Different Retinal Expression Patterns of IL-1α, IL-1β, and Their Receptors in a Rat Model of Type 1 STZ-Induced Diabetes

Journal of Molecular Neuroscience

Volumn 56, Issue 2, 2015, Pages 431-439

  Scuderi, Soraya ^a   D’amico, Agata Grazia ^a   Federico, Concetta ^a   Saccone, Salvatore ^a   Magro, Gaetano ^a   Bucolo, Claudio ^a   Drago, Filippo ^a   D’Agata, Velia ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

Diabetic retinopathy; IL 1 receptor antagonist; IL 1 type I receptor; IL 1 type II receptor; Interleukin 1 ; Interleukin 1

Indexed keywords

EVANS BLUE; GLUCOSE; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1 RECEPTOR TYPE II; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; STREPTOZOCIN; INTERLEUKIN 1 RECEPTOR;

ADULT ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD RETINA BARRIER; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DIABETIC RETINOPATHY; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HYPERGLYCEMIA; IMMUNOREACTIVITY; IN VIVO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; INVESTIGATIVE PROCEDURES; MALE; NERVE CELL; NONHUMAN; PHOTORECEPTOR; PROTEIN EXPRESSION; RAT; RAT MODEL; RETINA DEGENERATION; RETINA INJURY; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; WESTERN BLOTTING; ANIMAL; EXPERIMENTAL DIABETES MELLITUS; GENETICS; METABOLISM; RETINA GANGLION CELL; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DIABETIC RETINOPATHY; INTERLEUKIN-1ALPHA; INTERLEUKIN-1BETA; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, INTERLEUKIN-1; RETINAL GANGLION CELLS;

EID: 84930475910     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-015-0505-x     Document Type: Article

References (38)

