Natural killer cell activation by dendritic cells: Balancing inhibitory and activating signals

Cellular and Molecular Life Sciences

Volumn 68, Issue 21, 2011, Pages 3505-3518

  Barreira Da Silva, Rosa ^a,b   Münz, Christian ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

DC editing; Immunological synapse; NK cell priming; Secondary lymphoid organs; Sites of inflammation

Indexed keywords

CD209 ANTIGEN; CD83 ANTIGEN; CD94 ANTIGEN; CHEMOKINE RECEPTOR CCR7; DEATH RECEPTOR 4; FRACTALKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; HIGH MOBILITY GROUP B1 PROTEIN; HLA DR ANTIGEN; HLA E ANTIGEN; INTERLEUKIN 12; INTERLEUKIN 12 RECEPTOR; INTERLEUKIN 15; INTERLEUKIN 15 RECEPTOR ALPHA; INTERLEUKIN 18; INTERLEUKIN 2; INTERLEUKIN 8; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; L SELECTIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3; RANTES; SECONDARY LYMPHOID TISSUE CHEMOKINE;

ADAPTIVE IMMUNITY; AUTOIMMUNITY; BACTERIAL IMMUNITY; CELL COMMUNICATION; CELL INTERACTION; CELL MATURATION; CELL MIGRATION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOMEGALOVIRUS; DENDRITIC CELL; HERPES SIMPLEX VIRUS 1; HUMAN; IMMUNOLOGICAL SYNAPSE; INFLAMMATION; INFLUENZA VIRUS; KIDNEY CARCINOMA; LEISHMANIA MAJOR; LUNG CANCER; LYMPHOCYTE ACTIVATION; LYMPHOID ORGAN; NATURAL KILLER CELL; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NONHUMAN; PARASITE IMMUNITY; PLASMACYTOID DENDRITIC CELL; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION; VESICULAR STOMATITIS VIRUS; VIRUS IMMUNITY;

DENDRITIC CELLS; HUMANS; IMMUNOLOGICAL SYNAPSES; INFLAMMATION; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; SIGNAL TRANSDUCTION;

EID: 80054746187     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-011-0801-8     Document Type: Review

References (167)

1. J Banchereau RM Steinman 1998 Dendritic cells and the control of immunity Nature 392 245 252 9521319 1:CAS:528:DyaK1cXitFWrsr8%3D (Pubitemid 28155090)
2. G Ferlazzo, et al. 2004 Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs Proc Natl Acad Sci USA 101 16606 16611 15536127 1:CAS:528:DC%2BD2cXhtVOisbnP (Pubitemid 39557760)
3. C Caux C Massacrier B Vanbervliet B Dubois C Van Kooten I Durand J Banchereau 1994 Activation of human dendritic cells through CD40 cross-linking J Exp Med 180 1263 1272 7523569 1:CAS:528:DyaK2cXlslOiurw%3D (Pubitemid 24289600)
4. M Cella D Scheidegger K Palmer-Lehmann P Lane A Lanzavecchia G Alber 1996 Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation J Exp Med 184 747 752 8760829 1:CAS:528:DyaK28XltVCrsbc%3D (Pubitemid 26324129)
5. C Reis e Sousa S Hieny T Scharton-Kersten D Jankovic H Charest RN Germain A Sher 1997 In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas J Exp Med 186 1819 1829 9382881 1:CAS:528:DyaK1cXktVOjsLk%3D (Pubitemid 27524592)
6. K Shortman YJ Liu 2002 Mouse and human dendritic cell subtypes Nat Rev Immunol 2 151 161 11913066 1:CAS:528:DC%2BD38XisFaktLc%3D (Pubitemid 37336516)
7. K Shortman SH Naik 2007 Steady-state and inflammatory dendritic-cell development Nat Rev Immunol 7 19 30 17170756 1:CAS:528:DC%2BD28XhtlCht7fF (Pubitemid 46020824)
8. X Ju G Clark DN Hart 2010 Review of human DC subtypes Methods Mol Biol 595 3 20 19941102
9. YJ Liu 2005 IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors Annu Rev Immunol 23 275 306 15771572 1:CAS:528:DC%2BD2MXktFOjur4%3D
10. MC Rissoan V Soumelis N Kadowaki G Grouard F Briere R de Waal Malefyt YJ Liu 1999 Reciprocal control of T helper cell and dendritic cell differentiation Science 283 1183 1186 10024247 1:CAS:528:DyaK1MXhsFegtr4%3D
11. U O'Doherty M Peng S Gezelter WJ Swiggard M Betjes N Bhardwaj RM Steinman 1994 Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature Immunology 82 487 493 7525461 (Pubitemid 24251635)
12. KP MacDonald DJ Munster GJ Clark A Dzionek J Schmitz DN Hart 2002 Characterization of human blood dendritic cell subsets Blood 100 4512 4520 12393628 1:CAS:528:DC%2BD38XpsFCqsbk%3D (Pubitemid 35429692)
13. K Schakel, et al. 2002 6-Sulfo LacNAc, a novel carbohydrate modification of PSGL-1, defines an inflammatory type of human dendritic cells Immunity 17 289 301 12354382 1:CAS:528:DC%2BD38XnsFGrs7c%3D (Pubitemid 35279550)
14. N Romani S Ebner CH Tripp V Flacher F Koch P Stoitzner 2006 Epidermal Langerhans cells-changing views on their function in vivo Immunol Lett 106 119 125 16828878 1:CAS:528:DC%2BD28XotlWhu7Y%3D (Pubitemid 44223748)
15. A Lenz M Heine G Schuler N Romani 1993 Human and murine dermis contain dendritic cells. Isolation by means of a novel method and phenotypical and functional characterization J Clin Invest 92 2587 2596 8254016 1:CAS:528:DyaK2cXkvFCmuw%3D%3D (Pubitemid 24006521)
16. NV Serbina TP Salazar-Mather CA Biron WA Kuziel EG Pamer 2003 TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection Immunity 19 59 70 12871639 1:CAS:528:DC%2BD3sXlvVOrsrg%3D (Pubitemid 36859901)
