-
1
-
-
0024368359
-
Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype
-
Ando DG, Clayton J, Kono D, Urban JL, Sercarz EE (1989) Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype. Cell Immunol 124(1):132–143. doi:10.1016/0008-8749(89)90117-2
-
(1989)
Cell Immunol
, vol.124
, Issue.1
, pp. 132-143
-
-
Ando, D.G.1
Clayton, J.2
Kono, D.3
Urban, J.L.4
Sercarz, E.E.5
-
3
-
-
84906841402
-
Neutrophils mediate blood–spinal cord barrier disruption in demyelinating neuroinflammatory diseases
-
Aubé B, Lévesque SA, Paré A, Chamma É, Kébir H, Gorina R, Lécuyer M-A, Alvarez JI, De Koninck Y, Engelhardt B, Prat A, Côté D, Lacroix S (2014) Neutrophils mediate blood–spinal cord barrier disruption in demyelinating neuroinflammatory diseases. J Immunol 193(5):2438–2454. doi:10.4049/jimmunol.1400401
-
(2014)
J Immunol
, vol.193
, Issue.5
, pp. 2438-2454
-
-
Aubé, B.1
Lévesque, S.A.2
Paré, A.3
Chamma, É.4
Kébir, H.5
Gorina, R.6
Lécuyer, M.-A.7
Alvarez, J.I.8
De Koninck, Y.9
Engelhardt, B.10
Prat, A.11
Côté, D.12
Lacroix, S.13
-
4
-
-
0000814155
-
Nucleotide sequence of human monocyte interleukin 1 precursor cDNA
-
COI: 1:CAS:528:DyaL2MXht1KnurY%3D, PID: 6083565
-
Auron PE, Webb AC, Rosenwasser LJ, Mucci SF, Rich A, Wolff SM, Dinarello CA (1984) Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. Proc Natl Acad Sci USA 81(24):7907–7911
-
(1984)
Proc Natl Acad Sci USA
, vol.81
, Issue.24
, pp. 7907-7911
-
-
Auron, P.E.1
Webb, A.C.2
Rosenwasser, L.J.3
Mucci, S.F.4
Rich, A.5
Wolff, S.M.6
Dinarello, C.A.7
-
5
-
-
84929273267
-
Cytokine-producing microglia have an altered beta-amyloid load in aged APP/PS1 Tg mice
-
COI: 1:CAS:528:DC%2BC2MXksF2msr4%3D, PID: 25774009
-
Babcock AA, Ilkjær L, Clausen BH, Villadsen B, Dissing-Olesen L, Bendixen AT, Lyck L, Lambertsen KL, Finsen B (2015) Cytokine-producing microglia have an altered beta-amyloid load in aged APP/PS1 Tg mice. Brain Behav Immun 48:86–101
-
(2015)
Brain Behav Immun
, vol.48
, pp. 86-101
-
-
Babcock, A.A.1
Ilkjær, L.2
Clausen, B.H.3
Villadsen, B.4
Dissing-Olesen, L.5
Bendixen, A.T.6
Lyck, L.7
Lambertsen, K.L.8
Finsen, B.9
-
6
-
-
85015637535
-
Therapeutic targeting of the pathological triad of extrasynaptic NMDA receptor signaling in neurodegenerations
-
COI: 1:CAS:528:DC%2BC2sXhtV2ju7jE, PID: 28209726
-
Bading H (2017) Therapeutic targeting of the pathological triad of extrasynaptic NMDA receptor signaling in neurodegenerations. J Exp Med 214(3):569
-
(2017)
J Exp Med
, vol.214
, Issue.3
, pp. 569
-
-
Bading, H.1
-
7
-
-
22144457454
-
The Ins2Akita mouse as a model of early retinal complications in diabetes
-
Barber AJ, Antonetti DA, Kern TS, Reiter CEN, Soans RS, Krady JK, Levison SW, Gardner TW, Bronson SK (2005) The Ins2Akita mouse as a model of early retinal complications in diabetes. Invest Ophthalmol Vis Sci 46(6):2210–2218. doi:10.1167/iovs.04-1340
-
(2005)
Invest Ophthalmol Vis Sci
, vol.46
, Issue.6
, pp. 2210-2218
-
-
Barber, A.J.1
Antonetti, D.A.2
Kern, T.S.3
Reiter, C.E.N.4
Soans, R.S.5
Krady, J.K.6
Levison, S.W.7
Gardner, T.W.8
Bronson, S.K.9
-
8
-
-
85002412707
-
Cytokine networks in neuroinflammation
-
Becher B, Spath S, Goverman J (2017) Cytokine networks in neuroinflammation. Nat Rev Immunol 17(1):49–59. doi:10.1038/nri.2016.123
-
(2017)
Nat Rev Immunol
, vol.17
, Issue.1
, pp. 49-59
-
-
Becher, B.1
Spath, S.2
Goverman, J.3
-
9
-
-
24144453087
-
Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism
-
Block ML, Hong J-S (2005) Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism. Prog Neurobiol 76(2):77–98. doi:10.1016/j.pneurobio.2005.06.004
-
(2005)
Prog Neurobiol
, vol.76
, Issue.2
, pp. 77-98
-
-
Block, M.L.1
Hong, J.-S.2
-
10
-
-
0029417080
-
Interleukin-1β and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer’s and de novo Parkinson’s disease patients
-
Blum-Degena D, Müller T, Kuhn W, Gerlach M, Przuntek H, Riederer P (1995) Interleukin-1β and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer’s and de novo Parkinson’s disease patients. Neurosci Lett 202(1):17–20
-
(1995)
Neurosci Lett
, vol.202
, Issue.1
, pp. 17-20
-
-
Blum-Degena, D.1
Müller, T.2
Kuhn, W.3
Gerlach, M.4
Przuntek, H.5
Riederer, P.6
-
11
-
-
63149114677
-
Glatiramer acetate increases IL-1 receptor antagonist but decreases T cell-induced IL-1β in human monocytes and multiple sclerosis
-
Burger D, Molnarfi N, Weber MS, Brandt KJ, Benkhoucha M, Gruaz L, Chofflon M, Zamvil SS, Lalive PH (2009) Glatiramer acetate increases IL-1 receptor antagonist but decreases T cell-induced IL-1β in human monocytes and multiple sclerosis. Proc Natl Acad Sci USA 106(11):4355–4359. doi:10.1073/pnas.0812183106
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.11
, pp. 4355-4359
-
-
Burger, D.1
Molnarfi, N.2
Weber, M.S.3
Brandt, K.J.4
Benkhoucha, M.5
Gruaz, L.6
Chofflon, M.7
Zamvil, S.S.8
Lalive, P.H.9
-
12
-
-
85007436444
-
Expression of IL-1beta in rhesus EAE and MS lesions is mainly induced in the CNS itself
-
Burm SM, Peferoen LA, Zuiderwijk-Sick EA, Haanstra KG, t Hart BA, van der Valk P, Amor S, Bauer J, Bajramovic JJ (2016) Expression of IL-1beta in rhesus EAE and MS lesions is mainly induced in the CNS itself. J Neuroinflammation 13(1):138. doi:10.1186/s12974-016-0605-8
-
(2016)
J Neuroinflammation
, vol.13
, Issue.1
, pp. 138
-
-
Burm, S.M.1
Peferoen, L.A.2
Zuiderwijk-Sick, E.A.3
Haanstra, K.G.4
t Hart, B.A.5
van der Valk, P.6
Amor, S.7
Bauer, J.8
Bajramovic, J.J.9
-
13
-
-
0028178004
-
Brain interleukin-1 beta in Alzheimer’s disease and vascular dementia
-
COI: 1:STN:280:DyaK2c3ns1Klsg%3D%3D, PID: 8007743
-
Cacabelos R, Alvarez X, Fernandez-Novoa L, Franco A, Mangues R, Pellicer A, Nishimura T (1994) Brain interleukin-1 beta in Alzheimer’s disease and vascular dementia. Methods Find Exp Clin Pharmacol 16(2):141–151
-
(1994)
Methods Find Exp Clin Pharmacol
, vol.16
, Issue.2
, pp. 141-151
-
-
Cacabelos, R.1
Alvarez, X.2
Fernandez-Novoa, L.3
Franco, A.4
Mangues, R.5
Pellicer, A.6
Nishimura, T.7
-
14
-
-
0028941871
-
The adhesion molecule and cytokine profile of multiple sclerosis lesions
-
Cannella B, Raine CS (1995) The adhesion molecule and cytokine profile of multiple sclerosis lesions. Ann Neurol 37(4):424–435. doi:10.1002/ana.410370404
-
(1995)
Ann Neurol
, vol.37
, Issue.4
, pp. 424-435
-
-
Cannella, B.1
Raine, C.S.2
-
15
-
-
84946204508
-
Disruption of fractalkine signaling leads to microglial activation and neuronal damage in the diabetic retina
-
Cardona SM, Mendiola AS, Yang Y-C, Adkins SL, Torres V, Cardona AE (2015) Disruption of fractalkine signaling leads to microglial activation and neuronal damage in the diabetic retina. ASN Neuro 7(5). doi:10.1177/1759091415608204
-
(2015)
ASN Neuro
, vol.7
, Issue.5
-
-
Cardona, S.M.1
Mendiola, A.S.2
Yang, Y.-C.3
Adkins, S.L.4
Torres, V.5
Cardona, A.E.6
-
16
-
-
0034531053
-
Effect of cyclosporin-A on the blood–retinal barrier permeability in streptozotocin-induced diabetes
-
Carmo A, Cunha-Vaz JG, Carvalho AP, Lopes MC (2000) Effect of cyclosporin-A on the blood–retinal barrier permeability in streptozotocin-induced diabetes. Mediat Inflamm 9(5):243–248. doi:10.1080/09629350020025764
-
(2000)
Mediat Inflamm
, vol.9
, Issue.5
, pp. 243-248
-
-
Carmo, A.1
Cunha-Vaz, J.G.2
Carvalho, A.P.3
Lopes, M.C.4
-
17
-
-
0036847841
-
Microglia as liaisons between the immune and central nervous systems: functional implications for multiple sclerosis
-
Carson MJ (2002) Microglia as liaisons between the immune and central nervous systems: functional implications for multiple sclerosis. Glia 40(2):218–231. doi:10.1002/glia.10145
-
(2002)
Glia
, vol.40
, Issue.2
, pp. 218-231
-
-
Carson, M.J.1
-
18
-
-
84864386088
-
Effects of gevokizumab on glycemia and inflammatory markers in type 2 diabetes
-
Cavelti-Weder C, Babians-Brunner A, Keller C, Stahel MA, Kurz-Levin M, Zayed H, Solinger AM, Mandrup-Poulsen T, Dinarello CA, Donath MY (2012) Effects of gevokizumab on glycemia and inflammatory markers in type 2 diabetes. Diabetes Care 35(8):1654–1662. doi:10.2337/dc11-2219
