Granulocyte colony-stimulating factor attenuates delayed tPA-induced hemorrhagic transformation in ischemic stroke rats by enhancing angiogenesis and vasculogenesis

Journal of Cerebral Blood Flow and Metabolism

Volumn 35, Issue 2, 2015, Pages 338-346

  Dela Peña, Ike C ^a   Yoo, Arum ^a   Tajiri, Naoki ^a   Acosta, Sandra A ^a   Ji, Xunming ^b   Kaneko, Yuji ^a   Borlongan, Cesar V ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

angiogenesis; EPCs; G CSF; hemorrhagic transformation; tPA; vasculogenesis

Indexed keywords

ANGIOPOIETIN 1; ANGIOTENSIN II; BETA ACTIN; CD34 ANTIGEN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GRANULOCYTE COLONY STIMULATING FACTOR; HEMOGLOBIN; NITRIC OXIDE SYNTHASE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; SUNITINIB; TISSUE PLASMINOGEN ACTIVATOR; VASCULAR ENDOTHELIAL CADHERIN; VASCULOTROPIN RECEPTOR 2; VON WILLEBRAND FACTOR;

ADULT; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEEDING DISORDER; BRAIN CORTEX; BRAIN FUNCTION; BRAIN HEMORRHAGE; BRAIN HISTOLOGY; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN PROTECTION; CONTROLLED STUDY; CORPUS STRIATUM; DISEASE SEVERITY; DRUG EFFICACY; ENDOTHELIUM CELL; HEMORRHAGIC TRANSFORMATION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THERAPY DELAY; UPREGULATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CHEMICALLY INDUCED; DRUG EFFECTS; GENE EXPRESSION REGULATION; INTRACRANIAL HEMORRHAGES; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT; STROKE;

ANIMALS; ANTIGENS, CD34; BRAIN ISCHEMIA; CEREBRAL CORTEX; CORPUS STRIATUM; GENE EXPRESSION REGULATION; INTRACRANIAL HEMORRHAGES; MALE; NEOVASCULARIZATION, PHYSIOLOGIC; RATS; RATS, SPRAGUE-DAWLEY; STROKE; TISSUE PLASMINOGEN ACTIVATOR; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; VON WILLEBRAND FACTOR;

EID: 84922337342     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2014.208     Document Type: Article

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