17. G Hartmann GJ Weiner AM Krieg 1999 CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells Proc Natl Acad Sci USA 96 9305 9310 10430938 1:CAS:528:DyaK1MXltVCjsr4%3D (Pubitemid 29374750)
18. T Sparwasser ES Koch RM Vabulas K Heeg GB Lipford JW Ellwart H Wagner 1998 Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells Eur J Immunol 28 2045 2054 9645386 1:CAS:528:DyaK1cXjsleit7s%3D (Pubitemid 28271721)
19. RM Verdijk T Mutis B Esendam J Kamp CJ Melief A Brand E Goulmy 1999 Polyriboinosinic polyribocytidylic acid (poly(I:C)) induces stable maturation of functionally active human dendritic cells J Immunol 163 57 61 10384099 1:CAS:528:DyaK1MXktF2ruro%3D (Pubitemid 29295824)
20. H Singh-Jasuja HU Scherer N Hilf D Arnold-Schild HG Rammensee RE Toes H Schild 2000 The heat shock protein gp96 induces maturation of dendritic cells and down-regulation of its receptor Eur J Immunol 30 2211 2215 10940912 1:CAS:528:DC%2BD3cXlvFenurg%3D (Pubitemid 30655760)
21. B Sauter ML Albert L Francisco M Larsson S Somersan N Bhardwaj 2000 Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells J Exp Med 191 423 434 10662788 1:CAS:528:DC%2BD3cXhtV2isbg%3D
22. M Cella A Engering V Pinet J Pieters A Lanzavecchia 1997 Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells Nature 388 782 787 9285591 1:CAS:528:DyaK2sXls1Gqt7w%3D (Pubitemid 27375158)
23. S Akira 2003 Mammalian toll-like receptors Curr Opin Immunol 15 5 11 12495726 1:CAS:528:DC%2BD38XpsFegsLw%3D (Pubitemid 35454185)
24. N Kadowaki S Ho S Antonenko RW Malefyt RA Kastelein F Bazan YJ Liu 2001 Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens J Exp Med 194 863 869 11561001 1:CAS:528:DC%2BD3MXmvFGgs7g%3D (Pubitemid 32983021)
25. C Reis e Sousa 2004 Toll-like receptors and dendritic cells: for whom the bug tolls Semin Immunol 16 27 34 14751761 1:CAS:528:DC%2BD2cXntVOntA%3D%3D (Pubitemid 38147431)
26. D Alvarez EH Vollmann UH von Andrian 2008 Mechanisms and consequences of dendritic cell migration Immunity 29 325 342 18799141 1:CAS:528: DC%2BD1cXhtF2jtLvJ
27. M Schnare GM Barton AC Holt K Takeda S Akira R Medzhitov 2001 Toll-like receptors control activation of adaptive immune responses Nat Immunol 2 947 950 11547333 1:CAS:528:DC%2BD3MXnsVCis74%3D (Pubitemid 32976167)
28. D Palliser H Ploegh M Boes 2004 Myeloid differentiation factor 88 is required for cross-priming in vivo J Immunol 172 3415 3421 15004140 1:CAS:528:DC%2BD2cXhvVKjtr0%3D (Pubitemid 38337920)
29. T Ito, et al. 2002 Interferon-alpha and interleukin-12 are induced differentially by toll-like receptor 7 ligands in human blood dendritic cell subsets J Exp Med 195 1507 1512 12045249 1:CAS:528:DC%2BD38XktlGhsbw%3D (Pubitemid 34602828)
30. M Muzio, et al. 2000 Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells J Immunol 164 5998 6004 10820283 1:CAS:528:DC%2BD3cXjslemtbY%3D (Pubitemid 30389848)
31. A Visintin A Mazzoni JH Spitzer DH Wyllie SK Dower DM Segal 2001 Regulation of toll-like receptors in human monocytes and dendritic cells J Immunol 166 249 255 11123299 1:CAS:528:DC%2BD3MXis1aqtg%3D%3D (Pubitemid 32038439)
32. D Jarrossay G Napolitani M Colonna F Sallusto A Lanzavecchia 2001 Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells Eur J Immunol 31 3388 3393 11745357 1:CAS:528:DC%2BD3MXovVSjsrc%3D (Pubitemid 33100532)
33. A Iwasaki R Medzhitov 2004 Toll-like receptor control of the adaptive immune responses Nat Immunol 5 987 995 15454922 1:CAS:528:DC%2BD2cXnvFCgsrg%3D (Pubitemid 41057715)
34. RB Herberman HT Holden 1979 Natural killer cells as antitumor effector cells J Natl Cancer Inst 62 441 445 368406 1:STN:280:DyaE1M7ht1Gqtw%3D%3D (Pubitemid 9122378)
35. R Kiessling E Klein H Pross H Wigzell 1975 "Natural" killer cells in the mouse. II. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Characteristics of the killer cell Eur J Immunol 5 117 121 1086218 1:STN:280:DyaE2s%2FisF2htA%3D%3D
36. JP Di Santo 2006 Natural killer cell developmental pathways: a question of balance Annu Rev Immunol 24 257 286 16551250 1:CAS:528:DC%2BD28XkvFSqt7k%3D
37. LL Lanier AM Le CI Civin MR Loken JH Phillips 1986 The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes J Immunol 136 4480 4486 3086432 1:STN:280:DyaL283isFCktQ%3D%3D (Pubitemid 16090665)
38. JJ Campbell S Qin D Unutmaz D Soler KE Murphy MR Hodge L Wu EC Butcher 2001 Unique subpopulations of CD56+ NK and NK-T peripheral blood lymphocytes identified by chemokine receptor expression repertoire J Immunol 166 6477 6482 11359797 1:CAS:528:DC%2BD3MXjvFart7k%3D (Pubitemid 32467184)
39. R Jacobs G Hintzen A Kemper K Beul S Kempf G Behrens KW Sykora RE Schmidt 2001 CD56bright cells differ in their KIR repertoire and cytotoxic features from CD56dim NK cells Eur J Immunol 31 3121 3127 11592089 1:CAS:528: DC%2BD3MXnvFSgur8%3D
40. MA Cooper TA Fehniger SC Turner KS Chen BA Ghaheri T Ghayur WE Carson MA Caligiuri 2001 Human natural killer cells: a unique innate immunoregulatory role for the CD56(bright) subset Blood 97 3146 3151 11342442 1:CAS:528: DC%2BD3MXjsl2ru74%3D