-
(2012)
Diabetes Care
, vol.35
, Issue.8
, pp. 1654-1662
-
-
Cavelti-Weder, C.1
Babians-Brunner, A.2
Keller, C.3
Stahel, M.A.4
Kurz-Levin, M.5
Zayed, H.6
Solinger, A.M.7
Mandrup-Poulsen, T.8
Dinarello, C.A.9
Donath, M.Y.10
-
19
-
-
84885105118
-
Neuron-derived semaphorin 3A is an early inducer of vascular permeability in diabetic retinopathy via neuropilin-1
-
Cerani A, Tetreault N, Menard C, Lapalme E, Patel C, Sitaras N, Beaudoin F, Leboeuf D, De Guire V, Binet F, Dejda A, Rezende Flavio A, Miloudi K, Sapieha P (2013) Neuron-derived semaphorin 3A is an early inducer of vascular permeability in diabetic retinopathy via neuropilin-1. Cell Metab 18(4):505–518. doi:10.1016/j.cmet.2013.09.003
-
(2013)
Cell Metab
, vol.18
, Issue.4
, pp. 505-518
-
-
Cerani, A.1
Tetreault, N.2
Menard, C.3
Lapalme, E.4
Patel, C.5
Sitaras, N.6
Beaudoin, F.7
Leboeuf, D.8
De Guire, V.9
Binet, F.10
Dejda, A.11
Rezende Flavio, A.12
Miloudi, K.13
Sapieha, P.14
-
20
-
-
84946398388
-
+ microglia reduce Abeta plaque deposition during IL-1beta-dependent neuroinflammation
-
+ microglia reduce Abeta plaque deposition during IL-1beta-dependent neuroinflammation. J Neuroinflammation 12:203. doi:10.1186/s12974-015-0411-8
-
(2015)
J Neuroinflammation
, vol.12
, pp. 203
-
-
Cherry, J.D.1
Olschowka, J.A.2
O’Banion, M.K.3
-
21
-
-
64049089798
-
Critical regulation of early Th17 cell differentiation by interleukin-1 signaling
-
Chung Y, Chang SH, Martinez GJ, Yang XO, Nurieva R, Kang HS, Ma L, Watowich SS, Jetten AM, Tian Q, Dong C (2009) Critical regulation of early Th17 cell differentiation by interleukin-1 signaling. Immunity 30(4):576–587. doi:10.1016/j.immuni.2009.02.007
-
(2009)
Immunity
, vol.30
, Issue.4
, pp. 576-587
-
-
Chung, Y.1
Chang, S.H.2
Martinez, G.J.3
Yang, X.O.4
Nurieva, R.5
Kang, H.S.6
Ma, L.7
Watowich, S.S.8
Jetten, A.M.9
Tian, Q.10
Dong, C.11
-
22
-
-
79956116032
-
ROR[gamma]t drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation
-
Codarri L, Gyulveszi G, Tosevski V, Hesske L, Fontana A, Magnenat L, Suter T, Becher B (2011) ROR[gamma]t drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation. Nat Immunol 12(6):560–567. doi:10.1038/ni.2027
-
(2011)
Nat Immunol
, vol.12
, Issue.6
, pp. 560-567
-
-
Codarri, L.1
Gyulveszi, G.2
Tosevski, V.3
Hesske, L.4
Fontana, A.5
Magnenat, L.6
Suter, T.7
Becher, B.8
-
23
-
-
84937113148
-
Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques
-
Condello C, Yuan P, Schain A, Grutzendler J (2015) Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques. Nat Commun 6:6176. doi:10.1038/ncomms7176
-
(2015)
Nat Commun
, vol.6
, pp. 6176
-
-
Condello, C.1
Yuan, P.2
Schain, A.3
Grutzendler, J.4
-
24
-
-
84941735780
-
+ monocytes and licenses autoimmunity
-
+ monocytes and licenses autoimmunity. Immunity 43(3):502–514. doi:10.1016/j.immuni.2015.08.010
-
(2015)
Immunity
, vol.43
, Issue.3
, pp. 502-514
-
-
Croxford, A.L.1
Lanzinger, M.2
Hartmann, F.J.3
Schreiner, B.4
Mair, F.5
Pelczar, P.6
Clausen, B.E.7
Jung, S.8
Greter, M.9
Becher, B.10
-
25
-
-
84869178487
-
Microglia and neurodegeneration: the role of systemic inflammation
-
Cunningham C (2013) Microglia and neurodegeneration: the role of systemic inflammation. Glia 61(1):71–90. doi:10.1002/glia.22350
-
(2013)
Glia
, vol.61
, Issue.1
, pp. 71-90
-
-
Cunningham, C.1
-
26
-
-
85016586166
-
Young microglia restore amyloid plaque clearance of aged microglia
-
Daria A, Colombo A, Llovera G, Hampel H, Willem M, Liesz A, Haass C, Tahirovic S (2016) Young microglia restore amyloid plaque clearance of aged microglia. EMBO J. doi:10.15252/embj.201694591
-
(2016)
EMBO J
-
-
Daria, A.1
Colombo, A.2
Llovera, G.3
Hampel, H.4
Willem, M.5
Liesz, A.6
Haass, C.7
Tahirovic, S.8
-
27
-
-
84859715302
-
Fibrinogen as a key regulator of inflammation in disease
-
Davalos D, Akassoglou K (2012) Fibrinogen as a key regulator of inflammation in disease. Semin Immunopathol 34(1):43–62. doi:10.1007/s00281-011-0290-8
-
(2012)
Semin Immunopathol
, vol.34
, Issue.1
, pp. 43-62
-
-
Davalos, D.1
Akassoglou, K.2
-
28
-
-
79953046719
-
The inflammasome NLRs in immunity, inflammation, and associated diseases
-
COI: 1:CAS:528:DC%2BC3MXltlKnsLY%3D, PID: 21219188
-
Davis BK, Wen H, Ting JP (2011) The inflammasome NLRs in immunity, inflammation, and associated diseases. Annu Rev Immunol 29:707
-
(2011)
Annu Rev Immunol
, vol.29
, pp. 707
-
-
Davis, B.K.1
Wen, H.2
Ting, J.P.3
-
29
-
-
0035999548
-
Production of IL-1β and IL-1Ra as risk factors for susceptibility and progression of relapse-onset multiple sclerosis
-
de Jong BA, Huizinga TWJ, Bollen ELEM, Uitdehaag BMJ, Bosma GPT, van Buchem MA, Remarque EJ, Burgmans ACS, Kalkers NF, Polman CH, Westendorp RGJ (2002) Production of IL-1β and IL-1Ra as risk factors for susceptibility and progression of relapse-onset multiple sclerosis. J Neuroimmunol 126(1–2):172–179. doi:10.1016/S0165-5728(02)00056-5
-
(2002)
J Neuroimmunol
, vol.126
, Issue.1-2
, pp. 172-179
-
-
de Jong, B.A.1
Huizinga, T.W.J.2
Bollen, E.L.E.M.3
Uitdehaag, B.M.J.4
Bosma, G.P.T.5
van Buchem, M.A.6
Remarque, E.J.7
Burgmans, A.C.S.8
Kalkers, N.F.9
Polman, C.H.10
Westendorp, R.G.J.11
-
30
-
-
33845546564
-
Determination of vitreous interleukin-1 (IL-1) and tumour necrosis factor (TNF) levels in proliferative diabetic retinopathy
-
Demircan N, Safran BG, Soylu M, Ozcan AA, Sizmaz S (2005) Determination of vitreous interleukin-1 (IL-1) and tumour necrosis factor (TNF) levels in proliferative diabetic retinopathy. Eye 20(12):1366–1369. doi:10.1038/sj.eye.6702138
-
(2005)
Eye
, vol.20
, Issue.12
, pp. 1366-1369
-
-
Demircan, N.1
Safran, B.G.2
Soylu, M.3
Ozcan, A.A.4
Sizmaz, S.5
-
31
-
-
84940453103
-
Immunopathology of multiple sclerosis
-
Dendrou CA, Fugger L, Friese MA (2015) Immunopathology of multiple sclerosis. Nat Rev Immunol 15(9):545–558. doi:10.1038/nri3871
-
(2015)
Nat Rev Immunol
, vol.15
, Issue.9
, pp. 545-558
-
-
Dendrou, C.A.1
Fugger, L.2
Friese, M.A.3
-
32
-
-
62649139025
-
Immunological and inflammatory functions of the interleukin-1 family
-
Dinarello CA (2009) Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol 27(1):519–550. doi:10.1146/annurev.immunol.021908.132612
-
(2009)
Annu Rev Immunol
, vol.27
, Issue.1
, pp. 519-550
-
-
Dinarello, C.A.1
-
33
-
-
79953813107
-
Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
-
Dinarello CA (2011) Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. Blood 117(14):3720–3732. doi:10.1182/blood-2010-07-273417
-
(2011)
Blood
, vol.117
, Issue.14
, pp. 3720-3732
-
-
Dinarello, C.A.1
-
34
-
-
84864545087
-
Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
-
Dinarello CA, Simon A, van der Meer JWM (2012) Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases. Nat Rev Drug Discov 11(8):633–652. doi:10.1038/nrd3800
-
(2012)
Nat Rev Drug Discov
, vol.11
, Issue.8
, pp. 633-652
-
-
Dinarello, C.A.1
Simon, A.2
van der Meer, J.W.M.3
-
35
-
-
85009810559
-
Postprandial macrophage-derived IL-1[beta] stimulates insulin, and both synergistically promote glucose disposal and inflammation
-
Dror E, Dalmas E, Meier DT, Wueest S, Thevenet J, Thienel C, Timper K, Nordmann TM, Traub S, Schulze F, Item F, Vallois D, Pattou F, Kerr-Conte J, Lavallard V, Berney T, Thorens B, Konrad D, Boni-Schnetzler M, Donath MY (2017) Postprandial macrophage-derived IL-1[beta] stimulates insulin, and both synergistically promote glucose disposal and inflammation. Nat Immunol 18(3):283–292. doi:10.1038/ni.3659
-
(2017)
Nat Immunol
, vol.18
, Issue.3
, pp. 283-292
-
-
Dror, E.1
Dalmas, E.2
Meier, D.T.3
Wueest, S.4
Thevenet, J.5
Thienel, C.6
Timper, K.7
Nordmann, T.M.8
Traub, S.9
Schulze, F.10
Item, F.11
Vallois, D.12
Pattou, F.13
Kerr-Conte, J.14
Lavallard, V.15
Berney, T.16
Thorens, B.17
Konrad, D.18
Boni-Schnetzler, M.19
Donath, M.Y.20
more..
