NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 26, 2012, Pages 10480-10485

  Inoue, Makoto ^a   Williams, Kristi L ^a   Gunn, Michael D ^a   Shinohara, Mari L ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Demyelination; Intracerebroventricular injection; Intrathecal injection; Neuroinflammation; Passive experimental autoimmune encephalomyelitis

Indexed keywords

CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CXCR6; CRYOPYRIN; CXCL16 CHEMOKINE; INFLAMMASOME; MONOCYTE CHEMOTACTIC PROTEIN 3; MULTIPROTEIN COMPLEX; OSTEOPONTIN; VERY LATE ACTIVATION ANTIGEN 4;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; C57BL 6 MOUSE; CD4+ T LYMPHOCYTE; CELL MIGRATION; CELL POPULATION; CENTRAL NERVOUS SYSTEM; CHEMOTAXIS; CONTROLLED STUDY; DENDRITIC CELL; EXPERIMENTAL MODEL; HELPER CELL; IMMUNOCOMPETENT CELL; MACROPHAGE; MALE; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; TH17 CELL; UPREGULATION;

ANIMALS; CARRIER PROTEINS; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM; CHEMOTAXIS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; MICE; MICE, KNOCKOUT; T-LYMPHOCYTES;

ANIMALIA; MUS;

EID: 84862988248     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1201836109     Document Type: Article

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