메뉴 건너뛰기




Volumn 366, Issue 13, 2012, Pages 1227-1239

Diabetic retinopathy

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BEVACIZUMAB; CANDESARTAN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; ETANERCEPT; FENOFIBRATE; FENOFIBRATE PLUS SIMVASTATIN; FIBRIC ACID DERIVATIVE; FLUOCINOLONE; GELATINASE A; GELATINASE B; INSULIN; LISINOPRIL; LOSARTAN; PEGAPTANIB; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN KINASE C; PROTEIN KINASE C BETA; RANIBIZUMAB; RUBOXISTAURIN; SULFONYLUREA DERIVATIVE; UNCLASSIFIED DRUG;

EID: 84859012407     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMra1005073     Document Type: Article
Times cited : (1407)

References (96)
  • 1
    • 0017912754 scopus 로고
    • Photocoagulation treatment of proliferative diabetic retinopathy: The second report of Diabetic Retinopathy Study findings
    • Photocoagulation treatment of proliferative diabetic retinopathy: the second report of Diabetic Retinopathy Study findings. Ophthalmology 1978;85:82-105.
    • (1978) Ophthalmology , vol.85 , pp. 82-105
  • 2
    • 0022347471 scopus 로고
    • Photocoagulation for diabetic macular edema: Early Treatment Diabetic Retinopathy Study report number 1
    • Photocoagulation for diabetic macular edema: Early Treatment Diabetic Retinopathy Study report number 1. Arch Ophthalmol 1985;103:1796-806.
    • (1985) Arch Ophthalmol , vol.103 , pp. 1796-1806
  • 3
    • 72749093057 scopus 로고    scopus 로고
    • The 25-year incidence of visual impairment in type 1 diabetes mellitus: The Wisconsin Epidemiologic Study of Diabetic Retinopathy
    • Klein R, Lee KE, Gangnon RE, Klein BE. The 25-year incidence of visual impairment in type 1 diabetes mellitus: the Wisconsin Epidemiologic Study of Diabetic Retinopathy. Ophthalmology 2010;117: 63-70.
    • (2010) Ophthalmology , vol.117 , pp. 63-70
    • Klein, R.1    Lee, K.E.2    Gangnon, R.E.3    Klein, B.E.4
  • 5
    • 4143093898 scopus 로고    scopus 로고
    • Declining incidence of severe retinopathy and persisting decrease of nephropathy in an unselected population of Type 1 diabetes - The Linkoping Diabetes Complications Study
    • Nordwall M, Bojestig M, Arnqvist HJ, Ludvigsson J. Declining incidence of severe retinopathy and persisting decrease of nephropathy in an unselected population of Type 1 diabetes - the Linkoping Diabetes Complications Study. Diabetologia 2004;47:1266-72. (Pubitemid 39093322)
    • (2004) Diabetologia , vol.47 , Issue.7 , pp. 1266-1272
    • Nordwall, M.1    Bojestig, M.2    Arnqvist, H.J.3    Ludvigsson, J.4
  • 7
    • 55949129763 scopus 로고    scopus 로고
    • Changes inincidence of diabetes mellitusrelated eye disease among US elderly persons, 1994-2005
    • Sloan FA, Belsky D, Ruiz D Jr, Lee P. Changes inincidence of diabetes mellitusrelated eye disease among US elderly persons, 1994-2005. Arch Ophthalmol 2008; 126:1548-53.
    • (2008) Arch Ophthalmol , vol.126 , pp. 1548-1553
    • Sloan, F.A.1    Belsky, D.2    Ruiz Jr., D.3    Lee, P.4
  • 8
    • 77955383844 scopus 로고    scopus 로고
    • Are individuals with diabetes seeing better? A long-term epidemiological perspective
    • Klein R, Klein BE. Are individuals with diabetes seeing better? A long-term epidemiological perspective. Diabetes 2010; 59:1853-60.
    • (2010) Diabetes , vol.59 , pp. 1853-1860
    • Klein, R.1    Klein, B.E.2
  • 9
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group
    • The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993;329:977- 86.
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 10
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • UK Prospective Diabetes Study (UKPDS) Group. [Erratum, Lancet 1999;354:602.]
    • UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998;352: 837-53. [Erratum, Lancet 1999;354:602.]
    • (1998) Lancet , vol.352 , pp. 837-853
  • 11
    • 0032511580 scopus 로고    scopus 로고
    • Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38
    • Idem
    • Idem. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. BMJ 1998;317:703-13.
    • (1998) BMJ , vol.317 , pp. 703-713
  • 12
    • 67649635807 scopus 로고    scopus 로고
    • Renal and retinal effects of enalapril and losartan in type 1 diabetes
    • Mauer M, Zinman B, Gardiner R, et al. Renal and retinal effects of enalapril and losartan in type 1 diabetes. N Engl J Med 2009;361:40-51.
    • (2009) N Engl J Med , vol.361 , pp. 40-51
    • Mauer, M.1    Zinman, B.2    Gardiner, R.3
  • 13
    • 70350051492 scopus 로고    scopus 로고
    • Trends in medication use among US adults with diabetes mellitus: Glycemic control at the expense of controlling cardiovascular risk factors
    • Mann DM, Woodward M, Ye F, Krousel- Wood M,Muntner P. Trends in medication use among US adults with diabetes mellitus: glycemic control at the expense of controlling cardiovascular risk factors. Arch Intern Med 2009;169:1718-20.
