Inflammatory responses following Chlamydia pneumoniae infection of glial cells

European Journal of Neuroscience

Volumn 25, Issue 3, 2007, Pages 753-760

  Boelen, E ^a,b   Steinbusch, H W M ^b   Pronk, I ^c   Grauls, G ^a   Rennert, P ^d   Bailly, V ^d   Bruggeman, C A ^a   Stassen, F R M ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d BIOGEN   (United States)

Author keywords

Bacteria; Cytokines; Glia; In vitro; Mouse; Neurodegeneration

Indexed keywords

CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTRALIZING ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; ARTICLE; ASTROCYTE; BACTERIAL INFECTION; CELL DEATH; CHLAMYDOPHILA PNEUMONIAE; CONTROLLED STUDY; GLIA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; MICROGLIA; MOUSE; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; SUPERNATANT;

ANIMALS; ANTIBODIES; APOPTOSIS; ASTROCYTES; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CHLAMYDOPHILA INFECTIONS; CHLAMYDOPHILA PNEUMONIAE; HUMANS; INTERLEUKIN-6; LIVER NEOPLASMS; MICROGLIA; MURIDAE; NECROSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33847009066     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2007.05339.x     Document Type: Article

References (51)

1. Akiyama, H., Barger, S., Barnum, S., Bradt, B., Bauer, J., Cole, G.M., Cooper, N.R., Eikelenboom, P., Emmerling, M., Fiebich, B.L. et al. (2000) Inflammation and Alzheimer's disease. Neurobiol. Aging, 21, 383-421.
2. Balin, B.J. & Appelt, D.M. (2001) Role of infection in Alzheimer's disease. J. Am. Osteopath. Assoc., 101 (12 Suppl.) Part 1, S1-S6.
3. Balin, B.J., Gerard, H.C., Arking, E.J., Appelt, D.M., Branigan, P.J., Abrams, J.T., Whittum-Hudson, J.A. & Hudson, A.P. (1998) Identification and localization of Chlamydia pneumoniae in the Alzheimer's brain. Med. Microbiol. Immunol. (Berl.), 187, 23-42.
4. Blasi, E., Barluzzi, R., Bocchini, V., Mazzolla, R. & Bistoni, F. (1990) Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus. J. Neuroimmunol., 27, 229-237.
5. Boelen, E., Steinbusch, H.W., van der Ven, A.J., Grauls, G., Bruggeman, C.A. & Stassen, F.R. (in press) Chlamydia pneumoniae infection of brain cells: An in vitro study. Neurobiol. Aging, in press.
6. Bos, M.P. & Tommassen, J. (2004) Biogenesis of the Gram-negative bacterial outer membrane. Curr. Opin. Microbiol., 7, 610-616.
7. Bowman, C.C., Rasley, A., Tranguch, S.L. & Marriott, I. (2003) Cultured astrocytes express toll-like receptors for bacterial products. Glia, 43, 281-291.
8. Bruunsgaard, H., Ostergaard, L., Andersen-Ranberg, K., Jeune, B. & Pedersen, B.K. (2002) Proinflammatory cytokines, antibodies to Chlamydia pneumoniae and age-associated diseases in Danish centenarians: is there a link? Scand. J. Infect. Dis., 34, 493-499.
9. Bsibsi, M., Ravid, R., Gveric, D. & van Noort, J.M. (2002) Broad expression of Toll-like receptors in the human central nervous system. J. Neuropathol. Exp. Neurol., 61, 1013-1021.
10. Chung, I.Y. & Benveniste, E.N. (1990) Tumor necrosis factor-alpha production by astrocytes. Induction by lipopolysaccharide, IFN-gamma, and IL-1 beta. J. Immunol., 144, 2999-3007.
11. Cinque, P., Vago, L., Mengozzi, M., Torri, V., Ceresa, D., Vicenzi, E., Transidico, P., Vagani, A., Sozzani, S., Mantovani, A., Lazzarin, A. & Poli, G. (1998) Elevated cerebrospinal fluid levels of monocyte chemotactic protein-1 correlate with HIV-1 encephalitis and local viral replication. Aids, 12, 1327-1332.
12. Dobson, C.B. & Itzhaki, R.F. (1999) Herpes simplex virus type 1 and Alzheimer's disease. Neurobiol. Aging, 20, 457-465.
13. Epstein, L.G. & Gendelman, H.E. (1993) Human immunodeficiency virus type 1 infection of the nervous system: pathogenetic mechanisms. Ann. Neurol., 33, 429-436.
