Decreased O-linked GlcNAcylation protects from cytotoxicity mediated by huntingtin exon1 protein fragment

Journal of Biological Chemistry

Volumn 289, Issue 19, 2014, Pages 13543-13553

  Kumar, Amit ^a,c   Singh, Pankaj Kumar ^a,d   Parihar, Rashmi ^a   Dwivedi, Vibha ^b   Lakhotia, Subhash C ^b   Ganesh, Subramaniam ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY KANPUR   (India)

^b BANARAS HINDU UNIVERSITY   (India)

^c BURKE MEDICAL RESEARCH INSTITUTE   (United States)

^d INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS;

AUTOPHAGOSOME; CELLULAR HOMEOSTASIS; CELLULAR PROTEINS; HUNTINGTIN; HUNTINGTON DISEASE; NEURONAL CELL; POST-TRANSLATIONAL MODIFICATIONS; PROTEIN FRAGMENTS;

PROTEINS;

HUNTINGTIN; HUNTINGTIN EXON1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DROSOPHILA; EYE; GENE REPRESSION; HUNTINGTON CHOREA; LYSOSOME; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN GLYCOSYLATION; PROTEIN METABOLISM; VISUAL IMPAIRMENT;

AUTOPHAGY; NEURODEGENERATIVE DISEASES; O-GLCNACYLATION; POST-TRANSLATIONAL MODIFICATION; PROTEIN AGGREGATION;

ACYLATION; ANIMALS; AUTOPHAGY; CYTOTOXINS; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; HUNTINGTON DISEASE; IMAGINAL DISCS; MICE; MICROTUBULE-ASSOCIATED PROTEINS; NEURONS;

EID: 84900424968     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.553321     Document Type: Article

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