-
36
-
-
84885357617
-
Photoreceptor cells are major contributors to diabetes-induced oxidative stress and local inflammation in the retina
-
Du Y, Veenstra A, Palczewski K, Kern TS (2013) Photoreceptor cells are major contributors to diabetes-induced oxidative stress and local inflammation in the retina. Proc Natl Acad Sci USA 110(41):16586–16591. doi:10.1073/pnas.1314575110
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.41
, pp. 16586-16591
-
-
Du, Y.1
Veenstra, A.2
Palczewski, K.3
Kern, T.S.4
-
37
-
-
84982757688
-
Subretinal mononuclear phagocytes induce cone segment loss via IL-1β
-
Eandi CM, Messance HC, Augustin S, Dominguez E, Lavalette S, Forster V, Hu SJ, Siquieros L, Craft CM, Sahel J-A (2016) Subretinal mononuclear phagocytes induce cone segment loss via IL-1β. eLife 5:e16490. doi:10.7554/eLife.16490
-
(2016)
eLife
, vol.5
-
-
Eandi, C.M.1
Messance, H.C.2
Augustin, S.3
Dominguez, E.4
Lavalette, S.5
Forster, V.6
Hu, S.J.7
Siquieros, L.8
Craft, C.M.9
Sahel, J.-A.10
-
38
-
-
79956152607
-
The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF
-
El-Behi M, Ciric B, Dai H, Yan Y, Cullimore M, Safavi F, Zhang G-X, Dittel BN, Rostami A (2011) The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF. Nat Immunol 12(6):568–575. doi:10.1038/ni.2031
-
(2011)
Nat Immunol
, vol.12
, Issue.6
, pp. 568-575
-
-
El-Behi, M.1
Ciric, B.2
Dai, H.3
Yan, Y.4
Cullimore, M.5
Safavi, F.6
Zhang, G.-X.7
Dittel, B.N.8
Rostami, A.9
-
39
-
-
84956596401
-
The pathogenic role of the inflammasome in neurodegenerative diseases
-
Freeman LC, Ting JP (2016) The pathogenic role of the inflammasome in neurodegenerative diseases. J Neurochem 136(Suppl 1):29–38. doi:10.1111/jnc.13217
-
(2016)
J Neurochem
, vol.136
, pp. 29-38
-
-
Freeman, L.C.1
Ting, J.P.2
-
40
-
-
84966429058
-
IL-33 ameliorates Alzheimer’s disease-like pathology and cognitive decline
-
Fu AKY, Hung K-W, Yuen MYF, Zhou X, Mak DSY, Chan ICW, Cheung TH, Zhang B, Fu W-Y, Liew FY, Ip NY (2016) IL-33 ameliorates Alzheimer’s disease-like pathology and cognitive decline. Proc Natl Acad Sci USA 113(19):E2705–E2713. doi:10.1073/pnas.1604032113
-
(2016)
Proc Natl Acad Sci USA
, vol.113
, Issue.19
, pp. E2705-E2713
-
-
Fu, A.K.Y.1
Hung, K.-W.2
Yuen, M.Y.F.3
Zhou, X.4
Mak, D.S.Y.5
Chan, I.C.W.6
Cheung, T.H.7
Zhang, B.8
Fu, W.-Y.9
Liew, F.Y.10
Ip, N.Y.11
-
41
-
-
0033198269
-
Caspase-1 regulates the inflammatory process leading to autoimmune demyelination
-
COI: 1:CAS:528:DyaK1MXls1Krs7o%3D, PID: 10452974
-
Furlan R, Martino G, Galbiati F, Poliani PL, Smiroldo S, Bergami A, Desina G, Comi G, Flavell R, Su MS, Adorini L (1999) Caspase-1 regulates the inflammatory process leading to autoimmune demyelination. J Immunol 163(5):2403–2409
-
(1999)
J Immunol
, vol.163
, Issue.5
, pp. 2403-2409
-
-
Furlan, R.1
Martino, G.2
Galbiati, F.3
Poliani, P.L.4
Smiroldo, S.5
Bergami, A.6
Desina, G.7
Comi, G.8
Flavell, R.9
Su, M.S.10
Adorini, L.11
-
42
-
-
78149360132
-
Fate mapping analysis reveals that adult microglia derive from primitive macrophages
-
Ginhoux F, Greter M, Leboeuf M, Nandi S, See P, Gokhan S, Mehler MF, Conway SJ, Ng LG, Stanley ER, Samokhvalov IM, Merad M (2010) Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science 330(6005):841. doi:10.1126/science.1194637
-
(2010)
Science
, vol.330
, Issue.6005
, pp. 841
-
-
Ginhoux, F.1
Greter, M.2
Leboeuf, M.3
Nandi, S.4
See, P.5
Gokhan, S.6
Mehler, M.F.7
Conway, S.J.8
Ng, L.G.9
Stanley, E.R.10
Samokhvalov, I.M.11
Merad, M.12
-
43
-
-
74949127437
-
Formation and maintenance of Alzheimer’s disease [beta]-amyloid plaques in the absence of microglia
-
Grathwohl SA, Kalin RE, Bolmont T, Prokop S, Winkelmann G, Kaeser SA, Odenthal J, Radde R, Eldh T, Gandy S, Aguzzi A, Staufenbiel M, Mathews PM, Wolburg H, Heppner FL, Jucker M (2009) Formation and maintenance of Alzheimer’s disease [beta]-amyloid plaques in the absence of microglia. Nat Neurosci 12(11):1361–1363. doi:10.1038/nn.2432
-
(2009)
Nat Neurosci
, vol.12
, Issue.11
, pp. 1361-1363
-
-
Grathwohl, S.A.1
Kalin, R.E.2
Bolmont, T.3
Prokop, S.4
Winkelmann, G.5
Kaeser, S.A.6
Odenthal, J.7
Radde, R.8
Eldh, T.9
Gandy, S.10
Aguzzi, A.11
Staufenbiel, M.12
Mathews, P.M.13
Wolburg, H.14
Heppner, F.L.15
Jucker, M.16
-
44
-
-
84952922436
-
Retinal failure in diabetes: a feature of retinal sensory neuropathy
-
Gray EJ, Gardner TW (2015) Retinal failure in diabetes: a feature of retinal sensory neuropathy. Curr Diabetes Rep 15(12):107. doi:10.1007/s11892-015-0683-5
-
(2015)
Curr Diabetes Rep
, vol.15
, Issue.12
, pp. 107
-
-
Gray, E.J.1
Gardner, T.W.2
-
45
-
-
84952977873
-
Myelin-specific T cells induce interleukin-1beta expression in lesion-reactive microglial-like cells in zones of axonal degeneration
-
Grebing M, Nielsen HH, Fenger CD, Jensen K, von Linstow CU, Clausen BH, Söderman M, Lambertsen KL, Thomassen M, Kruse TA (2016) Myelin-specific T cells induce interleukin-1beta expression in lesion-reactive microglial-like cells in zones of axonal degeneration. Glia 64(3):407–424. doi:10.1002/glia.22937
-
(2016)
Glia
, vol.64
, Issue.3
, pp. 407-424
-
-
Grebing, M.1
Nielsen, H.H.2
Fenger, C.D.3
Jensen, K.4
von Linstow, C.U.5
Clausen, B.H.6
Söderman, M.7
Lambertsen, K.L.8
Thomassen, M.9
Kruse, T.A.10
-
46
-
-
0001360461
-
Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease
-
COI: 1:STN:280:DyaK3c%2FhslGhug%3D%3D, PID: 2529544
-
Griffin W, Stanley L, Ling C, White L, MacLeod V, Perrot L, White C, Araoz C (1989) Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease. Proc Natl Acad Sci USA 86(19):7611–7615
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, Issue.19
, pp. 7611-7615
-
-
Griffin, W.1
Stanley, L.2
Ling, C.3
White, L.4
MacLeod, V.5
Perrot, L.6
White, C.7
Araoz, C.8
-
47
-
-
84937010766
-
The role of microglia in diabetic retinopathy
-
Grigsby JG, Cardona SM, Pouw CE, Muniz A, Mendiola AS, Tsin AT, Allen DM, Cardona AE (2014) The role of microglia in diabetic retinopathy. J Ophthalmol 2014:705783. doi:10.1155/2014/705783
-
(2014)
J Ophthalmol
, vol.2014
, pp. 705783
-
-
Grigsby, J.G.1
Cardona, S.M.2
Pouw, C.E.3
Muniz, A.4
Mendiola, A.S.5
Tsin, A.T.6
Allen, D.M.7
Cardona, A.E.8
-
48
-
-
79951740151
-
Type I interferon inhibits interleukin-1 production and inflammasome activation
-
Guarda G, Braun M, Staehli F, Tardivel A, Mattmann C, Förster I, Farlik M, Decker T, Du Pasquier Renaud A, Romero P, Tschopp J (2011) Type I interferon inhibits interleukin-1 production and inflammasome activation. Immunity 34(2):213–223. doi:10.1016/j.immuni.2011.02.006
-
(2011)
Immunity
, vol.34
, Issue.2
, pp. 213-223
-
-
Guarda, G.1
Braun, M.2
Staehli, F.3
Tardivel, A.4
Mattmann, C.5
Förster, I.6
Farlik, M.7
Decker, T.8
Du Pasquier, R.A.9
Romero, P.10
Tschopp, J.11
-
49
-
-
74649086985
-
The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation
-
Gulen MF, Kang Z, Bulek K, Youzhong W, Kim TW, Chen Y, Altuntas CZ, Sass Bak-Jensen K, McGeachy MJ, Do J-S, Xiao H, Delgoffe GM, Min B, Powell JD, Tuohy VK, Cua DJ, Li X (2010) The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation. Immunity 32(1):54–66. doi:10.1016/j.immuni.2009.12.003
-
(2010)
Immunity
, vol.32
, Issue.1
, pp. 54-66
-
-
Gulen, M.F.1
Kang, Z.2
Bulek, K.3
Youzhong, W.4
Kim, T.W.5
Chen, Y.6
Altuntas, C.Z.7
Sass Bak-Jensen, K.8
McGeachy, M.J.9
Do, J.-S.10
Xiao, H.11
Delgoffe, G.M.12
Min, B.13
Powell, J.D.14
Tuohy, V.K.15
Cua, D.J.16
Li, X.17
-
50
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-[beta]
-
Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, Reinheckel T, Fitzgerald KA, Latz E, Moore KJ, Golenbock DT (2008) The NALP3 inflammasome is involved in the innate immune response to amyloid-[beta]. Nat Immunol 9(8):857–865. doi:10.1038/ni.1636
-
(2008)
Nat Immunol
, vol.9
, Issue.8
, pp. 857-865
-
-
Halle, A.1
Hornung, V.2
Petzold, G.C.3
Stewart, C.R.4
Monks, B.G.5
Reinheckel, T.6
Fitzgerald, K.A.7
Latz, E.8
Moore, K.J.9
Golenbock, D.T.10
-
51
-
-
84862649049
-
Toll-like receptor (TLR) and inflammasome actions in the central nervous system
-
COI: 1:CAS:528:DC%2BC38XlvFyrtbw%3D, PID: 22521509
-
Hanamsagar R, Hanke ML, Kielian T (2012) Toll-like receptor (TLR) and inflammasome actions in the central nervous system. Trends Immunol 33(7):333–342
-
(2012)
Trends Immunol
, vol.33
, Issue.7
, pp. 333-342
-
-
Hanamsagar, R.1
Hanke, M.L.2
Kielian, T.3
-
52
-
-
84873087532
-
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
-
Heneka MT, Kummer MP, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng T-C, Gelpi E, Halle A, Korte M, Latz E, Golenbock DT (2013) NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice. Nature 493(7434):674–678. doi:10.1038/nature11729
-
(2013)
Nature
, vol.493
, Issue.7434
, pp. 674-678
-
-
Heneka, M.T.1
Kummer, M.P.2
Stutz, A.3
Delekate, A.4
Schwartz, S.5
Vieira-Saecker, A.6
Griep, A.7
Axt, D.8
Remus, A.9
Tzeng, T.-C.10
Gelpi, E.11
Halle, A.12
Korte, M.13
Latz, E.14
Golenbock, D.T.15
-
53
-
-
84926370173
-
Neuroinflammation in Alzheimer’s disease
-
Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, Jacobs AH, Wyss-Coray T, Vitorica J, Ransohoff RM, Herrup K, Frautschy SA, Finsen B, Brown GC, Verkhratsky A, Yamanaka K, Koistinaho J, Latz E, Halle A, Petzold GC, Town T, Morgan D, Shinohara ML, Perry VH, Holmes C, Bazan NG, Brooks DJ, Hunot S, Joseph B, Deigendesch N, Garaschuk O, Boddeke E, Dinarello CA, Breitner JC, Cole GM, Golenbock DT, Kummer MP (2015) Neuroinflammation in Alzheimer’s disease. Lancet Neurol 14(4):388–405. doi:10.1016/s1474-4422(15)70016-5
-
(2015)
Lancet Neurol
, vol.14
, Issue.4
, pp. 388-405
-
-
Heneka, M.T.1
Carson, M.J.2
El Khoury, J.3
Landreth, G.E.4
Brosseron, F.5
Feinstein, D.L.6
Jacobs, A.H.7
Wyss-Coray, T.8
Vitorica, J.9
Ransohoff, R.M.10
Herrup, K.11
Frautschy, S.A.12
Finsen, B.13
Brown, G.C.14
Verkhratsky, A.15
Yamanaka, K.16
Koistinaho, J.17
Latz, E.18
Halle, A.19
Petzold, G.C.20
Town, T.21
Morgan, D.22
Shinohara, M.L.23
Perry, V.H.24
Holmes, C.25
Bazan, N.G.26
Brooks, D.J.27
Hunot, S.28
Joseph, B.29
Deigendesch, N.30
Garaschuk, O.31
Boddeke, E.32
Dinarello, C.A.33
Breitner, J.C.34
Cole, G.M.35
Golenbock, D.T.36
Kummer, M.P.37
more..
