Macrophage-derived osteopontin induces reactive astrocyte polarization and promotes re-establishment of the blood brain barrier after ischemic stroke

GLIA

Volumn 63, Issue 12, 2015, Pages 2198-2207

  Gliem, Michael ^a   Krammes, Kristina ^a   Liaw, Lucy ^b   van Rooijen, Nico ^c   Hartung, Hans Peter ^a   Jander, Sebastian ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b Maine Medical Center Research Institute   (United States)

^c VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Macrophages; Osteopontin; Reactive astrocytes; Scarring; Stroke

Indexed keywords

CLODRONIC ACID; LIPOSOME; OSTEOPONTIN; AQP4 PROTEIN, MOUSE; AQUAPORIN 4; CCR2 PROTEIN, MOUSE; CHEMOKINE RECEPTOR CCR2; SPP1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; BONE MARROW; BRAIN ISCHEMIA; CELL POLARITY; ENDOTHELIUM CELL; MACROPHAGE; MALE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BRAIN; C57BL MOUSE; CEREBROVASCULAR ACCIDENT; DISEASE MODEL; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; AQUAPORIN 4; ASTROCYTES; BLOOD-BRAIN BARRIER; BRAIN; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; MACROPHAGES; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; OSTEOPONTIN; RECEPTORS, CCR2; STROKE;

EID: 84943579915     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22885     Document Type: Article

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