    • (2009) Arch Intern Med , vol.169 , pp. 1718-1720
    • Mann, D.M.1    Woodward, M.2    Ye, F.3    Krousel-Wood, M.4    Muntner, P.5
  • 14
    • 0347133334 scopus 로고    scopus 로고
    • Poor Control of Risk Factors for Vascular Disease among Adults with Previously Diagnosed Diabetes
    • DOI 10.1001/jama.291.3.335
    • Saydah SH, Fradkin J, Cowie CC. Poor control of risk factors for vascular disease among adults with previously diagnosed diabetes. JAMA 2004;291:335-42. (Pubitemid 38101606)
    • (2004) Journal of the American Medical Association , vol.291 , Issue.3 , pp. 335-342
    • Saydah, S.H.1    Fradkin, J.2    Cowie, C.C.3
  • 15
    • 72549103800 scopus 로고    scopus 로고
    • Trends inblood pressure control and treatment among type 2 diabetes with comorbid hypertension in the United States: 1988-2004
    • Suh DC, Kim CM, Choi IS, Plauschinat CA, Barone JA. Trends inblood pressure control and treatment among type 2 diabetes with comorbid hypertension in the United States: 1988-2004. J Hypertens 2009;27:1908-16.
    • (2009) J Hypertens , vol.27 , pp. 1908-1916
    • Suh, D.C.1    Kim, C.M.2    Choi, I.S.3    Plauschinat, C.A.4    Barone, J.A.5
  • 16
    • 2342466734 scopus 로고    scopus 로고
    • Global Prevalence of Diabetes: Estimates for the year 2000 and projections for 2030
    • DOI 10.2337/diacare.27.5.1047
    • Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27: 1047-53. (Pubitemid 38579764)
    • (2004) Diabetes Care , vol.27 , Issue.5 , pp. 1047-1053
    • Wild, S.1    Roglic, G.2    Green, A.3    Sicree, R.4    King, H.5
  • 17
    • 77949262384 scopus 로고    scopus 로고
    • Type 2diabetes mellitus red zone
    • Al-Rubeaan K. Type 2diabetes mellitus red zone. Int J Diabetes Mellitus 2010; 2(1):1-2.
    • (2010) Int J Diabetes Mellitus , vol.2 , Issue.1 , pp. 1-2
    • Al-Rubeaan, K.1
  • 18
    • 23244438018 scopus 로고    scopus 로고
    • Prevalence of diabetic retinopathy in urban India: The Chennai Urban Rural Epidemiology Study (CURES) Eye Study, I
    • DOI 10.1167/iovs.05-0019
    • Rema M, Premkumar S, Anitha B, Deepa R, Pradeepa R, Mohan V. Prevalence of diabetic retinopathy in urban India: the Chennai Urban Rural Epidemiology Study (CURES) eye study, I. Invest Ophthalmol Vis Sci 2005;46:2328-33. (Pubitemid 43119476)
    • (2005) Investigative Ophthalmology and Visual Science , vol.46 , Issue.7 , pp. 2328-2333
    • Rema, M.1    Premkumar, S.2    Anitha, B.3    Deepa, R.4    Pradeepa, R.5    Mohan, V.6
  • 19
    • 77953245215 scopus 로고    scopus 로고
    • Beyond hemoglobin A1c -need for additional markers of risk for diabetic microvascular complications
    • Hirsch IB, Brownlee M. Beyond hemoglobin A1c -need for additional markers of risk for diabetic microvascular complications. JAMA 2010;303:2291-2.
    • (2010) JAMA , vol.303 , pp. 2291-2292
    • Hirsch, I.B.1    Brownlee, M.2
  • 20
    • 0001733320 scopus 로고    scopus 로고
    • The epidemiology of diabetic retinopathy
    • Duh E, ed. Totowa, NJ: Humana
    • Klein R. The epidemiology of diabetic retinopathy. In: Duh E, ed. Diabetic retinopathy. Totowa, NJ: Humana, 2008:67- 107.
    • (2008) Diabetic Retinopathy , pp. 67-107
    • Klein, R.1
  • 21
    • 77950648947 scopus 로고    scopus 로고
    • The prevalence of retinopathy in men with Type 2 diabetes and obstructive sleep apnoea
    • West SD, Groves DC, Lipinski HJ, et al. The prevalence of retinopathy in men with Type 2 diabetes and obstructive sleep apnoea. Diabet Med 2010;27:423-30.
    • (2010) Diabet Med , vol.27 , pp. 423-430
    • West, S.D.1    Groves, D.C.2    Lipinski, H.J.3
  • 22
    • 77955665639 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease is independently associated with an increased prevalence of chronic kidney disease and retinopathy in type 1 diabetic patients
    • Targher G, Bertolini L, Chonchol M, et al. Non-alcoholic fatty liver disease is independently associated with an increased prevalence of chronic kidney disease and retinopathy in type 1 diabetic patients. Diabetologia 2010;53:1341-8.
    • (2010) Diabetologia , vol.53 , pp. 1341-1348
    • Targher, G.1    Bertolini, L.2    Chonchol, M.3
  • 23
    • 78650064127 scopus 로고    scopus 로고
    • High levels of serum prolactin protect against diabetic retinopathy by increasing ocular vasoinhibins
    • Arnold E, Rivera JC, Thebault S, et al. High levels of serum prolactin protect against diabetic retinopathy by increasing ocular vasoinhibins. Diabetes 2010;59: 3192-7.