14. Ezzahiri, R., Stassen, F.R., Kurvers, H.A., van Pul, M.M., Kitslaar, P.J. & Bruggeman, C.A. (2003) Chlamydia pneumoniae infection induces an unstable atherosclerotic plaque phenotype in LDL-receptor, ApoE double knockout mice. Eur. J. Vasc. Endovasc. Surg., 26, 88-95.
15. Farina, C., Krumbholz, M., Giese, T., Hartmann, G., Aloisi, F. & Meinl, E. (2005) Preferential expression and function of Toll-like receptor 3 in human astrocytes. J. Neuroimmunol., 159, 12-19.
16. Gieffers, J., Reusche, E., Solbach, W. & Maass, M. (2000) Failure to detect Chlamydia pneumoniae in brain sections of Alzheimer's disease patients. J. Clin. Microbiol., 38, 881-882.
17. Grayston, J.T., Campbell, L.A., Kuo, C.C., Mordhorst, C.H., Saikku, P., Thom, D.H. & Wang, S.P. (1990) A new respiratory tract pathogen: Chlamydia pneumoniae strain TWAR. J. Infect. Dis., 161, 618-625.
18. Grayston, J.T., Aldous, M.B., Easton, A., Wang, S.P., Kuo, C.C., Campbell, L.A. & Altman, J. (1993) Evidence that Chlamydia pneumoniae causes pneumonia and bronchitis. J. Infect. Dis., 168, 1231-1235.
19. Hald, A. & Lotharius, J. (2005) Oxidative stress and inflammation in Parkinson's disease: is there a causal link? Exp. Neurol., 193, 279-290.
20. Hemling, N., Roytta, M., Rinne, J., Pollanen, P., Broberg, E., Tapio, V., Vahlberg, T. & Hukkanen, V. (2003) Herpesviruses in brains in Alzheimer's and Parkinson's diseases. Ann. Neurol., 54, 267-271.
21. Kolson, D.L. & Gonzalez-Scarano, F. (2000) HIV and HIV dementia. J. Clin. Invest., 106, 11-13.
22. Kuo, C.C. & Grayston, J.T. (1990) A sensitive cell line, HL cells, for isolation and propagation of Chlamydia pneumoniae strain TWAR. J. Infect. Dis., 162, 755-758.
23. Kuo, C.C., Grayston, J.T., Campbell, L.A., Goo, Y.A., Wissler, R.W. & Benditt, E.P. (1995a) Chlamydia pneumoniae (TWAR) in coronary arteries of young adults (15-34 years old). Proc. Natl Acad. Sci. U.S.A., 92, 6911-6914.
24. Kuo, C.C., Jackson, L.A., Campbell, L.A. & Grayston, J.T. (1995b) Chlamydia pneumoniae (TWAR). Clin. Microbiol. Rev., 8, 451-461.
25. Laflamme, N. & Rivest, S. (2001) Toll-like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components. Faseb J., 15, 155-163.
26. Lehnardt, S., Lachance, C., Patrizi, S., Lefebvre, S., Follett, P.L., Jensen, F.E., Rosenberg, P.A., Volpe, J.J. & Vartanian, T. (2002) The toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNS. J. Neurosci., 22, 2478-2486.
27. Lin, W.R., Wozniak, M.A., Wilcock, G.K. & Itzhaki, R.F. (2002) Cytomegalovirus is present in a very high proportion of brains from vascular dementia patients. Neurobiol. Dis., 9, 82-87.
28. Little, C.S., Hammond, C.J., MacIntyre, A., Balin, B.J. & Appelt, D.M. (2004) Chlamydia pneumoniae induces Alzheimer-like amyloid plaques in brains of BALB/c mice. Neurobiol. Aging, 25, 419-429.
29. Little, C.S., Bowe, A., Lin, R., Litsky, J., Fogel, R.M., Balin, B.J. & Fresa-Dillon, K.L. (2005) Age alterations in extent and severity of experimental intranasal infection with Chlamydophila pneumoniae in BALB/c mice. Infect. Immun., 73, 1723-1734.
30. Luterman, J.D., Haroutunian, V., Yemul, S., Ho, L., Purohit, D., Aisen, P.S., Mohs, R. & Pasinetti, G.M. (2000) Cytokine gene expression as a function of the clinical progression of Alzheimer disease dementia. Arch. Neurol., 57, 1153-1160.
31. Mazzini, G., Ferrari, C. & Erba, E. (2003) Dual excitation multi- fluorescence flow cytometry for detailed analyses of viability and apoptotic cell transition. Eur. J. Histochem., 47, 289-298.