41. A Moretta C Bottino M Vitale D Pende C Cantoni MC Mingari R Biassoni L Moretta 2001 Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis Annu Rev Immunol 19 197 223 11244035 1:CAS:528:DC%2BD3MXivFKgtbk%3D (Pubitemid 32368034)
42. LL Lanier 2005 NK cell recognition Annu Rev Immunol 23 225 274 15771571 1:CAS:528:DC%2BD2MXktFOjtbc%3D (Pubitemid 40563170)
43. M Champsaur LL Lanier 2010 Effect of NKG2D ligand expression on host immune responses Immunol Rev 235 267 285 20536569 1:CAS:528:DC%2BC3cXnt1Kjt78%3D
44. E Pogge von Strandmann, et al. 2007 Human leukocyte antigen-B-associated transcript 3 is released from tumor cells and engages the NKp30 receptor on natural killer cells Immunity 27 965 974 18055229 1:CAS:528:DC%2BD1cXotFak
45. O Mandelboim, et al. 2001 Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells Nature 409 1055 1060 11234016 1:STN:280:DC%2BD3M7lvFGquw%3D%3D (Pubitemid 32204059)
46. TI Arnon M Lev G Katz Y Chernobrov A Porgador O Mandelboim 2001 Recognition of viral hemagglutinins by NKp44 but not by NKp30 Eur J Immunol 31 2680 2689 11536166 1:CAS:528:DC%2BD3MXntFWjsrk%3D (Pubitemid 32898735)
47. EN Nolte-'t Hoen CR Almeida NR Cohen S Nedvetzki H Yarwood DM Davis 2007 Increased surveillance of cells in mitosis by human NK cells suggests a novel strategy for limiting tumor growth and viral replication Blood 109 670 673 16960147 (Pubitemid 46105968)
48. A Moretta, et al. 1990 Identification of four subsets of human CD3-CD16+ natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition J Exp Med 172 1589 1598 2147946 1:CAS:528:DyaK3cXmtV2msr0%3D
49. NM Valiante, et al. 1997 Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors Immunity 7 739 751 9430220 1:CAS:528:DyaK1cXjsV2ltA%3D%3D (Pubitemid 28064888)
50. GB Cohen RT Gandhi DM Davis O Mandelboim BK Chen JL Strominger D Baltimore 1999 The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells Immunity 10 661 671 10403641 1:CAS:528:DyaK1MXksVSmsLk%3D (Pubitemid 29302919)
51. TA Fehniger MA Cooper GJ Nuovo M Cella F Facchetti M Colonna MA Caligiuri 2003 CD56bright natural killer cells are present in human lymph nodes and are activated by T cell-derived IL-2: a potential new link between adaptive and innate immunity Blood 101 3052 3057 12480696 1:CAS:528:DC%2BD3sXjtFCqt78%3D (Pubitemid 36857995)
52. G Ferlazzo D Thomas SL Lin K Goodman B Morandi WA Muller A Moretta C Munz 2004 The abundant NK cells in human secondary lymphoid tissues require activation to express killer cell Ig-like receptors and become cytolytic J Immunol 172 1455 1462 14734722 1:CAS:528:DC%2BD2cXptlyrsw%3D%3D (Pubitemid 38116788)
53. J Westermann R Pabst 1992 Distribution of lymphocyte subsets and natural killer cells in the human body Clin Investig 70 539 544 1392422 1:STN:280:DyaK3s%2FgsFeqsA%3D%3D
54. S Chen H Kawashima JB Lowe LL Lanier M Fukuda 2005 Suppression of tumor formation in lymph nodes by l-selectin-mediated natural killer cell recruitment J Exp Med 202 1679 1689 16352740 1:CAS:528:DC%2BD2MXhtlCjsrjJ (Pubitemid 41815874)
55. CH Kim LM Pelus E Appelbaum K Johanson N Anzai HE Broxmeyer 1999 CCR7 ligands, SLC/6Ckine/Exodus2/TCA4 and CKbeta-11/MIP-3beta/ELC, are chemoattractants for CD56(+)CD16(-) NK cells and late stage lymphoid progenitors Cell Immunol 193 226 235 10222066 1:CAS:528:DyaK1MXislWktb8%3D (Pubitemid 29228369)
56. M Frey NB Packianathan TA Fehniger ME Ross WC Wang CC Stewart MA Caligiuri SS Evans 1998 Differential expression and function of l-selectin on CD56bright and CD56dim natural killer cell subsets J Immunol 161 400 408 9647249 1:CAS:528:DyaK1cXktVynsb4%3D (Pubitemid 28285548)
57. KR Garrod SH Wei I Parker MD Cahalan 2007 Natural killer cells actively patrol peripheral lymph nodes forming stable conjugates to eliminate MHC-mismatched targets Proc Natl Acad Sci USA 104 12081 12086 17609379 1:CAS:528:DC%2BD2sXosVWhtbo%3D (Pubitemid 47185633)
58. M Bajenoff B Breart AY Huang H Qi J Cazareth VM Braud RN Germain N Glaichenhaus 2006 Natural killer cell behavior in lymph nodes revealed by static and real-time imaging J Exp Med 203 619 631 16505138 1:CAS:528: DC%2BD28XjsVSqtbk%3D
59. H Beuneu J Deguine B Breart O Mandelboim JP Di Santo P Bousso 2009 Dynamic behavior of NK cells during activation in lymph nodes Blood 114 3227 3234 19667398 1:CAS:528:DC%2BD1MXhtlShtbnN
60. T Walzer, et al. 2007 Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46 Proc Natl Acad Sci USA 104 3384 3389 17360655 1:CAS:528:DC%2BD2sXjtVWlt7Y%3D (Pubitemid 46364168)
61. A Martin-Fontecha LL Thomsen S Brett C Gerard M Lipp A Lanzavecchia F Sallusto 2004 Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming Nat Immunol 5 1260 1265 15531883 1:CAS:528: DC%2BD2cXpvV2rsb0%3D (Pubitemid 41057741)
62. SV Watt DM Andrews K Takeda MJ Smyth Y Hayakawa 2008 IFN-gamma-dependent recruitment of mature CD27(high) NK cells to lymph nodes primed by dendritic cells J Immunol 181 5323 5330 18832688 1:CAS:528:DC%2BD1cXhtF2hs7bP