-
54
-
-
84929921146
-
Immune attack: the role of inflammation in Alzheimer disease
-
Heppner FL, Ransohoff RM, Becher B (2015) Immune attack: the role of inflammation in Alzheimer disease. Nat Rev Neurosci 16(6):358–372. doi:10.1038/nrn3880
-
(2015)
Nat Rev Neurosci
, vol.16
, Issue.6
, pp. 358-372
-
-
Heppner, F.L.1
Ransohoff, R.M.2
Becher, B.3
-
55
-
-
70349570588
-
Systemic inflammation and disease progression in Alzheimer disease
-
Holmes C, Cunningham C, Zotova E, Woolford J, Dean C, Kerr S, Culliford D, Perry VH (2009) Systemic inflammation and disease progression in Alzheimer disease. Neurology 73(10):768–774. doi:10.1212/WNL.0b013e3181b6bb95
-
(2009)
Neurology
, vol.73
, Issue.10
, pp. 768-774
-
-
Holmes, C.1
Cunningham, C.2
Zotova, E.3
Woolford, J.4
Dean, C.5
Kerr, S.6
Culliford, D.7
Perry, V.H.8
-
56
-
-
84929378436
-
Upregulation of P2RX7 in Cx3cr1-deficient mononuclear phagocytes leads to increased interleukin-1β secretion and photoreceptor neurodegeneration
-
Hu SJ, Calippe B, Lavalette S, Roubeix C, Montassar F, Housset M, Levy O, Delarasse C, Paques M, Sahel J-A, Sennlaub F, Guillonneau X (2015) Upregulation of P2RX7 in Cx3cr1-deficient mononuclear phagocytes leads to increased interleukin-1β secretion and photoreceptor neurodegeneration. J Neurosci 35(18):6987–6996. doi:10.1523/jneurosci.3955-14.2015
-
(2015)
J Neurosci
, vol.35
, Issue.18
, pp. 6987-6996
-
-
Hu, S.J.1
Calippe, B.2
Lavalette, S.3
Roubeix, C.4
Montassar, F.5
Housset, M.6
Levy, O.7
Delarasse, C.8
Paques, M.9
Sahel, J.-A.10
Sennlaub, F.11
Guillonneau, X.12
-
57
-
-
84862988248
-
NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis
-
Inoue M, Williams KL, Gunn MD, Shinohara ML (2012) NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis. Proc Natl Acad Sci USA 109(26):10480–10485. doi:10.1073/pnas.1201836109
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.26
, pp. 10480-10485
-
-
Inoue, M.1
Williams, K.L.2
Gunn, M.D.3
Shinohara, M.L.4
-
58
-
-
0025856061
-
Experimental autoimmune encephalomyelitis is exacerbated by IL-1 alpha and suppressed by soluble IL-1 receptor
-
COI: 1:CAS:528:DyaK3MXlvVWhs78%3D, PID: 1826702
-
Jacobs CA, Baker PE, Roux ER, Picha KS, Toivola B, Waugh S, Kennedy MK (1991) Experimental autoimmune encephalomyelitis is exacerbated by IL-1 alpha and suppressed by soluble IL-1 receptor. J Immunol 146(9):2983–2989
-
(1991)
J Immunol
, vol.146
, Issue.9
, pp. 2983-2989
-
-
Jacobs, C.A.1
Baker, P.E.2
Roux, E.R.3
Picha, K.S.4
Toivola, B.5
Waugh, S.6
Kennedy, M.K.7
-
59
-
-
73349109145
-
Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes
-
Jäger A, Dardalhon V, Sobel RA, Bettelli E, Kuchroo VK (2009) Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes. J Immunol 183(11):7169–7177. doi:10.4049/jimmunol.0901906
-
(2009)
J Immunol
, vol.183
, Issue.11
, pp. 7169-7177
-
-
Jäger, A.1
Dardalhon, V.2
Sobel, R.A.3
Bettelli, E.4
Kuchroo, V.K.5
-
60
-
-
84924737031
-
+ inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models
-
+ inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models. J Exp Med 212(3):287–295. doi:10.1084/jem.20142322
-
(2015)
J Exp Med
, vol.212
, Issue.3
, pp. 287-295
-
-
Jay, T.R.1
Miller, C.M.2
Cheng, P.J.3
Graham, L.C.4
Bemiller, S.5
Broihier, M.L.6
Xu, G.7
Margevicius, D.8
Karlo, J.C.9
Sousa, G.L.10
Cotleur, A.C.11
Butovsky, O.12
Bekris, L.13
Staugaitis, S.M.14
Leverenz, J.B.15
Pimplikar, S.W.16
Landreth, G.E.17
Howell, G.R.18
Ransohoff, R.M.19
Lamb, B.T.20
more..
-
61
-
-
85015675626
-
Epac1 blocks NLRP3 inflammasome to reduce IL-1β in retinal endothelial cells and mouse retinal vasculature
-
Jiang Y, Liu L, Curtiss E, Steinle JJ (2017) Epac1 blocks NLRP3 inflammasome to reduce IL-1β in retinal endothelial cells and mouse retinal vasculature. Mediat Inflamm. doi:10.1155/2017/2860956
-
(2017)
Mediat Inflamm
-
-
Jiang, Y.1
Liu, L.2
Curtiss, E.3
Steinle, J.J.4
-
62
-
-
34648825492
-
Oxidative damage in the retinal mitochondria of diabetic mice: possible protection by superoxide dismutase
-
Kanwar M, Chan P-S, Kern TS, Kowluru RA (2007) Oxidative damage in the retinal mitochondria of diabetic mice: possible protection by superoxide dismutase. Invest Ophthalmol Vis Sci 48(8):3805–3811. doi:10.1167/iovs.06-1280
-
(2007)
Invest Ophthalmol Vis Sci
, vol.48
, Issue.8
, pp. 3805-3811
-
-
Kanwar, M.1
Chan, P.-S.2
Kern, T.S.3
Kowluru, R.A.4
-
63
-
-
84946149406
-
CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells
-
Kara EE, McKenzie DR, Bastow CR, Gregor CE, Fenix KA, Ogunniyi AD, Paton JC, Mack M, Pombal DR, Seillet C, Dubois B, Liston A, MacDonald KPA, Belz GT, Smyth MJ, Hill GR, Comerford I, McColl SR (2015) CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells. Nat Commun 6:8644. doi:10.1038/ncomms9644
-
(2015)
Nat Commun
, vol.6
, pp. 8644
-
-
Kara, E.E.1
McKenzie, D.R.2
Bastow, C.R.3
Gregor, C.E.4
Fenix, K.A.5
Ogunniyi, A.D.6
Paton, J.C.7
Mack, M.8
Pombal, D.R.9
Seillet, C.10
Dubois, B.11
Liston, A.12
MacDonald, K.P.A.13
Belz, G.T.14
Smyth, M.J.15
Hill, G.R.16
Comerford, I.17
McColl, S.R.18
-
64
-
-
84890843069
-
Reactive astrocytes and perivascular macrophages express NLRP3 inflammasome in active demyelinating lesions of multiple sclerosis and necrotic lesions of neuromyelitis optica and cerebral infarction
-
Kawana N, Yamamoto Y, Ishida T, Saito Y, Konno H, Arima K, Ji Satoh (2013) Reactive astrocytes and perivascular macrophages express NLRP3 inflammasome in active demyelinating lesions of multiple sclerosis and necrotic lesions of neuromyelitis optica and cerebral infarction. Clin Exp Neuroimmunol 4(3):296–304. doi:10.1111/cen3.12068
-
(2013)
Clin Exp Neuroimmunol
, vol.4
, Issue.3
, pp. 296-304
-
-
Kawana, N.1
Yamamoto, Y.2
Ishida, T.3
Saito, Y.4
Konno, H.5
Arima, K.6
Ji, S.7
-
65
-
-
84875892857
-
Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways
-
Kierdorf K, Erny D, Goldmann T, Sander V, Schulz C, Perdiguero EG, Wieghofer P, Heinrich A, Riemke P, Holscher C, Muller DN, Luckow B, Brocker T, Debowski K, Fritz G, Opdenakker G, Diefenbach A, Biber K, Heikenwalder M, Geissmann F, Rosenbauer F, Prinz M (2013) Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways. Nat Neurosci 16(3):273–280. doi:10.1038/nn.3318
-
(2013)
Nat Neurosci
, vol.16
, Issue.3
, pp. 273-280
-
-
Kierdorf, K.1
Erny, D.2
Goldmann, T.3
Sander, V.4
Schulz, C.5
Perdiguero, E.G.6
Wieghofer, P.7
Heinrich, A.8
Riemke, P.9
Holscher, C.10
Muller, D.N.11
Luckow, B.12
Brocker, T.13
Debowski, K.14
Fritz, G.15
Opdenakker, G.16
Diefenbach, A.17
Biber, K.18
Heikenwalder, M.19
Geissmann, F.20
Rosenbauer, F.21
Prinz, M.22
more..
