Intranuclear matrix metalloproteinases promote DNA damage and apoptosis induced by oxygen-glucose deprivation in neurons

Neuroscience

Volumn 220, Issue , 2012, Pages 277-290

  Hill, J W ^a   Poddar, R ^a   Thompson, J F ^a   Rosenberg, G A ^a   Yang, Y ^a  

^a UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

Author keywords

DNA repair; Matrix metalloproteinase; Neuronal apoptosis; Oxidative DNA damage; Stroke

Indexed keywords

GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE INHIBITOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; XRCC1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CELL; BRAIN ISCHEMIA; CELL SURVIVAL; CONTROLLED STUDY; DISEASE MODEL; DNA DAMAGE; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME SUBSTRATE; IN VITRO STUDY; IN VIVO STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL NECROSIS; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; OXYGEN GLUCOSE DEPRIVATION; PRIORITY JOURNAL; RAT; REOXYGENATION; REPERFUSION;

ANIMALS; ANOXIA; APOPTOSIS; BRAIN ISCHEMIA; CELL NUCLEUS; CELLS, CULTURED; DNA DAMAGE; ENZYME ACTIVATION; GLUCOSE; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NEURONS; RATS; RATS, INBRED SHR; STROKE;

EID: 84864770380     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.06.019     Document Type: Article

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