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Volumn 1384, Issue , 2011, Pages 89-96

Tetrandrine attenuates spatial memory impairment and hippocampal neuroinflammation via inhibiting NF-κB activation in a rat model of Alzheimer's disease induced by amyloid-β(1-42)

Author keywords

Alzheimer's disease; Amyloid ; Morris water maze test; Neuroinflammation; NF B; Tetrandrine

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; TETRANDRINE; TUMOR NECROSIS FACTOR ALPHA;

EID: 79953025369     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2011.01.103     Document Type: Article
Times cited : (108)

References (51)
  • 2
    • 0028174061 scopus 로고
    • Function and activation of NF-κB in the immune system
    • P. Baeuerle, and T. Henkel Function and activation of NF-κB in the immune system Annu. Rev. Immunol. 12 1994 141 153
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 141-153
    • Baeuerle, P.1    Henkel, T.2
  • 3
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and i kappa B proteins: New discoveries and insights
    • A.S. Baldwin Jr. The NF-kappa B and I kappa B proteins: new discoveries and insights Annu. Rev. Immunol. 14 1996 649 683
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 649-683
    • Baldwin Jr., A.S.1
  • 4
    • 0032084331 scopus 로고    scopus 로고
    • The NF-κB/Rel family of proteins mediates A β-induced neurotoxicity and glial activation
    • DOI 10.1016/S0169-328X(98)00066-7, PII S0169328X98000667
    • K.R. Bales, Y. Du, R.C. Dodel, G.M. Yan, E. Hamilton-Byrd, and S.M. Paul The NF-κB/Rel family of proteins mediates Aβ-induced neurotoxicity and glial activation Brain Res. Mol. Brain Res. 57 1998 63 72 (Pubitemid 28279561)
    • (1998) Molecular Brain Research , vol.57 , Issue.1 , pp. 63-72
    • Bales, K.R.1    Du, Y.2    Dodel, R.C.3    Yan, G.-M.4    Hamilton-Byrd, E.5    Paul, S.M.6
  • 6
    • 0030869114 scopus 로고    scopus 로고
    • Nuclear translocation of NF-κB in cholinergic neurons of patients with Alzheimer's disease
    • F. Boissiere, S. Hunot, B. Faucheux, C. Duyckaerts, J. Hauw, Y. Agid, and E.C. Hirsch Nuclear translocation of NF- κB in cholinergic neurons of patients with Alzheimer's disease NeuroReport 8 1997 2849 2852 (Pubitemid 27394805)
    • (1997) NeuroReport , vol.8 , Issue.13 , pp. 2849-2852
    • Boissiere, F.1    Hunot, S.2    Faucheux, B.3    Duyckaerts, C.4    Hauw, J.-J.5    Agid, Y.6    Hirsch, E.C.7
  • 7
    • 0030793528 scopus 로고    scopus 로고
    • Activation of nuclear factor-κB by β-amyloid peptides and interferon- γ in murine microglia
    • DOI 10.1016/S0165-5728(97)00054-4, PII S0165572897000544
    • C. Bonaiuto, P.P. McDonald, F. Rossi, and M.A. Cassatella Activation of nuclear factor-kappa B by beta-amyloid peptides and interferon-gamma in murine microglia J. Neuroimmunol. 77 1997 51 56 (Pubitemid 27286376)
    • (1997) Journal of Neuroimmunology , vol.77 , Issue.1 , pp. 51-56
    • Bonaiuto, C.1    McDonald, P.P.2    Rossi, F.3    Cassatella, M.A.4
  • 8
    • 44349140124 scopus 로고    scopus 로고
    • NF-κB-dependent control of BACE1 promoter transactivation by Aβ42
