Contribution of double-stranded RNA and CPSF30 binding domains of influenza virus NS1 to the inhibition of type I interferon production and activation of human dendritic cells

Journal of Virology

Volumn 87, Issue 5, 2013, Pages 2430-2440

  Ramos, Irene ^a   Carnero, Elena ^a,b   Bernal Rubio, Dabeiba ^a   Seibert, Christopher W ^a   Westera, Liset ^a,c   García Sastre, Adolfo ^a   Fernandez Sesma, Ana ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NAVARRA   (Spain)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 30; DOUBLE STRANDED RNA; MESSENGER RNA; NONSTRUCTURAL PROTEIN 1; UNCLASSIFIED DRUG;

ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; HUMAN; HUMAN CELL; INFLAMMATION; INFLUENZA A; INFLUENZA VIRUS; INHIBITION KINETICS; INNATE IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; PROTEIN TARGETING; RNA ANALYSIS; VIRUS CELL INTERACTION; VIRUS RECOMBINANT; VIRUS REPLICATION; VIRUS STRAIN;

ANIMALS; CELLS, CULTURED; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; DENDRITIC CELLS; DOGS; HUMANS; IMMUNITY, INNATE; INFLUENZA A VIRUS; INTERFERON TYPE I; INTERLEUKIN-6; MADIN DARBY CANINE KIDNEY CELLS; NF-KAPPA B; PROTEIN STRUCTURE, TERTIARY; RNA, DOUBLE-STRANDED; RNA, VIRAL; TUMOR NECROSIS FACTOR-ALPHA; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 84874690730     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02247-12     Document Type: Article

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