63. Y Hayakawa MJ Smyth 2006 CD27 dissects mature NK cells into two subsets with distinct responsiveness and migratory capacity J Immunol 176 1517 1524 16424180 1:CAS:528:DC%2BD28XlsFygtg%3D%3D (Pubitemid 43134295)
64. JA Kummer AM Kamp TM Tadema W Vos CJ Meijer CE Hack 1995 Localization and identification of granzymes A and B-expressing cells in normal human lymphoid tissue and peripheral blood Clin Exp Immunol 100 164 172 7697916 1:STN:280:DyaK2M3ht1SmsQ%3D%3D
65. E Vivier M Munroe P Ariniello P Anderson 1995 Identification of tissue-infiltrating lymphocytes expressing PEN5, a mucin-like glycoprotein selectively expressed on natural killer cells Am J Pathol 146 409 418 7531954 1:CAS:528:DyaK2MXkslahtr0%3D
66. W Timens S Poppema 1985 Lymphocyte compartments in human spleen. An immunohistologic study in normal spleens and uninvolved spleens in Hodgkin's disease Am J Pathol 120 443 454 3898859 1:STN:280:DyaL2MzgsVertg%3D%3D (Pubitemid 15250106)
67. TP Salazar-Mather R Ishikawa CA Biron 1996 NK cell trafficking and cytokine expression in splenic compartments after IFN induction and viral infection J Immunol 157 3054 3064 8816415 1:CAS:528:DyaK28XlvVWmurk%3D (Pubitemid 126450065)
68. C Gregoire, et al. 2008 Intrasplenic trafficking of natural killer cells is redirected by chemokines upon inflammation Eur J Immunol 38 2076 2084 18624307 1:CAS:528:DC%2BD1cXhtVCltrrF
69. FP Huang GG MacPherson 2001 Continuing education of the immune system-dendritic cells, immune regulation and tolerance Curr Mol Med 1 457 468 11899090 1:CAS:528:DC%2BD3MXmsVOgt7k%3D
70. MC Dieu, et al. 1998 Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites J Exp Med 188 373 386 9670049 1:CAS:528:DyaK1cXkvVaqtLo%3D
71. F Sallusto P Schaerli P Loetscher C Schaniel D Lenig CR Mackay S Qin A Lanzavecchia 1998 Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation Eur J Immunol 28 2760 2769 9754563 1:CAS:528:DyaK1cXmtFahtL4%3D (Pubitemid 28425234)
72. S Sozzani, et al. 1997 Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines J Immunol 159 1993 2000 9257866 1:CAS:528:DyaK2sXltlGitL8%3D (Pubitemid 127484190)
73. M Bajenoff S Granjeaud S Guerder 2003 The strategy of T cell antigen-presenting cell encounter in antigen-draining lymph nodes revealed by imaging of initial T cell activation J Exp Med 198 715 724 12953093 1:CAS:528:DC%2BD3sXntFeqt70%3D (Pubitemid 37087771)
74. SA Luther HL Tang PL Hyman AG Farr JG Cyster 2000 Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse Proc Natl Acad Sci USA 97 12694 12699 11070085 1:CAS:528:DC%2BD3cXotFyns7s%3D
75. NJ Megjugorac HA Young SB Amrute SL Olshalsky P Fitzgerald-Bocarsly 2004 Virally stimulated plasmacytoid dendritic cells produce chemokines and induce migration of T and NK cells J Leukoc Biol 75 504 514 14742635 1:CAS:528:DC%2BD2cXis1ehs7Y%3D (Pubitemid 38316382)
76. P Carrega, et al. 2008 Natural killer cells infiltrating human nonsmall-cell lung cancer are enriched in CD56 bright CD16(-) cells and display an impaired capability to kill tumor cells Cancer 112 863 875 18203207 (Pubitemid 351240580)
77. JS Schleypen, et al. 2006 Cytotoxic markers and frequency predict functional capacity of natural killer cells infiltrating renal cell carcinoma Clin Cancer Res 12 718 725 16467081 1:CAS:528:DC%2BD28XhtFeitb0%3D (Pubitemid 43259850)
78. JS Schleypen M Von Geldern EH Weiss N Kotzias K Rohrmann DJ Schendel CS Falk H Pohla 2003 Renal cell carcinoma-infiltrating natural killer cells express differential repertoires of activating and inhibitory receptors and are inhibited by specific HLA class I allotypes Int J Cancer 106 905 912 12918068 1:CAS:528:DC%2BD3sXnsVGrsb8%3D (Pubitemid 37071669)
79. N Dalbeth R Gundle RJ Davies YC Lee AJ McMichael MF Callan 2004 CD56bright NK cells are enriched at inflammatory sites and can engage with monocytes in a reciprocal program of activation J Immunol 173 6418 6426 15528382 1:CAS:528:DC%2BD2cXpt1Olurw%3D (Pubitemid 39487802)
80. K Karre HG Ljunggren G Piontek R Kiessling 1986 Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy Nature 319 675 678 3951539 1:STN:280:DyaL287ks1yguw%3D%3D (Pubitemid 16119452)
81. MF van den Broek D Kagi RM Zinkernagel H Hengartner 1995 Perforin dependence of natural killer cell-mediated tumor control in vivo Eur J Immunol 25 3514 3516 8566046 (Pubitemid 26004963)
82. H Arase ES Mocarski AE Campbell AB Hill LL Lanier 2002 Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors Science 296 1323 1326 11950999 1:CAS:528:DC%2BD38Xjsl2qu78%3D (Pubitemid 34522789)
83. HR Smith, et al. 2002 Recognition of a virus-encoded ligand by a natural killer cell activation receptor Proc Natl Acad Sci USA 99 8826 8831 12060703 1:CAS:528:DC%2BD38XltF2ht70%3D (Pubitemid 34693643)
84. NC Fernandez, et al. 1999 Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo Nat Med 5 405 411 10202929 1:CAS:528:DyaK1MXisFOltrg%3D (Pubitemid 29180578)
85. F Gerosa B Baldani-Guerra C Nisii V Marchesini G Carra G Trinchieri 2002 Reciprocal activating interaction between natural killer cells and dendritic cells J Exp Med 195 327 333 11828007 1:CAS:528:DC%2BD38Xht1Wjt7o%3D (Pubitemid 34461490)
