Functional evolution of influenza virus NS1 protein in currently circulating human 2009 pandemic H1N1 viruses

Journal of Virology

Volumn 91, Issue 17, 2017, Pages

  Clark, Amelia M ^a   Nogales, Aitor ^a   Martinez Sobrido, Luis ^a   Topham, David J ^a   DeDiego, Marta L ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

CPSF30; Influenza virus; Innate immune response; NS1 protein; Pathogenesis; Virus host interaction

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 30; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IFIT2 PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; NONSTRUCTURAL PROTEIN 1; PEPTIDES AND PROTEINS; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CPSF30 PROTEIN, HUMAN; INS1 PROTEIN, INFLUENZA VIRUS; VIRAL PROTEIN;

2009 H1N1 INFLUENZA; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; IN VITRO STUDY; INFLUENZA A (H1N1); INNATE IMMUNITY; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; TETRATRICOPEPTIDE REPEAT; VIROGENESIS; VIRUS CELL INTERACTION; VIRUS TITRATION; VIRUS VIRULENCE; ANIMAL; BINDING SITE; C57BL MOUSE; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; HOST PATHOGEN INTERACTION; INFLUENZA A VIRUS (H1N1); METABOLISM; MOLECULAR EVOLUTION; MOUSE; MUTATION; ORTHOMYXOVIRUS INFECTION; PATHOGENICITY; VIROLOGY; VIRULENCE; VIRUS REPLICATION;

ANIMALS; BINDING SITES; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; EVOLUTION, MOLECULAR; FEMALE; GENE EXPRESSION REGULATION, VIRAL; HEK293 CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, INNATE; INFLUENZA A VIRUS, H1N1 SUBTYPE; MICE; MICE, INBRED C57BL; MUTATION; ORTHOMYXOVIRIDAE INFECTIONS; VIRAL NONSTRUCTURAL PROTEINS; VIRULENCE; VIRUS REPLICATION;

EID: 85027300372     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00721-17     Document Type: Article

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