The TNF-α/NF-κB signaling pathway has a key role in methamphetamine-induced blood-brain barrier dysfunction

Journal of Cerebral Blood Flow and Metabolism

Volumn 35, Issue 8, 2015, Pages 1260-1271

  Coelho Santos, Vanessa ^a,b   Leitão, Ricardo A ^a,b   Cardoso, Filipa L ^c   Palmela, Inês ^c   Rito, Manuel ^d   Barbosa, Marcos ^d,e   Brito, Maria A ^c   Fontes Ribeiro, Carlos A ^a,b   Silva, Ana P ^a,b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF LISBON   (Portugal)

^d CENTRO HOSPITALAR E UNIVERSITÁRIO DE COIMBRA   (Portugal)

^e UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

astrocytes; blood brain barrier; methamphetamine; nuclear factor kappa B; tumor necrosis factor alpha

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; METHAMPHETAMINE; TUMOR NECROSIS FACTOR ALPHA; CENTRAL STIMULANT AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; ASTROCYTOSIS; BLOOD BRAIN BARRIER; BRAIN CAPILLARY ENDOTHELIAL CELL; CELL TRANSPORT; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EXPOSURE; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; METHAMPHETAMINE DEPENDENCE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; ANIMAL; DRUG EFFECTS; METABOLISM; PATHOLOGY; TRANSPORT AT THE CELLULAR LEVEL; WISTAR RAT;

ANIMALS; ASTROCYTES; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; CENTRAL NERVOUS SYSTEM STIMULANTS; ENDOTHELIAL CELLS; METHAMPHETAMINE; NF-KAPPA B; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84938747863     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2015.59     Document Type: Article

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