86. D Piccioli S Sbrana E Melandri NM Valiante 2002 Contact-dependent stimulation and inhibition of dendritic cells by natural killer cells J Exp Med 195 335 341 11828008 1:CAS:528:DC%2BD38Xht1Wjt7s%3D (Pubitemid 34461491)
87. G Ferlazzo ML Tsang L Moretta G Melioli RM Steinman C Munz 2002 Human dendritic cells activate resting natural killer (NK) cells and are recognized via the NKp30 receptor by activated NK cells J Exp Med 195 343 351 11828009 1:CAS:528:DC%2BD38Xht1Wjt7g%3D (Pubitemid 34461492)
88. SH Kassim NK Rajasagi X Zhao R Chervenak SR Jennings 2006 In vivo ablation of CD11c-positive dendritic cells increases susceptibility to herpes simplex virus type 1 infection and diminishes NK and T-cell responses J Virol 80 3985 3993 16571815 1:CAS:528:DC%2BD28Xjs1Srurs%3D
89. M Lucas W Schachterle K Oberle P Aichele A Diefenbach 2007 Dendritic cells prime natural killer cells by trans-presenting interleukin 15 Immunity 26 503 517 17398124 1:CAS:528:DC%2BD2sXltVKjs7Y%3D (Pubitemid 46602996)
90. F Gerosa A Gobbi P Zorzi S Burg F Briere G Carra G Trinchieri 2005 The reciprocal interaction of NK cells with plasmacytoid or myeloid dendritic cells profoundly affects innate resistance functions J Immunol 174 727 734 15634892 1:CAS:528:DC%2BD2MXotFWn (Pubitemid 40094266)
91. KB Nguyen, et al. 2002 Coordinated and distinct roles for IFN-alpha beta, IL-12, and IL-15 regulation of NK cell responses to viral infection J Immunol 169 4279 4287 12370359 1:CAS:528:DC%2BD38XnvFGntbY%3D (Pubitemid 35178200)
92. JS Orange CA Biron 1996 Characterization of early IL-12, IFN-alphabeta, and TNF effects on antiviral state and NK cell responses during murine cytomegalovirus infection J Immunol 156 4746 4756 8648121 1:CAS:528: DyaK28XjsFamtbs%3D (Pubitemid 26174459)
93. M Dalod T Hamilton R Salomon TP Salazar-Mather SC Henry JD Hamilton CA Biron 2003 Dendritic cell responses to early murine cytomegalovirus infection: subset functional specialization and differential regulation by interferon alpha/beta J Exp Med 197 885 898 12682109 1:CAS:528:DC%2BD3sXivFaisb8%3D (Pubitemid 36437865)
94. M Dalod TP Salazar-Mather L Malmgaard C Lewis C Asselin-Paturel F Briere G Trinchieri CA Biron 2002 Interferon alpha/beta and interleukin 12 responses to viral infections: pathways regulating dendritic cell cytokine expression in vivo J Exp Med 195 517 528 11854364 1:CAS:528:DC%2BD38XhslOrt7c%3D (Pubitemid 34461304)
95. M Swiecki S Gilfillan W Vermi Y Wang M Colonna 2010 Plasmacytoid dendritic cell ablation impacts early interferon responses and antiviral NK and CD8(+) T cell accrual Immunity 33 955 966 21130004 1:CAS:528:DC%2BC3cXhsFyisLvO
96. C Asselin-Paturel, et al. 2001 Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology Nat Immunol 2 1144 1150 11713464 1:CAS:528:DC%2BD3MXptVait7s%3D (Pubitemid 33130149)
97. R Barbalat L Lau RM Locksley GM Barton 2009 Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands Nat Immunol 10 1200 1207 19801985 1:CAS:528: DC%2BD1MXht1Wgsb%2FP
98. E Szomolanyi-Tsuda X Liang RM Welsh EA Kurt-Jones RW Finberg 2006 Role for TLR2 in NK cell-mediated control of murine cytomegalovirus in vivo J Virol 80 4286 4291 16611887 1:CAS:528:DC%2BD28Xkt1Oku70%3D
99. K Tabeta, et al. 2004 Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection Proc Natl Acad Sci USA 101 3516 3521 14993594 1:CAS:528:DC%2BD2cXisFWmsbc%3D (Pubitemid 38338227)
100. A Krug, et al. 2004 TLR9-dependent recognition of MCMV by IPC and DC generates coordinated cytokine responses that activate antiviral NK cell function Immunity 21 107 119 15345224 1:CAS:528:DC%2BD2cXmtlKjt7w%3D (Pubitemid 38925271)
101. CE Andoniou, et al. 2005 Interaction between conventional dendritic cells and natural killer cells is integral to the activation of effective antiviral immunity Nat Immunol 6 1011 1019 16142239 1:CAS:528:DC%2BD2MXhtVajs7fK (Pubitemid 41486186)
102. DM Andrews CE Andoniou AA Scalzo SL van Dommelen ME Wallace MJ Smyth MA Degli-Esposti 2005 Cross-talk between dendritic cells and natural killer cells in viral infection Mol Immunol 42 547 555 15607812 1:CAS:528:DC%2BD2cXhtVyktrbO (Pubitemid 39655967)
103. G Pollara, et al. 2004 Herpes simplex virus type-1-induced activation of myeloid dendritic cells: the roles of virus cell interaction and paracrine type I IFN secretion J Immunol 173 4108 4119 15356161 1:CAS:528:DC%2BD2cXnsVWkurg%3D (Pubitemid 39280776)
104. JS Orange CA Biron 1996 An absolute and restricted requirement for IL-12 in natural killer cell IFN-gamma production and antiviral defense. Studies of natural killer and T cell responses in contrasting viral infections J Immunol 156 1138 1142 8557990 1:CAS:528:DyaK28XmtlOqug%3D%3D
105. T Strowig F Brilot F Arrey G Bougras D Thomas WA Muller C Munz 2008 Tonsilar NK cells restrict B cell transformation by the Epstein-Barr virus via IFN-gamma PLoS Pathog 4 e27 18266470