    • (2010) Diabetes , vol.59 , pp. 3192-3197
    • Arnold, E.1    Rivera, J.C.2    Thebault, S.3
  • 24
    • 56049121492 scopus 로고    scopus 로고
    • Serum levels of adiponectin are associated with diabetic retinopathy and with adiponectin gene mutations in Caucasian patients with diabetes mellitus type 2
    • Zietz B, Buechler C, Kobuch K, Neumeier M, Scholmerich J, Schaffler A. Serum levels of adiponectin are associated with diabetic retinopathy and with adiponectin gene mutations in Caucasian patients with diabetes mellitus type 2. Exp Clin Endocrinol Diabetes 2008;116:532-6.
    • (2008) Exp Clin Endocrinol Diabetes , vol.116 , pp. 532-536
    • Zietz, B.1    Buechler, C.2    Kobuch, K.3    Neumeier, M.4    Scholmerich, J.5    Schaffler, A.6
  • 25
    • 69549112950 scopus 로고    scopus 로고
    • Inflammatory, hemostatic, and other novel biomarkers for diabetic retinopathy: The multi-ethnic study of atherosclerosis
    • Nguyen TT, Alibrahim E, Islam FM, et al. Inflammatory, hemostatic, and other novel biomarkers for diabetic retinopathy: the multi-ethnic study of atherosclerosis. Diabetes Care 2009;32:1704-9.
    • (2009) Diabetes Care , vol.32 , pp. 1704-1709
    • Nguyen, T.T.1    Alibrahim, E.2    Islam, F.M.3
  • 27
    • 67749084303 scopus 로고    scopus 로고
    • Modern-day clinical course of type 1 diabetes mellitus after 30 years' duration: The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications and Pittsburgh Epidemiology of Diabetes Complications experience (1983-2005)
    • Nathan DM, Zinman B, Cleary PA, et al. Modern-day clinical course of type 1 diabetes mellitus after 30 years' duration: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications and Pittsburgh Epidemiology of Diabetes Complications experience (1983-2005). Arch Intern Med 2009;169:1307-16.
    • (2009) Arch Intern Med , vol.169 , pp. 1307-1316
    • Nathan, D.M.1    Zinman, B.2    Cleary, P.A.3
  • 28
    • 0028915217 scopus 로고
    • Progression of retinopathy with intensive versus conventional treatment in the Diabetes Control and Complications Trial
    • Progression of retinopathy with intensive versus conventional treatment in the Diabetes Control and Complications Trial. Ophthalmology 1995;102:647-61.
    • (1995) Ophthalmology , vol.102 , pp. 647-661
  • 30
    • 0035134120 scopus 로고    scopus 로고
    • UKPDS 50: Risk factors for incidence and progression of retinopathy in Type II diabetes over 6 years from diagnosis
    • DOI 10.1007/s001250051594
    • Stratton IM, Kohner EM, Aldington SJ, et al. UKPDS 50: risk factors for incidence and progression of retinopathy in Type II diabetes over 6 years from diagnosis. Diabetologia 2001;44:156-63. (Pubitemid 32156199)
    • (2001) Diabetologia , vol.44 , Issue.2 , pp. 156-163
    • Stratton, I.M.1    Kohner, E.M.2    Aldington, S.J.3    Turner, R.C.4    Holman, R.R.5    Manley, S.E.6    Matthews, D.R.7
  • 31
    • 8144221037 scopus 로고    scopus 로고
    • Risks of progression of retinopathy and vision loss related to tight blood pressure control in type 2 diabetes mellitus: UKPDS 69
    • DOI 10.1001/archopht.122.11.1631
    • Matthews DR, Stratton IM, Aldington SJ, Holman RR, Kohner EM. Risks of progression of retinopathy and vision loss related to tight blood pressure control in type 2 diabetes mellitus: UKPDS 69. Arch Ophthalmol 2004;122:1631-40. (Pubitemid 39473407)
    • (2004) Archives of Ophthalmology , vol.122 , Issue.11 , pp. 1631-1640
    • Matthews, D.R.1    Stratton, I.M.2    Aldington, S.J.3    Holman, R.R.4    Kohner, E.M.5
  • 32
    • 53749100124 scopus 로고    scopus 로고
    • Effect of candesartan on prevention (DIRECT-Prevent 1) and progression (DIRECT-Protect 1) of retinopathy in type 1 diabetes: Randomised, placebo-controlled trials
    • Chaturvedi N, Porta M, Klein R, et al. Effect of candesartan on prevention (DIRECT-Prevent 1) and progression (DIRECT-Protect 1) of retinopathy in type 1 diabetes: randomised, placebo-controlled trials. Lancet 2008;372:1394-402.
    • (2008) Lancet , vol.372 , pp. 1394-1402
    • Chaturvedi, N.1    Porta, M.2    Klein, R.3
  • 33
    • 53749108177 scopus 로고    scopus 로고
    • Effect of candesartan on progression and regression of retinopathy in type 2 diabetes (DIRECT-Protect 2): A randomised placebo- controlled trial
    • Sjølie AK, Klein R, Porta M, et al. Effect of candesartan on progression and regression of retinopathy in type 2 diabetes (DIRECT-Protect 2): a randomised placebo- controlled trial. Lancet 2008;372:1385- 93.
