Helicobacter pylori: An intruder involved in conspiring glaucomatous neuropathy

British Journal of Ophthalmology

Volumn 93, Issue 11, 2009, Pages 1413-1415

  Kountouras, Jannis ^a  

^a NONE   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CORTICOTROPIN RELEASING FACTOR; CYTOKINE; HISTAMINE; IMMUNOGLOBULIN G ANTIBODY; INTERLEUKIN 6; INTERLEUKIN 8; TRYPTASE; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ALZHEIMER DISEASE; AUTOIMMUNITY; BLOOD BRAIN BARRIER; BORRELIA; CELL DEATH; CELLULAR IMMUNITY; CHLAMYDOPHILA PNEUMONIAE; DEGENERATIVE DISEASE; DISEASE ASSOCIATION; DISEASE COURSE; EDITORIAL; EXFOLIATIVE GLAUCOMA; GLAUCOMA; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HERPES SIMPLEX VIRUS 1; HISTOLOGY; HUMAN; OPEN ANGLE GLAUCOMA; OPTIC NERVE DISEASE; OXIDATIVE STRESS; PRIORITY JOURNAL; RETINA GANGLION CELL; RISK ASSESSMENT; SEROLOGY; UREA BREATH TEST;

BLOOD-BRAIN BARRIER; CELL DEATH; CYTOKINES; GLAUCOMA; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; OPTIC NERVE DISEASES; RETINAL GANGLION CELLS;

EID: 70350456131     PISSN: 00071161     EISSN: 14682079     Source Type: Journal    
DOI: 10.1136/bjo.2009.159046     Document Type: Editorial

References (42)