106. JM Monteiro C Harvey G Trinchieri 1998 Role of interleukin-12 in primary influenza virus infection J Virol 72 4825 4831 9573248 1:CAS:528: DyaK1cXjtVeitr4%3D (Pubitemid 28215659)
107. T Scharton-Kersten LC Afonso M Wysocka G Trinchieri P Scott 1995 IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis J Immunol 154 5320 5330 7730635 1:CAS:528:DyaK2MXlsVyktLo%3D
108. T Nomura, et al. 2002 Essential role of interleukin-12 (IL-12) and IL-18 for gamma interferon production induced by listeriolysin O in mouse spleen cells Infect Immun 70 1049 1055 11854182 1:CAS:528:DC%2BD38XhsFSmurY%3D (Pubitemid 34163373)
109. F Granucci I Zanoni N Pavelka SL Van Dommelen CE Andoniou F Belardelli MA Degli Esposti P Ricciardi-Castagnoli 2004 A contribution of mouse dendritic cell-derived IL-2 for NK cell activation J Exp Med 200 287 295 15289500 1:CAS:528:DC%2BD2cXmsVCktbk%3D (Pubitemid 39031248)
110. R Koka PR Burkett M Chien S Chai F Chan JP Lodolce DL Boone A Ma 2003 Interleukin (IL)-15R[alpha]-deficient natural killer cells survive in normal but not IL-15R[alpha]-deficient mice J Exp Med 197 977 984 12695489 1:CAS:528:DC%2BD3sXjt1Wlsrg%3D (Pubitemid 36523195)
111. MK Kennedy, et al. 2000 Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice J Exp Med 191 771 780 10704459 1:CAS:528:DC%2BD3cXhslygtrc%3D
112. JP Lodolce DL Boone S Chai RE Swain T Dassopoulos S Trettin A Ma 1998 IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation Immunity 9 669 676 9846488 1:CAS:528:DyaK1cXnvFWktLY%3D (Pubitemid 28557595)
113. F Brilot T Strowig SM Roberts F Arrey C Munz 2007 NK cell survival mediated through the regulatory synapse with human DCs requires IL-15Ralpha J Clin Invest 117 3316 3329 17948125 1:CAS:528:DC%2BD2sXht12isrjP (Pubitemid 350096988)
114. ND Huntington, et al. 2007 Interleukin 15-mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1 Nat Immunol 8 856 863 17618288 1:CAS:528:DC%2BD2sXnvFejsbo%3D (Pubitemid 47103041)
115. E Mortier T Woo R Advincula S Gozalo A Ma 2008 IL-15Ralpha chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation J Exp Med 205 1213 1225 18458113 1:CAS:528: DC%2BD1cXlvFWrsL8%3D (Pubitemid 351679694)
116. ND Huntington, et al. 2009 IL-15 trans-presentation promotes human NK cell development and differentiation in vivo J Exp Med 206 25 34 19103877 1:CAS:528:DC%2BD1MXhtVOhtbw%3D
117. Elpek KG, Rubinstein MP, Bellemare-Pelletier A, Goldrath AW and Turley SJ (2010). Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15/IL-15R{alpha} complexes. Proc Natl Acad Sci USA (in press)
118. DE Oppenheim SJ Roberts SL Clarke R Filler JM Lewis RE Tigelaar M Girardi AC Hayday 2005 Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance Nat Immunol 6 928 937 16116470 1:CAS:528:DC%2BD2MXos1eqtL0%3D (Pubitemid 43090448)
119. T Saito R Ruffman RD Welker RB Herberman MA Chirigos 1985 Development of hyporesponsiveness of natural killer cells to augmentation of activity after multiple treatments with biological response modifiers Cancer Immunol Immunother 19 130 135 3845849 1:STN:280:DyaL2M7ns1Gltg%3D%3D (Pubitemid 15067079)
120. SK Tripathy PA Keyel L Yang JT Pingel TP Cheng A Schneeberger WM Yokoyama 2008 Continuous engagement of a self-specific activation receptor induces NK cell tolerance J Exp Med 205 1829 1841 18606857 1:CAS:528:DC%2BD1cXpsFOjsL4%3D
121. C Münz T Dao G Ferlazzo MA de Cos K Goodman JW Young 2005 Mature myeloid dendritic cell subsets have distinct roles for activation and viability of circulating human natural killer cells Blood 105 266 273 15331446 (Pubitemid 40053092)
122. C Borg, et al. 2004 NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs Blood 104 3267 3275 15242871 1:CAS:528:DC%2BD2cXhtVWhurrJ (Pubitemid 39507145)
123. C Semino G Angelini A Poggi A Rubartelli 2005 NK/iDC interaction results in IL-18 secretion by DCs at the synaptic cleft followed by NK cell activation and release of the DC maturation factor HMGB1 Blood 106 609 616 15802534 1:CAS:528:DC%2BD2MXmtleqtrY%3D (Pubitemid 40981258)
124. NC Fernandez C Flament F Crepineau E Angevin E Vivier L Zitvogel 2002 Dendritic cells (DC) promote natural killer (NK) cell functions: dynamics of the human DC/NK cell cross talk Eur Cytokine Netw 13 17 27 11956017 1:CAS:528:DC%2BD38Xkt1Smtrs%3D (Pubitemid 34535568)
125. KC Newman DS Korbel JC Hafalla EM Riley 2006 Cross-talk with myeloid accessory cells regulates human natural killer cell interferon-gamma responses to malaria PLoS Pathog 2 e118 17154717
126. S Hanabuchi N Watanabe YH Wang T Ito J Shaw W Cao FX Qin YJ Liu 2006 Human plasmacytoid predendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand (GITRL) Blood 107 3617 3623 16397134 1:CAS:528:DC%2BD28Xkt1Giur8%3D
127. M Jinushi, et al. 2003 Critical role of MHC class I-related chain A and B expression on IFN-alpha-stimulated dendritic cells in NK cell activation: impairment in chronic hepatitis C virus infection J Immunol 170 1249 1256 12538683 1:CAS:528:DC%2BD3sXnvVOmtA%3D%3D (Pubitemid 36139490)