    • (2008) Lancet , vol.372 , pp. 1385-1393
    • Sjølie, A.K.1    Klein, R.2    Porta, M.3
  • 34
    • 0036174019 scopus 로고    scopus 로고
    • Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo
    • Joussen AM, Poulaki V, Qin W, et al. Retinal vascular endothelial growth factor induces intercellular adhesion molecule- 1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo. Am J Pathol 2002;160:501-9. (Pubitemid 34160327)
    • (2002) American Journal of Pathology , vol.160 , Issue.2 , pp. 501-509
    • Joussen, A.M.1    Poulaki, V.2    Qin, W.3    Kirchhof, B.4    Mitsiades, N.5    Wiegand, S.J.6    Rudge, J.7    Yancopoulos, G.D.8    Adamis, A.P.9
  • 35
    • 77952779304 scopus 로고    scopus 로고
    • Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema
    • The Diabetic Retinopathy Clinical Research Network
    • The Diabetic Retinopathy Clinical Research Network. Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. Ophthalmology 2010;117(6):1064.e35- 1077.e35.
    • (2010) Ophthalmology , vol.117 , Issue.6
  • 36
    • 77954654472 scopus 로고    scopus 로고
    • Effects of medical therapies on retinopathy progression in type 2 diabetes
    • The ACCORD Study Group and ACCORD Eye Study Group. [Erratum, N Engl J Med 2011; 364:190.]
    • The ACCORD Study Group and ACCORD Eye Study Group. Effects of medical therapies on retinopathy progression in type 2 diabetes. N Engl J Med 2010; 363:233-44. [Erratum, N Engl J Med 2011; 364:190.]
    • (2010) N Engl J Med , vol.363 , pp. 233-244
  • 38
    • 79960462692 scopus 로고    scopus 로고
    • Medical management of diabetic retinopathy: Fenofibrate and ACCORD Eye studies
    • Lond
    • Wright AD, Dodson PM. Medical management of diabetic retinopathy: fenofibrate and ACCORD Eye studies. Eye (Lond) 2011;25:843-9.
    • (2011) Eye , vol.25 , pp. 843-849
    • Wright, A.D.1    Dodson, P.M.2
  • 39
    • 78049293726 scopus 로고    scopus 로고
    • Two-year outcomes of the Ranibizumab for Edema of the mAcula in Diabetes (READ-2) study
    • Nguyen QD, Shah SM, Khwaja AA, et al. Two-year outcomes of the Ranibizumab for Edema of the mAcula in Diabetes (READ-2) study. Ophthalmology 2010;117: 2146-51.
    • (2010) Ophthalmology , vol.117 , pp. 2146-2151
    • Nguyen, Q.D.1    Shah, S.M.2    Khwaja, A.A.3
  • 40
    • 77952889192 scopus 로고    scopus 로고
    • A prospective randomized trial of intravitreal bevacizumab or laser therapy in the management of diabetic macular edema (BOLT study) 12-month data: Report 2
    • Michaelides M, Kaines A, Hamilton RD, et al. A prospective randomized trial of intravitreal bevacizumab or laser therapy in the management of diabetic macular edema (BOLT study) 12-month data: report 2. Ophthalmology 2010;117(6): 1078.e2-1086.e2.
    • (2010) Ophthalmology , vol.117 , Issue.6
    • Michaelides, M.1    Kaines, A.2    Hamilton, R.D.3
  • 41
    • 79958012399 scopus 로고    scopus 로고
    • A phase 2/3, multicenter, randomized, double-masked, 2-year trial of pegaptanib sodium for the treatment of diabetic macular edema
    • Sultan MB, Zhou D, Loftus J, Dombi T, Ice KS. A phase 2/3, multicenter, randomized, double-masked, 2-year trial of pegaptanib sodium for the treatment of diabetic macular edema. Ophthalmology 2011;118:1107-18.
    • (2011) Ophthalmology , vol.118 , pp. 1107-1118
    • Sultan, M.B.1    Zhou, D.2    Loftus, J.3    Dombi, T.4    Ice, K.S.5
  • 42
    • 79961044911 scopus 로고    scopus 로고
    • Fluocinolone acetonide intravitreal implant for diabetic macular edema: A 3-year multicenter, randomized, controlled clinical trial
    • Pearson PA, Comstock TL, Ip M, et al. Fluocinolone acetonide intravitreal implant for diabetic macular edema: a 3-year multicenter, randomized, controlled clinical trial. Ophthalmology 2011;118:1580- 7.
    • (2011) Ophthalmology , vol.118 , pp. 1580-1587
    • Pearson, P.A.1    Comstock, T.L.2    Ip, M.3
  • 43
    • 79953329178 scopus 로고    scopus 로고
    • Long-term benefit of sustaineddelivery fluocinolone acetonide vitreous inserts for diabetic macular edema
    • Campochiaro PA, Brown DM, Pearson A, et al. Long-term benefit of sustaineddelivery fluocinolone acetonide vitreous inserts for diabetic macular edema. Ophthalmology 2011;118(4):626.e2-635.e2.
