O-GlcNAc regulation of autophagy and α-synuclein homeostasis; Implications for Parkinson's disease

Molecular Brain

Volumn 10, Issue 1, 2017, Pages

  Wani, Willayat Y ^a   Ouyang, Xiaosen ^a   Benavides, Gloria A ^a   Redmann, Matthew ^a   Cofield, Stacey S ^b   Shacka, John J ^b,c   Chatham, John C ^a   Darley Usmar, Victor ^a   Zhang, Jianhua ^a,b  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c University of Alabama at Birmingham   (United States)

Author keywords

Akt; Autophagy; Mitochondria; mTOR; O GlcNAcylation; Parkinson's disease; Proteasome; Rapamycin; Thiamet G; synuclein

Indexed keywords

ALPHA SYNUCLEIN; MAMMALIAN TARGET OF RAPAMYCIN; N ACETYLGLUCOSAMINE; PROTEASOME; PROTEIN KINASE B; RAPAMYCIN; SERINE; THREONINE; TRANSFERASE INHIBITOR; GLUCOSAMINE; PYRAN DERIVATIVE; TARGET OF RAPAMYCIN KINASE; THIAMET G; THIAZOLE DERIVATIVE;

ANIMAL CELL; ARTICLE; AUTOPHAGY; AUTOPSY; BRAIN CELL; CELL FUNCTION; CELL LYSATE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; INHIBITION KINETICS; NERVE CELL; NONHUMAN; OXIDATION REDUCTION STATE; PARKINSON DISEASE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN PROCESSING; RAT; TEMPORAL CORTEX; ANIMAL; BIOLOGICAL MODEL; CELL CULTURE; DRUG EFFECTS; GLYCOSYLATION; HOMEOSTASIS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; POSTMORTEM CHANGE; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ALPHA-SYNUCLEIN; ANIMALS; AUTOPHAGY; CELLS, CULTURED; GLUCOSAMINE; GLYCOSYLATION; HOMEOSTASIS; HUMANS; MODELS, BIOLOGICAL; NEURONS; PARKINSON DISEASE; PHOSPHORYLATION; POSTMORTEM CHANGES; PROTO-ONCOGENE PROTEINS C-AKT; PYRANS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SIROLIMUS; THIAZOLES; TOR SERINE-THREONINE KINASES;

EID: 85024847491     PISSN: None     EISSN: 17566606     Source Type: Journal    
DOI: 10.1186/s13041-017-0311-1     Document Type: Article

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