128. M Terme, et al. 2004 IL-4 confers NK stimulatory capacity to murine dendritic cells: a signaling pathway involving KARAP/DAP12-triggering receptor expressed on myeloid cell 2 molecules J Immunol 172 5957 5966 15128777 1:CAS:528:DC%2BD2cXjs1OjtLw%3D (Pubitemid 38621195)
129. A Poggi, et al. 2002 NK cell activation by dendritic cells is dependent on LFA-1-mediated induction of calcium-calmodulin kinase II: inhibition by HIV-1 Tat C-terminal domain J Immunol 168 95 101 11751951 1:CAS:528: DC%2BD38Xht1Ghtg%3D%3D (Pubitemid 34014107)
130. O Carpen I Virtanen VP Lehto E Saksela 1983 Polarization of NK cell cytoskeleton upon conjugation with sensitive target cells J Immunol 131 2695 2698 6417230 1:STN:280:DyaL2c%2Fmt12msw%3D%3D (Pubitemid 14208816)
131. O Carpen I Virtanen E Saksela 1982 Ultrastructure of human natural killer cells: nature of the cytolytic contacts in relation to cellular secretion J Immunol 128 2691 2697 7077081 1:STN:280:DyaL387ptFShtA%3D%3D (Pubitemid 12124500)
132. ML Dustin EO Long 2010 Cytotoxic immunological synapses Immunol Rev 235 24 34 20536553 1:CAS:528:DC%2BC3cXnt1Kjsbs%3D
133. JS Orange 2008 Formation and function of the lytic NK-cell immunological synapse Nat Rev Immunol 8 713 725 19172692 1:CAS:528:DC%2BD1cXhtVamu7bM
134. M Masilamani C Nguyen J Kabat F Borrego JE Coligan 2006 CD94/NKG2A inhibits NK cell activation by disrupting the actin network at the immunological synapse J Immunol 177 3590 3596 16951318 1:CAS:528:DC%2BD28XptlOhu7w%3D (Pubitemid 44359890)
135. J Endt FE McCann CR Almeida D Urlaub R Leung D Pende DM Davis C Watzl 2007 Inhibitory receptor signals suppress ligation-induced recruitment of NKG2D to GM1-rich membrane domains at the human NK cell immune synapse J Immunol 178 5606 5611 17442943 1:CAS:528:DC%2BD2sXktlWiu78%3D (Pubitemid 46674356)
136. JP Medema, et al. 2001 Expression of the serpin serine protease inhibitor 6 protects dendritic cells from cytotoxic T lymphocyte-induced apoptosis: differential modulation by T helper type 1 and type 2 cells J Exp Med 194 657 667 11535633 1:CAS:528:DC%2BD3MXms1KhsLg%3D (Pubitemid 32844775)
137. CE Hirst MS Buzza CH Bird HS Warren PU Cameron M Zhang PG Ashton-Rickardt PI Bird 2003 The intracellular granzyme B inhibitor, proteinase inhibitor 9, is up-regulated during accessory cell maturation and effector cell degranulation, and its overexpression enhances CTL potency J Immunol 170 805 815 12517944 1:CAS:528:DC%2BD3sXktlGntw%3D%3D (Pubitemid 36070532)
138. D Messmer H Yang G Telusma F Knoll J Li B Messmer KJ Tracey N Chiorazzi 2004 High mobility group box protein 1: an endogenous signal for dendritic cell maturation and Th1 polarization J Immunol 173 307 313 15210788 1:CAS:528:DC%2BD2cXltVaju7k%3D (Pubitemid 38797355)
139. JR Pallandre, et al. 2008 Dendritic cell and natural killer cell cross-talk: a pivotal role of CX3CL1 in NK cytoskeleton organization and activation Blood 112 4420 4424 18682600 1:CAS:528:DC%2BD1cXhsVCltbzK
140. MM Al-Alwan G Rowden TD Lee KA West 2001 The dendritic cell cytoskeleton is critical for the formation of the immunological synapse J Immunol 166 1452 1456 11160183 1:CAS:528:DC%2BD3MXhtVSjt7c%3D (Pubitemid 32114622)
141. L Riol-Blanco, et al. 2009 Immunological synapse formation inhibits, via NF-kappaB and FOXO1, the apoptosis of dendritic cells Nat Immunol 10 753 760 19503105 1:CAS:528:DC%2BD1MXntVWisL4%3D
142. M Vitale M Della Chiesa S Carlomagno C Romagnani A Thiel L Moretta A Moretta 2004 The small subset of CD56brightCD16- natural killer cells is selectively responsible for both cell proliferation and interferon-gamma production upon interaction with dendritic cells Eur J Immunol 34 1715 1722 15162442 1:CAS:528:DC%2BD2cXltFKqsrw%3D (Pubitemid 39256054)
143. Strowig T, Chijioke O, Carrega P, Arrey F, Meixlsperger S, Ramer PC, Ferlazzo G and Munz C (2010). Human NK cells of mice with reconstituted human immune system components require pre-activation to acquire functional competence. Blood (in press)
144. A Moretta 2002 Natural killer cells and dendritic cells: rendezvous in abused tissues Nat Rev Immunol 2 957 964 12461568 1:CAS:528:DC%2BD38XptFKnu7Y%3D (Pubitemid 37323216)
145. A Lunemann JD Lunemann S Roberts B Messmer R Barreira da Silva CS Raine C Munz 2008 Human NK cells kill resting but not activated microglia via NKG2D- and NKp46-mediated recognition J Immunol 181 6170 6177 18941207 1:CAS:528:DC%2BD1cXht1KrtrjL
146. JA Hamerman JR Jarjoura MB Humphrey MC Nakamura WE Seaman LL Lanier 2006 Cutting edge: inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12 J Immunol 177 2051 2055 16887962 1:CAS:528:DC%2BD28Xns1Kht74%3D (Pubitemid 44200961)
147. S Nedvetzki, et al. 2007 Reciprocal regulation of human natural killer cells and macrophages associated with distinct immune synapses Blood 109 3776 3785 17218381 1:CAS:528:DC%2BD2sXkvFCitL8%3D (Pubitemid 46641728)