    • (2011) Ophthalmology , vol.118 , Issue.4
    • Campochiaro, P.A.1    Brown, D.M.2    Pearson, A.3
  • 44
    • 0036323373 scopus 로고    scopus 로고
    • Hydrocortisone decreases retinal endothelial cell water and solute flux coincident with increased content and decreased phosphorylation of occludin
    • DOI 10.1046/j.0022-3042.2001.00740.x
    • Antonetti DA, Wolpert EB, Demaio L, Harjaj NS, Scaduto RC Jr. Hydrocortisone decreases retinal endothelial cell water and solute flux coincident with increased content and decreased phosphorylation of occludin. J Neurochem 2002;80:667-77. (Pubitemid 34809975)
    • (2002) Journal of Neurochemistry , vol.80 , Issue.4 , pp. 667-677
    • Antonetti, D.A.1    Wolpert, E.B.2    DeMaio, L.3    Harhaj, N.S.4    Scaduto Jr., R.C.5
  • 45
    • 44649151676 scopus 로고    scopus 로고
    • Glucocorticoids induce transactivation of tight junction genes occludin and claudin-5 in retinal endothelial cells via a novel cis-element
    • Felinski EA, Cox AE, Phillips BE, Antonetti DA. Glucocorticoids induce transactivation of tight junction genes occludin and claudin-5 in retinal endothelial cells via a novel cis-element. Exp Eye Res 2008; 86:867-78.
    • (2008) Exp Eye Res , vol.86 , pp. 867-878
    • Felinski, E.A.1    Cox, A.E.2    Phillips, B.E.3    Antonetti, D.A.4
  • 46
    • 67849090567 scopus 로고    scopus 로고
    • Tissue plasminogen activator-mediated PDGF signaling and neurovascular coupling in stroke
    • Su EJ, Fredriksson L, Schielke GP, Eriksson U, Lawrence DA. Tissue plasminogen activator-mediated PDGF signaling and neurovascular coupling in stroke. J Thromb Haemost 2009;7:Suppl 1:155-8.
    • (2009) J Thromb Haemost , vol.7 , Issue.SUPPL. 1 , pp. 155-158
    • Su, E.J.1    Fredriksson, L.2    Schielke, G.P.3    Eriksson, U.4    Lawrence, D.A.5
  • 47
    • 22944483792 scopus 로고    scopus 로고
    • The bloodbrain barrier/neurovascular unit in health and disease
    • Hawkins BT, Davis TP. The bloodbrain barrier/neurovascular unit in health and disease. Pharmacol Rev 2005;57:173- 85.
    • (2005) Pharmacol Rev , vol.57 , pp. 173-185
    • Hawkins, B.T.1    Davis, T.P.2
  • 48
    • 38149090292 scopus 로고    scopus 로고
    • The blood-brain barrier inhealth and chronic neurodegenerative disorders
    • Zlokovic BV. The blood-brain barrier inhealth and chronic neurodegenerative disorders. Neuron 2008;57:178-201.
    • (2008) Neuron , vol.57 , pp. 178-201
    • Zlokovic, B.V.1
  • 49
    • 78651106773 scopus 로고    scopus 로고
    • Review: Molecular pathogenesis of blood-brain barrier breakdown in acute brain injury
    • Nag S, Kapadia A, Stewart DJ. Review: molecular pathogenesis of blood-brain barrier breakdown in acute brain injury. Neuropathol Appl Neurobiol 2011;37:3-23.
    • (2011) Neuropathol Appl Neurobiol , vol.37 , pp. 3-23
    • Nag, S.1    Kapadia, A.2    Stewart, D.J.3
  • 50
    • 74849117723 scopus 로고    scopus 로고
    • The neurovascular unit in the setting of stroke
    • del Zoppo GJ. The neurovascular unit in the setting of stroke. J Intern Med 2010;267:156-71.
    • (2010) J Intern Med , vol.267 , pp. 156-171
    • Del Zoppo, G.J.1
  • 52
    • 33847130442 scopus 로고    scopus 로고
    • Relationship between optical coherence tomography-measured central retinal thickness and visual acuity in diabetic macular edema
    • Diabetic Retinopathy Clinical Research Network
    • Diabetic Retinopathy Clinical Research Network. Relationship between optical coherence tomography-measured central retinal thickness and visual acuity in diabetic macular edema. Ophthalmology 2007;114:525-36.
    • (2007) Ophthalmology , vol.114 , pp. 525-536
  • 53
    • 72349083592 scopus 로고    scopus 로고
    • Diabetic macular oedema and visual loss: Relationship to location, severity and duration
    • Gardner TW, Larsen M, Girach A, Zhi X. Diabetic macular oedema and visual loss: relationship to location, severity and duration. Acta Ophthalmol 2009;87:709- 13.
    • (2009) Acta Ophthalmol , vol.87 , pp. 709-713
    • Gardner, T.W.1    Larsen, M.2    Girach, A.3    Zhi, X.4
  • 54
    • 72249121638 scopus 로고    scopus 로고
    • Müller cellderived VEGF isa significant contributor to retinal neovascularization
    • Bai Y, Ma JX, Guo J, et al. Müller cellderived VEGF isa significant contributor to retinal neovascularization. J Pathol 2009;219:446-54.
    • (2009) J Pathol , vol.219 , pp. 446-454
    • Bai, Y.1    Ma, J.X.2    Guo, J.3
  • 55
    • 77956380383 scopus 로고    scopus 로고
    • Müller cell-derived VEGF isessential for diabetes-induced retinal inflammation and vascular leakage
    • Wang J, Xu X, Elliott MH, Zhu M, Le YZ. Müller cell-derived VEGF isessential for diabetes-induced retinal inflammation and vascular leakage. Diabetes 2010; 59:2297-305.
    • (2010) Diabetes , vol.59 , pp. 2297-2305
    • Wang, J.1    Xu, X.2    Elliott, M.H.3    Zhu, M.4    Le, Y.Z.5
  • 58
    • 68949129005 scopus 로고    scopus 로고
    • Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor- induced permeability
    • Murakami T, Felinski EA, Antonetti DA. Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor- induced permeability. J Biol Chem 2009;284:21036-46.
