Interleukin-4 Is Essential for Microglia/Macrophage M2 Polarization and Long-Term Recovery after Cerebral Ischemia

Stroke

Volumn 47, Issue 2, 2016, Pages 498-504

  Liu, Xiangrong ^a,b   Liu, Jia ^b,c   Zhao, Shangfeng ^a   Zhang, Haiyue ^a   Cai, Wei ^a   Cai, Mengfei ^e   Ji, Xunming ^d   Leak, Rehana K ^d   Gao, Yanqin ^a   Chen, Jun ^a,c   Hu, Xiaoming ^a,c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c FUDAN UNIVERSITY   (China)

^d DUQUESNE UNIVERSITY   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Flow cytometry; Interleukin 4Mmacrophages; Neurological function; Stroke

Indexed keywords

CD16 ANTIGEN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 4; TUMOR NECROSIS FACTOR ALPHA; CELL SURFACE RECEPTOR; IL4RA PROTEIN, MOUSE; IMMUNOLOGICAL ADJUVANT; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN ISCHEMIA; COGNITION; CONTROLLED STUDY; IMMUNOMODULATION; MACROPHAGE; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; MORRIS WATER MAZE TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REPERFUSION INJURY; ANIMAL; ANIMAL BEHAVIOR; C57BL MOUSE; DRUG EFFECTS; GENETICS; IMMUNOLOGY; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; KNOCKOUT MOUSE; METABOLISM; NEUROPSYCHOLOGICAL TEST;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; BEHAVIOR, ANIMAL; BRAIN ISCHEMIA; INFUSIONS, INTRAVENTRICULAR; INTERLEUKIN-4; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; NEUROPSYCHOLOGICAL TESTS; RECEPTORS, CELL SURFACE; REPERFUSION INJURY; RNA, MESSENGER;

EID: 84953275134     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.115.012079     Document Type: Article

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