Chronic interleukin-1β expression in mouse brain leads to leukocyte infiltration and neutrophil-independent blood-brain barrier permeability without overt neurodegeneration

Journal of Neuroscience

Volumn 27, Issue 35, 2007, Pages 9301-9309

  Shaftel, Solomon S ^a   Carlson, Thaddeus J ^a   Olschowka, John A ^a   Kyrkanides, Stephanos ^a   Matousek, Sarah B ^a   O'Banion, M Kerry ^a,b  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Blood Brain barrier; CXCR2; Hippocampus; Interleukin 1 ; Neurotoxicity; Neutrophils

Indexed keywords

CXCL1 CHEMOKINE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; CD45 ANTIGEN; MACROPHAGE INFLAMMATORY PROTEIN 2; MONOKINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CELL INFILTRATION; CONTROLLED STUDY; HIPPOCAMPUS; LEUKOCYTE; MACROPHAGE; MEMBRANE PERMEABILITY; MOUSE; NERVE DEGENERATION; NEUTROPHIL; NONHUMAN; PARENCHYMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TRANSGENE; TRANSGENIC MOUSE; UPREGULATION; ANIMAL; C57BL MOUSE; GENETICS; METABOLISM; PHYSIOLOGY;

ANIMALS; ANTIGENS, CD45; BLOOD-BRAIN BARRIER; CHEMOKINE CCL2; HIPPOCAMPUS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1BETA; LEUKOCYTES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MONOKINES; NEUTROPHILS; UP-REGULATION;

EID: 34548434392     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1418-07.2007     Document Type: Article

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