    • (2009) J Biol Chem , vol.284 , pp. 21036-21046
    • Murakami, T.1    Felinski, E.A.2    Antonetti, D.A.3
  • 59
    • 85171933004 scopus 로고    scopus 로고
    • Protein kinase Cβ phosphorylates occludin regulating tight junction trafficking in vascular endothelial growth factorinduced permeability in vivo
    • in press
    • Murakami T, Frey T, Lin C, Antonetti DA. Protein kinase Cβ phosphorylates occludin regulating tight junction trafficking in vascular endothelial growth factorinduced permeability in vivo. Diabetes (in press).
    • Diabetes
    • Murakami, T.1    Frey, T.2    Lin, C.3    Antonetti, D.A.4
  • 60
    • 33751520614 scopus 로고    scopus 로고
    • Effect of ruboxistaurin on visual loss in patients with diabetic retinopathy
    • The PKC-DRS2 Group
    • The PKC-DRS2 Group. Effect of ruboxistaurin on visual loss in patients with diabetic retinopathy. Ophthalmology 2006;113:2221-30.
    • (2006) Ophthalmology , vol.113 , pp. 2221-2230
  • 61
    • 33947236725 scopus 로고    scopus 로고
    • Effect of ruboxistaurin in patients with diabetic macular edema: Thirty-month results of the randomized PKC-DMES clinical trial
    • Effect of ruboxistaurin in patients with diabetic macular edema: thirty-month results of the randomized PKC-DMES clinical trial. Arch Ophthalmol 2007;125:318- 24.
    • (2007) Arch Ophthalmol , vol.125 , pp. 318-324
  • 63
    • 33846991924 scopus 로고    scopus 로고
    • Extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation
    • Gao BB, Clermont A, Rook S, et al. Extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation. Nat Med 2007;13:181-8.
    • (2007) Nat Med , vol.13 , pp. 181-188
    • Gao, B.B.1    Clermont, A.2    Rook, S.3
  • 64
    • 79959461744 scopus 로고    scopus 로고
    • Plasma kallikrein mediates retinal vascular dysfunction and induces retinal thickening in diabetic rats
    • Clermont A, Chilcote TJ, Kita T, et al. Plasma kallikrein mediates retinal vascular dysfunction and induces retinal thickening in diabetic rats. Diabetes 2011;60: 1590-8.
    • (2011) Diabetes , vol.60 , pp. 1590-1598
    • Clermont, A.1    Chilcote, T.J.2    Kita, T.3
  • 65
    • 77953253715 scopus 로고    scopus 로고
    • Antipermeability function of PEDF involves blockade of the MAP kinase/ GSK/beta-catenin signaling pathway and uPAR expression
    • Yang J, Duh EJ, Caldwell RB, Behzadian MA. Antipermeability function of PEDF involves blockade of the MAP kinase/ GSK/beta-catenin signaling pathway and uPAR expression. Invest Ophthalmol Vis Sci 2010;51:3273-80.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 3273-3280
    • Yang, J.1    Duh, E.J.2    Caldwell, R.B.3    Behzadian, M.A.4
  • 66
    • 34548397756 scopus 로고    scopus 로고
    • Proteolytic degradation of VE-cadherin alters the blood-retinal barrier in diabetes
    • DOI 10.2337/db06-1694
    • Navaratna D, McGuire PG, Menicucci G, Das A. Proteolytic degradation of VE cadherin alters the blood-retinal barrier in diabetes. Diabetes 2007;56:2380-7. (Pubitemid 47358245)
    • (2007) Diabetes , vol.56 , Issue.9 , pp. 2380-2387
    • Navaratna, D.1    McGuire, P.G.2    Menicucci, G.3    Das, A.4
  • 67
    • 18544366585 scopus 로고    scopus 로고
    • Endothelium-specific platelet-derived growth factor-B ablation mimics diabetic retinopathy
    • Enge M, Bjarnegård M, Gerhardt H, et al. Endothelium-specific platelet-derived growth factor-B ablation mimics diabetic retinopathy. EMBO J 2002;21:4307-16.
    • (2002) EMBO J , vol.21 , pp. 4307-4316
    • Enge, M.1    Bjarnegård, M.2    Gerhardt, H.3
  • 68
    • 70449108112 scopus 로고    scopus 로고
    • Activation of PKCdelta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy
    • Geraldes P, Hiraoka-Yamamoto J, Matsumoto M, et al. Activation of PKCdelta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy. Nat Med 2009;15:1298-306.
    • (2009) Nat Med , vol.15 , pp. 1298-1306
    • Geraldes, P.1    Hiraoka-Yamamoto, J.2    Matsumoto, M.3
  • 69
    • 0028123090 scopus 로고
    • Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy
    • Adamis AP, Miller JW, Bernal MT, et al. Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy. Am J Ophthalmol 1994;118:445-50.
    • (1994) Am J Ophthalmol , vol.118 , pp. 445-450
    • Adamis, A.P.1    Miller, J.W.2    Bernal, M.T.3
  • 72
    • 50549089040 scopus 로고    scopus 로고
    • The angio-fibrotic switch of VEGF and CTGF in proliferative diabetic retinopathy
    • Kuiper EJ, Van Nieuwenhoven FA, de Smet MD, et al. The angio-fibrotic switch of VEGF and CTGF in proliferative diabetic retinopathy. PLoS One 2008;3(7): e2675.