    • V. Buggia-Prevot, J. Sevalle, S. Rossner, and F. Checler NF-κB-dependent control of BACE1 promoter transactivation by Aβ42 J. Biol. Chem. 283 2008 10037 10047
    • (2008) J. Biol. Chem. , vol.283 , pp. 10037-10047
    • Buggia-Prevot, V.1    Sevalle, J.2    Rossner, S.3    Checler, F.4
  • 9
    • 33747036919 scopus 로고    scopus 로고
    • Oxidative stress in Alzheimer's disease brain: New insights from redox proteomics
    • DOI 10.1016/j.ejphar.2006.06.026, PII S0014299906006467
    • D.A. Butterfield, M. Perluigi, and R. Sultana Oxidative stress in Alzheimer's disease brain: new insights from redox proteomics Eur. J. Pharmacol. 545 2006 39 50 (Pubitemid 44215876)
    • (2006) European Journal of Pharmacology , vol.545 , Issue.1 , pp. 39-50
    • Butterfield, D.A.1    Perluigi, M.2    Sultana, R.3
  • 10
    • 33846675520 scopus 로고    scopus 로고
    • NF-ΚB as a therapeutic target in neurodegenerative diseases
    • DOI 10.1517/14728222.11.2.123
    • S. Camandola, and M.P. Mattson NF-kappa B as a therapeutic target in neurodegenerative diseases Expert Opin. Ther. Targets 11 2007 123 132 (Pubitemid 46188809)
    • (2007) Expert Opinion on Therapeutic Targets , vol.11 , Issue.2 , pp. 123-132
    • Camandola, S.1    Mattson, M.P.2
  • 13
    • 0036902141 scopus 로고    scopus 로고
    • Potential role of tetrandrine in cancer therapy
    • Y.J. Chen Potential role of tetrandrine in cancer therapy Acta Pharmacol. Sin. 23 2002 1102 1106
    • (2002) Acta Pharmacol. Sin. , vol.23 , pp. 1102-1106
    • Chen, Y.J.1
  • 15
    • 0033974921 scopus 로고    scopus 로고
    • Attenuation of interleukin-8 production by inhibiting nuclear factor-κB translocation using decoy oligonucleotides
    • DOI 10.1016/S0006-2952(99)00375-5, PII S0006295299003755
    • J.A. Cooper Jr., J.M. Parks, R. Carcelen, S.S. Kahlon, M. Sheffield, and R. Culbreth Attenuation of interleukin-8 production by inhibiting nuclear factor-κB translocation using decoy oligonucleotides Biochem. Pharmacol. 59 2000 605 613 (Pubitemid 30085441)
    • (2000) Biochemical Pharmacology , vol.59 , Issue.6 , pp. 605-613
    • Cooper Jr., J.A.D.1    Parks, J.M.2    Carcelen, R.3    Kahlon, S.S.4    Sheffield, M.5    Culbreth, R.6
  • 17
    • 0028972845 scopus 로고
    • Mechanistic aspects of NF-κB regulation: The emerging role of phosphorylation and proteolysis
    • T. Finco, and A.S. Baldwin Jr. Mechanistic aspects of NF-κB regulation: the emerging role of phosphorylation and proteolysis Immunity 3 1995 263 272
    • (1995) Immunity , vol.3 , pp. 263-272
    • Finco, T.1    Baldwin Jr., A.S.2
  • 18
    • 21844439776 scopus 로고    scopus 로고
    • Sulfasalazine inhibits activation of nuclear factor-κB in patients with ulcerative colitis
    • H.T. Gan, Y.Q. Chen, and Q. Ouyan Sulfasalazine inhibits activation of nuclear factor-κB in patients with ulcerative colitis J. Gastroenterol. Hepatol. 20 2005 1016 1024
    • (2005) J. Gastroenterol. Hepatol. , vol.20 , pp. 1016-1024
    • Gan, H.T.1    Chen, Y.Q.2    Ouyan, Q.3
  • 19
    • 34548316575 scopus 로고    scopus 로고
    • Deletion of tumor necrosis factor death receptor inhibits amyloid β generation and prevents learning and memory deficits in Alzheimer's mice
