Oxidative stress and DNA damage after cerebral ischemia: Potential therapeutic targets to repair the genome and improve stroke recovery

Neuropharmacology

Volumn 134, Issue , 2018, Pages 208-217

  Li, Peiying ^a,b   Stetler, R Anne ^a   Leak, Rehana K ^c   Shi, Yejie ^a   Li, Yan ^b   Yu, Weifeng ^b   Bennett, Michael V L ^d   Chen, Jun ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c DUQUESNE UNIVERSITY   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Axonal regeneration; Cerebral ischemia; DNA damage; DNA repair; Neurogenesis; Neurovascular remodeling; Oxidative stress; Stroke recovery; White matter repair

Indexed keywords

APE1 PROTEIN; DNA; DNA DIRECTED DNA POLYMERASE BETA; DNA REPAIR PROTEIN XRCC1; GADD45B PROTEIN; NEIL3 PROTEIN; OGG1 PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

BRAIN ISCHEMIA; CELL DEATH; CEREBROVASCULAR ACCIDENT; CLINICAL OUTCOME; CONVALESCENCE; CORRELATION ANALYSIS; DNA DAMAGE; DNA REPAIR; DRUG TARGETING; EXCISION REPAIR; GENOME; GLIA CELL; HUMAN; NERVE CELL; NERVE FIBER REGENERATION; NERVE REGENERATION; NERVOUS SYSTEM DEVELOPMENT; NON-HOMOGENOUS ENDPOINT JOINTING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW; TISSUE REPAIR; UPREGULATION; WHITE MATTER; ANIMAL; COMPLICATION; GENETICS; PHYSIOLOGY;

ANIMALS; BRAIN ISCHEMIA; DNA DAMAGE; GENOME; HUMANS; OXIDATIVE STRESS; RECOVERY OF FUNCTION; STROKE;

EID: 85033802078     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2017.11.011     Document Type: Review

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