-
66
-
-
83755183781
-
Blocking IL-1 signaling rescues cognition, attenuates tau pathology, and restores neuronal β-catenin pathway function in an Alzheimer’s disease model
-
Kitazawa M, Cheng D, Tsukamoto MR, Koike MA, Wes PD, Vasilevko V, Cribbs DH, LaFerla FM (2011) Blocking IL-1 signaling rescues cognition, attenuates tau pathology, and restores neuronal β-catenin pathway function in an Alzheimer’s disease model. J Immunol 187(12):6539–6549. doi:10.4049/jimmunol.1100620
-
(2011)
J Immunol
, vol.187
, Issue.12
, pp. 6539-6549
-
-
Kitazawa, M.1
Cheng, D.2
Tsukamoto, M.R.3
Koike, M.A.4
Wes, P.D.5
Vasilevko, V.6
Cribbs, D.H.7
LaFerla, F.M.8
-
67
-
-
84878264043
-
Photoreceptor proteins initiate microglial activation via Toll-like receptor 4 in retinal degeneration mediated by all-trans-retinal
-
Kohno H, Chen Y, Kevany BM, Pearlman E, Miyagi M, Maeda T, Palczewski K, Maeda A (2013) Photoreceptor proteins initiate microglial activation via Toll-like receptor 4 in retinal degeneration mediated by all-trans-retinal. J Biol Chem 288(21):15326–15341. doi:10.1074/jbc.M112.448712
-
(2013)
J Biol Chem
, vol.288
, Issue.21
, pp. 15326-15341
-
-
Kohno, H.1
Chen, Y.2
Kevany, B.M.3
Pearlman, E.4
Miyagi, M.5
Maeda, T.6
Palczewski, K.7
Maeda, A.8
-
68
-
-
6944233576
-
Role of interleukin-1β in the development of retinopathy in rats: effect of antioxidants
-
Kowluru RA, Odenbach S (2004) Role of interleukin-1β in the development of retinopathy in rats: effect of antioxidants. Invest Ophthalmol Vis Sci 45(11):4161–4166. doi:10.1167/iovs.04-0633
-
(2004)
Invest Ophthalmol Vis Sci
, vol.45
, Issue.11
, pp. 4161-4166
-
-
Kowluru, R.A.1
Odenbach, S.2
-
69
-
-
17844392902
-
Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy
-
Krady JK, Basu A, Allen CM, Xu Y, LaNoue KF, Gardner TW, Levison SW (2005) Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy. Diabetes 54(5):1559–1565. doi:10.2337/diabetes.54.5.1559
-
(2005)
Diabetes
, vol.54
, Issue.5
, pp. 1559-1565
-
-
Krady, J.K.1
Basu, A.2
Allen, C.M.3
Xu, Y.4
LaNoue, K.F.5
Gardner, T.W.6
Levison, S.W.7
-
70
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish CL, Chen Y, Blumenschein WM, Mattson J, Basham B, Sedgwick JD, McClanahan T, Kastelein RA, Cua DJ (2005) IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 201(2):233–240. doi:10.1084/jem.20041257
-
(2005)
J Exp Med
, vol.201
, Issue.2
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
McClanahan, T.7
Kastelein, R.A.8
Cua, D.J.9
-
71
-
-
84988966062
-
IL-1β is an innate immune sensor of microbial proteolysis
-
LaRock CN, Todd J, LaRock DL, Olson J, O’Donoghue AJ, Robertson AAB, Cooper MA, Hoffman HM, Nizet V (2016) IL-1β is an innate immune sensor of microbial proteolysis. Sci Immunol 1(2):eaah3539. doi:10.1126/sciimmunol.aah3539
-
(2016)
Sci Immunol
, vol.1
, Issue.2
, pp. eaah3539
-
-
LaRock, C.N.1
Todd, J.2
LaRock, D.L.3
Olson, J.4
O’Donoghue, A.J.5
Robertson, A.A.B.6
Cooper, M.A.7
Hoffman, H.M.8
Nizet, V.9
-
72
-
-
34247170807
-
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
-
Larsen CM, Faulenbach M, Vaag A, Vølund A, Ehses JA, Seifert B, Mandrup-Poulsen T, Donath MY (2007) Interleukin-1-receptor antagonist in type 2 diabetes mellitus. N Engl J Med 356(15):1517–1526. doi:10.1056/NEJMoa065213
-
(2007)
N Engl J Med
, vol.356
, Issue.15
, pp. 1517-1526
-
-
Larsen, C.M.1
Faulenbach, M.2
Vaag, A.3
Vølund, A.4
Ehses, J.A.5
Seifert, B.6
Mandrup-Poulsen, T.7
Donath, M.Y.8
-
73
-
-
69549105888
-
Sustained effects of interleukin-1 receptor antagonist treatment in type 2 diabetes
-
Larsen CM, Faulenbach M, Vaag A, Ehses JA, Donath MY, Mandrup-Poulsen T (2009) Sustained effects of interleukin-1 receptor antagonist treatment in type 2 diabetes. Diabetes Care 32(9):1663–1668. doi:10.2337/dc09-0533
-
(2009)
Diabetes Care
, vol.32
, Issue.9
, pp. 1663-1668
-
-
Larsen, C.M.1
Faulenbach, M.2
Vaag, A.3
Ehses, J.A.4
Donath, M.Y.5
Mandrup-Poulsen, T.6
-
74
-
-
0028675319
-
GM-CSF promotes proliferation of human fetal and adult microglia in primary cultures
-
COI: 1:STN:280:DyaK2M7pslWqtA%3D%3D, PID: 7890333
-
Lee SC, Liu W, Brosnan CF, Dickson DW (1994) GM-CSF promotes proliferation of human fetal and adult microglia in primary cultures. Glia 12(4):309–318
-
(1994)
Glia
, vol.12
, Issue.4
, pp. 309-318
-
-
Lee, S.C.1
Liu, W.2
Brosnan, C.F.3
Dickson, D.W.4
-
75
-
-
84971554433
-
Myeloid cell transmigration across the CNS vasculature triggers IL-1β-driven neuroinflammation during autoimmune encephalomyelitis in mice
-
Lévesque SA, Paré A, Mailhot B, Bellver-Landete V, Kébir H, Lécuyer M-A, Alvarez JI, Prat A, Vaccari JPdR, Keane RW, Lacroix S (2016) Myeloid cell transmigration across the CNS vasculature triggers IL-1β-driven neuroinflammation during autoimmune encephalomyelitis in mice. J Exp Med 213(6):929–949. doi:10.1084/jem.20151437
-
(2016)
J Exp Med
, vol.213
, Issue.6
, pp. 929-949
-
-
Lévesque, S.A.1
Paré, A.2
Mailhot, B.3
Bellver-Landete, V.4
Kébir, H.5
Lécuyer, M.-A.6
Alvarez, J.I.7
Prat, A.8
Vaccari, J.P.R.9
Keane, R.W.10
Lacroix, S.11
-
76
-
-
84861212022
-
IL-1β is upregulated in the diabetic retina and retinal vessels: cell-specific effect of high glucose and IL-1β autostimulation
-
Liu Y, Biarnés Costa M, Gerhardinger C (2012) IL-1β is upregulated in the diabetic retina and retinal vessels: cell-specific effect of high glucose and IL-1β autostimulation. PLoS One 7(5):e36949. doi:10.1371/journal.pone.0036949
-
(2012)
PLoS One
, vol.7
, Issue.5
-
-
Liu, Y.1
Biarnés Costa, M.2
Gerhardinger, C.3
-
77
-
-
85014619076
-
NLRP3 inflammasome activation is associated with proliferative diabetic retinopathy
-
Loukovaara S, Piippo N, Kinnunen K, Hytti M, Kaarniranta K, Kauppinen A (2017) NLRP3 inflammasome activation is associated with proliferative diabetic retinopathy. Acta Ophthalmol (Copenh). doi:10.1111/aos.13427
-
(2017)
Acta Ophthalmol (Copenh)
-
-
Loukovaara, S.1
Piippo, N.2
Kinnunen, K.3
Hytti, M.4
Kaarniranta, K.5
Kauppinen, A.6
-
78
-
-
70349562400
-
Enhanced experimental corneal neovascularization along with aberrant angiogenic factor expression in the absence of IL-1 receptor antagonist
-
Lu P, Li L, Liu G, Zhang X, Mukaida N (2009) Enhanced experimental corneal neovascularization along with aberrant angiogenic factor expression in the absence of IL-1 receptor antagonist. Invest Ophthalmol Vis Sci 50(10):4761–4768. doi:10.1167/iovs.08-2732
-
(2009)
Invest Ophthalmol Vis Sci
, vol.50
, Issue.10
, pp. 4761-4768
-
-
Lu, P.1
Li, L.2
Liu, G.3
Zhang, X.4
Mukaida, N.5
-
79
-
-
84991107707
-
Mechanisms of glutamate toxicity in multiple sclerosis: biomarker and therapeutic opportunities
-
Macrez R, Stys PK, Vivien D, Lipton SA, Docagne F (2016) Mechanisms of glutamate toxicity in multiple sclerosis: biomarker and therapeutic opportunities. Lancet Neurol 15(10):1089–1102. doi:10.1016/S1474-4422(16)30165-X
-
(2016)
Lancet Neurol
, vol.15
, Issue.10
, pp. 1089-1102
-
-
Macrez, R.1
Stys, P.K.2
Vivien, D.3
Lipton, S.A.4
Docagne, F.5
-
80
-
-
0036738398
-
Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets
-
Maedler K, Sergeev P, Ris F, Oberholzer J, Joller-Jemelka HI, Spinas GA, Kaiser N, Halban PA, Donath MY (2002) Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets. J Clin Invest 110(6):851–860. doi:10.1172/jci15318
-
(2002)
J Clin Invest
, vol.110
, Issue.6
, pp. 851-860
-
-
Maedler, K.1
Sergeev, P.2
Ris, F.3
Oberholzer, J.4
Joller-Jemelka, H.I.5
Spinas, G.A.6
Kaiser, N.7
Halban, P.A.8
Donath, M.Y.9
-
81
-
-
84880412453
-
Interleukin-1β alters glutamate transmission at purkinje cell synapses in a mouse model of multiple sclerosis
-
Mandolesi G, Musella A, Gentile A, Grasselli G, Haji N, Sepman H, Fresegna D, Bullitta S, De Vito F, Musumeci G, Di Sanza C, Strata P, Centonze D (2013) Interleukin-1β alters glutamate transmission at purkinje cell synapses in a mouse model of multiple sclerosis. J Neurosci 33(29):12105. doi:10.1523/JNEUROSCI.5369-12.2013
-
(2013)
J Neurosci
, vol.33
, Issue.29
, pp. 12105
-
-
Mandolesi, G.1
Musella, A.2
Gentile, A.3
Grasselli, G.4
Haji, N.5
Sepman, H.6
Fresegna, D.7
Bullitta, S.8
De Vito, F.9
Musumeci, G.10
Di Sanza, C.11
Strata, P.12
Centonze, D.13
-
82
-
-
85014032657
-
The NLRP3 inflammasome is involved in the pathogenesis of Parkinson’s disease in rats
-
Mao Z, Liu C, Ji S, Yang Q, Ye H, Han H, Xue Z (2017) The NLRP3 inflammasome is involved in the pathogenesis of Parkinson’s disease in rats. Neurochem Res 42(4):1104–1115. doi:10.1007/s11064-017-2185-0
-
(2017)
Neurochem Res
, vol.42
, pp. 1104-1115
-
-
Mao, Z.1
Liu, C.2
Ji, S.3
Yang, Q.4
Ye, H.5
Han, H.6
Xue, Z.7
-
83
-
-
33845890803
-
Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation
-
COI: 1:CAS:528:DC%2BD28XhtlChtL7M, PID: 17186029
-
Mariathasan S, Monack DM (2007) Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation. Nat Rev Immunol 7(1):31–40
-
(2007)
Nat Rev Immunol
, vol.7
, Issue.1
, pp. 31-40
-
-
Mariathasan, S.1
Monack, D.M.2
-
84
-
-
0028828583
-
Protective effect of the interleukin-1 receptor antagonist (IL-1ra) on experimental allergic encephalomyelitis in rats
-
Martin D, Near SL (1995) Protective effect of the interleukin-1 receptor antagonist (IL-1ra) on experimental allergic encephalomyelitis in rats. J Neuroimmunol 61(2):241–245. doi:10.1016/0165-5728(95)00108-E
-
(1995)
J Neuroimmunol
, vol.61
, Issue.2
, pp. 241-245
-
-
Martin, D.1
Near, S.L.2
-
85
-
-
84961392860
-
T cell-intrinsic ASC critically promotes TH17-mediated experimental autoimmune encephalomyelitis
-
Martin BN, Wang C, C-j Zhang, Kang Z, Gulen MF, Zepp JA, Zhao J, Bian G, J-s Do, Min B, Pavicic PG Jr, El-Sanadi C, Fox PL, Akitsu A, Iwakura Y, Sarkar A, Wewers MD, Kaiser WJ, Mocarski ES, Rothenberg ME, Hise AG, Dubyak GR, Ransohoff RM, Li X (2016) T cell-intrinsic ASC critically promotes TH17-mediated experimental autoimmune encephalomyelitis. Nat Immunol 17(5):583–592. doi:10.1038/ni.3389
-
(2016)
Nat Immunol
, vol.17
, Issue.5
, pp. 583-592
-
-
Martin, B.N.1
Wang, C.2
Zhang, C.-J.3
Kang, Z.4
Gulen, M.F.5
Zepp, J.A.6
Zhao, J.7
Bian, G.8
Do, J.-S.9
Min, B.10
Pavicic, P.G.11
El-Sanadi, C.12
Fox, P.L.13
Akitsu, A.14
Iwakura, Y.15
Sarkar, A.16
Wewers, M.D.17
Kaiser, W.J.18
Mocarski, E.S.19
Rothenberg, M.E.20
Hise, A.G.21
Dubyak, G.R.22
Ransohoff, R.M.23
Li, X.24
more..