    • DOI 10.1083/jcb.200705042
    • P. He, Z. Zhong, K. Lindholm, L. Berning, W. Lee, C. Lemere, M. Staufenbiel, R. Li, and Y. Shen Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice J. Cell Biol. 178 2007 829 841 (Pubitemid 47347367)
    • (2007) Journal of Cell Biology , vol.178 , Issue.5 , pp. 829-841
    • He, P.1    Zhong, Z.2    Lindholm, K.3    Berning, L.4    Lee, W.5    Lemere, C.6    Staufenbiel, M.7    Li, R.8    Shen, Y.9
  • 20
    • 10844264170 scopus 로고    scopus 로고
    • Plant alkaloid tetrandrine downregulates IκBα kinases-IκBα-NF-κB signaling pathway in human peripheral blood T cell
    • DOI 10.1038/sj.bjp.0706000
    • L.J. Ho, T.Y. Juan, P. Chao, W.L. Wu, D.M. Chang, S.Y. Chang, and J.H. Lai Plant alkaloid tetrandrine downregulates IkappaBalpha kinases-IkappaBalpha- NF-kappaB signaling pathway in human peripheral blood T cell Br. J. Pharmacol. 143 2004 919 927 (Pubitemid 39664851)
    • (2004) British Journal of Pharmacology , vol.143 , Issue.7 , pp. 919-927
    • Ho, L.-J.1    Juan, T.-Y.2    Chao, P.3    Wu, W.-L.4    Chang, D.-M.5    Chang, S.-Y.6    Lai, J.-H.7
  • 22
    • 0030842316 scopus 로고    scopus 로고
    • Vasodilating and hypotensive effects of fangchinoline and tetrandrine on the rat aorta and the stroke-prone spontaneously hypertensive rat
    • H.S. Kim, Y.H. Zhang, K.W. Oh, and H.Y. Ahn Vasodilating and hypotensive effects of fangchinoline and tetrandrine on the rat aorta and the stroke-prone spontaneously hypertensive rat J. Ethnopharmacol. 58 1997 117 123
    • (1997) J. Ethnopharmacol. , vol.58 , pp. 117-123
    • Kim, H.S.1    Zhang, Y.H.2    Oh, K.W.3    Ahn, H.Y.4
  • 23
    • 0036902138 scopus 로고    scopus 로고
    • Tetrandrine and related bis-benzylisoquinoline alkaloids from medicinal herbs: Cardiovascular effects and mechanisms of action
    • C.Y. Kwan, and F.I. Achike Tetrandrine and related bisbenzylisoquinoline alkaloids from medicinal herbs: cardiovascular effects and mechanisms of action Acta Pharmacol. Sin. 23 2002 1057 1068 (Pubitemid 35470328)
    • (2002) Acta Pharmacologica Sinica , vol.23 , Issue.12 , pp. 1057-1068
    • Kwan, C.-Y.1    Achike, F.I.2
  • 24
    • 0036901923 scopus 로고    scopus 로고
    • Immunomodulatory effects and mechanisms of plant alkaloid tetrandrine in autoimmune diseases
    • J.H. Lai Immunomodulatory effects and mechanisms of plant alkaloid tetrandrine in autoimmune diseases Acta Pharmacol. Sin. 23 2002 1093 1101
    • (2002) Acta Pharmacol. Sin. , vol.23 , pp. 1093-1101
    • Lai, J.H.1
  • 25
    • 12244263536 scopus 로고    scopus 로고
    • Effects of tetrandrine and QYT on ICAM-1 and SOD gene expression in pancreas and liver of rats with acute pancreatitis
    • Y.Y. Li, X.L. Li, C.X. Yang, H. Zhong, H. Yao, and L. Zhu Effects of tetrandrine and QYT on ICAM-1 and SOD gene expression in pancreas and liver of rats with acute pancreatitis World J. Gastroenterol. 9 2003 155 159 (Pubitemid 36131300)
    • (2003) World Journal of Gastroenterology , vol.9 , Issue.1 , pp. 155-159
    • Li, Y.-Y.1    Li, X.-L.2    Yang, C.-X.3    Zhong, H.4    Yao, H.5    Zhu, L.6
  • 26