1. Abu el Asrar AM, Maimone D, Morse PH, Gregory S, Reder AT (1992) Cytokines in the vitreous of patients with proliferative diabetic retinopathy. Am J Ophthalmol 114(6):731–736
2. Arend WP, Palmer G, Gabay C (2008) IL-1, IL-18, and IL-33 families of cytokines. Immunol Rev 223:20–38
3. Brucklacher RM, Patel KM, VanGuilder HD, Bixler GV, Barber AJ, Antonetti DA, Lin CM, LaNoue KF, Gardner TW, Bronson SK, Freeman WM (2008) Whole genome assessment of the retinal response to diabetes reveals a progressive neurovascular inflammatory response. BMC Med Genomics 1:26
4. Bucolo C, Leggio GM, Drago F, Salomone S (2012) Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats. Biochem Pharmacol 84(1):88–92
5. Bucolo C, Ward KW, Mazzon E, Cuzzocrea S, Drago F (2009) Protective effects of a coumarin derivative in diabetic rats. Invest Ophthalmol Vis Sci 50(8):3846–3852
6. Cabrera DeBuc D, Somfai GM (2010) Early detection of retinal thickness changes in diabetes using Optical Coherence Tomography. Med Sci Monit 16(3):15–21
7. Carmo A, Cunha-Vaz JG, Carvalho AP, Lopes MC (2000) Effect of cyclosporin-A on the blood–retinal barrier permeability in streptozotocin-induced diabetes. Mediators Inflamm 9(5):243–248
8. Chakrabarti S, Cukiernik M, Hileeto D, Evans T, Chen S (2000) Role of vasoactive factors in the pathogenesis of early changes in diabetic retinopathy. Diabetes Metab Res Rev 16(6):393–407
9. Cohen I, Rider P, Carmi Y, Braiman A, Dotan S, White MR, Voronov E, Martin MU, Dinarello CA, Apte RN (2010) Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation. Proc Natl Acad Sci U S A 107(6):2574–2579
10. Cunha-Vaz JG (2004) The blood-retinal barriers system. Basic concepts and clinical evaluation. Exp Eye Res 78(3):715–721
11. D'Amico AG, Scuderi S, Saccone S, Castorina A, Drago F, D'Agata V (2013) Antiproliferative effects of PACAP and VIP in serum-starved glioma cells. J Mol Neurosci 51(2):503–513
12. Demircan N, Safran BG, Soylu M, Ozcan AA, Sizmaz S (2006) Determination of vitreous interleukin-1 (IL-1) and tumour necrosis factor (TNF) levels in proliferative diabetic retinopathy. Eye (Lond) 20(12):1366–1369
13. Feenstra DJ, Yego EC, Mohr S (2013) Modes of retinal cell death in diabetic retinopathy. J Clin Exp Ophthalmol 4(5):298
14. Garlanda C, Dinarello CA, Mantovani A (2013) The interleukin-1 family: back to the future. Immunity 39(6):1003–1018
15. Giunta S, Castorina A, Bucolo C, Magro G, Drago F, D'Agata V (2012) Early changes in pituitary adenylate cyclase-activating peptide, vasoactive intestinal peptide and related receptors expression in retina of streptozotocin-induced diabetic rats. Peptides 37(1):32–39
16. Hoerger TJ, Segel JE, Gregg EW, Saaddine JB (2008) Is glycemic control improving in U.S. adults? Diabetes Care 31(1):81–86
17. Irikura VM, Lagraoui M, Hirsh D (2002) The epistatic interrelationships of IL-1, IL-1 receptor antagonist, and the type I IL-1 receptor. J Immunol 169(1):393–398
18. Kern TS (2007) Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy. Exp Diabetes Res 2007:95103
19. Kim B, Lee Y, Kim E, Kwak A, Ryoo S, Bae SH, Azam T, Kim S, Dinarello CA (2013) The interleukin-1alpha precursor is biologically active and is likely a key alarmin in the IL-1 family of cytokines. Front Immunol 4:391
20. Kowluru RA, Odenbach S (2004) Role of interleukin-1beta in the development of retinopathy in rats: effect of antioxidants. Invest Ophthalmol Vis Sci 45(11):4161–4166
21. Krady JK, Basu A, Allen CM, Xu Y, LaNoue KF, Gardner TW, Levison SW (2005) Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy. Diabetes 54(5):1559–1565
22. Lamacchia C, Rodriguez E, Palmer G, Gabay C (2013) Endogenous IL-1alpha is a chromatin-associated protein in mouse macrophages. Cytokine 63(2):135–144
23. Lieth E, Gardner TW, Barber AJ, Antonetti DA, Penn State Retina Research Group (2000) Retinal neurodegeneration: early pathology in diabetes. Clin Exp Ophthalmol 28(1):3–8
24. Liu X, Ye F, Xiong H, Hu DN, Limb GA, Xie T, Peng L, Zhang P, Wei Y, Zhang W, Wang J, Wu H, Lee P, Song E, Zhang DY (2015) IL-1beta Induces IL-6 production in retinal Muller cells predominantly through the activation of P38 MAPK/NF-kappaB signaling pathway. Exp Cell Res 331(1):223–231
25. Luheshi NM, McColl BW, Brough D (2009) Nuclear retention of IL-1 alpha by necrotic cells: a mechanism to dampen sterile inflammation. Eur J Immunol 39(11):2973–2980
26. Martin PM, Roon P, Van Ells TK, Ganapathy V, Smith S (2004) Death of retinal neurons in streptozotocininduced diabetic mice. Invest Ophthalmol Vis Sc. 45(9):3330–3336
27. Rider P, Carmi Y, Voronov E, Apte RN (2013) Interleukin-1alpha. Semin Immunol 25(6):430–438
28. Rothwell NJ, Luheshi GN (2000) Interleukin 1 in the brain: biology, pathology and therapeutic target. Trends Neurosci 23(12):618–625
29. Rungger-Brandle E, Dosso AA, Leuenberger PM (2000) Glial reactivity, an early feature of diabetic retinopathy. Invest Ophthalmol Vis Sci 41(7):1971–1980
30. Safi SZ, Qvist R, Kumar S, Batumalaie K, Ismail IS (2014) Molecular mechanisms of diabetic retinopathy, general preventive strategies, and novel therapeutic targets. Biomed Res Int 2014:801269
31. Saydah SH, Fradkin J, Cowie CC (2004) Poor control of risk factors for vascular disease among adults with previously diagnosed diabetes. JAMA 291(3):335–342
32. Scuderi S, D'Amico AG, Castorina A, Federico C, Marrazzo G, Drago F, Bucolo C, D'Agata V (2014) Davunetide (NAP) protects the retina against early diabetic injury by reducing apoptotic death. J Mol Neurosci
33. Scuderi S, D'Amico AG, Castorina A, Imbesi R, Carnazza ML, D'Agata V (2013) Ameliorative effect of PACAP and VIP against increased permeability in a model of outer blood retinal barrier dysfunction. Peptides 39:119–124
34. Sedaghat R, Roghani M, Ahmadi M, Ahmadi F (2011) Antihyperglycemic and antihyperlipidemic effect of Rumex patientia seed preparation in streptozotocin-diabetic rats. Pathophysiology 18(2):111–115
35. Sims JE, Dower SK (1994) Interleukin-1 receptors. Eur Cytokine Netw 5(6):539–546
36. Tang J, Kern TS (2011) Inflammation in diabetic retinopathy. Prog Retin Eye Res 30(5):343–358
37. Toda Y, Tsukada J, Misago M, Kominato Y, Auron PE, Tanaka Y (2002) Autocrine induction of the human pro-IL-1beta gene promoter by IL-1beta in monocytes. J Immunol 168(4):1984–1991
38. Yuuki T, Kanda T, Kimura Y, Kotajima N, Tamura J, Kobayashi I, Kishi S (2001) Inflammatory cytokines in vitreous fluid and serum of patients with diabetic vitreoretinopathy. J Diabetes Complicat 15(5):257–259