-
86
-
-
84991098162
-
Distinct inflammatory phenotypes of microglia and monocyte-derived macrophages in Alzheimer’s disease models: effects of aging and amyloid pathology
-
Martin E, Boucher C, Fontaine B, Delarasse C (2017) Distinct inflammatory phenotypes of microglia and monocyte-derived macrophages in Alzheimer’s disease models: effects of aging and amyloid pathology. Aging Cell 16(1):27–38. doi:10.1111/acel.12522
-
(2017)
Aging Cell
, vol.16
, Issue.1
, pp. 27-38
-
-
Martin, E.1
Boucher, C.2
Fontaine, B.3
Delarasse, C.4
-
87
-
-
0035883161
-
Interleukin-1β promotes repair of the CNS
-
COI: 1:CAS:528:DC%2BD3MXmvFWhtLY%3D, PID: 11549714
-
Mason JL, Suzuki K, Chaplin DD, Matsushima GK (2001) Interleukin-1β promotes repair of the CNS. J Neurosci 21(18):7046–7052
-
(2001)
J Neurosci
, vol.21
, Issue.18
, pp. 7046-7052
-
-
Mason, J.L.1
Suzuki, K.2
Chaplin, D.D.3
Matsushima, G.K.4
-
88
-
-
84860751910
-
Chronic IL-1β-mediated neuroinflammation mitigates amyloid pathology in a mouse model of Alzheimer’s disease without inducing overt neurodegeneration
-
PID: 22173340
-
Matousek SB, Ghosh S, Shaftel SS, Kyrkanides S, Olschowka JA, O’Banion MK (2012) Chronic IL-1β-mediated neuroinflammation mitigates amyloid pathology in a mouse model of Alzheimer’s disease without inducing overt neurodegeneration. J Neuroimmune Pharmacol 7(1):156–164
-
(2012)
J Neuroimmune Pharmacol
, vol.7
, Issue.1
, pp. 156-164
-
-
Matousek, S.B.1
Ghosh, S.2
Shaftel, S.S.3
Kyrkanides, S.4
Olschowka, J.A.5
O’Banion, M.K.6
-
89
-
-
76449087805
-
Natalizumab treatment in multiple sclerosis: marked decline of chemokines and cytokines in cerebrospinal fluid
-
Mellergård J, Edström M, Vrethem M, Ernerudh J, Dahle C (2010) Natalizumab treatment in multiple sclerosis: marked decline of chemokines and cytokines in cerebrospinal fluid. Mult Scler 16(2):208–217. doi:10.1177/1352458509355068
-
(2010)
Mult Scler
, vol.16
, Issue.2
, pp. 208-217
-
-
Mellergård, J.1
Edström, M.2
Vrethem, M.3
Ernerudh, J.4
Dahle, C.5
-
90
-
-
85010747987
-
Fractalkine signaling attenuates perivascular clustering of microglia and fibrinogen leakage during systemic inflammation in mouse models of diabetic retinopathy
-
Mendiola AS, Garza R, Cardona SM, Mythen SA, Lira SA, Akassoglou K, Cardona AE (2017) Fractalkine signaling attenuates perivascular clustering of microglia and fibrinogen leakage during systemic inflammation in mouse models of diabetic retinopathy. Front Cell Neurosci 10:303. doi:10.3389/fncel.2016.00303
-
(2017)
Front Cell Neurosci
, vol.10
, pp. 303
-
-
Mendiola, A.S.1
Garza, R.2
Cardona, S.M.3
Mythen, S.A.4
Lira, S.A.5
Akassoglou, K.6
Cardona, A.E.7
-
91
-
-
0036224782
-
Caspase activation in retinas of diabetic and galactosemic mice and diabetic patients
-
Mohr S, Xi X, Tang J, Kern TS (2002) Caspase activation in retinas of diabetic and galactosemic mice and diabetic patients. Diabetes 51(4):1172–1179. doi:10.2337/diabetes.51.4.1172
-
(2002)
Diabetes
, vol.51
, Issue.4
, pp. 1172-1179
-
-
Mohr, S.1
Xi, X.2
Tang, J.3
Kern, T.S.4
-
92
-
-
84998773701
-
+ Th17 cells
-
+ Th17 cells. EMBO J. doi:10.15252/embj.201694615
-
(2016)
EMBO J
-
-
Mufazalov, I.A.1
Schelmbauer, C.2
Regen, T.3
Kuschmann, J.4
Wanke, F.5
Gabriel, L.A.6
Hauptmann, J.7
Muller, W.8
Pinteaux, E.9
Kurschus, F.C.10
Waisman, A.11
-
93
-
-
84927661602
-
Inflammasome-independent regulation of IL-1-family cytokines
-
Netea MG, van de Veerdonk FL, van der Meer JWM, Dinarello CA, Joosten LAB (2015) Inflammasome-independent regulation of IL-1-family cytokines. Annu Rev Immunol 33(1):49–77. doi:10.1146/annurev-immunol-032414-112306
-
(2015)
Annu Rev Immunol
, vol.33
, Issue.1
, pp. 49-77
-
-
Netea, M.G.1
van de Veerdonk, F.L.2
van der Meer, J.W.M.3
Dinarello, C.A.4
Joosten, L.A.B.5
-
94
-
-
60149098421
-
Debris clearance by microglia: an essential link between degeneration and regeneration
-
Neumann H, Kotter MR, Franklin RJM (2009) Debris clearance by microglia: an essential link between degeneration and regeneration. Brain 132(2):288–295. doi:10.1093/brain/awn109
-
(2009)
Brain
, vol.132
, Issue.2
, pp. 288-295
-
-
Neumann, H.1
Kotter, M.R.2
Franklin, R.J.M.3
-
95
-
-
18144410635
-
Inflammatory cytokine levels correlate with amyloid load in transgenic mouse models of Alzheimer’s disease
-
Patel NS, Paris D, Mathura V, Quadros AN, Crawford FC, Mullan MJ (2005) Inflammatory cytokine levels correlate with amyloid load in transgenic mouse models of Alzheimer’s disease. J Neuroinflammation 2(1):1
-
(2005)
J Neuroinflammation
, vol.2
, Issue.1
, pp. 1
-
-
Patel, N.S.1
Paris, D.2
Mathura, V.3
Quadros, A.N.4
Crawford, F.C.5
Mullan, M.J.6
-
96
-
-
39449133026
-
Concentration of haemodynamic and inflammatory related cytokines in diabetic retinopathy
-
Patel JI, Saleh GM, Hykin PG, Gregor ZJ, Cree IA (2006) Concentration of haemodynamic and inflammatory related cytokines in diabetic retinopathy. Eye 22(2):223–228. doi:10.1038/sj.eye.6702584
-
(2006)
Eye
, vol.22
, Issue.2
, pp. 223-228
-
-
Patel, J.I.1
Saleh, G.M.2
Hykin, P.G.3
Gregor, Z.J.4
Cree, I.A.5
-
97
-
-
34547791784
-
Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer’s disease
-
Paul J, Strickland S, Melchor JP (2007) Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer’s disease. J Exp Med 204(8):1999. doi:10.1084/jem.20070304
-
(2007)
J Exp Med
, vol.204
, Issue.8
, pp. 1999
-
-
Paul, J.1
Strickland, S.2
Melchor, J.P.3
-
98
-
-
84912033385
-
Increased inflammasome related gene expression profile in PBMC may facilitate T helper 17 cell induction in multiple sclerosis
-
Peelen E, Damoiseaux J, Muris AH, Knippenberg S, Smolders J, Hupperts R, Thewissen M (2015) Increased inflammasome related gene expression profile in PBMC may facilitate T helper 17 cell induction in multiple sclerosis. Mol Immunol 63(2):521–529. doi:10.1016/j.molimm.2014.10.008
-
(2015)
Mol Immunol
, vol.63
, Issue.2
, pp. 521-529
-
-
Peelen, E.1
Damoiseaux, J.2
Muris, A.H.3
Knippenberg, S.4
Smolders, J.5
Hupperts, R.6
Thewissen, M.7
-
99
-
-
80053233055
-
Heterogeneity of CNS myeloid cells and their roles in neurodegeneration
-
Prinz M, Priller J, Sisodia SS, Ransohoff RM (2011) Heterogeneity of CNS myeloid cells and their roles in neurodegeneration. Nat Neurosci 14(10):1227–1235. doi:10.1038/nn.2923
-
(2011)
Nat Neurosci
, vol.14
, Issue.10
, pp. 1227-1235
-
-
Prinz, M.1
Priller, J.2
Sisodia, S.S.3
Ransohoff, R.M.4
-
100
-
-
84885444054
-
Microglia actions in Alzheimer’s disease
-
Prokop S, Miller KR, Heppner FL (2013) Microglia actions in Alzheimer’s disease. Acta Neuropathol 126(4):461–477. doi:10.1007/s00401-013-1182-x
-
(2013)
Acta Neuropathol
, vol.126
, Issue.4
, pp. 461-477
-
-
Prokop, S.1
Miller, K.R.2
Heppner, F.L.3
-
101
-
-
84884281404
-
Using EAE to better understand principles of immune function and autoimmune pathology
-
Rangachari M, Kuchroo VK (2013) Using EAE to better understand principles of immune function and autoimmune pathology. J Autoimmun 45:31–39. doi:10.1016/j.jaut.2013.06.008
-
(2013)
J Autoimmun
, vol.45
, pp. 31-39
-
-
Rangachari, M.1
Kuchroo, V.K.2
-
102
-
-
84930178921
-
T cell subsets and their signature cytokines in autoimmune and inflammatory diseases
-
Raphael I, Nalawade S, Eagar TN, Forsthuber TG (2015) T cell subsets and their signature cytokines in autoimmune and inflammatory diseases. Cytokine 74(1):5–17. doi:10.1016/j.cyto.2014.09.011
-
(2015)
Cytokine
, vol.74
, Issue.1
, pp. 5-17
-
-
Raphael, I.1
Nalawade, S.2
Eagar, T.N.3
Forsthuber, T.G.4
-
103
-
-
84881030866
-
Microglia and interleukin-1beta in ischemic retinopathy elicit microvascular degeneration through neuronal semaphorin-3A
-
Rivera JC, Sitaras N, Noueihed B, Hamel D, Madaan A, Zhou T, Honoré J-C, Quiniou C, Joyal J-S, Hardy P, Sennlaub F, Lubell W, Chemtob S (2013) Microglia and interleukin-1beta in ischemic retinopathy elicit microvascular degeneration through neuronal semaphorin-3A. Arterioscler Thromb Vasc Biol 33(8):1881–1891. doi:10.1161/atvbaha.113.301331
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, Issue.8
, pp. 1881-1891
-
-
Rivera, J.C.1
Sitaras, N.2
Noueihed, B.3
Hamel, D.4
Madaan, A.5
Zhou, T.6
Honoré, J.-C.7
Quiniou, C.8
Joyal, J.-S.9
Hardy, P.10
Sennlaub, F.11
Lubell, W.12
Chemtob, S.13
-
104
-
-
84990982100
-
Interleukin-1beta causes excitotoxic neurodegeneration and multiple sclerosis disease progression by activating the apoptotic protein p53
-
Rossi S, Motta C, Studer V, Macchiarulo G, Volpe E, Barbieri F, Ruocco G, Buttari F, Finardi A, Mancino R, Weiss S, Battistini L, Martino G, Furlan R, Drulovic J, Centonze D (2014) Interleukin-1beta causes excitotoxic neurodegeneration and multiple sclerosis disease progression by activating the apoptotic protein p53. Mol Neurodegener 9:56. doi:10.1186/1750-1326-9-56
-
(2014)
Mol Neurodegener
, vol.9
, pp. 56
-
-
Rossi, S.1
Motta, C.2
Studer, V.3
Macchiarulo, G.4
Volpe, E.5
Barbieri, F.6
Ruocco, G.7
Buttari, F.8
Finardi, A.9
Mancino, R.10
Weiss, S.11
Battistini, L.12
Martino, G.13
Furlan, R.14
Drulovic, J.15
Centonze, D.16
-
105
-
-
72849106266
-
