIN; BETA SECRETASE 1; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOOXYGENASE 2; HEAT SHOCK PROTEIN 70; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTAGLANDIN E; PROSTAGLANDIN E2; PROTEIN KINASE B; TRANSCRIPTION FACTOR RELA; CYCLIC AMP DEPENDENT PROTEIN KINASE; SECRETASE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; ASTROCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE COURSE; DISEASE EXACERBATION; ENZYME SYNTHESIS; GLIA CELL; GLIOBLASTOMA; HUMAN; HUMAN CELL; MICROGLIA; NERVE CELL; NEUROBLASTOMA CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; ENZYMOLOGY; GENETICS; GLIA; METABOLISM; MOUSE; PATHOLOGY; TUMOR CELL LINE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; CELL LINE, TUMOR; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLOOXYGENASE 2; DINOPROSTONE; DISEASE PROGRESSION; HSP70 HEAT-SHOCK PROTEINS; HUMANS; INTERLEUKIN-1BETA; MICE; MODELS, BIOLOGICAL; NEUROGLIA; NEURONS; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84905001803     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12209     Document Type: Article

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