Significant effect of APOE epsilon 4 genotype on the risk of dementia in Alzheimer's disease and mortality in persons with Down syndrome

International Journal of Geriatric Psychiatry

Volumn 23, Issue 11, 2008, Pages 1134-1140

  Prasher, V P ^a,b   Sajith, S G ^a   Rees, S D ^c   Patel, A ^d   Tewari, S ^e   Schupf, N ^f   Zigman, W B ^g  

^a Monyhull Hospital   (United Kingdom)

^b LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^d Institute for Clean Growth and Future Mobility   (United Kingdom)

^e Lea Castle Centre   (United Kingdom)

^f NewYork Presbyterian Hospital   (United States)

^g NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

Author keywords

Alzheimer's disease; Apolipoprotein E; Dementia; Down syndrome; Mortality

Indexed keywords

APOLIPOPROTEIN E; APOLIPOPROTEIN E EPSILON 4; UNCLASSIFIED DRUG;

ADULT; AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; CLINICAL TRIAL; DEMENTIA; DOWN SYNDROME; FEMALE; GENE FREQUENCY; GENETIC RISK; GENETIC SCREENING; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MORTALITY; RISK ASSESSMENT;

ALLELES; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; DISEASE PROGRESSION; DOWN SYNDROME; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; GENOTYPE; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RISK ASSESSMENT; SURVIVAL ANALYSIS;

EID: 58649119608     PISSN: 08856230     EISSN: 10991166     Source Type: Journal    
DOI: 10.1002/gps.2039     Document Type: Article

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