A leaky blood–brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer’s disease brain
-
Ryu JK, McLarnon JG (2009) A leaky blood–brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer’s disease brain. J Cell Mol Med 13(9a):2911–2925. doi:10.1111/j.1582-4934.2008.00434.x
-
(2009)
J Cell Mol Med
, vol.13
, Issue.9a
, pp. 2911-2925
-
-
Ryu, J.K.1
McLarnon, J.G.2
-
106
-
-
0035932121
-
Interleukin-1[beta]-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity
-
Samad TA, Moore KA, Sapirstein A, Billet S, Allchorne A, Poole S, Bonventre JV, Woolf CJ (2001) Interleukin-1[beta]-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature 410(6827):471–475. doi:10.1038/35068566
-
(2001)
Nature
, vol.410
, Issue.6827
, pp. 471-475
-
-
Samad, T.A.1
Moore, K.A.2
Sapirstein, A.3
Billet, S.4
Allchorne, A.5
Poole, S.6
Bonventre, J.V.7
Woolf, C.J.8
-
107
-
-
85007417755
-
The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer’s disease
-
Saresella M, La Rosa F, Piancone F, Zoppis M, Marventano I, Calabrese E, Rainone V, Nemni R, Mancuso R, Clerici M (2016) The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer’s disease. Mol Neurodegener 11:23. doi:10.1186/s13024-016-0088-1
-
(2016)
Mol Neurodegener
, vol.11
, pp. 23
-
-
Saresella, M.1
La Rosa, F.2
Piancone, F.3
Zoppis, M.4
Marventano, I.5
Calabrese, E.6
Rainone, V.7
Nemni, R.8
Mancuso, R.9
Clerici, M.10
-
108
-
-
0034028453
-
The induction of EAE is only partially dependent on TNF receptor signaling but requires the IL-1 type I receptor
-
Schiffenbauer J, Streit WJ, Butfiloski E, LaBow M, Edwards C, Moldawer LL (2000) The induction of EAE is only partially dependent on TNF receptor signaling but requires the IL-1 type I receptor. Clin Immunol 95(2):117–123. doi:10.10006/clim.2000.4851
-
(2000)
Clin Immunol
, vol.95
, Issue.2
, pp. 117-123
-
-
Schiffenbauer, J.1
Streit, W.J.2
Butfiloski, E.3
LaBow, M.4
Edwards, C.5
Moldawer, L.L.6
-
109
-
-
84930475910
-
Different retinal expression patterns of IL-1α, IL-1β, and their receptors in a rat model of type 1 STZ-induced diabetes
-
Scuderi S, D’amico AG, Federico C, Saccone S, Magro G, Bucolo C, Drago F, D’Agata V (2015) Different retinal expression patterns of IL-1α, IL-1β, and their receptors in a rat model of type 1 STZ-induced diabetes. J Mol Neurosci 56(2):431–439. doi:10.1007/s12031-015-0505-x
-
(2015)
J Mol Neurosci
, vol.56
, Issue.2
, pp. 431-439
-
-
Scuderi, S.1
D’amico, A.G.2
Federico, C.3
Saccone, S.4
Magro, G.5
Bucolo, C.6
Drago, F.7
D’Agata, V.8
-
110
-
-
84898792270
-
Cerebrospinal fluid IL-1β correlates with cortical pathology load in multiple sclerosis at clinical onset
-
Seppi D, Puthenparampil M, Federle L, Ruggero S, Toffanin E, Rinaldi F, Perini P, Gallo P (2014) Cerebrospinal fluid IL-1β correlates with cortical pathology load in multiple sclerosis at clinical onset. J Neuroimmunol 270(1–2):56–60. doi:10.1016/j.jneuroim.2014.02.014
-
(2014)
J Neuroimmunol
, vol.270
, Issue.1-2
, pp. 56-60
-
-
Seppi, D.1
Puthenparampil, M.2
Federle, L.3
Ruggero, S.4
Toffanin, E.5
Rinaldi, F.6
Perini, P.7
Gallo, P.8
-
111
-
-
34548434392
-
Chronic interleukin-1β expression in mouse brain leads to leukocyte infiltration and neutrophil-independent blood–brain barrier permeability without overt neurodegeneration
-
Shaftel SS, Carlson TJ, Olschowka JA, Kyrkanides S, Matousek SB, O’Banion MK (2007a) Chronic interleukin-1β expression in mouse brain leads to leukocyte infiltration and neutrophil-independent blood–brain barrier permeability without overt neurodegeneration. J Neurosci 27(35):9301–9309. doi:10.1523/jneurosci.1418-07.2007
-
(2007)
J Neurosci
, vol.27
, Issue.35
, pp. 9301-9309
-
-
Shaftel, S.S.1
Carlson, T.J.2
Olschowka, J.A.3
Kyrkanides, S.4
Matousek, S.B.5
O’Banion, M.K.6
-
112
-
-
34249899174
-
Sustained hippocampal IL-1β overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology
-
COI: 1:CAS:528:DC%2BD2sXmsVWkurg%3D, PID: 17549256
-
Shaftel SS, Kyrkanides S, Olschowka JA, Jen-nie HM, Johnson RE, O’Banion MK (2007b) Sustained hippocampal IL-1β overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology. J Clin Invest 117(6):1595–1604
-
(2007)
J Clin Invest
, vol.117
, Issue.6
, pp. 1595-1604
-
-
Shaftel, S.S.1
Kyrkanides, S.2
Olschowka, J.A.3
Jen-nie, H.M.4
Johnson, R.E.5
O’Banion, M.K.6
-
113
-
-
42649084052
-
The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective
-
Shaftel SS, Griffin WST, O’Banion MK (2008) The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective. J Neuroinflammation 5(1):1
-
(2008)
J Neuroinflammation
, vol.5
, Issue.1
, pp. 1
-
-
Shaftel, S.S.1
Griffin, W.S.T.2
O’Banion, M.K.3
-
114
-
-
0030757323
-
Neuritic plaque evolution in Alzheimer’s disease is accompanied by transition of activated microglia from primed to enlarged to phagocytic forms
-
COI: 1:STN:280:DyaK2szmslyhsg%3D%3D, PID: 9224523
-
Sheng JG, Mrak RE, Griffin WST (1997) Neuritic plaque evolution in Alzheimer’s disease is accompanied by transition of activated microglia from primed to enlarged to phagocytic forms. Acta Neuropathol 94(1):1–5
-
(1997)
Acta Neuropathol
, vol.94
, Issue.1
, pp. 1-5
-
-
Sheng, J.G.1
Mrak, R.E.2
Griffin, W.S.T.3
-
115
-
-
32344440522
-
Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BD28XhvFyjsbs%3D, PID: 16476660
-
Simard AR, Soulet D, Gowing G, Julien J-P, Rivest S (2006) Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer’s disease. Neuron 49(4):489–502
-
(2006)
Neuron
, vol.49
, Issue.4
, pp. 489-502
-
-
Simard, A.R.1
Soulet, D.2
Gowing, G.3
Julien, J.-P.4
Rivest, S.5
-
116
-
-
79955823910
-
Retinal ganglion cell death is induced by microglia derived pro-inflammatory cytokines in the hypoxic neonatal retina
-
Sivakumar V, Foulds WS, Luu CD, Ling E-A, Kaur C (2011) Retinal ganglion cell death is induced by microglia derived pro-inflammatory cytokines in the hypoxic neonatal retina. J Pathol 224(2):245–260. doi:10.1002/path.2858
-
(2011)
J Pathol
, vol.224
, Issue.2
, pp. 245-260
-
-
Sivakumar, V.1
Foulds, W.S.2
Luu, C.D.3
Ling, E.-A.4
Kaur, C.5
-
117
-
-
84966359120
-
Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus
-
Sohn EH, van Dijk HW, Jiao C, Kok PHB, Jeong W, Demirkaya N, Garmager A, Wit F, Kucukevcilioglu M, van Velthoven MEJ, DeVries JH, Mullins RF, Kuehn MH, Schlingemann RO, Sonka M, Verbraak FD, Abràmoff MD (2016) Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus. Proc Natl Acad Sci USA 113(19):E2655–E2664. doi:10.1073/pnas.1522014113
-
(2016)
Proc Natl Acad Sci USA
, vol.113
, Issue.19
, pp. E2655-E2664
-
-
Sohn, E.H.1
van Dijk, H.W.2
Jiao, C.3
Kok, P.H.B.4
Jeong, W.5
Demirkaya, N.6
Garmager, A.7
Wit, F.8
Kucukevcilioglu, M.9
van Velthoven, M.E.J.10
DeVries, J.H.11
Mullins, R.F.12
Kuehn, M.H.13
Schlingemann, R.O.14
Sonka, M.15
Verbraak, F.D.16
Abràmoff, M.D.17
-
118
-
-
84957631835
-
SYSTEMIC INTERLEUKIN 1β INHIBITION IN PROLIFERATIVE DIABETIC RETINOPATHY: a prospective open-label study using canakinumab
-
Stahel M, Becker M, Graf N, Michels S (2016) SYSTEMIC INTERLEUKIN 1β INHIBITION IN PROLIFERATIVE DIABETIC RETINOPATHY: a prospective open-label study using canakinumab. Retina 36(2):385–391. doi:10.1097/IAE.0000000000000701
-
(2016)
Retina
, vol.36
, Issue.2
, pp. 385-391
-
-
Stahel, M.1
Becker, M.2
Graf, N.3
Michels, S.4
-
119
-
-
33745873727
-
A crucial role for interleukin (IL)-1 in the induction of IL-17–producing T cells that mediate autoimmune encephalomyelitis
-
Sutton C, Brereton C, Keogh B, Mills KHG, Lavelle EC (2006) A crucial role for interleukin (IL)-1 in the induction of IL-17–producing T cells that mediate autoimmune encephalomyelitis. J Exp Med 203(7):1685–1691. doi:10.1084/jem.20060285
-
(2006)
J Exp Med
, vol.203
, Issue.7
, pp. 1685-1691
-
-
Sutton, C.1
Brereton, C.2
Keogh, B.3
Mills, K.H.G.4
Lavelle, E.C.5
-
120
-
-
0038416100
-
Interleukin-1β promotes oligodendrocyte death through glutamate excitotoxicity
-
Takahashi JL, Giuliani F, Power C, Imai Y, Yong VW (2003) Interleukin-1β promotes oligodendrocyte death through glutamate excitotoxicity. Ann Neurol 53(5):588–595. doi:10.1002/ana.10519
-
(2003)
Ann Neurol
, vol.53
, Issue.5
, pp. 588-595
-
-
Takahashi, J.L.1
Giuliani, F.2
Power, C.3
Imai, Y.4
Yong, V.W.5
-
121
-
-
79960190061
-
Inflammation in diabetic retinopathy
-
Tang J, Kern TS (2011) Inflammation in diabetic retinopathy. Prog Retin Eye Res 30(5):343–358. doi:10.1016/j.preteyeres.2011.05.002
-
(2011)
Prog Retin Eye Res
, vol.30
, Issue.5
, pp. 343-358
-
-
Tang, J.1
Kern, T.S.2
-
122
-
-
84983262175
-
Photoreceptor cells produce inflammatory mediators that contribute to endothelial cell death in diabetes-induced inflammation in photoreceptors
-
Tonade D, Liu H, Kern TS (2016) Photoreceptor cells produce inflammatory mediators that contribute to endothelial cell death in diabetes-induced inflammation in photoreceptors. Invest Ophthalmol Vis Sci 57(10):4264–4271. doi:10.1167/iovs.16-19859
-
(2016)
Invest Ophthalmol Vis Sci
, vol.57
, Issue.10
, pp. 4264-4271
-
-
Tonade, D.1
Liu, H.2
Kern, T.S.3
-
123
-
-
48249139449
-
Multiple sclerosis: an immune or neurodegenerative disorder?
