A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis

Virology

Volumn 363, Issue 1, 2007, Pages 236-243

  Min, Ji Young ^a   Li, Shoudong ^b   Sen, Ganes C ^b   Krug, Robert M ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Influenza A virus; NS1 protein; PKR activation; Viral RNA synthesis

Indexed keywords

ALANINE DERIVATIVE; AMINO ACID; INITIATION FACTOR 2ALPHA; NS1 PROTEIN; PROTEIN KINASE; UNCLASSIFIED DRUG; VIRUS ENZYME; VIRUS PROTEIN; VIRUS RNA;

AMINO ACID SEQUENCE; ARTICLE; CELL NUCLEUS; CYTOPLASM; ENZYME ACTIVATION; ENZYME BINDING; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLUENZA VIRUS A; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; RNA SYNTHESIS; VIRUS INFECTION; WILD TYPE;

ANIMALS; BINDING SITES; CELL LINE; DOGS; EIF-2 KINASE; ENZYME ACTIVATION; GENE DELETION; INFLUENZA A VIRUS; MICE; MUTATION; PHENOTYPE; RNA, VIRAL; TIME FACTORS; VIRAL NONSTRUCTURAL PROTEINS;

INFLUENZA A VIRUS;

EID: 34247566514     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2007.01.038     Document Type: Article

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