Cigarette smoke exposure and hypercholesterolemia increase mitochondrial damage in cardiovascular tissues

Circulation

Volumn 105, Issue 7, 2002, Pages 849-854

  Knight Lozano, Cynthia A ^a   Young, Christal G ^a   Burow, David L ^a   Hu, Zhao Yong ^a   Uyeminami, Dale ^b   Pinkerton, Kent E ^b   Ischiropoulos, Harry ^c   Ballinger, Scott W ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

Atherosclerosis; Hypercholesterolemia; Mitochondria; Smoking

Indexed keywords

APOLIPOPROTEIN E; CHOLESTEROL; CIGARETTE SMOKE; MITOCHONDRIAL DNA; MITOCHONDRIAL ENZYME; PROTEIN; TOBACCO SMOKE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CARDIOVASCULAR SYSTEM; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA DAMAGE; ENZYME ACTIVITY; EXPOSURE; HYPERCHOLESTEROLEMIA; MALE; MOUSE; NITRATION; NONHUMAN; OXIDATIVE STRESS; PASSIVE SMOKING; PRIORITY JOURNAL; RISK FACTOR;

ANIMALS; AORTA; ARTERIOSCLEROSIS; CARDIOVASCULAR SYSTEM; DISEASE PROGRESSION; DNA DAMAGE; DNA, MITOCHONDRIAL; HYPERCHOLESTEROLEMIA; INHALATION EXPOSURE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA, HEART; MITOCHONDRIAL ADP, ATP TRANSLOCASES; MYOCARDIUM; OXIDATIVE STRESS; RISK FACTORS; SUPEROXIDE DISMUTASE; TOBACCO SMOKE POLLUTION; TYROSINE;

EID: 0037133157     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/hc0702.103977     Document Type: Article

References (30)

1. Environmental tobacco smoke and coronary heart disease in the American Cancer Society CPS-II cohort
2. Passive smoking is associated with impaired endothelium dependent dilation in healthy young adults
3. Early endothelial dysfunction in adults at risk from atherosclerosis: Different responses to L-arginine
4. Passive smoking induces atherogenic changes in LDL
5. Reduced plasma ascorbic acid concentrations in nonsmokers regularly exposed to environmental tobacco smoke
6. Modulation of oxidant stress in vivo in chronic cigarette smokers
7. Passive smoking severely decreases platelet sensitivity to antiaggregatory prostaglandins
8. Inhalation of steady-state sidestream smoke from one cigarette promotes atherosclerotic plaque development
9. Passive smoking and heart disease: Epidemiology, physiology, and biochemistry
10. Passive smoking and heart disease
11. Hydrogen peroxide and peroxynitrite induced mitochondrial DNA damage and dysfunction in vascular endothelial and smooth muscle cells
12. Mitochondrial adenine nucleotide translocase is modified oxidatively during aging
13. Peroxynitrite-mediated inactivation of manganese superoxide dismutase involves nitration and oxidation of critical tyrosine residues
14. Direct evidence for tumor necrosis factor induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity
15. A role for reactive oxygen species in endothelial cell anoikis
16. Severe hypercholesterolemia and atherosclerosis in apolipoprotein E deficient mice created by homologous recombination in ES cells
17. Atherosclerosis in mice lacking apoE, evaluation of lesional development and progression
18. Enzymatic determination of total serum cholesterol
19. Superoxide dismutase assays
20. A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator
21. Peroxynitrite mediated tyrosine nitration catalyzed by superoxide dismutase
22. -/- mice
23. Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry
24. Nitric oxide and oxygen radicals: A question of balance
25. Inhibition of mitochondrial electron transport by peroxynitrite
26. Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts
27. Mitochondrial creatinine kinase is a prime target of peroxynitrite-induced modification and inactivation
28. Lipid peroxidation in mitochondria
29. Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice