A cell-based luciferase assay amenable to high-throughput screening of inhibitors of arenavirus budding

Virology

Volumn 382, Issue 1, 2008, Pages 107-114

  Capul, Althea A ^a   de la Torre, Juan Carlos ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Arenavirus; Gaussia luciferase; High throughput screen; Lassa fever virus; Virus budding; Z protein

Indexed keywords

2 HYDOXYMYRISTIC ACID; ANTIVIRUS AGENT; LUCIFERASE; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS PROTEIN Z;

ANTIVIRAL ACTIVITY; ARENAVIRUS; ARTICLE; CELL ASSAY; CONTROLLED STUDY; DRUG IDENTIFICATION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; VIRUS CELL INTERACTION;

ANTIVIRAL AGENTS; ARENAVIRUS; DRUG EVALUATION, PRECLINICAL; GENES, REPORTER; HUMANS; LUCIFERASES; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; STAINING AND LABELING;

ARENAVIRUS; LASSA VIRUS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS;

EID: 55249103820     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2008.09.008     Document Type: Article

References (53)

1. Barton L.L. LCMV transmission by organ transplantation. N. Engl. J. Med. 355 16 (2006) 1737 author reply 1737-8
2. Barton L.L., Mets M.B., and Beauchamp C.L. Lymphocytic choriomeningitis virus: emerging fetal teratogen. Am. J. Obstet. Gynecol. 187 6 (2002) 1715-1716
3. Borden K.L., Campbell Dwyer E.J., and Salvato M.S. An arenavirus RING (zinc-binding) protein binds the oncoprotein promyelocyte leukemia protein (PML) and relocates PML nuclear bodies to the cytoplasm. J. Virol. 72 1 (1998) 758-766
4. Borio L., Inglesby T., Peters C.J., Schmaljohn A.L., Hughes J.M., Jahrling P.B., Ksiazek T., Johnson K.M., Meyerhoff A., O'Toole T., Ascher M.S., Bartlett J., Breman J.G., Eitzen Jr. E.M., Hamburg M., Hauer J., Henderson D.A., Johnson R.T., Kwik G., Layton M., Lillibridge S., Nabel G.J., Osterholm M.T., Perl T.M., Russell P., and Tonat K. Hemorrhagic fever viruses as biological weapons: medical and public health management. JAMA 287 18 (2002) 2391-2405
5. Buchmeier M.J., and Oldstone M.B. Protein structure of lymphocytic choriomeningitis virus: evidence for a cell-associated precursor of the virion glycopeptides. Virology 99 1 (1979) 111-120
6. Buchmeier M.J., de la Torre J.-C., and Peters C. Arenaviridae: the viruses and their replication. In: Knipe D.M., and Howley P.M. (Eds). Fields Virology. Fifth ed. Vol. 2 (2007), Wolters Kluwer Health/Lippincott Williams and Wilkins, Philadelphia 1792-1827 2 vols
7. Campbell Dwyer E.J., Lai H., MacDonald R.C., Salvato M.S., and Borden K.L. The lymphocytic choriomeningitis virus RING protein Z associates with eukaryotic initiation factor 4E and selectively represses translation in a RING-dependent manner. J. Virol. 74 7 (2000) 3293-3300
8. Capul A.A., Perez M., Burke E., Kunz S., Buchmeier M.J., and de la Torre J.C. Arenavirus Z-glycoprotein association requires Z myristoylation but not functional RING or late domains. J. Virol. 81 17 (2007) 9451-9460
9. Craven R.C., Harty R.N., Paragas J., Palese P., and Wills J.W. Late domain function identified in the vesicular stomatitis virus M protein by use of rhabdovirus-retrovirus chimeras. J. Virol. 73 4 (1999) 3359-3365
10. Dalton A.J., Rowe W.P., Smith G.H., Wilsnack R.E., and Pugh W.E. Morphological and cytochemical studies on lymphocytic choriomeningitis virus. J. Virol. 2 12 (1968) 1465-1478
11. Eichler R., Strecker T., Kolesnikova L., ter Meulen J., Weissenhorn W., Becker S., Klenk H.D., Garten W., and Lenz O. Characterization of the Lassa virus matrix protein Z: electron microscopic study of virus-like particles and interaction with the nucleoprotein (NP). Virus. Res. 100 2 (2004) 249-255
12. Eschli B., Quirin K., Wepf A., Weber J., Zinkernagel R., and Hengartner H. Identification of an N-terminal trimeric coiled-coil core within arenavirus glycoprotein 2 permits assignment to class I viral fusion proteins. J. Virol. 80 12 (2006) 5897-5907