1. Johnson GJ, Foster PJ. Can we prevent angle-closure glaucoma? Eye 2005;19:1119-1124
2. McKinnon SJ. Glaucoma: ocular Alzheimer's disease? Front Biosci 2003;8:s1140-56.
3. Kountouras J, Gavalas E, Zavos C, et al. Alzheimer's disease and Helicobacter pylori infection: defective immune regulation and apoptosis as proposed common links. Med Hypotheses 2007;68:378-388 (Pubitemid 44879797)
4. Kountouras J, Zavos C, Chatzopoulos D. Induction of apoptosis as a proposed pathophysiological link between glaucoma and Helicobacter pylori infection. Med Hypotheses 2004;62:378-381 (Pubitemid 38388899)
5. Ritch R. Perspective on exfoliation syndrome. J Glaucoma 2001;10(1 Suppl):S33-5.
6. Ringvold A. Epidemiology of the pseudo-exfoliation syndrome. Acta Ophthalmol Scand 1999;77:371-375
7. Van Buskirk EM. Aphorisms of the hero. J Glaucoma 2003;12:189-192
8. Kountouras J, Mylopoulos N, Boura P, et al. Relationship between Helicobacter pylori infection and glaucoma. Ophthalmology 2001;108:599-604. (Pubitemid 32179904)
9. Kountouras J, Mylopoulos N, Chatzopoulos D, et al. Eradication of Helicobacter pylori may be beneficial in the management of chronic open-angle glaucoma. Arch Intern Med 2002;162:1237-1244 (Pubitemid 34595029)
10. Kountouras J, Mylopoulos N, Konstas AG, et al. Increased levels of Helicobacter pylori IgG antibodies in aqueous humor of patients with primary open-angle and exfoliation glaucoma. Graefes Arch Clin Exp Ophthalmol 2003;241:884-890 (Pubitemid 37527047)
11. Kountouras J, Tsolaki M, Gavalas E, et al. Relationship between Helicobacter pylori infection and Alzheimer disease. Neurology 2006;66:938-940 (Pubitemid 43739779)
12. Kountouras J, Tsolaki M, Boziki M, et al. Association between Helicobacter pylori infection and mild cognitive impairment. Eur J Neurol 2007;14:976-982 (Pubitemid 47300769)
13. Kountouras J, Boziki M, Gavalas E, et al. Eradication of Helicobacter pylori may be beneficial in the management of Alzheimer's disease. J Neurol 2009;256:758-767
14. Kountouras J, Boziki M, Gavalas E, et al. Increased cerebrospinal fluid Helicobacter pylori antibody in Alzheimer's disease. Int J Neurosci 2009;119:765-777
15. Izzotti A, Saccà SC, Bagnis A, et al. Glaucoma and Helicobacter pylori infection. Correlations and controversies. Br J Ophthalmol 2009;93:1420-1427
16. Kountouras J, Zavos C, Katsinelos P, et al. Helicobacter pylori infection and open-angle glaucoma association: comparison of Greek and Chinese data. Asian J Ophthalmol. In press.
17. Deshpande N, Lalitha P, Krishna das SR, et al. Helicobacter pylori IgG antibodies in aqueous humor and serum of subjects with primary open angle and pseudo-exfoliation glaucoma in a South Indian population. J Glaucoma 2008;17:605-610
18. Kountouras J, Zavos C, Chatzopoulos D. Helicobacter pylori and glaucoma. Ophthalmology 2003;110:2433-2434
19. Kountouras J, Zavos C, Katsinelos P, et al. Greek and Israeli patterns of Helicobacter pylori infection and their association with glaucoma: similarities or diversities? J Glaucoma 2008;17:503-504
20. Moshkowitz M, Konikoff FM, Arber N, et al. Seasonal variation in the frequency of Helicobacter pylori infection: a possible cause of the seasonal occurrence of peptic ulcer disease. Am J Gastroenterol 1994;89:731-733 (Pubitemid 24132056)
21. Kountouras J, Zavos C, Grigoriadis N, et al. Helicobacter pylori infection as a risk factor for primary open-angle glaucoma. Clin Exp Ophthalmol 2008;36:196.
22. Kountouras J, Zavos C, Grigoriadis N, et al. Helicobacter pylori infection as an enviromental familial clustering risk factor for primary open-angle glaucoma. Clin Experiment Ophthalmol 2008;36:296-297 (Pubitemid 351560285)
23. Kountouras J, Deretzi G, Zavos C, et al. Association between Helicobacter pylori infection and acute inflammatory demyelinating polyradiculoneuropathy. Eur J Neurol 2005;12:139-143 (Pubitemid 40260733)
24. Tamura H, Kawakami H, Kanamoto T, et al. High frequency of open-angle glaucoma in Japanese patients with Alzheimer's disease. J Neurol Sci 2006;246:79-83. (Pubitemid 43815345)
25. Kountouras J, Zavos C, Gavalas E, et al. Normal-tension glaucoma and Alzheimer's disease: Helicobacter pylori as a possible common underlying risk factor. Med Hypotheses 2007;68:228-229
26. Gavalas E, Kountouras J, Deretzi G, et al. Helicobacter pylori and multiple sclerosis. J Neuroimmunol 2007;188:187-189
27. Kountouras J, Gavalas E, Boziki M, et al. Helicobacter pylori may be involved in cognitive impairment and dementia development through induction of atrophic gastritis, vitamin B-12 - folate deficiency, and hyperhomocysteinemia sequence. Am J Clin Nutr 2007;86:805-806 (Pubitemid 47435851)
28. Kountouras J, Zavos C, Gavalas E, et al. Helicobacter pylori may hold a variable role in multiple sclerosis based on ethnicity. Med Hypotheses 2008;71:614-615
29. Kountouras J, Deretzi G, Grigoriadis N, et al. Guillain-Barré syndrome. Lancet Neurol 2008;7:1080-1081
30. Haorah J, Ramirez SH, Schall K, et al. Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood-brain barrier dysfunction. J Neurochem 2007;101:566-576 (Pubitemid 46525283)
31. Grieshaber MC, Flammer J. Does the blood-brain barrier play a role in glaucoma? Surv Ophthalmol 2007;52(2 Suppl):S115-21.
32. Kountouras J, Zavos C, Chatzopoulos D, et al. New aspects of Helicobacter pylori infection involvement in gastric oncogenesis. J Surg Res 2008;146:149-158
33. Keep RF, Xiang J, Ennis SR, et al. Blood-brain barrier function in intracerebral hemorrhage. Acta Neurochir Suppl 2008;105:73-77
34. Candelario-Jalil E, Taheri S, Yang Y, et al. Cyclooxygenase inhibition limits blood-brain barrier disruption following intracerebral injection of tumor necrosis factor-alpha in the rat. J Pharmacol Exp Ther 2007;323:488-498 (Pubitemid 350005134)
35. Mendall MA, Patel P, Asante M, et al. Relation of serum cytokine concentrations to cardiovascular risk factors and coronary heart disease. Heart 1997;78:273-277 (Pubitemid 27431736)
36. Guerreiro RJ, Santana I, Brás JM, et al. Peripheral inflammatory cytokines as biomarkers in Alzheimer's disease and mild cognitive impairment. Neurodegener Dis 2007;4:406-412 (Pubitemid 47557281)
37. Tan ZS, Beiser AS, Vasan RS, et al. Inflammatory markers and the risk of Alzheimer disease: the Framingham Study. Neurology 2007;68:1902-1908 (Pubitemid 46848622)
38. Supajatura V, Ushio H, Wada A, et al. Cutting edge: VacA, a vacuolating cytotoxin of Helicobacter pylori, directly activates mast cells for migration and production of proinflammatory cytokines. J Immunol 2002;168:2603-2607 (Pubitemid 34211634)
39. Kountouras J, Zavos C, Diamantidis MD, et al. A concept of Helicobacter pylori and stress-secreted mast cells' potential involvement in brain metastases. J Neuroimmunol 2009;209:121-122
40. Kountouras J, Zavos C, Chatzopoulos D. Primary open-angle glaucoma: pathophysiology and treatment. Lancet 2004;364:1311-1312 (Pubitemid 39335817)
41. Theoharides TC, Rozniecki JJ, Sahagian G, et al. Impact of stress and mast cells on brain metastases. J Neuroimmunol 2008;205:1-7.
42. Itzhaki RF, Wozniak MA, Appelt DM, et al. Infiltration of the brain by pathogens causes Alzheimer's disease. Neurobiol Aging 2004;25:619-627 (Pubitemid 38686484)