Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration

EMBO Molecular Medicine

Volumn 7, Issue 9, 2015, Pages 1179-1197

  Zhao, Lian ^a   Zabel, Matthew K ^a   Wang, Xu ^a   Ma, Wenxin ^a   Shah, Parth ^a   Fariss, Robert N ^a   Qian, Haohua ^a   Parkhurst, Christopher N ^b   Gan, Wen Biao ^b   Wong, Wai T ^a  

^a NATIONAL EYE INSTITUTE   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Microglia; Phagocytosis; Retinal degeneration; Retinitis pigmentosa

Indexed keywords

VITRONECTIN RECEPTOR; CYCLIC ARGININE-GLYCINE-ASPARTIC ACID PEPTIDE; CYCLOPEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL INFILTRATION; CELL INTERACTION; CELL PHAGOCYTOSIS; CONTROLLED STUDY; GENE INACTIVATION; HUMAN; HUMAN TISSUE; MICROGLIA; MOUSE; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; RETINA DEGENERATION; RETINA ROD; RETINITIS PIGMENTOSA; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL MOTION; DISEASE MODEL; FLUORESCENCE IMAGING; METABOLISM; PATHOLOGY; PHAGOCYTOSIS; PHYSIOLOGY;

ANIMALS; CELL DEATH; CELL MOVEMENT; DISEASE MODELS, ANIMAL; INTEGRIN ALPHAVBETA3; MICE; MICROGLIA; OPTICAL IMAGING; PEPTIDES, CYCLIC; PHAGOCYTOSIS; RETINAL ROD PHOTORECEPTOR CELLS; RETINITIS PIGMENTOSA;

EID: 84940760915     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.15252/emmm.201505298     Document Type: Article

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