13. Flatz L., Bergthaler A., de la Torre J.C., and Pinschewer D.D. Recovery of an arenavirus entirely from RNA polymerase I/II-driven cDNA. Proc. Natl. Acad. Sci. U. S. A. 103 12 (2006) 4663-4668
14. Garrus J.E., von Schwedler U.K., Pornillos O.W., Morham S.G., Zavitz K.H., Wang H.E., Wettstein D.A., Stray K.M., Cote M., Rich R.L., Myszka D.G., and Sundquist W.I. Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding. Cell 107 1 (2001) 55-65
15. Geisbert T.W., and Jahrling P.B. Exotic emerging viral diseases: progress and challenges. Nat. Med. 10 12 Suppl (2004) S110-121
16. Gross S., and Piwnica-Worms D. Spying on cancer: molecular imaging in vivo with genetically encoded reporters. Cancer Cell 7 1 (2005) 5-15
17. Harty R.N., Brown M.E., Wang G., Huibregtse J., and Hayes F.P. A PPxY motif within the VP40 protein of Ebola virus interacts physically and functionally with a ubiquitin ligase: implications for filovirus budding. Proc. Natl. Acad. Sci. U. S. A. 97 25 (2000) 13871-13876
18. Hass M., Golnitz U., Muller S., Becker-Ziaja B., and Gunther S. Replicon system for Lassa virus. J. Virol. 78 24 (2004) 13793-13803
19. Jahrling P.B., and Peters C.J. Lymphocytic choriomeningitis virus. A neglected pathogen of man. Arch. Pathol. Lab. Med. 116 5 (1992) 486-488
20. Knappskog S., Ravneberg H., Gjerdrum C., Trosse C., Stern B., and Pryme I.F. The level of synthesis and secretion of Gaussia princeps luciferase in transfected CHO cells is heavily dependent on the choice of signal peptide. J. Biotechnol. 128 4 (2007) 705-715
21. Kunz S., Edelmann K.H., de la Torre J.C., Gorney R., and Oldstone MB. Mechanisms for lymphocytic choriomeningitis virus glycoprotein cleavage, transport, and incorporation into virions. Virology 314 (2003) 168-178
22. Lee K.J., Novella I.S., Teng M.N., Oldstone M.B., and de La Torre J.C. NP and L proteins of lymphocytic choriomeningitis virus (LCMV) are sufficient for efficient transcription and replication of LCMV genomic RNA analogs. J. Virol. 74 8 (2000) 3470-3477
23. Lee K.J., Perez M., Pinschewer D.D., and de la Torre J.C. Identification of the lymphocytic choriomeningitis virus (LCMV) proteins required to rescue LCMV RNA analogs into LCMV-like particles. J. Virol. 76 12 (2002) 6393-6397
24. Lenard J. Negative-strand virus M and retrovirus MA proteins: all in a family?. Virology 216 2 (1996) 289-298
25. Lopez N., Jacamo R., and Franze-Fernandez M.T. Transcription and RNA replication of Tacaribe virus genome and antigenome analogs require N and L proteins: Z protein is an inhibitor of these processes. J. Virol. 75 24 (2001) 12241-12251
26. Martin-Serrano J., Zang T., and Bieniasz P.D. HIV-1 and Ebola virus encode small peptide motifs that recruit Tsg101 to sites of particle assembly to facilitate egress. Nat. Med. 7 12 (2001) 1313-1319
27. McCarthy S.E., Licata J.M., and Harty R.N. A luciferase-based budding assay for Ebola virus. J. Virol. Methods 137 1 (2006) 115-119
28. McCormick J.B., and Fisher-Hoch S.P. Lassa fever. In: Oldstone M.B. (Ed). Arenaviruses I Vol. 262 (2002), Springer-Verlag, Berlin, Heidelberg 75-110
29. McKee Jr. K.T., Huggins J.W., Trahan C.J., and Mahlandt B.G. Ribavirin prophylaxis and therapy for experimental argentine hemorrhagic fever. Antimicrob. Agents Chemother. 32 9 (1988) 1304-1309
30. Mets M.B., Barton L.L., Khan A.S., and Ksiazek T.G. Lymphocytic choriomeningitis virus: an underdiagnosed cause of congenital chorioretinitis. Am. J. Ophthalmol. 130 2 (2000) 209-215
31. Murphy F.A., Webb P.A., Johnson K.M., Whitfield S.G., and Chappell W.A. Arenoviruses in Vero cells: ultrastructural studies. J. Virol. 6 4 (1970) 507-518
32. Nielsen H., Brunak S., and von Heijne G. Machine learning approaches for the prediction of signal peptides and other protein sorting signals. Protein Eng. 12 1 (1999) 3-9
