Dysregulation of neurotrophin signaling in the pathogenesis of Alzheimer disease and of Alzheimer disease in Down syndrome

Free Radical Biology and Medicine

Volumn 114, Issue , 2018, Pages 52-61

  Chen, Xu Qiao ^a   Sawa, Mariko ^a   Mobley, William C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alzheimer's disease; Axonal transport deficit; Degeneration; Down syndrome; Endosome enlargement; Neurotrophin; Signaling endosome

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; NERVE GROWTH FACTOR; NEUROTROPHIN; RAB PROTEIN;

ALZHEIMER DISEASE; APP GENE; BIODIVERSITY; CELL FUNCTION; CELL STRUCTURE; CHROMOSOME 21; CYTOLOGY; DOWN SYNDROME; ENDOSOME; ENZYME ACTIVATION; GENE; GENE EXPRESSION; HUMAN; NERVE CELL; NERVE DEGENERATION; NERVE FIBER TRANSPORT; NERVOUS SYSTEM; NEURO-2A CELL LINE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFECT; REVIEW; SIGNAL TRANSDUCTION; ANIMAL; COMPLICATION; METABOLISM; PATHOLOGY;

ALZHEIMER DISEASE; ANIMALS; DOWN SYNDROME; ENDOSOMES; HUMANS; NERVE GROWTH FACTORS;

EID: 85031506618     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2017.10.341     Document Type: Review

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