148. J Siren T Sareneva J Pirhonen M Strengell V Veckman I Julkunen S Matikainen 2004 Cytokine and contact-dependent activation of natural killer cells by influenza A or Sendai virus-infected macrophages J Gen Virol 85 2357 2364 15269377 1:CAS:528:DC%2BD2cXmvVKhtrc%3D (Pubitemid 39162608)
149. PD Shah SM Gilbertson DA Rowley 1985 Dendritic cells that have interacted with antigen are targets for natural killer cells J Exp Med 162 625 636 3160806 1:STN:280:DyaL2M3mtlCitw%3D%3D (Pubitemid 15249964)
150. JL Wilson LC Heffler J Charo A Scheynius MT Bejarano HG Ljunggren 1999 Targeting of human dendritic cells by autologous NK cells J Immunol 163 6365 6370 10586025 1:CAS:528:DyaK1MXotFSiurc%3D
151. E Carbone G Terrazzano G Ruggiero D Zanzi A Ottaiano C Manzo K Karre S Zappacosta 1999 Recognition of autologous dendritic cells by human NK cells Eur J Immunol 29 4022 4029 10602012 1:CAS:528:DyaK1MXotVehsL4%3D
152. G Ferlazzo B Morandi A D'Agostino R Meazza G Melioli A Moretta L Moretta 2003 The interaction between NK cells and dendritic cells in bacterial infections results in rapid induction of NK cell activation and in the lysis of uninfected dendritic cells Eur J Immunol 33 306 313 12548561 1:CAS:528:DC%2BD3sXhtlOktL8%3D (Pubitemid 36267594)
153. MT Melki H Saidi A Dufour JC Olivo-Marin ML Gougeon 2010 Escape of HIV-1-infected dendritic cells from TRAIL-mediated NK cell cytotoxicity during NK-DC cross-talk-a pivotal role of HMGB1 PLoS Pathog 6 e1000862 20419158
154. D Pende, et al. 2006 Expression of the DNAM-1 ligands, Nectin-2 (CD112) and poliovirus receptor (CD155), on dendritic cells: relevance for natural killer-dendritic cell interaction Blood 107 2030 2036 16304049 1:CAS:528:DC%2BD28XitFCht7k%3D (Pubitemid 43289387)
155. GM Spaggiari R Carosio D Pende S Marcenaro P Rivera MR Zocchi L Moretta A Poggi 2001 NK cell-mediated lysis of autologous antigen-presenting cells is triggered by the engagement of the phosphatidylinositol 3-kinase upon ligation of the natural cytotoxicity receptors NKp30 and NKp46 Eur J Immunol 31 1656 1665 11385609 1:CAS:528:DC%2BD3MXksFKjsL0%3D (Pubitemid 32547327)
156. M Della Chiesa M Vitale S Carlomagno G Ferlazzo L Moretta A Moretta 2003 The natural killer cell-mediated killing of autologous dendritic cells is confined to a cell subset expressing CD94/NKG2A, but lacking inhibitory killer Ig-like receptors Eur J Immunol 33 1657 1666 12778484 1:CAS:528: DC%2BD3sXkvF2rtbs%3D (Pubitemid 36790427)
157. Y Hayakawa V Screpanti H Yagita A Grandien HG Ljunggren MJ Smyth BJ Chambers 2004 NK cell TRAIL eliminates immature dendritic cells in vivo and limits dendritic cell vaccination efficacy J Immunol 172 123 129 14688317 1:CAS:528:DC%2BD3sXpvFeht7w%3D (Pubitemid 38020463)
158. S Laffont C Seillet J Ortaldo JD Coudert JC Guery 2008 Natural killer cells recruited into lymph nodes inhibit alloreactive T-cell activation through perforin-mediated killing of donor allogeneic dendritic cells Blood 112 661 671 18505782 1:CAS:528:DC%2BD1cXpsVaju7k%3D
159. L Ruggeri, et al. 2002 Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants Science 295 2097 2100 11896281 1:CAS:528:DC%2BD38Xit1Ohurs%3D (Pubitemid 34229476)
160. G Yu X Xu MD Vu ED Kilpatrick XC Li 2006 NK cells promote transplant tolerance by killing donor antigen-presenting cells J Exp Med 203 1851 1858 16864660 1:CAS:528:DC%2BD28Xotleis7g%3D (Pubitemid 44188459)
161. SJ Kang HE Liang B Reizis RM Locksley 2008 Regulation of hierarchical clustering and activation of innate immune cells by dendritic cells Immunity 29 819 833 19006696 1:CAS:528:DC%2BD1cXhsVehtbjL
162. M Vitale M Della Chiesa S Carlomagno D Pende M Arico L Moretta A Moretta 2005 NK-dependent DC maturation is mediated by TNFalpha and IFNgamma released upon engagement of the NKp30 triggering receptor Blood 106 566 571 15784725 1:CAS:528:DC%2BD2MXmtleqtrw%3D (Pubitemid 40981252)
163. R Mocikat, et al. 2003 Natural killer cells activated by MHC class I(low) targets prime dendritic cells to induce protective CD8 T cell responses Immunity 19 561 569 14563320 1:CAS:528:DC%2BD3sXosF2rsrs%3D (Pubitemid 37311437)
164. B Morandi G Bougras WA Muller G Ferlazzo C Munz 2006 NK cells of human secondary lymphoid tissues enhance T cell polarization via IFN-gamma secretion Eur J Immunol 36 2394 2400 16917961 1:CAS:528:DC%2BD28XhtVWgs7%2FI (Pubitemid 44420596)
165. Y Laouar FS Sutterwala L Gorelik RA Flavell 2005 Transforming growth factor-beta controls T helper type 1 cell development through regulation of natural killer cell interferon-gamma Nat Immunol 6 600 607 15852008 1:CAS:528:DC%2BD2MXktlWitrs%3D (Pubitemid 41710731)
166. R Ing MM Stevenson 2009 Dendritic cell and NK cell reciprocal cross talk promotes gamma interferon-dependent immunity to blood-stage Plasmodium chabaudi AS infection in mice Infect Immun 77 770 782 19015248 1:CAS:528: DC%2BD1MXhs1ShsLg%3D
167. C Adam, et al. 2005 DC-NK cell cross talk as a novel CD4+ T-cell-independent pathway for antitumor CTL induction Blood 106 338 344 15769894 1:CAS:528:DC%2BD2MXlvVWjt74%3D (Pubitemid 40967210)