33. Niwa H., Yamamura K., and Miyazaki J. Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 108 2 (1991) 193-199
34. Opaluch A.M., Aza-Blanc P., Vang T., Williams S., Tautz L., Milan L., and Mustelin T. PTPome-wide functional RNA interference screening methods. Methods 42 3 (2007) 306-312
35. Palacios G., Druce J., Du L., Tran T., Birch C., Briese T., Conlan S., Quan P.L., Hui J., Marshall J., Simons J.F., Egholm M., Paddock C.D., Shieh W.J., Goldsmith C.S., Zaki S.R., Catton M., and Lipkin W.I. A new arenavirus in a cluster of fatal transplant-associated diseases. N. Engl. J. Med. 358 10 (2008) 991-998
36. Patch J.R., Crameri G., Wang L.F., Eaton B.T., and Broder C.C. Quantitative analysis of Nipah virus proteins released as virus-like particles reveals central role for the matrix protein. Virol. J. 4 (2007) 1
37. Perez M., Craven R.C., and de la Torre J.C. The small RING finger protein Z drives arenavirus budding: implications for antiviral strategies. Proc. Natl. Acad. Sci. U. S. A. 100 22 (2003) 12978-12983
38. Perez M., Greenwald D.L., and de la Torre J.C. Myristoylation of the RING finger Z protein is essential for arenavirus budding. J. Virol. 78 20 (2004) 11443-11448
39. Peters C.J. Human infection with arenaviruses in the Americas. In: Oldstone M.B. (Ed). Arenaviruses I Vol. 262 (2002), Springer-Verlag, Berlin Heidelberg 65-74
40. Pinschewer D.D., Perez M., Sanchez A.B., and de la Torre J.C. Recombinant lymphocytic choriomeningitis virus expressing vesicular stomatitis virus glycoprotein. Proc. Natl. Acad. Sci. U. S. A. 100 13 (2003) 7895-7900
41. Remy I., and Michnick S.W. A highly sensitive protein-protein interaction assay based on Gaussia luciferase. Nat. Methods 3 12 (2006) 977-979
42. Sambrook J., Fritsch E.F., and Maniatis T. Molecular Cloning: A Laboratory Manual. 2 ed. (1989), Cold Spring Harbor Laboratory Press
43. Sanchez A.B., and de la Torre J.C. Rescue of the prototypic Arenavirus LCMV entirely from plasmid. Virology 350 2 (2006) 370-380
44. Singh P., Harden B.J., Lillywhite B.J., and Broad P.M. Identification of kinase inhibitors by an ATP depletion method. Assay. Drug. Dev. Technol. 2 2 (2004) 161-169
45. Stankunas K., Bayle J.H., Havranek J.J., Wandless T.J., Baker D., Crabtree G.R., and Gestwicki J.E. Rescue of degradation-prone mutants of the FK506-rapamycin binding (FRB) protein with chemical ligands. Chembiochem 8 10 (2007) 1162-1169
46. Strecker T., Eichler R., Meulen J., Weissenhorn W., Dieter Klenk H., Garten W., and Lenz O. Lassa virus Z protein is a matrix protein and sufficient for the release of virus-like particles [corrected]. J. Virol. 77 19 (2003) 10700-10705
47. Strecker T., Maisa A., Daffis S., Eichler R., Lenz O., and Garten W. The role of myristoylation in the membrane association of the Lassa virus matrix protein Z. Virol. J. 3 (2006) 93
48. Tannous B.A., Kim D.E., Fernandez J.L., Weissleder R., and Breakefield X.O. Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo. Mol. Ther. 11 3 (2005) 435-443
49. Topcu Z., Mack D.L., Hromas R.A., and Borden K.L. The promyelocytic leukemia protein PML interacts with the proline-rich homeodomain protein PRH: a RING may link hematopoiesis and growth control. Oncogene 18 50 (1999) 7091-7100
50. Urata S., Noda T., Kawaoka Y., Yokosawa H., and Yasuda J. Cellular factors required for Lassa virus budding. J. Virol. 80 8 (2006) 4191-4195
51. VerPlank L., Bouamr F., LaGrassa T.J., Agresta B., Kikonyogo A., Leis J., and Carter C.A. Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55(Gag). Proc. Natl. Acad. Sci. U. S. A. 98 14 (2001) 7724-7729
52. York J., Romanowski V., Lu M., and Nunberg J.H. The signal peptide of the Junin arenavirus envelope glycoprotein is myristoylated and forms an essential subunit of the mature G1-G2 complex. J. Virol. 78 19 (2004) 10783-10792
53. Zhang J.H., Chung T.D., and Oldenburg K.R. A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J. Biomol. Screen. 4 2 (1999) 67-73