    • 46749125681 scopus 로고    scopus 로고
    • Tetrandrine suppresses LPS-induced astrocyte activation via modulating IKKs-IkappaBalpha-NF-kappaB signaling pathway
    • S.T. Lin, Y. Wang, Y. Xue, D.C. Feng, Y. Xu, and L.Y. Xu Tetrandrine suppresses LPS-induced astrocyte activation via modulating IKKs-IkappaBalpha-NF- kappaB signaling pathway Mol. Cell. Biochem. 315 2008 41 49
    • (2008) Mol. Cell. Biochem. , vol.315 , pp. 41-49
    • Lin, S.T.1    Wang, Y.2    Xue, Y.3    Feng, D.C.4    Xu, Y.5    Xu, L.Y.6
  • 27
    • 34250615440 scopus 로고    scopus 로고
    • NP031112, a Thiadiazolidinone compound, prevents inflammation and neurodegeneration under excitotoxic conditions: Potential therapeutic role in brain disorders
    • DOI 10.1523/JNEUROSCI.1004-07.2007
    • R. Luna-Medina, M. Cortes-Canteli, S. Sanchez-Galiano, J.A. Morales-Garcia, A. Martinez, A. Santos, and A. Perez-Castillo NP031112, a thiadiazolidinone compound, prevents inflammation and neurodegeneration under excitotoxic conditions: potential therapeutic role in brain disorders J. Neurosci. 27 2007 5766 5776 (Pubitemid 350021090)
    • (2007) Journal of Neuroscience , vol.27 , Issue.21 , pp. 5766-5776
    • Luna-Medina, R.1    Cortes-Canteli, M.2    Sanchez-Galiano, S.3    Morales-Garcia, J.A.4    Martinez, A.5    Santos, A.6    Perez-Castillo, A.7
  • 28
    • 0034746288 scopus 로고    scopus 로고
    • NF-κB in neuronal plasticity and neurodegenerative disorders
    • M.P. Mattson, and S. Camandola NF-κB in neuronal plasticity and neurodegenerative disorders J. Clin. Invest. 107 2001 247 254 (Pubitemid 32162153)
    • (2001) Journal of Clinical Investigation , vol.107 , Issue.3 , pp. 247-254
    • Mattson, M.P.1    Camandola, S.2
  • 30
    • 0021173996 scopus 로고
    • Development of a water maze procedure for studying spatial learning in the rat
    • R.G. Morris Development of a water maze procedure for studying spatial learning in the rat J. Neurosci. Meth. 11 1984 47 60
    • (1984) J. Neurosci. Meth. , vol.11 , pp. 47-60
    • Morris, R.G.1
  • 32
    • 0031172065 scopus 로고    scopus 로고
    • NF-κB: A crucial transcription factor for glial and neuronal cell function
    • DOI 10.1016/S0166-2236(96)01035-1
    • L.A. O'Neill, and C. Kaltschmidt NF-kappa B: a crucial transcription factor for glial and neuronal cell function Trends Neurosci. 20 1997 252 258 (Pubitemid 27261456)
    • (1997) Trends in Neurosciences , vol.20 , Issue.6 , pp. 252-258
    • O'Neill, L.A.J.1    Kaltschmidt, C.2
  • 34
    • 0036905327 scopus 로고    scopus 로고
    • Effects of tetrandrine on cardiac and vascular remodeling
    • M.R. Rao Effects of tetrandrine on cardiac and vascular remodeling Acta Pharmacol. Sin. 23 2002 1075 1085
    • (2002) Acta Pharmacol. Sin. , vol.23 , pp. 1075-1085
    • Rao, M.R.1
  • 35
    • 49249118742 scopus 로고    scopus 로고
    • Neurotoxic effect of oligomeric and fibrillar species of amyloid-beat peptide 1-42: Involvement of endoplasmic reticulum calcium release in oligomer-induced cell death
    • R. Resende, E. Ferreio, C. Pereira, and C. Resende de oliveira Neurotoxic effect of oligomeric and fibrillar species of amyloid-beat peptide 1-42: involvement of endoplasmic reticulum calcium release in oligomer-induced cell death Neuroscience 155 2008 725 737
