Cu(II) enhances the effect of Alzheimer's amyloid-β peptide on microglial activation

Journal of Neuroinflammation

Volumn 12, Issue 1, 2015, Pages

  Yu, Fengxiang ^a   Gong, Ping ^a   Hu, Zhuqin ^a   Qiu, Yu ^a   Cui, Yongyao ^a   Gao, Xiaoling ^a   Chen, Hongzhuan ^a   Li, Juan ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Aggregation; Cu(II) Ab complex; Microglia; NF B; Nitric oxide; Reactive oxygen species; Tumor necrosis factor a

Indexed keywords

ACETYLCYSTEINE; AMYLOID BETA PROTEIN; CUPRIC ION; HYDROGEN PEROXIDE; I KAPPA B; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA; COPPER; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SCAVENGER; TUMOR NECROSIS FACTOR;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CELL ACTIVATION; CELL DAMAGE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; INCUBATION TIME; MICROGLIA; MOUSE; NEUROTOXICITY; NEWBORN; NONHUMAN; PROTEIN ANALYSIS; PROTEIN SECRETION; PROTEIN SYNTHESIS; RAT; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; DRUG EFFECTS; HUMAN; MACROPHAGE ACTIVATION; METABOLISM; NERVE CELL;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; CELL LINE; COPPER; FREE RADICAL SCAVENGERS; HUMANS; HYDROGEN PEROXIDE; MACROPHAGE ACTIVATION; MICE; MICROGLIA; NADPH OXIDASE; NEURONS; NF-KAPPA B; NITRIC OXIDE; SUPEROXIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84934278495     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-015-0343-3     Document Type: Article

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