-
Trapp BD, Nave K-A (2008) Multiple sclerosis: an immune or neurodegenerative disorder? Annu Rev Neurosci 31(1):247–269. doi:10.1146/annurev.neuro.30.051606.094313
-
(2008)
Annu Rev Neurosci
, vol.31
, Issue.1
, pp. 247-269
-
-
Trapp, B.D.1
Nave, K.-A.2
-
124
-
-
84924331611
-
The interleukin-1 receptor antagonist anakinra improves endothelial dysfunction in streptozotocin-induced diabetic rats
-
Vallejo S, Palacios E, Romacho T, Villalobos L, Peiró C, Sánchez-Ferrer CF (2014) The interleukin-1 receptor antagonist anakinra improves endothelial dysfunction in streptozotocin-induced diabetic rats. Cardiovasc Diabetol 13(1):1. doi:10.1186/s12933-014-0158-z
-
(2014)
Cardiovasc Diabetol
, vol.13
, Issue.1
, pp. 1
-
-
Vallejo, S.1
Palacios, E.2
Romacho, T.3
Villalobos, L.4
Peiró, C.5
Sánchez-Ferrer, C.F.6
-
125
-
-
79751512463
-
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
-
Vandanmagsar B, Youm Y-H, Ravussin A, Galgani JE, Stadler K, Mynatt RL, Ravussin E, Stephens JM, Dixit VD (2011) The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat Med 17(2):179–188. doi:10.1038/nm.2279
-
(2011)
Nat Med
, vol.17
, Issue.2
, pp. 179-188
-
-
Vandanmagsar, B.1
Youm, Y.-H.2
Ravussin, A.3
Galgani, J.E.4
Stadler, K.5
Mynatt, R.L.6
Ravussin, E.7
Stephens, J.M.8
Dixit, V.D.9
-
126
-
-
0036353262
-
Interleukin-1 regulates proliferation and differentiation of oligodendrocyte progenitor cells
-
Vela JM, Molina-Holgado E, Arévalo-Martín Á, Almazán G, Guaza C (2002) Interleukin-1 regulates proliferation and differentiation of oligodendrocyte progenitor cells. Mol Cell Neurosci 20(3):489–502. doi:10.1006/mcne.2002.1127
-
(2002)
Mol Cell Neurosci
, vol.20
, Issue.3
, pp. 489-502
-
-
Vela, J.M.1
Molina-Holgado, E.2
Arévalo-Martín, Á.3
Almazán, G.4
Guaza, C.5
-
127
-
-
33847048626
-
Inhibition of caspase-1/interleukin-1β signaling prevents degeneration of retinal capillaries in diabetes and galactosemia
-
Vincent JA, Mohr S (2007) Inhibition of caspase-1/interleukin-1β signaling prevents degeneration of retinal capillaries in diabetes and galactosemia. Diabetes 56(1):224–230. doi:10.2337/db06-0427
-
(2007)
Diabetes
, vol.56
, Issue.1
, pp. 224-230
-
-
Vincent, J.A.1
Mohr, S.2
-
128
-
-
84874446407
-
Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status
-
Vogel DY, Vereyken EJ, Glim JE, Heijnen PD, Moeton M, van der Valk P, Amor S, Teunissen CE, van Horssen J, Dijkstra CD (2013) Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status. J Neuroinflammation 10:35. doi:10.1186/1742-2094-10-35
-
(2013)
J Neuroinflammation
, vol.10
, pp. 35
-
-
Vogel, D.Y.1
Vereyken, E.J.2
Glim, J.E.3
Heijnen, P.D.4
Moeton, M.5
van der Valk, P.6
Amor, S.7
Teunissen, C.E.8
van Horssen, J.9
Dijkstra, C.D.10
-
129
-
-
84870932482
-
Inhibition of IL-12/IL-23 signaling reduces Alzheimer’s disease-like pathology and cognitive decline
-
COI: 1:CAS:528:DC%2BC38XhslahurnJ, PID: 23178247
-
Vom Berg J, Prokop S, Miller KR, Obst J, Kälin RE, Lopategui-Cabezas I, Wegner A, Mair F, Schipke CG, Peters O (2012) Inhibition of IL-12/IL-23 signaling reduces Alzheimer’s disease-like pathology and cognitive decline. Nat Med 18(12):1812–1819
-
(2012)
Nat Med
, vol.18
, Issue.12
, pp. 1812-1819
-
-
Vom Berg, J.1
Prokop, S.2
Miller, K.R.3
Obst, J.4
Kälin, R.E.5
Lopategui-Cabezas, I.6
Wegner, A.7
Mair, F.8
Schipke, C.G.9
Peters, O.10
-
130
-
-
84969286765
-
TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques
-
Wang Y, Ulland TK, Ulrich JD, Song W, Tzaferis JA, Hole JT, Yuan P, Mahan TE, Shi Y, Gilfillan S, Cella M, Grutzendler J, DeMattos RB, Cirrito JR, Holtzman DM, Colonna M (2016) TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques. J Exp Med 213(5):667–675. doi:10.1084/jem.20151948
-
(2016)
J Exp Med
, vol.213
, Issue.5
, pp. 667-675
-
-
Wang, Y.1
Ulland, T.K.2
Ulrich, J.D.3
Song, W.4
Tzaferis, J.A.5
Hole, J.T.6
Yuan, P.7
Mahan, T.E.8
Shi, Y.9
Gilfillan, S.10
Cella, M.11
Grutzendler, J.12
DeMattos, R.B.13
Cirrito, J.R.14
Holtzman, D.M.15
Colonna, M.16
-
131
-
-
79955038882
-
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
-
Wen H, Gris D, Lei Y, Jha S, Zhang L, Huang MT-H, Brickey WJ, Ting JPY (2011) Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nat Immunol 12(5):408–415. doi:10.1038/ni.2022
-
(2011)
Nat Immunol
, vol.12
, Issue.5
, pp. 408-415
-
-
Wen, H.1
Gris, D.2
Lei, Y.3
Jha, S.4
Zhang, L.5
Huang, M.T.-H.6
Brickey, W.J.7
Ting, J.P.Y.8
-
132
-
-
84920990887
-
Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome
-
Yan Y, Jiang W, Liu L, Wang X, Ding C, Tian Z, Zhou R (2015) Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome. Cell 160(1–2):62–73. doi:10.1016/j.cell.2014.11.047
-
(2015)
Cell
, vol.160
, Issue.1-2
, pp. 62-73
-
-
Yan, Y.1
Jiang, W.2
Liu, L.3
Wang, X.4
Ding, C.5
Tian, Z.6
Zhou, R.7
-
133
-
-
84897575371
-
NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke
-
Yang F, Wang Z, Wei X, Han H, Meng X, Zhang Y, Shi W, Li F, Xin T, Pang Q, Yi F (2014) NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke. J Cereb Blood Flow Metab 34(4):660–667. doi:10.1038/jcbfm.2013.242
-
(2014)
J Cereb Blood Flow Metab
, vol.34
, Issue.4
, pp. 660-667
-
-
Yang, F.1
Wang, Z.2
Wei, X.3
Han, H.4
Meng, X.5
Zhang, Y.6
Shi, W.7
Li, F.8
Xin, T.9
Pang, Q.10
Yi, F.11
-
134
-
-
84878767675
-
IL-1β and TNF-α induce neurotoxicity through glutamate production: a potential role for neuronal glutaminase
-
Ye L, Huang Y, Zhao L, Li Y, Sun L, Zhou Y, Qian G, Zheng JC (2013) IL-1β and TNF-α induce neurotoxicity through glutamate production: a potential role for neuronal glutaminase. J Neurochem 125(6):897–908. doi:10.1111/jnc.12263
-
(2013)
J Neurochem
, vol.125
, Issue.6
, pp. 897-908
-
-
Ye, L.1
Huang, Y.2
Zhao, L.3
Li, Y.4
Sun, L.5
Zhou, Y.6
Qian, G.7
Zheng, J.C.8
-
135
-
-
85014128859
-
NLRP3 inflammasome inhibitor ameliorates amyloid pathology in a mouse model of Alzheimer’s disease
-
Yin J, Zhao F, Chojnacki JE, Fulp J, Klein WL, Zhang S, Zhu X (2017) NLRP3 inflammasome inhibitor ameliorates amyloid pathology in a mouse model of Alzheimer’s disease. Mol Neurobiol. doi:10.1007/s12035-017-0467-9
-
(2017)
Mol Neurobiol
-
-
Yin, J.1
Zhao, F.2
Chojnacki, J.E.3
Fulp, J.4
Klein, W.L.5
Zhang, S.6
Zhu, X.7
-
136
-
-
84876907931
-
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer’s disease
-
Zhang B, Gaiteri C, Bodea L-G, Wang Z, McElwee J, Podtelezhnikov AA, Zhang C, Xie T, Tran L, Dobrin R, Fluder E, Clurman B, Melquist S, Narayanan M, Suver C, Shah H, Mahajan M, Gillis T, Mysore J, MacDonald ME, Lamb JR, Bennett DA, Molony C, Stone DJ, Gudnason V, Myers AJ, Schadt EE, Neumann H, Zhu J, Emilsson V (2013) Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer’s disease. Cell 153(3):707–720. doi:10.1016/j.cell.2013.03.030
-
(2013)
Cell
, vol.153
, Issue.3
, pp. 707-720
-
-
Zhang, B.1
Gaiteri, C.2
Bodea, L.-G.3
Wang, Z.4
McElwee, J.5
Podtelezhnikov, A.A.6
Zhang, C.7
Xie, T.8
Tran, L.9
Dobrin, R.10
Fluder, E.11
Clurman, B.12
Melquist, S.13
Narayanan, M.14
Suver, C.15
Shah, H.16
Mahajan, M.17
Gillis, T.18
Mysore, J.19
MacDonald, M.E.20
Lamb, J.R.21
Bennett, D.A.22
Molony, C.23
Stone, D.J.24
Gudnason, V.25
Myers, A.J.26
Schadt, E.E.27
Neumann, H.28
Zhu, J.29
Emilsson, V.30
more..
-
137
-
-
84940760915
-
Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration
-
Zhao L, Zabel MK, Wang X, Ma W, Shah P, Fariss RN, Qian H, Parkhurst CN, Gan WB, Wong WT (2015) Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration. EMBO Mol Med 7(9):1179–1197. doi:10.15252/emmm.201505298
-
(2015)
EMBO Mol Med
, vol.7
, Issue.9
, pp. 1179-1197
-
-
Zhao, L.1
Zabel, M.K.2
Wang, X.3
Ma, W.4
Shah, P.5
Fariss, R.N.6
Qian, H.7
Parkhurst, C.N.8
Gan, W.B.9
Wong, W.T.10
|