    • (2008) Neuroscience , vol.155 , pp. 725-737
    • Resende, R.1    Ferreio, E.2    Pereira, C.3    Resende De Oliveira, C.4
  • 36
    • 0027637015 scopus 로고
    • Evaluation of the novel anti-inflammatory agent tetrandrine as a pulpotomy medicament in a canine model
    • W.K. Seow, and Y.H. Thong Evaluation of the novel anti-inflammatory agent tetrandrine as a pulpotomy medicament in a canine model Pediatr. Dent. 15 1993 260 266
    • (1993) Pediatr. Dent. , vol.15 , pp. 260-266
    • Seow, W.K.1    Thong, Y.H.2
  • 37
    • 0032705352 scopus 로고    scopus 로고
    • Tetrandrine ameliorates ischaemia-reperfusion injury of rat myocardium through inhibition of neutrophil priming and activation
    • Y.C. Shen, C.F. Chen, and Y.J. Sung Tetrandrine ameliorates ischaemia-reperfusion injury of rat myocardium through inhibition of neutrophil priming and activation Br. J. Pharmacol. 128 1999 1593 1601
    • (1999) Br. J. Pharmacol. , vol.128 , pp. 1593-1601
    • Shen, Y.C.1    Chen, C.F.2    Sung, Y.J.3
  • 38
    • 0034757747 scopus 로고    scopus 로고
    • Anti-inflammatory effects of the partially purified extract of radix Stephania tetrandra: Comparative studies of its active principles tetrandrine and fangchinoline on human polymorphonuclear leukocyte functions
    • Y.C. Shen, C.J. Chou, W.F. Chiou, and C.F. Chen Anti-inflammatory effects of the partially purified extract of radix Stephania tetrandra: comparative studies of its active principles tetrandrine and fangchinoline on human polymorphonuclear leukocyte functions Mol. Pharmacol. 60 2001 1083 1090
    • (2001) Mol. Pharmacol. , vol.60 , pp. 1083-1090
    • Shen, Y.C.1    Chou, C.J.2    Chiou, W.F.3    Chen, C.F.4
  • 40
    • 35348922970 scopus 로고    scopus 로고
    • Ginkgo biloba extract EGb 761 attenuates hippocampal neuronal loss and cognitive dysfunction resulting from chronic restraint stress in ovariectomized rats
    • DOI 10.1016/j.neuroscience.2007.07.042, PII S0306452207010093
    • K. Takuma, Y. Hoshina, S. Arai, Y. Himeno, A. Matsuo, Y. Funatsu, Y. Kitahara, D. Ibi, M. Hayase, H. Kamei, H. Mizoguchi, T. Nagai, K. Koike, M. Inoue, and K. Yamada Ginkgo biloba extract EGb 761 attenuates hippocampal neuronal loss and cognitive dysfunction resulting from chronic restraint stress in ovariectomized rats Neuroscience 149 2007 256 262 (Pubitemid 47576550)
    • (2007) Neuroscience , vol.149 , Issue.2 , pp. 256-262
    • Takuma, K.1    Hoshina, Y.2    Arai, S.3    Himeno, Y.4    Matsuo, A.5    Funatsu, Y.6    Kitahara, Y.7    Ibi, D.8    Hayase, M.9    Kamei, H.10    Mizoguchi, H.11    Nagai, T.12    Koike, K.13    Inoue, M.14    Yamada, K.15
  • 42
    • 44449155518 scopus 로고    scopus 로고
    • The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection
    • T.A. Tran, M.K. McCoy, M.B. Sporn, and M.G. Tansey The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection J. Neuroinflammation 5 2008 14
    • (2008) J. Neuroinflammation , vol.5 , pp. 14
    • Tran, T.A.1    McCoy, M.K.2    Sporn, M.B.3    Tansey, M.G.4
