Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β

PLoS ONE

Volumn 12, Issue 5, 2017, Pages

  Nicholas, Dequina A ^a   Zhang, Kangling ^b   Hung, Christopher ^a   Glasgow, Shane ^a   Aruni, Aruni Wilson ^a   Unternaehrer, Juli ^a   Payne, Kimberly J ^a   Langridge, William H R ^a   De Leon, Marino ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CD1B ANTIGEN; CD1C ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PALMITIC ACID; REACTIVE OXYGEN METABOLITE; T6 ANTIGEN; TOLL LIKE RECEPTOR 4; CD1 ANTIGEN; CD86 PROTEIN, HUMAN; IL1B PROTEIN, HUMAN; IMMUNOGLOBULIN; IMMUNOLOGIC FACTOR; LEUKOCYTE ANTIGEN; LY96 PROTEIN, HUMAN; MEMBRANE PROTEIN; PROTEIN MD 2; RECOMBINANT PROTEIN; TLR4 PROTEIN, HUMAN;

ADULT; ANTIGEN PRESENTATION; ARTICLE; CELL ACTIVATION; CELL MATURATION; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; ENDOCYTOSIS; HEAT; HUMAN; HUMAN CELL; HYDROPHOBICITY; IMMUNE RESPONSE; INFLAMMATION; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR INTERACTION; MOLECULAR MECHANICS; MONOCYTE; NORMAL HUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; TITRIMETRY; UPREGULATION; BINDING SITE; CELL CULTURE; CHEMICAL PHENOMENA; CYTOLOGY; DOSE RESPONSE; HELA CELL LINE; IMMUNOLOGY; METABOLISM; MOLECULAR DOCKING; SECRETION (PROCESS);

ANTIGENS, CD; ANTIGENS, CD1; ANTIGENS, CD86; BINDING SITES; CASPASE 1; CELLS, CULTURED; DENDRITIC CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; HELA CELLS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; IMMUNOGLOBULINS; IMMUNOLOGIC FACTORS; INTERLEUKIN-1BETA; LYMPHOCYTE ANTIGEN 96; MEMBRANE GLYCOPROTEINS; MOLECULAR DOCKING SIMULATION; NF-KAPPA B; PALMITIC ACID; REACTIVE OXYGEN SPECIES; RECOMBINANT PROTEINS; TOLL-LIKE RECEPTOR 4;

EID: 85018971731     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0176793     Document Type: Article

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