Astrocytes play a key role in EAE pathophysiology by orchestrating in the CNS the inflammatory response of resident and peripheral immune cells and by suppressing remyelination

GLIA

Volumn 62, Issue 3, 2014, Pages 452-467

  Brambilla, Roberta ^a   Morton, Paul D ^a   Ashbaugh, Jessica Jopek ^a   Karmally, Shaffiat ^a   Lambertsen, Kate Lykke ^b   Bethea, John R ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Autoimmunity; Neurodegeneration; Neuroinflammation; NF KB

Indexed keywords

GAMMA INTERFERON; GLIAL FIBRILLARY ACIDIC PROTEIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 17; MYELIN; TUMOR NECROSIS FACTOR; CLAUDIN 5; CYTOKINE; I KAPPA B; IMMUNOGLOBULIN G; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN (35-55); NF-KAPPAB INHIBITOR ALPHA; PEPTIDE FRAGMENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; CELL MOTILITY; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ELECTRON MICROSCOPY; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; FEMALE; GENE EXPRESSION; IMMUNOCOMPETENT CELL; LYMPHOCYTIC INFILTRATION; MALE; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; REDUCTION; REMYELINIZATION; SPINAL CORD; T LYMPHOCYTE; TISSUE PRESERVATION; WILD TYPE; ANIMAL; CENTRAL NERVOUS SYSTEM; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INFLAMMATION; LEUKOCYTE; METABOLISM; MYELIN SHEATH; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; TOXICITY; TRANSGENIC MOUSE; ULTRASTRUCTURE;

ANIMALS; ASTROCYTES; CENTRAL NERVOUS SYSTEM; CLAUDIN-5; CYTOKINES; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GENE EXPRESSION REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; I-KAPPA B PROTEINS; IMMUNOGLOBULIN G; INFLAMMATION; LEUKOCYTES; MICE; MICE, TRANSGENIC; MICROSCOPY, ELECTRON; MYELIN SHEATH; MYELIN-OLIGODENDROCYTE GLYCOPROTEIN; PEPTIDE FRAGMENTS; SPINAL CORD; T-LYMPHOCYTES;

EID: 84892503390     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22616     Document Type: Article

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