Early inhibition of MMP activity in ischemic rat brain promotes expression of tight junction proteins and angiogenesis during recovery

Journal of Cerebral Blood Flow and Metabolism

Volumn 33, Issue 7, 2013, Pages 1104-1114

  Yang, Yi ^a   Thompson, Jeffrey F ^a   Taheri, Saeid ^b   Salayandia, Victor M ^a   Mcavoy, Thera A ^a   Hill, Jeff W ^a   Yang, Yirong ^c   Estrada, Eduardo Y ^a   Rosenberg, Gary A ^a  

^a UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c UNIVERSITY OF NEW MEXICO   (United States)

Author keywords

astrocytes; blood brain barrier; brain recovery; focal ischemia; matrix proteinases; pericytes angiogenesis

Indexed keywords

CLAUDIN 5; GELATINASE A; ILOMASTAT; OCCLUDIN; PROTEIN ZO1; STROMELYSIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BIOCHEMISTRY; BLOOD BRAIN BARRIER; BRAIN BLOOD FLOW; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONFOCAL MICROSCOPY; CONTRAST ENHANCEMENT; CONTROLLED STUDY; CONVALESCENCE; ENDOTHELIUM CELL; ENZYME INHIBITION; HYPERTENSION; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOLECULAR MECHANICS; NEUROPROTECTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PERICYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; WESTERN BLOTTING;

ANIMALS; BLOOD-BRAIN BARRIER; BLOTTING, WESTERN; BRAIN ISCHEMIA; CELL DEATH; DIPEPTIDES; DNA FRAGMENTATION; IN SITU NICK-END LABELING; MAGNETIC RESONANCE IMAGING; MALE; MATRIX METALLOPROTEINASE INHIBITORS; MATRIX METALLOPROTEINASES; NEOVASCULARIZATION, PHYSIOLOGIC; RATS; RATS, INBRED SHR; TIGHT JUNCTION PROTEINS;

EID: 84880331059     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2013.56     Document Type: Article

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