  • 45
    • 1342306776 scopus 로고    scopus 로고
    • Herbal alkaloid tetrandrine: From an ion channel blocker to inhibitor of tumor proliferation
    • DOI 10.1016/j.tips.2004.01.009
    • G. Wang, J.R. Lemos, and C. Iadecola Herbal alkaloid tetrandrine: from an ion channel blocker to inhibitor of tumor proliferation Trends Pharmacol. Sci. 25 2004 120 123 (Pubitemid 38264500)
    • (2004) Trends in Pharmacological Sciences , vol.25 , Issue.3 , pp. 120-123
    • Wang, G.1    Lemos, J.R.2    Iadecola, C.3
  • 46
    • 33846054528 scopus 로고    scopus 로고
    • Tetrandrine inhibits proinflammatory cytokines, iNOS and COX-2 expression in human monocytic cells
    • S.J. Wu, and L.T. Ng Tetrandrine inhibits proinflammatory cytokines, iNOS and COX-2 expression in human monocytic cells Biol. Pharm. Bull. 30 2007 59 62
    • (2007) Biol. Pharm. Bull. , vol.30 , pp. 59-62
    • Wu, S.J.1    Ng, L.T.2
  • 47
    • 0036905824 scopus 로고    scopus 로고
    • Pharmacological actions of tetrandrine in inflammatory pulmonary diseases
    • Q.M. Xie, H.F. Tang, J.Q. Chen, and R.L. Bian Pharmacological actions of tetrandrine in inflammatory pulmonary diseases Acta Pharmacol. Sin. 23 2002 1107 1113
    • (2002) Acta Pharmacol. Sin. , vol.23 , pp. 1107-1113
    • Xie, Q.M.1    Tang, H.F.2    Chen, J.Q.3    Bian, R.L.4
  • 48
    • 38749147302 scopus 로고    scopus 로고
    • Tetrandrine suppresses lipopolysaccharide-induced microglial activation by inhibiting NF-κB pathway
    • DOI 10.1111/j.1745-7254.2008.00734.x
    • Y. Xue, Y. Wang, D.C. Feng, B.G. Xiao, and L.Y. Xu Tetrandrine suppresses lipopolysaccharide-induced microglial activation by inhibiting NF-kappaB pathway Acta Pharmacol. Sin. 29 2008 245 251 (Pubitemid 351178424)
    • (2008) Acta Pharmacologica Sinica , vol.29 , Issue.2 , pp. 245-251
    • Xue, Y.1    Wang, Y.2    Feng, D.-C.3    Xiao, B.-G.4    Xu, L.-Y.5
  • 50
    • 34447503656 scopus 로고    scopus 로고
    • Quetiapine attenuates spatial memory impairment and hippocampal neurodegeneration induced by bilateral common carotid artery occlusion in mice
    • DOI 10.1016/j.lfs.2007.05.020, PII S0024320507004158
    • B. Yan, X. Bi, J. He, Y. Zhang, S. Thakur, H. Xu, A. Gendron, J. Kong, and X.M. Li Quetiapine attenuates spatial memory impairment and hippocampal neurodegeneration induced by bilateral common carotid artery occlusion in mice Life Sci. 81 2007 353 361 (Pubitemid 47082443)
    • (2007) Life Sciences , vol.81 , Issue.5 , pp. 353-361
    • Yan, B.1    Bi, X.2    He, J.3    Zhang, Y.4    Thakur, S.5    Xu, H.6    Gendron, A.7    Kong, J.8    Li, X.-M.9
  • 51
    • 33748598226 scopus 로고    scopus 로고
    • Effect of Tetrandrine on LPS-induced NF-κB activation in isolated pancreatic acinar cells of rat
    • H. Zhang, Y.Y. Li, and X.Z. Wu Effect of tetrandrine on LPS induced NF-kappaB activation in isolated pancreatic acinar cells of rat World J. Gastroenterol. 12 2006 4232 4236 (Pubitemid 44376910)
    • (2006) World Journal of Gastroenterology , vol.12 , Issue.26 , pp. 4232-4236
    • Zhang, H.1    Li, Y.-Y.2    Wu, X.-Z.3


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