The small GTPase Rab7 controls the endosomal trafficking and neuritogenic signaling of the nerve growth factor receptor TrkA

Journal of Neuroscience

Volumn 25, Issue 47, 2005, Pages 10930-10940

  Saxena, Smita ^a,d   Bucci, Cecilia ^b   Weis, Joachim ^a,c   Kruttgen, Alex ^a,c  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF SALENTO   (Italy)

^c UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^d FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

Author keywords

Charcot Marie Tooth; Neurite outgrowth; Neurodegeneration; Neurotrophin; Polyneuropathy; Retrograde transport

Indexed keywords

GREEN FLUORESCENT PROTEIN; GUANOSINE TRIPHOSPHATASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE A; RAB7 PROTEIN;

ANIMAL CELL; ARTICLE; CELL SURFACE; CELL SURVIVAL; CONTROLLED STUDY; DEGENERATIVE DISEASE; ENDOSOME; ENZYME ACTIVATION; HEREDITARY MOTOR SENSORY NEUROPATHY; IMMUNOPRECIPITATION; INTERNALIZATION; NERVE FIBER GROWTH; NONHUMAN; POLYNEUROPATHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CELLS, CULTURED; ENDOSOMES; GANGLIA, SPINAL; NERVE GROWTH FACTOR; NEURITES; NEURONS; PC12 CELLS; PROTEIN TRANSPORT; RAB GTP-BINDING PROTEINS; RATS; RECEPTOR, TRKA; SIGNAL TRANSDUCTION;

EID: 28044444522     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2029-05.2005     Document Type: Article

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