32. Naiki, Y., Michelsen, K.S., Schroder, N.W., Alsabeh, R., Slepenkin, A., Zhang, W., Chen, S., Wei, B., Bulut, Y., Wong, M.H., Peterson, E.M. & Arditi, M. (2005) MyD88 is pivotal for the early inflammatory response and subsequent bacterial clearance and survival in a mouse model of Chlamydia pneumoniae pneumonia. J. Biol. Chem., 280, 29 242-29 249.
33. Nakamura, Y., Si, Q.S. & Kataoka, K. (1999) Lipopolysaccharide- induced microglial activation in culture: temporal profiles of morphological change and release of cytokines and nitric oxide. Neurosci. Res., 35, 95-100.
34. Nochlin, D., Shaw, C.M., Campbell, L.A. & Kuo, C.C. (1999) Failure to detect Chlamydia pneumoniae in brain tissues of Alzheimer's disease. Neurology, 53, 1888.
35. Perry, V.H. (2004) The influence of systemic inflammation on inflammation in the brain: implications for chronic neurodegenerative disease. Brain Behav. Immun., 18, 407-413.
36. Pulliam, L., Herndier, B.G., Tang, N.M. & McGrath, M.S. (1991) Human immunodeficiency virus-infected macrophages produce soluble factors that cause histological and neurochemical alterations in cultured human brains. J. Clin. Invest., 87, 503-512.
37. Quinn, T.C. & Gaydos, C.A. (1999) In vitro infection and pathogenesis of Chlamydia pneumoniae in endovascular cells. Am. Heart J., 138, S507-S511.
38. Redecke, V., Dalhoff, K., Bohnet, S., Braun, J. & Maass, M. (1998) Interaction of Chlamydia pneumoniae and human alveolar macrophages: infection and inflammatory response. Am. J. Respir. Cell Mol. Biol., 19, 721-727.
39. Reitsma, P.H. & Rosendaal, F.R. (2004) Activation of innate immunity in patients with venous thrombosis: the Leiden Thrombophilia Study. J. Thromb. Haemost., 2, 619-622.
40. Remarque, E.J., Bollen, E.L., Weverling-Rijnsburger, A.W., Laterveer, J.C., Blauw, G.J. & Westendorp, R.G. (2001) Patients with Alzheimer's disease display a pro-inflammatory phenotype. Exp. Gerontol., 36, 171-176.
41. Ring, R.H. & Lyons, J.M. (2000) Failure to detect Chlamydia pneumoniae in the late-onset Alzheimer's brain. J. Clin. Microbiol., 38, 2591-2594.
42. Roblin, P.M., Dumornay, W. & Hammerschlag, M.R. (1992) Use of HEp-2 cells for improved isolation and passage of Chlamydia pneumoniae. J. Clin. Microbiol., 30, 1968-1971.
43. Rothfuchs, A.G., Gigliotti, D., Palmblad, K., Andersson, U., Wigzell, H. & Rottenberg, M.E. (2001) IFN-alpha beta-dependent, IFN-gamma secretion by bone marrow-derived macrophages controls an intracellular bacterial infection. J. Immunol., 167, 6453-6461.
44. Stratton, C.W. & Sriram, S. (2003) Association of Chlamydia pneumoniae with central nervous system disease. Microbes Infect., 5, 1249-1253.
45. Swanson, R.A., Liu, J., Miller, J.W., Rothstein, J.D., Farrell, K., Stein, B.A. & Longuemare, M.C. (1997) Neuronal regulation of glutamate transporter subtype expression in astrocytes. J. Neurosci., 17, 932-940.
46. Takeshita, S., Takeshita, F., Haddad, D.E., Janabi, N. & Klinman, D.M. (2001) Activation of microglia and astrocytes by CpG oligodeoxynucleotides. Neuroreport, 12, 3029-3032.
47. Taylor, G.S., Vipond, I.B., Paul, I.D., Matthews, S., Wilcock, G.K. & Caul, E.O. (2002) Failure to correlate C. pneumoniae with late onset Alzheimer's disease. Neurology, 59, 142-143.
48. Weinberger, M. (2004) Respiratory infections and asthma: current treatment strategies. Drug Discov. Today, 9, 831-837.
49. Weiner, H.L. & Selkoe, D.J. (2002) Inflammation and therapeutic vaccination in CNS diseases. Nature, 420, 879-884.
50. Wucherpfennig, K.W. (2002) Infectious triggers for inflammatory neurological diseases. Nat. Med., 8, 455-457.
51. Yucesan, C. & Sriram, S. (2001) Chlamydia pneumoniae infection of the central nervous system. Curr. Opin. Neurol., 14, 355-359.