    • (2008) PLoS One , vol.3 , Issue.7
    • Kuiper, E.J.1    Van Nieuwenhoven, F.A.2    De Smet, M.D.3
  • 73
    • 79953718348 scopus 로고    scopus 로고
    • The influence of diabetes on glutamate metabolism in retinas
    • Gowda K, Zinnanti WJ, LaNoue KF. The influence of diabetes on glutamate metabolism in retinas. J Neurochem 2011; 117:309-20.
    • (2011) J Neurochem , vol.117 , pp. 309-320
    • Gowda, K.1    Zinnanti, W.J.2    LaNoue, K.F.3
  • 74
    • 54049107380 scopus 로고    scopus 로고
    • Diabetes downregulates presynaptic proteins and reduces basal synapsin 1 phosphorylation in rat retina
    • VanGuilder HD, Brucklacher AR, Patel K, et al. Diabetes downregulates presynaptic proteins and reduces basal synapsin 1 phosphorylation in rat retina. Eur J Neurosci 2008;28:1-11.
    • (2008) Eur J Neurosci , vol.28 , pp. 1-11
    • VanGuilder, H.D.1    Brucklacher, A.R.2    Patel, K.3
  • 77
    • 39049127031 scopus 로고    scopus 로고
    • Microglial activation in human diabetic retinopathy
    • DOI 10.1001/archophthalmol.2007.65
    • Zeng HY, Green WR, Tso MO. Microglial activation inhuman diabetic retinopathy. Arch Ophthalmol 2008;126:227-32. (Pubitemid 351240852)
    • (2008) Archives of Ophthalmology , vol.126 , Issue.2 , pp. 227-232
    • Zeng, H.-Y.1    Green, W.R.2    Tso, M.O.M.3
  • 79
    • 4444317558 scopus 로고    scopus 로고
    • Altered insulin signaling in retinal tissue in diabetic states
    • DOI 10.1074/jbc.M401339200
    • Kondo T, Kahn CR. Altered insulin signaling inretinal tissue in diabetic states. J Biol Chem 2004;279:37997-8006. (Pubitemid 39195515)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.36 , pp. 37997-38006
    • Kondo, T.1    Kahn, C.R.2
  • 80
    • 62649134313 scopus 로고    scopus 로고
    • Diabetes reduces autophosphorylation of retinal insulin receptor and increases protein-tyrosine phosphatase-1B activity
    • Rajala RV, Wiskur B, Tanito M, Callegan M, Rajala A. Diabetes reduces autophosphorylation of retinal insulin receptor and increases protein-tyrosine phosphatase-1B activity. Invest Ophthalmol Vis Sci 2009;50:1033-40.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 1033-1040
    • Rajala, R.V.1    Wiskur, B.2    Tanito, M.3    Callegan, M.4    Rajala, A.5
  • 81
    • 80055062104 scopus 로고    scopus 로고
    • Differential roles of hyperglycemia and hypoinsulinemia in diabetes induced retinal cell death: Evidence for retinal insulin resistance
    • Fort PE, Losiewicz MK, Reiter CEN, et al. Differential roles of hyperglycemia and hypoinsulinemia in diabetes induced retinal cell death: evidence for retinal insulin resistance. PLoS One 2011;6(10): e26498.
    • (2011) PLoS One , vol.6 , Issue.10
    • Fort, P.E.1    Losiewicz, M.K.2    Reiter, C.E.N.3
  • 82
    • 4344599833 scopus 로고    scopus 로고
    • Involvement of brain-derived neurotrophic factor in early retinal neuropathy of streptozotocin-induced diabetes in rats: Therapeutic potential of brain-derived neurotrophic factor for dopaminergic amacrine cells
    • DOI 10.2337/diabetes.53.9.2412
    • Seki M, Tanaka T, Nawa H, et al. Involvement of brain-derived neurotrophic factor in early retinal neuropathy of streptozotocin- induced diabetes in rats: therapeutic potential of brain-derived neurotrophic factor for dopaminergic amacrine cells. Diabetes 2004;53:2412-9. (Pubitemid 39145597)
    • (2004) Diabetes , vol.53 , Issue.9 , pp. 2412-2419
    • Seki, M.1    Tanaka, T.2    Nawa, H.3    Usui, T.4    Fukuchi, T.5    Ikeda, K.6    Abe, H.7    Takei, N.8
  • 84
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006;444:860- 7.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 85
    • 59649118170 scopus 로고    scopus 로고
    • Identification of aretinal aldosterone system and the protective effects of mineralocorticoid receptor antagonism on retinal vascular pathology
    • Wilkinson-Berka JL, Tan G, Jaworski K, Miller AG. Identification of aretinal aldosterone system and the protective effects of mineralocorticoid receptor antagonism on retinal vascular pathology. Circ Res 2009;104:124-33.
    • (2009) Circ Res , vol.104 , pp. 124-133
    • Wilkinson-Berka, J.L.1    Tan, G.2    Jaworski, K.3    Miller, A.G.4
  • 86
    • 0036517850 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNF-alpha suppression
    • Joussen AM, Poulaki V, Mitsiades N, et al. Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNF-alpha suppression. FASEB J 2002; 16:438-40.
