Enhancing Protein Production Yield from Chinese Hamster Ovary Cells by CRISPR Interference

ACS Synthetic Biology

Volumn 6, Issue 8, 2017, Pages 1509-1519

  Shen, Chih Che ^a   Sung, Li Yu ^a   Lin, Shih Yeh ^a   Lin, Mei Wei ^a   Hu, Yu Chen ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

cell engineering; CHO cell; CRISPRi; DHFR; MTX selection; protein production

Indexed keywords

RECOMBINANT PROTEIN;

ANIMAL; BIOSYNTHESIS; CHO CELL LINE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CRICETULUS; GENE VECTOR; GENETIC ENHANCEMENT; GENETIC TRANSFECTION; GENETICS; HAMSTER; PHYSIOLOGY; PROCEDURES; PROTEIN ENGINEERING;

ANIMALS; CHO CELLS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRICETINAE; CRICETULUS; GENETIC ENHANCEMENT; GENETIC VECTORS; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 85027557002     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/acssynbio.7b00020     Document Type: Article

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