    • (2002) FASEB J , vol.16 , pp. 438-440
    • Joussen, A.M.1    Poulaki, V.2    Mitsiades, N.3
  • 87
    • 78049280268 scopus 로고    scopus 로고
    • TNF-alpha signals through PKCzeta/NF-kappaB to alter the tight junction complex and increase retinal endothelial cell permeability
    • Aveleira CA, Lin CM, Abcouwer SF, Ambrosio AF, Antonetti DA. TNF-alpha signals through PKCzeta/NF-kappaB to alter the tight junction complex and increase retinal endothelial cell permeability. Diabetes 2010;59:2872-82.
    • (2010) Diabetes , vol.59 , pp. 2872-2882
    • Aveleira, C.A.1    Lin, C.M.2    Abcouwer, S.F.3    Ambrosio, A.F.4    Antonetti, D.A.5
  • 88
    • 17444405235 scopus 로고    scopus 로고
    • Markers of inflammation are cross-sectionally associated with microvascular complications and cardiovascular disease in type 1 diabetes - The EURODIAB Prospective Complications Study
    • DOI 10.1007/s00125-004-1628-8
    • Schram MT, Chaturvedi N, Schalkwijk CG, Fuller JH, Stehouwer CD. Markers of inflammation are cross-sectionally associated with microvascular complications and cardiovascular disease in type 1 diabetes - the EURODIAB Prospective Complications Study. Diabetologia 2005;48:370-8. (Pubitemid 40543311)
    • (2005) Diabetologia , vol.48 , Issue.2 , pp. 370-378
    • Schram, M.T.1    Chaturvedi, N.2    Schalkwijk, C.G.3    Fuller, J.H.4    Stehouwer, C.D.A.5
  • 89
    • 33845546564 scopus 로고    scopus 로고
    • Determination of vitreous interleukin-1 (IL-1) and tumour necrosis factor (TNF) levels in proliferative diabetic retinopathy
    • DOI 10.1038/sj.eye.6702138, PII 6702138
    • Demircan N, Safran BG, Soylu M, Ozcan AA, Sizmaz S. Determination of vitreous interleukin-1 (IL-1) and tumour necrosis factor (TNF) levels in proliferative diabetic retinopathy. Eye (Lond) 2006; 20:1366-9. (Pubitemid 44921137)
    • (2006) Eye , vol.20 , Issue.12 , pp. 1366-1369
    • Demircan, N.1    Safran, B.G.2    Soylu, M.3    Ozcan, A.A.4    Sizmaz, S.5
  • 91
    • 80055077496 scopus 로고    scopus 로고
    • Prediction, by retinal location, of the onset of diabetic edema in patients with nonproliferative diabetic retinopathy
    • Harrison WW, Bearse MA Jr, Schneck ME, et al. Prediction, by retinal location, of the onset of diabetic edema in patients with nonproliferative diabetic retinopathy. Invest Ophthalmol Vis Sci 2011;52:6825-31.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 6825-6831
    • Harrison, W.W.1    Bearse Jr., M.A.2    Schneck, M.E.3
  • 92
    • 79959719097 scopus 로고    scopus 로고
    • Retinal function inrelation to improved glycaemic control in type 1 diabetes
    • Holfort SK, Norgaard K, Jackson GR, et al. Retinal function inrelation to improved glycaemic control in type 1 diabetes. Diabetologia 2011;54:1853-61.
    • (2011) Diabetologia , vol.54 , pp. 1853-1861
    • Holfort, S.K.1    Norgaard, K.2    Jackson, G.R.3
  • 93
    • 57149118927 scopus 로고    scopus 로고
    • The role of Humphrey Matrix testing in the early diagnosis of retinopathy in type 1 diabetes
    • Parravano M, Oddone F, Mineo D, et al. The role of Humphrey Matrix testing in the early diagnosis of retinopathy in type 1 diabetes. Br J Ophthalmol 2008;92:1656-60.
    • (2008) Br J Ophthalmol , vol.92 , pp. 1656-1660
    • Parravano, M.1    Oddone, F.2    Mineo, D.3
  • 94
    • 85171917915 scopus 로고    scopus 로고
    • Inner retinal visual dysfunction is a sensitive marker of nonproliferative diabetic retinopathy
    • December 15 (Epub ahead of print)
    • Jackson JR, Scott IU, Quillen DA WL, Hershey ME, Gardner TW. Inner retinal visual dysfunction is a sensitive marker of nonproliferative diabetic retinopathy. Br J Ophthalmol 2011 December 15 (Epub ahead of print).
    • (2011) Br J Ophthalmol
    • Jackson, J.R.1    Scott, I.U.2    Quillen, D.A.W.L.3    Hershey, M.E.4    Gardner, T.W.5
  • 95
    • 67649977021 scopus 로고    scopus 로고
    • Selective loss of inner retinal layer thickness in type 1 diabetic patients with minimal diabetic retinopathy
    • van Dijk HW, Kok PH, Garvin M, et al. Selective loss of inner retinal layer thickness in type 1 diabetic patients with minimal diabetic retinopathy. Invest Ophthalmol Vis Sci 2009;50:3404-9.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 3404-3409
    • Van Dijk, H.W.1    Kok, P.H.2    Garvin, M.3
  • 96
    • 77955865169 scopus 로고    scopus 로고
    • Decreased retinal ganglion cell layer thickness in patients with type 1 diabetes
    • van Dijk HW, Verbraak FD, Kok PH, et al. Decreased retinal ganglion cell layer thickness in patients with type 1 diabetes. Invest Ophthalmol Vis Sci 2010;51:3660-5.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 3660-3665
    • Van Dijk, H.W.1    Verbraak, F.D.2    Kok, P.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.